메뉴 건너뛰기




Volumn 7, Issue 11, 1997, Pages 817-826

Janus kinases in interleukin-2-mediated signaling: JAK1 and JAK3 are differentially regulated by tyrosine phosphorylation

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; JANUS;

EID: 0031282551     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(06)00369-1     Document Type: Article
Times cited : (78)

References (51)
  • 1
    • 0000408006 scopus 로고    scopus 로고
    • Interleukin-2 and the interleukin-2 receptor complex
    • Edited by A. Thomson. London: Academic Press; in press
    • Gaffen SL, Goldsmith MA, Greene WC: Interleukin-2 and the interleukin-2 receptor complex. In The Cytokine Handbook. Edited by A. Thomson. London: Academic Press; 1997, in press.
    • (1997) The Cytokine Handbook
    • Gaffen, S.L.1    Goldsmith, M.A.2    Greene, W.C.3
  • 2
    • 0021707413 scopus 로고
    • Cloning, sequence and expression of human interleukin-2 receptor
    • Cosman D, Cerretti D, Larsen A, Park L, March C, Dower S, et al.: Cloning, sequence and expression of human interleukin-2 receptor. Nature 1984, 312:768-771.
    • (1984) Nature , vol.312 , pp. 768-771
    • Cosman, D.1    Cerretti, D.2    Larsen, A.3    Park, L.4    March, C.5    Dower, S.6
  • 6
    • 0028286628 scopus 로고
    • Cytoplasmic domains of the interleukin-2 receptor β and γ chains mediate the signal for T-cell proliferation
    • Nelson BH, Lord JD, Greenberg PD: Cytoplasmic domains of the interleukin-2 receptor β and γ chains mediate the signal for T-cell proliferation. Nature 1994, 369:333-336.
    • (1994) Nature , vol.369 , pp. 333-336
    • Nelson, B.H.1    Lord, J.D.2    Greenberg, P.D.3
  • 7
    • 0028286627 scopus 로고
    • Heterodimerization of the IL-2 receptor β- And γ-chain cytoplasmic domains is required for signaling
    • Nakamura Y, Russell SM, Mess SA, Friedmann M, Erdos M, Francois C, et al.: Heterodimerization of the IL-2 receptor β- and γ-chain cytoplasmic domains is required for signaling. Nature 1994, 369:330-333.
    • (1994) Nature , vol.369 , pp. 330-333
    • Nakamura, Y.1    Russell, S.M.2    Mess, S.A.3    Friedmann, M.4    Erdos, M.5    Francois, C.6
  • 8
    • 0025162844 scopus 로고
    • Structural design and molecular evolution of a cytokine receptor superfamily
    • Bazan JF: Structural design and molecular evolution of a cytokine receptor superfamily. Proc Natl Acad Sci USA 1990, 87:6934-6938.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6934-6938
    • Bazan, J.F.1
  • 10
    • 0028234529 scopus 로고
    • JAK-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell JE, Kerr IM, Stark GR: JAK-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994, 264:1415-1421.
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell, J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 11
    • 0028845212 scopus 로고
    • Cytokine receptor signaling
    • Ihle JN: Cytokine receptor signaling. Nature 1995, 377:591-594.
    • (1995) Nature , vol.377 , pp. 591-594
    • Ihle, J.N.1
  • 12
    • 0029069145 scopus 로고
    • Transcriptional responses to polypeptide ligands: The JAK-STAT pathway
    • Schindler C, Darnell JE: Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu Rev Biochem 1995, 64:621-651.
    • (1995) Annu Rev Biochem , vol.64 , pp. 621-651
    • Schindler, C.1    Darnell, J.E.2
  • 14
    • 0028029813 scopus 로고
    • Activation of JAK kinases and STAT proteins by interleukin-2 and Interferon alpha, but not the T-cell antigen receptor, in human T lymphocytes
    • Beadling C, Gischin D, Witthuhn BA, Ziemiecki A, Ihle JN, Kerr IM, et al.: Activation of JAK kinases and STAT proteins by interleukin-2 and Interferon alpha, but not the T-cell antigen receptor, in human T lymphocytes. EMBO J 1994, 13:5605-5615.
