Opposing regulation of ciliary neurotrophic factor receptors on neuroblastoma cells by distinct differentiating agents

Journal of Neurobiology

Volumn 32, Issue 1, 1997, Pages 81-94

  Malek, Renae L ^a   Halvorsen, Stanley W ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

cytokine; mRNA; neurotrophic factor receptors; protein kinase C; retinoic acid

Indexed keywords

CILIARY NEUROTROPHIC FACTOR; CYCLOHEXIMIDE; DACTINOMYCIN; PHORBOL 13 ACETATE 12 MYRISTATE; RECEPTOR SUBUNIT; RETINOIC ACID; RIBONUCLEASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE EXPRESSION REGULATION; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; TRANSCRIPTION REGULATION; TRANSLATION REGULATION;

ANTINEOPLASTIC AGENTS; BINDING SITES; CARCINOGENS; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IODINE RADIOISOTOPES; NEUROBLASTOMA; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; PROTEIN KINASE C; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTOR, CILIARY NEUROTROPHIC FACTOR; RECEPTORS, NERVE GROWTH FACTOR; RNA, MESSENGER; SENSITIVITY AND SPECIFICITY; STAT3 TRANSCRIPTION FACTOR; TETRADECANOYLPHORBOL ACETATE; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TRETINOIN; TUMOR CELLS, CULTURED;

EID: 0031022782     PISSN: 00223034     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4695(199701)32:1<81::AID-NEU8>3.0.CO;2-A     Document Type: Article

References (64)

