메뉴 건너뛰기




Volumn 4, Issue 6, 2009, Pages

Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes

Author keywords

[No Author keywords available]

Indexed keywords

DELTA LIKE 1 PROTEIN; LIGAND; NOTCH RECEPTOR; UNCLASSIFIED DRUG; DLK1 PROTEIN, MOUSE; SIGNAL PEPTIDE;

EID: 67650665279     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006054     Document Type: Article
Times cited : (16)

References (90)
  • 1
    • 5444247778 scopus 로고    scopus 로고
    • Notch signaling: The demise of elegant simplicity
    • Kadesch T (2004) Notch signaling: the demise of elegant simplicity. Curr Opin Genet Dev 14: 506-512.
    • (2004) Curr Opin Genet Dev , vol.14 , pp. 506-512
    • Kadesch, T.1
  • 2
    • 33947241465 scopus 로고    scopus 로고
    • SnapShot: Notch signaling pathway
    • Ilagan MX, Kopan R (2007) SnapShot: notch signaling pathway. Cell 128: 1246.
    • (2007) Cell , vol.128 , pp. 1246
    • Ilagan, M.X.1    Kopan, R.2
  • 3
    • 34447509872 scopus 로고    scopus 로고
    • Notch signaling - constantly on the move
    • Nichols JT, Miyamoto A, Weinmaster G (2007) Notch signaling - constantly on the move. Traffic 8: 959-969.
    • (2007) Traffic , vol.8 , pp. 959-969
    • Nichols, J.T.1    Miyamoto, A.2    Weinmaster, G.3
  • 5
    • 37449010541 scopus 로고    scopus 로고
    • The multifaceted role of Notch in cardiac development and disease
    • High FA, Epstein JA (2008) The multifaceted role of Notch in cardiac development and disease. Nat Rev Genet 9: 49-61.
    • (2008) Nat Rev Genet , vol.9 , pp. 49-61
    • High, F.A.1    Epstein, J.A.2
  • 6
    • 34548164780 scopus 로고    scopus 로고
    • Notch signaling in vascular development and physiology
    • Gridley T (2007) Notch signaling in vascular development and physiology. Development 134: 2709-2718.
    • (2007) Development , vol.134 , pp. 2709-2718
    • Gridley, T.1
  • 7
    • 34250209506 scopus 로고    scopus 로고
    • Notch signaling in blood vessels: Who is talking to whom about what?
    • Hofmann JJ, Iruela-Arispe ML (2007) Notch signaling in blood vessels: who is talking to whom about what? Circ Res 100: 1556-1568.
    • (2007) Circ Res , vol.100 , pp. 1556-1568
    • Hofmann, J.J.1    Iruela-Arispe, M.L.2
  • 8
    • 1842480002 scopus 로고    scopus 로고
    • Expression of Notch-1 and its ligand Jagged-1 in rat liver during liver regeneration
    • Kohler C, Bell AW, Bowen WC, Monga SP, Fleig W, et al. (2004) Expression of Notch-1 and its ligand Jagged-1 in rat liver during liver regeneration. Hepatology 39: 1056-1065.
    • (2004) Hepatology , vol.39 , pp. 1056-1065
    • Kohler, C.1    Bell, A.W.2    Bowen, W.C.3    Monga, S.P.4    Fleig, W.5
  • 9
    • 33748448512 scopus 로고    scopus 로고
    • Manipulation of endogenous neural stem cells following ischemic brain injury
    • Leker RR (2006) Manipulation of endogenous neural stem cells following ischemic brain injury. Pathophysiol Haemost Thromb 35: 58-62.
    • (2006) Pathophysiol Haemost Thromb , vol.35 , pp. 58-62
    • Leker, R.R.1
  • 10
    • 0036014932 scopus 로고    scopus 로고
    • Transforming growth factor-beta induces renal epithelial jagged-1 expression in fibrotic disease
    • Morrissey J, Guo G, Moridaira K, Fitzgerald M, McCracken R, et al. (2002) Transforming growth factor-beta induces renal epithelial jagged-1 expression in fibrotic disease. J Am Soc Nephrol 13: 1499-1508.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1499-1508
    • Morrissey, J.1    Guo, G.2    Moridaira, K.3    Fitzgerald, M.4    McCracken, R.5
  • 11
    • 43749117539 scopus 로고    scopus 로고
    • Expression and function of the Delta-1/Notch-2/Hes-1 pathway during experimental acute kidney injury
    • Kobayashi T, Terada Y, Kuwana H, Tanaka H, Okado T, et al. (2008) Expression and function of the Delta-1/Notch-2/Hes-1 pathway during experimental acute kidney injury. Kidney Int 73: 1240-1250.
    • (2008) Kidney Int , vol.73 , pp. 1240-1250
    • Kobayashi, T.1    Terada, Y.2    Kuwana, H.3    Tanaka, H.4    Okado, T.5
  • 13
    • 2342578680 scopus 로고    scopus 로고
    • Suppressor screen in Mpl-/- mice: C-Myb mutation causes supraphysiological production of platelets in the absence of thrombopoietin signaling
    • Carpinelli MR, Hilton DJ, Metcalf D, Antonchuk JL, Hyland CD, et al. (2004) Suppressor screen in Mpl-/- mice: c-Myb mutation causes supraphysiological production of platelets in the absence of thrombopoietin signaling. Proc Natl Acad Sci U S A 101: 6553-6558.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 6553-6558
    • Carpinelli, M.R.1    Hilton, D.J.2    Metcalf, D.3    Antonchuk, J.L.4    Hyland, C.D.5
  • 14
    • 34249010460 scopus 로고    scopus 로고
    • A genetic screen for modifiers of the delta1-dependent notch signaling function in the mouse
    • Rubio-Aliaga I, Soewarto D, Wagner S, Klaften M, Fuchs H, et al. (2007) A genetic screen for modifiers of the delta1-dependent notch signaling function in the mouse. Genetics 175: 1451-1463.
    • (2007) Genetics , vol.175 , pp. 1451-1463
    • Rubio-Aliaga, I.1    Soewarto, D.2    Wagner, S.3    Klaften, M.4    Fuchs, H.5
  • 15
    • 0030976083 scopus 로고    scopus 로고
    • Maintenance of somite borders in mice requires the Delta homologue DII1
    • Hrabe de Angelis M, McIntyre J 2nd, Gossler A (1997) Maintenance of somite borders in mice requires the Delta homologue DII1. Nature 386: 717-721.
    • (1997) Nature , vol.386 , pp. 717-721
    • Hrabe de Angelis, M.1    McIntyre 2nd, J.2    Gossler, A.3
  • 16
    • 0032897080 scopus 로고    scopus 로고
    • Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1
    • Xue Y, Gao X, Lindsell CE, Norton CR, Chang B, et al. (1999) Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1. Hum Mol Genet 8: 723-730.
    • (1999) Hum Mol Genet , vol.8 , pp. 723-730
    • Xue, Y.1    Gao, X.2    Lindsell, C.E.3    Norton, C.R.4    Chang, B.5
  • 18
    • 0030273134 scopus 로고    scopus 로고
    • Expression of the Notch 3 intracellular domain in mouse central nervous system progenitor cells is lethal and leads to disturbed neural tube development
    • Lardelli M, Williams R, Mitsiadis T, Lendahl U (1996) Expression of the Notch 3 intracellular domain in mouse central nervous system progenitor cells is lethal and leads to disturbed neural tube development. Mech Dev 59: 177-190.
    • (1996) Mech Dev , vol.59 , pp. 177-190
    • Lardelli, M.1    Williams, R.2    Mitsiadis, T.3    Lendahl, U.4
  • 19
    • 0032054238 scopus 로고    scopus 로고
    • Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice
    • Jiang R, Lan Y, Chapman HD, Shawber C, Norton CR, et al. (1998) Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice. Genes Dev 12: 1046-1057.
    • (1998) Genes Dev , vol.12 , pp. 1046-1057
    • Jiang, R.1    Lan, Y.2    Chapman, H.D.3    Shawber, C.4    Norton, C.R.5
  • 20
    • 21444455843 scopus 로고    scopus 로고
    • Introducing the German Mouse Clinic: Open access platform for standardized phenotyping
    • Gailus-Durner V, Fuchs H, Becker L, Bolle I, Brielmeier M, et al. (2005) Introducing the German Mouse Clinic: open access platform for standardized phenotyping. Nat Methods 2: 403-404.
    • (2005) Nat Methods , vol.2 , pp. 403-404
    • Gailus-Durner, V.1    Fuchs, H.2    Becker, L.3    Bolle, I.4    Brielmeier, M.5
  • 21
    • 27644501458 scopus 로고    scopus 로고
    • EMPReSS: Standardized phenotype screens for functional annotation of the mouse genome
    • Brown SD, Chambon P, Hrabé de Angelis M (2005) EMPReSS: standardized phenotype screens for functional annotation of the mouse genome. Nat Genet 37: 1155.
    • (2005) Nat Genet , vol.37 , pp. 1155
    • Brown, S.D.1    Chambon, P.2    Hrabé de Angelis, M.3
  • 22
    • 51749111621 scopus 로고    scopus 로고
    • Phenotypic characterization of mouse models for bone-related diseases in the German Mouse Clinic
    • Fuchs H, Lisse T, Hans W, Abe K, Thiele F, et al. (2008) Phenotypic characterization of mouse models for bone-related diseases in the German Mouse Clinic. J Musculoskelet Neuronal Interact 8: 13-14.
    • (2008) J Musculoskelet Neuronal Interact , vol.8 , pp. 13-14
    • Fuchs, H.1    Lisse, T.2    Hans, W.3    Abe, K.4    Thiele, F.5
  • 23
    • 35048883475 scopus 로고    scopus 로고
    • Genetic background modifies inner ear and eye phenotypes of jag1 heterozygous mice
    • Kiernan AE, Li R, Hawes NL, Churchill GA, Gridley T (2007) Genetic background modifies inner ear and eye phenotypes of jag1 heterozygous mice. Genetics 177: 307-311.
