-
1
-
-
5444247778
-
Notch signaling: The demise of elegant simplicity
-
Kadesch T (2004) Notch signaling: the demise of elegant simplicity. Curr Opin Genet Dev 14: 506-512.
-
(2004)
Curr Opin Genet Dev
, vol.14
, pp. 506-512
-
-
Kadesch, T.1
-
2
-
-
33947241465
-
SnapShot: Notch signaling pathway
-
Ilagan MX, Kopan R (2007) SnapShot: notch signaling pathway. Cell 128: 1246.
-
(2007)
Cell
, vol.128
, pp. 1246
-
-
Ilagan, M.X.1
Kopan, R.2
-
4
-
-
0344308346
-
Notch signaling in development and disease
-
Harper JA, Yuan JS, Tan JB, Visan I, Guidos CJ (2003) Notch signaling in development and disease. Clin Genet 64: 461-472.
-
(2003)
Clin Genet
, vol.64
, pp. 461-472
-
-
Harper, J.A.1
Yuan, J.S.2
Tan, J.B.3
Visan, I.4
Guidos, C.J.5
-
5
-
-
37449010541
-
The multifaceted role of Notch in cardiac development and disease
-
High FA, Epstein JA (2008) The multifaceted role of Notch in cardiac development and disease. Nat Rev Genet 9: 49-61.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 49-61
-
-
High, F.A.1
Epstein, J.A.2
-
6
-
-
34548164780
-
Notch signaling in vascular development and physiology
-
Gridley T (2007) Notch signaling in vascular development and physiology. Development 134: 2709-2718.
-
(2007)
Development
, vol.134
, pp. 2709-2718
-
-
Gridley, T.1
-
7
-
-
34250209506
-
Notch signaling in blood vessels: Who is talking to whom about what?
-
Hofmann JJ, Iruela-Arispe ML (2007) Notch signaling in blood vessels: who is talking to whom about what? Circ Res 100: 1556-1568.
-
(2007)
Circ Res
, vol.100
, pp. 1556-1568
-
-
Hofmann, J.J.1
Iruela-Arispe, M.L.2
-
8
-
-
1842480002
-
Expression of Notch-1 and its ligand Jagged-1 in rat liver during liver regeneration
-
Kohler C, Bell AW, Bowen WC, Monga SP, Fleig W, et al. (2004) Expression of Notch-1 and its ligand Jagged-1 in rat liver during liver regeneration. Hepatology 39: 1056-1065.
-
(2004)
Hepatology
, vol.39
, pp. 1056-1065
-
-
Kohler, C.1
Bell, A.W.2
Bowen, W.C.3
Monga, S.P.4
Fleig, W.5
-
9
-
-
33748448512
-
Manipulation of endogenous neural stem cells following ischemic brain injury
-
Leker RR (2006) Manipulation of endogenous neural stem cells following ischemic brain injury. Pathophysiol Haemost Thromb 35: 58-62.
-
(2006)
Pathophysiol Haemost Thromb
, vol.35
, pp. 58-62
-
-
Leker, R.R.1
-
10
-
-
0036014932
-
Transforming growth factor-beta induces renal epithelial jagged-1 expression in fibrotic disease
-
Morrissey J, Guo G, Moridaira K, Fitzgerald M, McCracken R, et al. (2002) Transforming growth factor-beta induces renal epithelial jagged-1 expression in fibrotic disease. J Am Soc Nephrol 13: 1499-1508.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 1499-1508
-
-
Morrissey, J.1
Guo, G.2
Moridaira, K.3
Fitzgerald, M.4
McCracken, R.5
-
11
-
-
43749117539
-
Expression and function of the Delta-1/Notch-2/Hes-1 pathway during experimental acute kidney injury
-
Kobayashi T, Terada Y, Kuwana H, Tanaka H, Okado T, et al. (2008) Expression and function of the Delta-1/Notch-2/Hes-1 pathway during experimental acute kidney injury. Kidney Int 73: 1240-1250.
-
(2008)
Kidney Int
, vol.73
, pp. 1240-1250
-
-
Kobayashi, T.1
Terada, Y.2
Kuwana, H.3
Tanaka, H.4
Okado, T.5
-
12
-
-
38649140167
-
Notch signaling is required for exocrine regeneration after acute pancreatitis
-
Siveke JT, Lubeseder-Martellato C, Lee M, Mazur PK, Nakhai H, et al. (2008) Notch signaling is required for exocrine regeneration after acute pancreatitis. Gastroenterology 134: 544-555.