1. ADEM, A., MATTSSON, M. E. K., NORDBERG, A., and PÅHLMAN, S. (1987). Muscarinic receptors in human SHSY5Y neuroblastoma cell line: regulation by phorbol ester and retinoic acid-induced differentiation. Dev. Brain Res. 33:235-242.
2. ADLER, R., LANDA, K., MANTHORPE, M., and VARON, S. (1979). Cholinergic neurotrophic factors: intraocular distribution of soluble trophic activity for ciliary neurons. Science 204:1434-1436.
3. BARDE, Y.-A. (1989). Trophic factors and neuronal survival. Neuron 2:1525-1534.
4. BAZAN, J. F. (1989). A novel family of growth factor receptors: a common binding domain in the growth hormone, prolactin, erythropoietin and IL-6 receptors. Biochem. Biophys. Res. Commun. 164:788-795.
5. BIEDLER, J., HELSON, L., and SPENGLER, B. (1973). Morphology and growth, tumorigenicity and cytogenetics of human neuroblastoma cells in continuous culture. Cancer Res. 33:2643-2652.
6. BLOTTNER, D., BRUGGMAN, W., and UNSICKER, K. (1989). Ciliary neurotrophic factor supports target-derived preganglionic sympathetic spinal cord neurons. Neurosci. Lett. 105:316-320.
7. BOULTON, T. G., STAHL, N., and YANCOPOULOS, G. D. (1994). Ciliary neurotrophic factor, leukemia inhibitory factor, interleukin-6, oncostatin-M family of cytokines induces tyrosine phosphorylation of a common set of proteins overlapping those induced by other cytokines and growth factors. J. Biol. Chem. 269:11648-11655.
8. CLAGETT-DAME, M., VERHALEN, T., BIEDLER. J. L., and REPA, J. J. (1993). Identification and characterization of all-trans-retinoic acid receptor transcripts and receptor protein in human neuroblastoma cells. Arch. Biochem. Biophys. 300:684-693.
9. DAVIS, S., ALDRICH, T., STAHL, N., IP, N., and YANCOPOULOS, G. (1993). LIFRβ and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor. Science 260:1805-1808.
10. DAVIS, S., ALDRICH, T., VALENZUELA, D., WONG, V., FURTH, M., SQUINTO, S., and YANCOPOULOS, G. (1991). The receptor for ciliary neurotrophic factor. Science 253:59-63.
11. DECHIARA, T., VEJSADA, R., POUEYMIROU, W., ACHESON, A., SURI, C., CONOVER, J., FRIEDMAN, B., MCCLAIN, J., PAN, L., STAHL, N., IP, N., KATO, A., and YANCOPOULOS, G. (1995). Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth. Cell 83:313-322.
12. DUPIN, E., and LE DOUARIN, N. M. (1995). Retinoic acid promotes the differentiation of adrenergic cells and melanocytes in quail neural crest cultures. Dev. Biol. 168:529-548.
13. ECKENSTEIN, F. P., ESCH, F., HOLBERT, T., BLACHER, R. W., and NISHI, R. (1990). Purification and characterization of a trophic factor for embryonic peripheral neurons: comparison with fibroblast growth factors. Neuron 4:623-631.
14. FANN, M. J., and PATTERSON, P. H. (1994). Neuropoietic cytokines and activin-a differentially regulate the phenotype of cultured sympathetic neurons. Proc. Natl. Acad. Sci. USA 91:43-47.
15. GEARING, D. P., COMEAU, M. R., FRIEND, D. J., GIMPEL, S. D., THUT, C. J., MCGOURTY, J., BRASHER, K. K., KING, J. A., GILLIS, S., MOSLEY, B., ZIEGLER, S. F., and COSMAN, D. (1992). The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor. Science 255:1434-1437.
16. GEARING, D. P., ZIEGLER, S. F., COMEAU, M. R., FRIEND, D., THOMA, B., COSMAN, D., PARK, L., and MOSLEY, B. (1994). Proliferative responses and binding properties of hematopoietic cells transfected with low-affinity receptors for leukemia inhibitory factor, oncostatin-m, and ciliary neurotrophic factor. Proc. Natl. Acad. Sci. USA 91:1119-1123.
17. HALVORSEN, S. W., and BERG, D. K. (1986). Identification of a nicotinic acetylcholine receptor on neurons using an α-neurotoxin that blocks receptor function. J. Neurosci. 6:3405-3412.
18. HALVORSEN, S. W., JIANG, N., and MALEK, R. (1995). Regulation of nicotinic acetylcholine receptors on human neuroblastoma cells during differentiation. Biochem. Pharmacol. 50:1655-1661.
19. HALVORSEN, S. W., MALEK, R., WANG, X., and JIANG, N. (1996). Ciliary neurotrophic factor regulates nicotinic acetylcholine receptors on human neuroblastoma cells. Neuropharmacology 35:257-265.
20. HEIKKILÄ, J., AKERLIND, G., and AKERMAN, K. (1989). Protein kinase C activation and down-regulation in relation to phorbol ester-induced differentiation of SHSY5Y human neuroblastoma cells. J. Cell. Physiol. 140:593-600.
21. HEIKKILÄ, J., JALAVA, A., and ERIKSSON, K. (1993). The selective protein kinase C inhibitor GF 109203X inhibits phorbol ester-induced morphological and functional differentiation of SH-SY5Y human neuroblastoma cells. Biochem. Biophys. Res. Commun. 197:1185-1193.