    • (2007) Genetics , vol.177 , pp. 307-311
    • Kiernan, A.E.1    Li, R.2    Hawes, N.L.3    Churchill, G.A.4    Gridley, T.5
  • 24
    • 41549157255 scopus 로고    scopus 로고
    • Systematic gene expression profiling of mouse model series reveals coexpressed genes
    • Horsch M, Schadler S, Gailus-Durner V, Fuchs H, Meyer H, et al. (2008) Systematic gene expression profiling of mouse model series reveals coexpressed genes. Proteomics 8: 1248-1256.
    • (2008) Proteomics , vol.8 , pp. 1248-1256
    • Horsch, M.1    Schadler, S.2    Gailus-Durner, V.3    Fuchs, H.4    Meyer, H.5
  • 25
    • 0037386594 scopus 로고    scopus 로고
    • Delta-Notch signaling controls the generation of neurons/glia from neural stem cells in a stepwise process
    • Grandbarbe L, Bouissac J, Rand M, Hrabe de Angelis M, Artavanis-Tsakonas S, et al. (2003) Delta-Notch signaling controls the generation of neurons/glia from neural stem cells in a stepwise process. Development 130: 1391-1402.
    • (2003) Development , vol.130 , pp. 1391-1402
    • Grandbarbe, L.1    Bouissac, J.2    Rand, M.3    Hrabe de Angelis, M.4    Artavanis-Tsakonas, S.5
  • 26
    • 38449106709 scopus 로고    scopus 로고
    • The thymus as an inductive site for T lymphopoiesis
    • Ciofani M, Zuniga-Pflucker JC (2007) The thymus as an inductive site for T lymphopoiesis. Annu Rev Cell Dev Biol 23: 463-493.
    • (2007) Annu Rev Cell Dev Biol , vol.23 , pp. 463-493
    • Ciofani, M.1    Zuniga-Pflucker, J.C.2
  • 27
    • 34247224342 scopus 로고    scopus 로고
    • Regulation of lymphocyte development by Notch signaling
    • Tanigaki K, Honjo T (2007) Regulation of lymphocyte development by Notch signaling. Nat Immunol 8: 451-456.
    • (2007) Nat Immunol , vol.8 , pp. 451-456
    • Tanigaki, K.1    Honjo, T.2
  • 28
    • 29244451407 scopus 로고    scopus 로고
    • Identification of Dll1 (Delta1) target genes during mouse embryogenesis using differential expression profiling
    • Machka C, Kersten M, Zobawa M, Harder A, Horsch M, et al. (2005) Identification of Dll1 (Delta1) target genes during mouse embryogenesis using differential expression profiling. Gene Expr Patterns 6: 94-101.
    • (2005) Gene Expr Patterns , vol.6 , pp. 94-101
    • Machka, C.1    Kersten, M.2    Zobawa, M.3    Harder, A.4    Horsch, M.5
  • 29
    • 27644512860 scopus 로고    scopus 로고
    • Efficient and fast targeted production of murine models based on ENU mutagenesis
    • Augustin M, Sedlmeier R, Peters T, Huffstadt U, Kochmann E, et al. (2005) Efficient and fast targeted production of murine models based on ENU mutagenesis. Mamm Genome 16: 405-413.
    • (2005) Mamm Genome , vol.16 , pp. 405-413
    • Augustin, M.1    Sedlmeier, R.2    Peters, T.3    Huffstadt, U.4    Kochmann, E.5
  • 30
    • 50549096379 scopus 로고    scopus 로고
    • Genetic influence on immune phenotype revealed strain-specific variations in peripheral blood lineages
    • Petkova SB, Yuan R, Tsaih SW, Schott W, Roopenian DC, et al. (2008) Genetic influence on immune phenotype revealed strain-specific variations in peripheral blood lineages. Physiol Genomics 34: 304-314.
    • (2008) Physiol Genomics , vol.34 , pp. 304-314
    • Petkova, S.B.1    Yuan, R.2    Tsaih, S.W.3    Schott, W.4    Roopenian, D.C.5
  • 31
    • 2942659675 scopus 로고    scopus 로고
    • Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo
    • Hozumi K, Negishi N, Suzuki D, Abe N, Sotomaru Y, et al. (2004) Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo. Nat Immunol 5: 638-644.
    • (2004) Nat Immunol , vol.5 , pp. 638-644
    • Hozumi, K.1    Negishi, N.2    Suzuki, D.3    Abe, N.4    Sotomaru, Y.5
  • 32
    • 14244260068 scopus 로고    scopus 로고
    • DNA methylation and the expanding epigenetics of T cell lineage commitment
    • Wilson CB, Makar KW, Shnyreva M, Fitzpatrick DR (2005) DNA methylation and the expanding epigenetics of T cell lineage commitment. Semin Immunol 17: 105-119.
    • (2005) Semin Immunol , vol.17 , pp. 105-119
    • Wilson, C.B.1    Makar, K.W.2    Shnyreva, M.3    Fitzpatrick, D.R.4
  • 33
    • 33646196946 scopus 로고    scopus 로고
    • Regulation of Th2 differentiation and Il4 locus accessibility
    • Ansel KM, Djuretic I, Tanasa B, Rao A (2006) Regulation of Th2 differentiation and Il4 locus accessibility. Annu Rev Immunol 24: 607-656.
    • (2006) Annu Rev Immunol , vol.24 , pp. 607-656
    • Ansel, K.M.1    Djuretic, I.2    Tanasa, B.3    Rao, A.4
  • 34
    • 23944472219 scopus 로고    scopus 로고
    • Loss of adenomatous polyposis coli gene function disrupts thymic development
    • Gounari F, Chang R, Cowan J, Guo Z, Dose M, et al. (2005) Loss of adenomatous polyposis coli gene function disrupts thymic development. Nat Immunol 6: 800-809.
    • (2005) Nat Immunol , vol.6 , pp. 800-809
    • Gounari, F.1    Chang, R.2    Cowan, J.3    Guo, Z.4    Dose, M.5
  • 35
    • 30444451906 scopus 로고    scopus 로고
    • Critical function for SIP, a ubiquitin E3 ligase component of the beta-catenin degradation pathway, for thymocyte development and G1 checkpoint
    • Fukushima T, Zapata JM, Singha NC, Thomas M, Kress CL, et al. (2006) Critical function for SIP, a ubiquitin E3 ligase component of the beta-catenin degradation pathway, for thymocyte development and G1 checkpoint. Immunity 24: 29-39.
    • (2006) Immunity , vol.24 , pp. 29-39
    • Fukushima, T.1    Zapata, J.M.2    Singha, N.C.3    Thomas, M.4    Kress, C.L.5
  • 36
    • 0037502235 scopus 로고    scopus 로고
    • Bcl11b is required for differentiation and survival of alphabeta T lymphocytes
    • Wakabayashi Y, Watanabe H, Inoue J, Takeda N, Sakata J, et al. (2003) Bcl11b is required for differentiation and survival of alphabeta T lymphocytes. Nat Immunol 4: 533-539.
    • (2003) Nat Immunol , vol.4 , pp. 533-539
    • Wakabayashi, Y.1    Watanabe, H.2    Inoue, J.3    Takeda, N.4    Sakata, J.5
  • 37
    • 3543011330 scopus 로고    scopus 로고
    • The T-cell receptor beta variable gene promoter is required for efficient V beta rearrangement but not allelic exclusion
    • Ryu CJ, Haines BB, Lee HR, Kang YH, Draganov DD, et al. (2004) The T-cell receptor beta variable gene promoter is required for efficient V beta rearrangement but not allelic exclusion. Mol Cell Biol 24: 7015-7023.
    • (2004) Mol Cell Biol , vol.24 , pp. 7015-7023
    • Ryu, C.J.1    Haines, B.B.2    Lee, H.R.3    Kang, Y.H.4    Draganov, D.D.5
  • 39
    • 34247590210 scopus 로고    scopus 로고
    • 14-3-3 proteins bind both filamin and alphaLbeta2 integrin in activated T cells
    • Nurmi SM, Gahmberg CG, Fagerholm SC (2006) 14-3-3 proteins bind both filamin and alphaLbeta2 integrin in activated T cells. Ann N Y Acad Sci 1090: 318-325.
    • (2006) Ann N Y Acad Sci , vol.1090 , pp. 318-325
    • Nurmi, S.M.1    Gahmberg, C.G.2    Fagerholm, S.C.3
  • 40
    • 0032524621 scopus 로고    scopus 로고
    • Characterization of human hect domain family members and their interaction with UbcH5 and UbcH7
    • Schwarz SE, Rosa JL, Scheffner M (1998) Characterization of human hect domain family members and their interaction with UbcH5 and UbcH7. J Biol Chem 273: 12148-12154.
    • (1998) J Biol Chem , vol.273 , pp. 12148-12154
    • Schwarz, S.E.1    Rosa, J.L.2    Scheffner, M.3
  • 41
    • 0028876893 scopus 로고
    • Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor
    • Lee JW, Choi HS, Gyuris J, Brent R, Moore DD (1995) Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor. Mol Endocrinol 9: 243-254.
    • (1995) Mol Endocrinol , vol.9 , pp. 243-254
    • Lee, J.W.1    Choi, H.S.2    Gyuris, J.3    Brent, R.4    Moore, D.D.5
  • 42
    • 0034266806 scopus 로고    scopus 로고
    • RING finger proteins: Mediators of ubiquitin ligase activity
    • Joazeiro CA, Weissman AM (2000) RING finger proteins: mediators of ubiquitin ligase activity. Cell 102: 549-552.
    • (2000) Cell , vol.102 , pp. 549-552
    • Joazeiro, C.A.1    Weissman, A.M.2
  • 43
    • 34748851341 scopus 로고    scopus 로고
    • Cell and molecular biology of Notch
    • Fiuza UM, Arias AM (2007) Cell and molecular biology of Notch. J Endocrinol 194: 459-474.
    • (2007) J Endocrinol , vol.194 , pp. 459-474
    • Fiuza, U.M.1    Arias, A.M.2
  • 44
    • 34249293370 scopus 로고    scopus 로고
    • The E3 ubiquitin ligase Itch in T cell activation, differentiation, and tolerance
    • Liu YC (2007) The E3 ubiquitin ligase Itch in T cell activation, differentiation, and tolerance. Semin Immunol 19: 197-205.