    • (1994) EMBO J , vol.13 , pp. 5605-5615
    • Beadling, C.1    Gischin, D.2    Witthuhn, B.A.3    Ziemiecki, A.4    Ihle, J.N.5    Kerr, I.M.6
  • 16
    • 0028819828 scopus 로고
    • Interleukin 2 activates STAT5 transcription factor (mammary gland factor) and specific gene expression in T lymphocytes
    • Gilmour KC, Pine R, Reich NC: Interleukin 2 activates STAT5 transcription factor (mammary gland factor) and specific gene expression in T lymphocytes. Proc Natl Acad Sci USA 1995, 92:10772-10776.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 10772-10776
    • Gilmour, K.C.1    Pine, R.2    Reich, N.C.3
  • 17
    • 0028964916 scopus 로고
    • Identification and purification of human STAT proteins activated in response to IL-2
    • Hou J, Schindler U, Henzel WJ, Wong SC, McKnight SL: Identification and purification of human STAT proteins activated in response to IL-2. Immunity 1995, 2:325-330.
    • (1995) Immunity , vol.2 , pp. 325-330
    • Hou, J.1    Schindler, U.2    Henzel, W.J.3    Wong, S.C.4    McKnight, S.L.5
  • 18
    • 0029046208 scopus 로고
    • Activation of STAT5 by interleukin 2 requires a carboxyl-terminal region of the interleukin-2 receptor β chain but is not essential for the proliferative signal transmission
    • Fujii H, Nakagawa Y, Schindler U, Kawahara A, Mori H, Gouilleux F, et al.: Activation of STAT5 by interleukin 2 requires a carboxyl-terminal region of the interleukin-2 receptor β chain but is not essential for the proliferative signal transmission. Proc Natl Acad Sci USA 1995, 92:5482-5486.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5482-5486
    • Fujii, H.1    Nakagawa, Y.2    Schindler, U.3    Kawahara, A.4    Mori, H.5    Gouilleux, F.6
  • 19
  • 20
    • 0028962572 scopus 로고
    • The role of shared receptor motifs and common STAT proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13 and IL-15
    • Lin J-X, Migone T-S, Tsang M, Friedmann M, Weatherbee JA, Zhou L, et al.: The role of shared receptor motifs and common STAT proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13 and IL-15. Immunity 1995, 2:331-339.
    • (1995) Immunity , vol.2 , pp. 331-339
    • Lin, J.-X.1    Migone, T.-S.2    Tsang, M.3    Friedmann, M.4    Weatherbee, J.A.5    Zhou, L.6
  • 23
    • 0028963550 scopus 로고
    • Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs
    • Mui AL-F, Wakao H, O'Farrell A-M, Harada N, Miyajima A: Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs. EMBO J 1995, 14:1166-1175.
    • (1995) EMBO J , vol.14 , pp. 1166-1175
    • Mui, A.L.-F.1    Wakao, H.2    O'Farrell, A.-M.3    Harada, N.4    Miyajima, A.5
  • 24
    • 0029813118 scopus 로고    scopus 로고
    • Distinct tyrosine residues within the interleukin-2 receptor β chain drive signal transduction specificity, redundancy, and diversity
    • Gaffen SL, Lai SY, Ha M, Liu X, Hennighausen L, Greene WC, et al.: Distinct tyrosine residues within the interleukin-2 receptor β chain drive signal transduction specificity, redundancy, and diversity. J Biol Chem 1996, 271:21381-21390.
    • (1996) J Biol Chem , vol.271 , pp. 21381-21390
    • Gaffen, S.L.1    Lai, S.Y.2    Ha, M.3    Liu, X.4    Hennighausen, L.5    Greene, W.C.6
  • 26
    • 0029081380 scopus 로고
    • Identification of a variable region within the cytoplasmic tail of the IL-2 receptor β chain that is required for growth signal transduction
    • Liu KD, Lai SY, Goldsmith MA, Greene WC: Identification of a variable region within the cytoplasmic tail of the IL-2 receptor β chain that is required for growth signal transduction. J Biol Chem 1995, 270:22176-22181.