22. HELGREN, M., SQUINTO, S., DAVIS, H., PARRY, D., BOULTON, T., HECK, C., ZHU, Y., YANCOPOULOS, G., and DISTEFANO, P. (1994). Trophic effect of ciliary neurotrophic factor on denervated skeletal muscle. Cell 76:493-504.
23. HIBI, M., MURAKAMI, M., SAITO, M., HIRANO, T., TAGA, T., and KJSHIMOTO, T. (1990). Molecular cloning and expression of an IL-6 signal transducer, gp130. Cell 63:1149-1157.
24. HILTON, D. J., HILTON, A. A., RAICEVIC, A., RAKAR, S., HARRISONSMITH, M., GOUGH, N. M., BEGLEY, C. G., METCALF, D., NICOLA, N. A., and WILLSON, T. A. (1994). Cloning of a murine IL-11 receptor alpha-chain - requirement for gp130 for high affinity binding and signal transduction. EMBO 13:4765-4775.
25. HUBER, J., DITTRICH, F., and PHELAN, P. (1993). Characterization of high-affinity and low-affinity receptors for ciliary neurotrophic factor. Eur. J. Biochem. 218:1031-1039.
26. IHLE, J. N. (1996). STATs: signal transducers and activators of transcription. Cell 84:331-334.
27. IP, F. C. F., Fu, A. K. Y., TSIM, K. W. K., and IP, N. Y. (1995). Cloning of the a component of the chick ciliary neurotrophic factor receptor - developmental expression and down-regulation in denervated skeletal muscle. J. Neurochem. 65:2393-2400.
28. IP, N. Y., MCCLAIN, J., BARREZUETA, N., ALDRICH, T., PAN, L., LI, Y., WIEGAND, S., FRIEDMAN, B., DAVIS, S., and YANCOPOULOS, G. (1993). The α component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development. Neuron 10:89-102.
29. IP, N. Y., NYE, S., BOULTON, T., DAVIS, S., TAGA, T., LI, Y., BIRREN, S., YASUKAWA, K., KISHIMOTO, T., ANDERSON, D., STAHL, N., and YANCOPOULOS, G. (1992). CNTF and LIF act on neuronal cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp130. Cell 69:1121-1132.
30. JALAVA, A., HEIKKILÄ, J., LINTUNEN, M., ÅKERMAN, K., and PÅHLMAN, S. (1992). Staurosporine induces a neuronal phenotype in SH-SY5Y human neuroblastoma cells that resembles that induced by the phorbol ester 12-O-tetradecanoyl phorbol-13 acetate (TPA). FEBS Lett 300:114-118.
31. JOHNSON, R. M., MCNEELEY, P., DEMOOR, K., STEWART, G., GLAESER, B., and PITCHFORD, S. (1994). Recombinant human ciliary neurotrophic factor stimulates the metabolic activity of SH-SY5Y cells as measured by a microphysiometer. Brain Res. 646:327-331.
32. KAPLAN, D. R., MATSUMOTO, K., LUCARELLI, E., and THIELE, C. J. (1993). Induction of TrkB by retinoic acid mediates biologic responsiveness to BDNF and differentiation of human neuroblastoma cells. Neuron 11:321-331.
33. KINGSTON, R. E., CHOMCZYNSKI, P., and SACCHI, N. (1991). Guanidinium methods for total RNA preparation. In: Current Protocols in Molecular Biology, F. A. Ausubel, R. Brent, R. Kingston, J. Moore, J. Seidman, J. Smith, and K. Stauhl, Eds. John Wiley and Sons, New York, pp. 4.2.1-4.2.6.
34. KISHIMOTO, T., AKIRA, S., and TAGA, T. (1992). Interleukin-6 and its receptor: a paradigm for cytokines. Science 258:593-597.
35. KOSHLUKOVA, S., FINN, T. P., NISHI, R., and HALVORSEN, S. W. (1996). Identification of functional receptors for ciliary neurotrophic factor on chick ciliary ganglion neurons. Neuroscience 72:821-832.
36. LANDIS, S. C., and KEEFE, D. (1983). Evidence for neuronal plasticity in vivo: developmental changes in the properties of cholinergic sympathetic neurons. Dev. Biol. 98:349-372.
37. LELI, U., PARKER, P., and SHEA, T. (1992). Intracellular delivery of protein kinase C-α or -ε isoform-specific antibodies promotes acquisition of a morphologically differentiated phenotype in neuroblastoma cells. FEBS Lett. 297:91-94.
38. LELI, U., SHEA, T., CATALOG, A., HAUSER, G., GRYNSPAN, F., BEERMAN, M., LIEPKALNS, V., NIXON, R., and PARKER P. (1993). Differential expression and subcellular localization of protein kinase C α, β, δ, and ε isoforms in SH-SY5Y neuroblastoma cells: modifications during differentiation. J. Neurochem. 60:289-298.
39. LESSER, S., and Lo, D. (1995). Regulation of voltage-gated ion channels by NGF and ciliary neurotrophic factor in SK-n-SH neuroblastoma cells. J. Neurosci. 15:253-261.
40. LOTAN, R., and CLIFFORD, J. L. (1991). Nuclear receptors for retinoids: mediators of retinoid effects on normal and malignant cells. Biomed. Pharmacother. 45:145-156.
41. LOVAT, P., PEARSON, A., MALCOLM, A., and REDFERN, C. P. F. (1993). Retinoic acid expression during the in vitro differentiation of human neuroblastoma. Neurosci. Lett. 162:109-113.
42. MACLENNAN, A. J., GASKIN, A. A., VINSON, E. N., and MARTINEZ, L. C. (1996). Ciliary neurotrophic factor receptor α mRNA in NB41A3 neuroblastoma cells: regulation by cAMP. Eur. J. Pharmacol. 295:103-108.
43. MADEN, M., ONG, D., SUMMERBELL, D., CHYTIL, F., and HIRST, E. (1989). Cellular retinoic acid-binding protein and the role of retinoic acid in development of the chick embryo. Dev. Biol. 135:124-132.
44. MALEK, R., and HALVORSEN, S. W. (1995). Regulation of ciliary neurotrophic factor receptors on differentiating neuroblastoma cells. Soc. Neurosci. Abstr. 21:1060.
45. MARTINY-BARON, G., KAZANIETZ, M., MISCHAK, H., BLUMBERG, P., KOCHS, G., HUG, H., MARME, D., and SCHACHTELE, C. (1993). Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö6976. J. Biol. Chem. 268:9194-9197.
46. MASIAKOWSKI, P., LIU, H., RADZIEJEWSKI, C., LOTTSPEICH, F., OBERTHUER, W., WONG, V., LINDSAY, R., FURTH, M., and PANAYOTATOS, N. (1991). Recombinant human and rat ciliary neurotrophic factors. J. Neurochem. 57:1003-1012.
47. PÅHLMAN, S., ODELSTAD, L., LARSSON, E., GROTTE, G., and NILSSON, K. (1981). Phenotypic changes of human neuroblastoma cells in culture induced by 12-O-tetradecanoyl-phorbol-13-acetate. Int. J. Cancer 28:583-589.
48. PÅHLMAN, S., RUUSALA, A.-I., ABRAHAMSSON, L., MATTSSON, M., and ESSCHER, T. (1984). Retinoic acid-induced differentiation of cultured human neuroblastoma cells: a comparison with phorbol-ester-induced differentiation. Cell Diff. 14:135-144.
49. PÅHLMAN, S., RUUSALA, A.-I., ABRAHAMSSON, L., ODELSTAD, L., and NILSSON, K. (1983). Kinetics and concentration effects of TPA-induced differentiation of cultured human neuroblastoma cells. Cell Diff. 12:165-170.
50. PANAYOTATOS, N., RADZIEJEWSKI, E., ACHESON. A., PEARSALL, D., THADANI, A., and WONG, V. (1993). Exchange of a single amino acid interconverts the specific activity and gel mobility of human and rat ciliary neurotrophic factors. J. Biol. Chem. 258:19000-19003.
51. PENNICA, D., KING, K., SHAW, K., LUIS, E., RULLAMAS, J., LUOH, S.-M., DARBONNE, W., KNUTZON, D., YEN, R., CHIEN, K., BAKER, J., and WOOD, W. I. (1995). Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy. Proc. Natl Acad. Sci. USA 92:1142-1146.
52. PLUM, L. A., and CLAGETT-DAME, M. (1995). 9-cis-Retinoic acid selectively activates the cellular retinoic acid binding protein-II gene in human neuroblastoma cells. Arch. Biochem. Biophys. 319:457-463.
53. RICHARDSON, P. M. (1994). Ciliary neurotrophic factor: a review. Pharmacol. Ther. 63:187-198.
54. Ross, A. C. (1993). Overview of retinoid metabolism. J. Nutrition 123:346-350.
55. ROWE, A., EAGER, N., and BRICKELL, P. (1991). A member of the RXR nuclear receptor family is expressed in neural-crest-derived cells of the developing chick peripheral nervous system. Development 111:771-778.
56. SAADET, S., SENDTNER, M., and ROHRER, H. (1989). Ciliary neurotrophic factor induces cholinergic differentiation of rat sympathetic neurons in culture. J. Cell Biol. 108:1807-1816.
57. SCHOTZINGER, R., YIN, X., and LANDIS, S. (1994). Target determination of neurotransmitter phenotype in sympathetic neurons. J. Neurobiol. 25:620-639.
58. STAHL, N., and YANCOPOULOS, G. (1993). The alphas, betas, and kinases of cytokine receptor complexes. Cell 74:587-590.
59. SUN, Y., and MAXWELL, G. D. (1994). Ciliary neurotrophic factor (CNTF) has a dose-dependent biphasic effect on the number of adrenergic cells which develop in avian trunk neural crest. Neurosci. Lett. 165:1-4.
60. THOMPSON, K. L., and ROSNER, M. R. (1989). Regulation of epidermal growth factor receptor gene expression by retinoic acid and epidermal growth factor. J. Biol. Chem. 264:3230-3234.
61. TOULLEC, D., PIANETTI, P., COSTE, H., BELLEVERGUE, P., GRAND-PERRET, T., AJAKANE, M., BAUDET, V., BOISSIN, P., BOURSIER, E., LORIOLLE, F., DUHAMEL, L., CHARON, D., and KIRILOVSKY, J. (1991). The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J. Biol. Chem. 266:15771-15781.
62. WANG, C., KELLY, J., BOWEN-POPE, D. F., and STILES, C. D. (1990). Retinoic acid promotes gene transcription of the platelet-derived growth factor receptor α-receptor gene. Mol. Cell. Biol. 10:6781-6784.
63. YANG, Y.-C. (1993). Interleukin 11: an overview. Stem Cells 11:474-486.
64. ZHANG, Q.-Y., HAMMERBERG, C., BALDASSARE, J. J., HENDERSON, P. A., BURNS, D., CESKA, M., VOORHEES, J. J., and FISHER, G. J. (1992). Retinoic acid and phorbol ester synergistically up-regulate IL-8 expression and specifically modulate protein kinase C-ε in human skin fibroblasts. J. Immunol 149:1402-1408.