    • (2007) Semin Immunol , vol.19 , pp. 197-205
    • Liu, Y.C.1
  • 45
    • 33845361228 scopus 로고    scopus 로고
    • Itch genetically interacts with Notch1 in a mouse autoimmune disease model
    • Matesic LE, Haines DC, Copeland NG, Jenkins NA (2006) Itch genetically interacts with Notch1 in a mouse autoimmune disease model. Hum Mol Genet 15: 3485-3497.
    • (2006) Hum Mol Genet , vol.15 , pp. 3485-3497
    • Matesic, L.E.1    Haines, D.C.2    Copeland, N.G.3    Jenkins, N.A.4
  • 46
    • 43549117297 scopus 로고    scopus 로고
    • Essential role of Notch signaling in effector memory CD8+ T cell-mediated airway hyperresponsiveness and inflammation
    • Okamoto M, Takeda K, Joetham A, Ohnishi H, Matsuda H, et al. (2008) Essential role of Notch signaling in effector memory CD8+ T cell-mediated airway hyperresponsiveness and inflammation. J Exp Med 205: 1087-1097.
    • (2008) J Exp Med , vol.205 , pp. 1087-1097
    • Okamoto, M.1    Takeda, K.2    Joetham, A.3    Ohnishi, H.4    Matsuda, H.5
  • 47
    • 0029023204 scopus 로고
    • Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila Delta
    • Bettenhausen B, Hrabe de Angelis M, Simon D, Guenet JL, Gossler A (1995) Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila Delta. Development 121: 2407-2418.
    • (1995) Development , vol.121 , pp. 2407-2418
    • Bettenhausen, B.1    Hrabe de Angelis, M.2    Simon, D.3    Guenet, J.L.4    Gossler, A.5
  • 48
    • 0038147273 scopus 로고    scopus 로고
    • Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH)
    • Wang J, Hegele RA (2003) Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH). Hum Genet 112: 404-408.
    • (2003) Hum Genet , vol.112 , pp. 404-408
    • Wang, J.1    Hegele, R.A.2
  • 49
    • 2942756170 scopus 로고    scopus 로고
    • Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration
    • Wang J, Huff AM, Spence JD, Hegele RA (2004) Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration. Clin Genet 65: 483-486.
    • (2004) Clin Genet , vol.65 , pp. 483-486
    • Wang, J.1    Huff, A.M.2    Spence, J.D.3    Hegele, R.A.4
  • 50
    • 13844281063 scopus 로고    scopus 로고
    • Molecular effects of homocysteine on cbEGF domain structure: Insights into the pathogenesis of homocystinuria
    • Hutchinson S, Aplin RT, Webb H, Kettle S, Timmermans J, et al. (2005) Molecular effects of homocysteine on cbEGF domain structure: insights into the pathogenesis of homocystinuria. J Mol Biol 346: 833-844.
    • (2005) J Mol Biol , vol.346 , pp. 833-844
    • Hutchinson, S.1    Aplin, R.T.2    Webb, H.3    Kettle, S.4    Timmermans, J.5
  • 53
    • 0030221366 scopus 로고    scopus 로고
    • Human isopentenyl diphosphate: Dimethylallyl diphosphate isomerase: overproduction, purification, and characterization
    • Hahn FM, Xuan JW, Chambers AF, Poulter CD (1996) Human isopentenyl diphosphate: dimethylallyl diphosphate isomerase: overproduction, purification, and characterization. Arch Biochem Biophys 332: 30-34.
    • (1996) Arch Biochem Biophys , vol.332 , pp. 30-34
    • Hahn, F.M.1    Xuan, J.W.2    Chambers, A.F.3    Poulter, C.D.4
  • 54
    • 0025248446 scopus 로고
    • Isolation and sequence of the human farnesyl pyrophosphate synthetase cDNA. Coordinate regulation of the mRNAs for farnesyl pyrophosphate synthetase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and 3-hydroxy-3-methylglutaryl coenzyme A synthase by phorbol ester
    • Wilkin DJ, Kutsunai SY, Edwards PA (1990) Isolation and sequence of the human farnesyl pyrophosphate synthetase cDNA. Coordinate regulation of the mRNAs for farnesyl pyrophosphate synthetase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and 3-hydroxy-3-methylglutaryl coenzyme A synthase by phorbol ester. J Biol Chem 265: 4607-4614.
    • (1990) J Biol Chem , vol.265 , pp. 4607-4614
    • Wilkin, D.J.1    Kutsunai, S.Y.2    Edwards, P.A.3
  • 55
    • 0035826909 scopus 로고    scopus 로고
    • Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10
    • Kojro E, Gimpl G, Lammich S, Marz W, Fahrenholz F (2001) Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10. Proc Natl Acad Sci U S A 98: 5815-5820.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 5815-5820
    • Kojro, E.1    Gimpl, G.2    Lammich, S.3    Marz, W.4    Fahrenholz, F.5
  • 56
    • 0036796421 scopus 로고    scopus 로고
    • The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts
    • Hartmann D, de Strooper B, Serneels L, Craessaerts K, Herreman A, et al. (2002) The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts. Hum Mol Genet 11: 2615-2624.
    • (2002) Hum Mol Genet , vol.11 , pp. 2615-2624
    • Hartmann, D.1    de Strooper, B.2    Serneels, L.3    Craessaerts, K.4    Herreman, A.5
  • 57
    • 53049089639 scopus 로고    scopus 로고
    • Direct and potent regulation of gamma-secretase by its lipid microenvironment
    • Osenkowski P, Ye W, Wang R, Wolfe MS, Selkoe DJ (2008) Direct and potent regulation of gamma-secretase by its lipid microenvironment. J Biol Chem 283: 22529-22540.
    • (2008) J Biol Chem , vol.283 , pp. 22529-22540
    • Osenkowski, P.1    Ye, W.2    Wang, R.3    Wolfe, M.S.4    Selkoe, D.J.5
  • 58
  • 59
    • 0028017412 scopus 로고
    • Bone loss associated with a high fibre weight reduction diet in postmenopausal women
    • Avenell A, Richmond PR, Lean ME, Reid DM (1994) Bone loss associated with a high fibre weight reduction diet in postmenopausal women. Eur J Clin Nutr 48: 561-566.
    • (1994) Eur J Clin Nutr , vol.48 , pp. 561-566
    • Avenell, A.1    Richmond, P.R.2    Lean, M.E.3    Reid, D.M.4
  • 60
    • 0036029695 scopus 로고    scopus 로고
    • Relationship between body composition and bone mineral content in young and elderly women
    • Bedogni G, Mussi C, Malavolti M, Borghi A, Poli M, et al. (2002) Relationship between body composition and bone mineral content in young and elderly women. Ann Hum Biol 29: 559-565.
    • (2002) Ann Hum Biol , vol.29 , pp. 559-565
    • Bedogni, G.1    Mussi, C.2    Malavolti, M.3    Borghi, A.4    Poli, M.5
  • 61
    • 0031034487 scopus 로고    scopus 로고
    • Fat or lean tissue mass: Which one is the major determinant of bone mineral mass in healthy postmenopausal women?
    • Chen Z, Lohman TG, Stini WA, Ritenbaugh C, Aickin M (1997) Fat or lean tissue mass: which one is the major determinant of bone mineral mass in healthy postmenopausal women? J Bone Miner Res 12: 144-151.
    • (1997) J Bone Miner Res , vol.12 , pp. 144-151
    • Chen, Z.1    Lohman, T.G.2    Stini, W.A.3    Ritenbaugh, C.4    Aickin, M.5
  • 62
    • 0038180840 scopus 로고    scopus 로고
    • Bone mineral density correlates strongly with basal metabolic rate in postmenopausal women
    • Choi JW, Pai SH (2003) Bone mineral density correlates strongly with basal metabolic rate in postmenopausal women. Clin Chim Acta 333: 79-84.
    • (2003) Clin Chim Acta , vol.333 , pp. 79-84
    • Choi, J.W.1    Pai, S.H.2
  • 63
    • 0030881973 scopus 로고    scopus 로고
    • Obesity, and bone strength and "mass": A tutorial based on insights from a new paradigm
    • Frost HM (1997) Obesity, and bone strength and "mass": a tutorial based on insights from a new paradigm. Bone 21: 211-214.
    • (1997) Bone , vol.21 , pp. 211-214
    • Frost, H.M.1
  • 64
    • 0034107179 scopus 로고    scopus 로고
    • Risk factors for longitudinal bone loss in elderly men and women: The Framingham Osteoporosis Study
    • Hannan MT, Felson DT, Dawson-Hughes B, Tucker KL, Cupples LA, et al. (2000) Risk factors for longitudinal bone loss in elderly men and women: the Framingham Osteoporosis Study. J Bone Miner Res 15: 710-720.
    • (2000) J Bone Miner Res , vol.15 , pp. 710-720
    • Hannan, M.T.1    Felson, D.T.2    Dawson-Hughes, B.3    Tucker, K.L.4    Cupples, L.A.5
  • 65
    • 33750453786 scopus 로고    scopus 로고
    • Convergence between bone and energy homeostases: Leptin regulation of bone mass
    • Karsenty G (2006) Convergence between bone and energy homeostases: leptin regulation of bone mass. Cell Metab 4: 341-348.
    • (2006) Cell Metab , vol.4 , pp. 341-348
    • Karsenty, G.1
  • 66
    • 34547690686 scopus 로고    scopus 로고
    • Endocrine regulation of energy metabolism by the skeleton
    • Lee NK, Sowa H, Hinoi E, Ferron M, Ahn JD, et al. (2007) Endocrine regulation of energy metabolism by the skeleton. Cell 130: 456-469.
    • (2007) Cell , vol.130 , pp. 456-469
    • Lee, N.K.1    Sowa, H.2    Hinoi, E.3    Ferron, M.4    Ahn, J.D.5
  • 67
    • 1842454974 scopus 로고    scopus 로고
    • Specification of vertebral identity is coupled to Notch signalling and the segmentation clock
    • Cordes R, Schuster-Gossler K, Serth K, Gossler A (2004) Specification of vertebral identity is coupled to Notch signalling and the segmentation clock. Development 131: 1221-1233.
    • (2004) Development , vol.131 , pp. 1221-1233
    • Cordes, R.1    Schuster-Gossler, K.2    Serth, K.3    Gossler, A.4
  • 68
    • 0032933351 scopus 로고    scopus 로고
    • Siah-1 N-terminal RING domain is required for proteolysis function, and C-terminal sequences regulate oligomerization and binding to target proteins
    • Hu G, Fearon ER (1999) Siah-1 N-terminal RING domain is required for proteolysis function, and C-terminal sequences regulate oligomerization and binding to target proteins. Mol Cell Biol 19: 724-732.
    • (1999) Mol Cell Biol , vol.19 , pp. 724-732
    • Hu, G.1    Fearon, E.R.2
  • 69
    • 0038070064 scopus 로고    scopus 로고
    • Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1
    • Okabe H, Satoh S, Furukawa Y, Kato T, Hasegawa S, et al. (2003) Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1. Cancer Res 63: 3043-3048.
    • (2003) Cancer Res , vol.63 , pp. 3043-3048
    • Okabe, H.1    Satoh, S.2    Furukawa, Y.3    Kato, T.4    Hasegawa, S.5
  • 70
    • 0032525309 scopus 로고    scopus 로고
    • p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: Suppression by BAG-1
    • Matsuzawa S, Takayama S, Froesch BA, Zapata JM, Reed JC (1998) p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: suppression by BAG-1. Embo J 17: 2736-2747.
    • (1998) Embo J , vol.17 , pp. 2736-2747
    • Matsuzawa, S.1    Takayama, S.2    Froesch, B.A.3    Zapata, J.M.4    Reed, J.C.5
  • 72
    • 11244351579 scopus 로고    scopus 로고
    • Function and regulation of cullin-RING ubiquitin ligases
    • Petroski MD, Deshaies RJ (2005) Function and regulation of cullin-RING ubiquitin ligases. Nat Rev Mol Cell Biol 6: 9-20.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 9-20
    • Petroski, M.D.1    Deshaies, R.J.2
  • 73
    • 27644561755 scopus 로고    scopus 로고
    • Hypoxia requires notch signaling to maintain the undifferentiated cell state
    • Gustafsson MV, Zheng X, Pereira T, Gradin K, Jin S, et al. (2005) Hypoxia requires notch signaling to maintain the undifferentiated cell state. Dev Cell 9: 617-628.
    • (2005) Dev Cell , vol.9 , pp. 617-628
    • Gustafsson, M.V.1    Zheng, X.2    Pereira, T.3    Gradin, K.4    Jin, S.5
  • 74
    • 33646471404 scopus 로고    scopus 로고
    • Hypoxia-regulated differentiation: Let's step it up a Notch
    • Sainson RC, Harris AL (2006) Hypoxia-regulated differentiation: let's step it up a Notch. Trends Mol Med 12: 141-143.
    • (2006) Trends Mol Med , vol.12 , pp. 141-143
    • Sainson, R.C.1    Harris, A.L.2
  • 75
    • 0037343426 scopus 로고    scopus 로고
    • A review and comparison of the murine alpha1-antitrypsin and alpha1-antichymotrypsin multigene clusters with the human clade A serpins
    • Forsyth S, Horvath A, Coughlin P (2003) A review and comparison of the murine alpha1-antitrypsin and alpha1-antichymotrypsin multigene clusters with the human clade A serpins. Genomics 81: 336-345.
    • (2003) Genomics , vol.81 , pp. 336-345
    • Forsyth, S.1    Horvath, A.2    Coughlin, P.3
  • 76
    • 0035115958 scopus 로고    scopus 로고
    • Novel roles of kallistatin, a specific tissue kallikrein inhibitor, in vascular remodeling
    • Chao J, Miao RQ, Chen V, Chen LM, Chao L (2001) Novel roles of kallistatin, a specific tissue kallikrein inhibitor, in vascular remodeling. Biol Chem 382: 15-21.
    • (2001) Biol Chem , vol.382 , pp. 15-21
    • Chao, J.1    Miao, R.Q.2    Chen, V.3    Chen, L.M.4    Chao, L.5
  • 77
    • 42349108155 scopus 로고    scopus 로고
    • Salutary effect of kallistatin in salt-induced renal injury, inflammation, and fibrosis via antioxidative stress
    • Shen B, Hagiwara M, Yao YY, Chao L, Chao J (2008) Salutary effect of kallistatin in salt-induced renal injury, inflammation, and fibrosis via antioxidative stress. Hypertension 51: 1358-1365.
    • (2008) Hypertension , vol.51 , pp. 1358-1365
    • Shen, B.1    Hagiwara, M.2    Yao, Y.Y.3    Chao, L.4    Chao, J.5
  • 78
    • 41649105534 scopus 로고    scopus 로고
    • Wnt/Notch signalling and information processing during development
    • Hayward P, Kalmar T, Arias AM (2008) Wnt/Notch signalling and information processing during development. Development 135: 411-424.
    • (2008) Development , vol.135 , pp. 411-424
    • Hayward, P.1    Kalmar, T.2    Arias, A.M.3
  • 81
    • 33846574695 scopus 로고    scopus 로고
    • Expanding the body mass range: Associations between BMR and tissue morphology in wild type and mutant dwarf mice (David mice)
    • Meyer CW, Neubronner J, Rozman J, Stumm G, Osanger A, et al. (2007) Expanding the body mass range: associations between BMR and tissue morphology in wild type and mutant dwarf mice (David mice). J Comp Physiol [B] 177: 183-192.
    • (2007) J Comp Physiol , vol.177 , Issue.B , pp. 183-192
    • Meyer, C.W.1    Neubronner, J.2    Rozman, J.3    Stumm, G.4    Osanger, A.5
  • 82
    • 0000076488 scopus 로고
    • The effect of apparatus, extraction time, and solvent type on lipid extractions of snow geese
    • Dobush GR, Ankney CD, Krementz DG (1985) The effect of apparatus, extraction time, and solvent type on lipid extractions of snow geese. Canadian Journal of Zoology 63: 1917-1920.
    • (1985) Canadian Journal of Zoology , vol.63 , pp. 1917-1920
    • Dobush, G.R.1    Ankney, C.D.2    Krementz, D.G.3
  • 83
    • 52049125697 scopus 로고    scopus 로고
    • Sighted C3H mice - a tool for analysing the influence of vision on mouse behaviour?
    • Hoelter SM, Dalke C, Kallnik M, Becker L, Horsch M, et al. (2008) "Sighted C3H" mice - a tool for analysing the influence of vision on mouse behaviour? Front Biosci 13: 5810-5823.
    • (2008) Front Biosci , vol.13 , pp. 5810-5823
    • Hoelter, S.M.1    Dalke, C.2    Kallnik, M.3    Becker, L.4    Horsch, M.5
  • 85
    • 32144464546 scopus 로고    scopus 로고
    • Genotype-specific environmental impact on the variance of blood values in inbred and F1 hybrid mice
    • Klempt M, Rathkolb B, Fuchs E, Hrabé de Angelis M, Wolf E, et al. (2006) Genotype-specific environmental impact on the variance of blood values in inbred and F1 hybrid mice. Mamm Genome 17: 93-102.
    • (2006) Mamm Genome , vol.17 , pp. 93-102
    • Klempt, M.1    Rathkolb, B.2    Fuchs, E.3    Hrabé de Angelis, M.4    Wolf, E.5
  • 86
    • 34249024263 scopus 로고    scopus 로고
    • Mouse phenotyping: Immunology
    • Hrabe de Angelis M, Chambon P, Brown SD, eds, Weinheim: Whiley-VCH Verlag. pp
    • Kalaydjiev S, Franz T, Busch DH (2006) Mouse phenotyping: immunology. In: Hrabe de Angelis M, Chambon P, Brown SD, eds. Standards of Mouse Models Phenotyping. Weinheim: Whiley-VCH Verlag. pp 237-252.
    • (2006) Standards of Mouse Models Phenotyping , pp. 237-252
    • Kalaydjiev, S.1    Franz, T.2    Busch, D.H.3
  • 87
    • 0033860044 scopus 로고    scopus 로고
    • Screening for dysmorphological abnormalities - a powerful tool to isolate new mouse mutants
    • Fuchs H, Schughart K, Wolf E, Balling R, Hrabe de Angelis M (2000) Screening for dysmorphological abnormalities - a powerful tool to isolate new mouse mutants. Mamm Genome 11: 528-530.
    • (2000) Mamm Genome , vol.11 , pp. 528-530
    • Fuchs, H.1    Schughart, K.2    Wolf, E.3    Balling, R.4    Hrabe de Angelis, M.5
  • 88
    • 0033818954 scopus 로고    scopus 로고
    • A concise guide to cDNA microarray analysis
    • passim
    • Hegde P, Qi R, Abernathy K, Gay C, Dharap S, et al. (2000) A concise guide to cDNA microarray analysis. Biotechniques 29: 548-550, 552-544, 556 passim.
    • (2000) Biotechniques , vol.29
    • Hegde, P.1    Qi, R.2    Abernathy, K.3    Gay, C.4    Dharap, S.5
  • 89
    • 0037311919 scopus 로고    scopus 로고
    • TM4: A free, open-source system for microarray data management and analysis
    • Saeed AI, Sharov V, White J, Li J, Liang W, et al. (2003) TM4: a free, open-source system for microarray data management and analysis. Biotechniques 34: 374-378.
    • (2003) Biotechniques , vol.34 , pp. 374-378
    • Saeed, A.I.1    Sharov, V.2    White, J.3    Li, J.4    Liang, W.5
  • 90
    • 36448991500 scopus 로고    scopus 로고
    • Larkin MA, Blackshields G, Brown NP, Chenna R, McGettigan PA, et al, 2007 Clustal W and Clustal X version 2.0. Bioinformatics 23: 2947-2948
    • Larkin MA, Blackshields G, Brown NP, Chenna R, McGettigan PA, et al. (2007) Clustal W and Clustal X version 2.0. Bioinformatics 23: 2947-2948.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.