    • (1995) J Biol Chem , vol.270 , pp. 22176-22181
    • Liu, K.D.1    Lai, S.Y.2    Goldsmith, M.A.3    Greene, W.C.4
  • 27
    • 0028889726 scopus 로고
    • Activation of JAK3, but not JAK1, is critical for IL-2-induced proliferation and STAT5 recruitment by a COOH-terminal region of the IL-2 receptor β-chain
    • Kirken RA, Rui H, Malabarba MG, Howard OM, Kawamura M, O'Shea JJ, et al.: Activation of JAK3, but not JAK1, is critical for IL-2-induced proliferation and STAT5 recruitment by a COOH-terminal region of the IL-2 receptor β-chain. Cytokine 1995, 7:689-700.
    • (1995) Cytokine , vol.7 , pp. 689-700
    • Kirken, R.A.1    Rui, H.2    Malabarba, M.G.3    Howard, O.M.4    Kawamura, M.5    O'Shea, J.J.6
  • 28
    • 0030062769 scopus 로고    scopus 로고
    • Kinase-negative mutants of JAK1 can sustain interferon-γ-inducible gene expression but not an antiviral state
    • Briscoe J, Rogers NC, Witthuhn BA, Watling D, Harpur AG, Wilks AF, et al.: Kinase-negative mutants of JAK1 can sustain interferon-γ-inducible gene expression but not an antiviral state. EMBO J 1996, 15:799-809.
    • (1996) EMBO J , vol.15 , pp. 799-809
    • Briscoe, J.1    Rogers, N.C.2    Witthuhn, B.A.3    Watling, D.4    Harpur, A.G.5    Wilks, A.F.6
  • 29
    • 0028271690 scopus 로고
    • Protein kinase regulation: Insights from crystal structure analysis
    • Morgan DO, De Bondt HL: Protein kinase regulation: insights from crystal structure analysis. Curr Opin Cell Biol 1994, 6:239-246.
    • (1994) Curr Opin Cell Biol , vol.6 , pp. 239-246
    • Morgan, D.O.1    De Bondt, H.L.2
  • 30
    • 0029993727 scopus 로고    scopus 로고
    • Active and inactive protein kinases: Structural basis for regulation
    • Johnson LN, Noble MEM, Owen DJ: Active and inactive protein kinases: structural basis for regulation. Cell 1996, 85:149-158.
    • (1996) Cell , vol.85 , pp. 149-158
    • Johnson, L.N.1    Noble, M.E.M.2    Owen, D.J.3
  • 31
    • 0023885305 scopus 로고
    • The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains
    • Hanks SK, Quinn AM, Hunter T: The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science 1988, 241:42-52.
    • (1988) Science , vol.241 , pp. 42-52
    • Hanks, S.K.1    Quinn, A.M.2    Hunter, T.3
  • 32
    • 0030953469 scopus 로고    scopus 로고
    • Activation of JAK2 catalytic activity requires phosphorylation of Y1007 in the kinase activation Loop
    • Feng J, Witthuhn BA, Matsuda T, Kohlhuber F, Kerr IM, Ihle JN: Activation of JAK2 catalytic activity requires phosphorylation of Y1007 in the kinase activation Loop. Mol Cell Biol 1997, 17:2497-2501.
    • (1997) Mol Cell Biol , vol.17 , pp. 2497-2501
    • Feng, J.1    Witthuhn, B.A.2    Matsuda, T.3    Kohlhuber, F.4    Kerr, I.M.5    Ihle, J.N.6
  • 33
    • 0029786754 scopus 로고    scopus 로고
    • Interferon-α-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase
    • Gauzzi MC, Velasquez L, McKendry R, Mogensen KE, Fellous M, Pellegrini S: Interferon-α-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase. J Biol Chem 1996, 271:20494-20500.
    • (1996) J Biol Chem , vol.271 , pp. 20494-20500
    • Gauzzi, M.C.1    Velasquez, L.2    McKendry, R.3    Mogensen, K.E.4    Fellous, M.5    Pellegrini, S.6
  • 34
    • 0027993605 scopus 로고
    • Prolactin induces phosphorylation of Tyr694 of STAT5 (MGF), a prerequisite for DNA binding and induction of transcription
    • Gouilleux F, Wakao H, Mundt M, Groner B: Prolactin induces phosphorylation of Tyr694 of STAT5 (MGF), a prerequisite for DNA binding and induction of transcription. EMBO J 1994, 13:4361-4369.
    • (1994) EMBO J , vol.13 , pp. 4361-4369
    • Gouilleux, F.1    Wakao, H.2    Mundt, M.3    Groner, B.4
  • 35
    • 0027742729 scopus 로고
    • Interferon-induced nuclear signalling by JAK protein tyrosine kinases
    • Silvennoinen O, Ihle JN, Schlessinger J, Levy DE: Interferon-induced nuclear signalling by JAK protein tyrosine kinases. Nature 1993, 366:583-585.
    • (1993) Nature , vol.366 , pp. 583-585
    • Silvennoinen, O.1    Ihle, J.N.2    Schlessinger, J.3    Levy, D.E.4
  • 36
    • 0029133520 scopus 로고
    • Phosphorylation and activation of the DNA binding activity of purified STAT1 by the Janus protein-kinases and the epidermal growth factor receptor
    • Quelle FW, Thierfelder W, Witthuhn BA, Tang B, Cohen S, Ihle JN: Phosphorylation and activation of the DNA binding activity of purified STAT1 by the Janus protein-kinases and the epidermal growth factor receptor. J Biol Chem 1995, 270:20775-20780.
    • (1995) J Biol Chem , vol.270 , pp. 20775-20780
    • Quelle, F.W.1    Thierfelder, W.2    Witthuhn, B.A.3    Tang, B.4    Cohen, S.5    Ihle, J.N.6
  • 37
    • 0031009816 scopus 로고    scopus 로고
    • The amino terminus of JAK3 is necessary and sufficient for binding to the common γ chain and confers the ability to transmit interleukin 2-mediated signals
    • Chen M, Cheng A, Chen Y-Q, Hymel A, Hanson EP, Kimmel L, et al.: The amino terminus of JAK3 is necessary and sufficient for binding to the common γ chain and confers the ability to transmit interleukin 2-mediated signals. Proc Natl Acad Sci USA 1997, 94:6910-6915.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 6910-6915
    • Chen, M.1    Cheng, A.2    Chen, Y.-Q.3    Hymel, A.4    Hanson, E.P.5    Kimmel, L.6
  • 38
    • 0028957771 scopus 로고
    • The conserved box 1 motif of cytokine receptors is required for association with JAK kinases
    • Tanner JW, Chen W, Young RL, Longmore G, Shaw AS: The conserved box 1 motif of cytokine receptors is required for association with JAK kinases. J Biol Chem 1995, 270:6523-6530.
    • (1995) J Biol Chem , vol.270 , pp. 6523-6530
    • Tanner, J.W.1    Chen, W.2    Young, R.L.3    Longmore, G.4    Shaw, A.S.5
  • 39
    • 0029024882 scopus 로고
    • Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor
    • Frank SJ, Yi W, Zhao Y, Goldsmith JF, Gilliland G, Jiang J, et al.: Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor. J Biol Chem 1995, 270:14776-14785.
    • (1995) J Biol Chem , vol.270 , pp. 14776-14785
    • Frank, S.J.1    Yi, W.2    Zhao, Y.3    Goldsmith, J.F.4    Gilliland, G.5    Jiang, J.6
  • 40
    • 0028835347 scopus 로고
    • Distinct domains of the protein tyrosine kinase tyk2 required for binding of interferon-alpha/ beta and for signal transduction
    • Velazquez L, Mogensen KE, Barbieri G, Fellous M, Uze G, Pellegrini S: Distinct domains of the protein tyrosine kinase tyk2 required for binding of interferon-alpha/ beta and for signal transduction. J Biol Chem 1995, 270:3327-3334.
    • (1995) J Biol Chem , vol.270 , pp. 3327-3334
    • Velazquez, L.1    Mogensen, K.E.2    Barbieri, G.3    Fellous, M.4    Uze, G.5    Pellegrini, S.6
  • 41
    • 0027494653 scopus 로고
    • The protein tyrosine kinase JAK1 complements defects in interferon-alpha/ beta and -gamma signal transduction
    • Müller M, Briscoe J, Laxton C, Guschin D, Ziemiecki A, Silvennoinen O, et al.: The protein tyrosine kinase JAK1 complements defects in interferon-alpha/ beta and -gamma signal transduction. Nature 1993, 366:129-166.
    • (1993) Nature , vol.366 , pp. 129-166
    • Müller, M.1    Briscoe, J.2    Laxton, C.3    Guschin, D.4    Ziemiecki, A.5    Silvennoinen, O.6
  • 42
    • 0030447148 scopus 로고    scopus 로고
    • In vitro activation of STAT3 by epidermal growth factor receptor kinase
    • Park OK, Schaefer TS, Nathans D: In vitro activation of STAT3 by epidermal growth factor receptor kinase. Proc Natl Acad Sci USA 1996, 93:13704-13708.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13704-13708
    • Park, O.K.1    Schaefer, T.S.2    Nathans, D.3
  • 43
    • 0030038840 scopus 로고    scopus 로고
    • Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases
    • Rawlings DJ, Scharenberg AM, Park H, Wahl MI, Lin S, Kato RM, et al.: Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases. Science 1996, 271:822-825.
    • (1996) Science , vol.271 , pp. 822-825
    • Rawlings, D.J.1    Scharenberg, A.M.2    Park, H.3    Wahl, M.I.4    Lin, S.5    Kato, R.M.6
  • 44
    • 0028582185 scopus 로고
    • Crystal structure of the tyrosine kinase domain of the human insulin receptor
    • Hubbard SR, Wei L, Ellis L, Hendrickson WA: Crystal structure of the tyrosine kinase domain of the human insulin receptor. Nature 1994, 372:746-754.
    • (1994) Nature , vol.372 , pp. 746-754
    • Hubbard, S.R.1    Wei, L.2    Ellis, L.3    Hendrickson, W.A.4
  • 45
    • 0030598848 scopus 로고    scopus 로고
    • Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism
    • Mohammadi M, Schlessinger J, Hubbard SR: Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism. Cell 1996, 86:577-587.
    • (1996) Cell , vol.86 , pp. 577-587
    • Mohammadi, M.1    Schlessinger, J.2    Hubbard, S.R.3
  • 46
    • 0028332867 scopus 로고
    • The cytoplasmic domain of the IL-2 receptor β chain contains both unique and functionally redundant signal transduction elements
    • Goldsmith MA, Xu W, Amaral MC, Kuczek ES, Greene WC: The cytoplasmic domain of the IL-2 receptor β chain contains both unique and functionally redundant signal transduction elements. J Biol Chem 1994, 269:14698-14704.
    • (1994) J Biol Chem , vol.269 , pp. 14698-14704
    • Goldsmith, M.A.1    Xu, W.2    Amaral, M.C.3    Kuczek, E.S.4    Greene, W.C.5
  • 49
    • 0024380087 scopus 로고
    • Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells
    • Schreiber E, Matthias P, Muller MM, Schaffner W: Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res 1989, 17:6419-6420.
    • (1989) Nucleic Acids Res , vol.17 , pp. 6419-6420
    • Schreiber, E.1    Matthias, P.2    Muller, M.M.3    Schaffner, W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.