-
(2008)
Gastroenterology
, vol.134
, pp. 544-555
-
-
Siveke, J.T.1
Lubeseder-Martellato, C.2
Lee, M.3
Mazur, P.K.4
Nakhai, H.5
-
13
-
-
2342578680
-
Suppressor screen in Mpl-/- mice: C-Myb mutation causes supraphysiological production of platelets in the absence of thrombopoietin signaling
-
Carpinelli MR, Hilton DJ, Metcalf D, Antonchuk JL, Hyland CD, et al. (2004) Suppressor screen in Mpl-/- mice: c-Myb mutation causes supraphysiological production of platelets in the absence of thrombopoietin signaling. Proc Natl Acad Sci U S A 101: 6553-6558.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 6553-6558
-
-
Carpinelli, M.R.1
Hilton, D.J.2
Metcalf, D.3
Antonchuk, J.L.4
Hyland, C.D.5
-
14
-
-
34249010460
-
A genetic screen for modifiers of the delta1-dependent notch signaling function in the mouse
-
Rubio-Aliaga I, Soewarto D, Wagner S, Klaften M, Fuchs H, et al. (2007) A genetic screen for modifiers of the delta1-dependent notch signaling function in the mouse. Genetics 175: 1451-1463.
-
(2007)
Genetics
, vol.175
, pp. 1451-1463
-
-
Rubio-Aliaga, I.1
Soewarto, D.2
Wagner, S.3
Klaften, M.4
Fuchs, H.5
-
15
-
-
0030976083
-
Maintenance of somite borders in mice requires the Delta homologue DII1
-
Hrabe de Angelis M, McIntyre J 2nd, Gossler A (1997) Maintenance of somite borders in mice requires the Delta homologue DII1. Nature 386: 717-721.
-
(1997)
Nature
, vol.386
, pp. 717-721
-
-
Hrabe de Angelis, M.1
McIntyre 2nd, J.2
Gossler, A.3
-
16
-
-
0032897080
-
Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1
-
Xue Y, Gao X, Lindsell CE, Norton CR, Chang B, et al. (1999) Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1. Hum Mol Genet 8: 723-730.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 723-730
-
-
Xue, Y.1
Gao, X.2
Lindsell, C.E.3
Norton, C.R.4
Chang, B.5
-
17
-
-
0028216808
-
Notch1 is essential for postimplantation development in mice
-
Swiatek PJ, Lindsell CE, del Amo FF, Weinmaster G, Gridley T (1994) Notch1 is essential for postimplantation development in mice. Genes Dev 8: 707-719.
-
(1994)
Genes Dev
, vol.8
, pp. 707-719
-
-
Swiatek, P.J.1
Lindsell, C.E.2
del Amo, F.F.3
Weinmaster, G.4
Gridley, T.5
-
18
-
-
0030273134
-
Expression of the Notch 3 intracellular domain in mouse central nervous system progenitor cells is lethal and leads to disturbed neural tube development
-
Lardelli M, Williams R, Mitsiadis T, Lendahl U (1996) Expression of the Notch 3 intracellular domain in mouse central nervous system progenitor cells is lethal and leads to disturbed neural tube development. Mech Dev 59: 177-190.
-
(1996)
Mech Dev
, vol.59
, pp. 177-190
-
-
Lardelli, M.1
Williams, R.2
Mitsiadis, T.3
Lendahl, U.4
-
19
-
-
0032054238
-
Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice
-
Jiang R, Lan Y, Chapman HD, Shawber C, Norton CR, et al. (1998) Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice. Genes Dev 12: 1046-1057.
-
(1998)
Genes Dev
, vol.12
, pp. 1046-1057
-
-
Jiang, R.1
Lan, Y.2
Chapman, H.D.3
Shawber, C.4
Norton, C.R.5
-
20
-
-
21444455843
-
Introducing the German Mouse Clinic: Open access platform for standardized phenotyping
-
Gailus-Durner V, Fuchs H, Becker L, Bolle I, Brielmeier M, et al. (2005) Introducing the German Mouse Clinic: open access platform for standardized phenotyping. Nat Methods 2: 403-404.
-
(2005)
Nat Methods
, vol.2
, pp. 403-404
-
-
Gailus-Durner, V.1
Fuchs, H.2
Becker, L.3
Bolle, I.4
Brielmeier, M.5
-
21
-
-
27644501458
-
EMPReSS: Standardized phenotype screens for functional annotation of the mouse genome
-
Brown SD, Chambon P, