Mitochondrial permeability transition as a source of superoxide anion induced by the nitroaromatic drug nimesulide in vitro

Free Radical Biology and Medicine

Volumn 39, Issue 7, 2005, Pages 949-959

  Tay, Vincent K S ^a   Wang, Audrey S ^a   Leow, Koon Yeow ^a   Ong, Michie M K ^a   Wong, Kim Ping ^a   Boelsterli, Urs A ^a,b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Free radicals; Membrane permeability transition; Mitochondria; Nimesulide; Nitroaromatic drug; Superoxide anion; Uncoupling

Indexed keywords

ADENOSINE TRIPHOSPHATE; AROMATIC NITRO COMPOUND; CYCLOSPORIN A; FLUORESCENT DYE; HYDROETHIDINE; NIMESULIDE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

ANIMAL EXPERIMENT; ARTICLE; BIOSYNTHESIS; CELL MEMBRANE PERMEABILITY; CELL METABOLISM; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG INHIBITION; FEMALE; IN VITRO STUDY; LIVER MITOCHONDRION; MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 31344433881     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2005.05.013     Document Type: Article

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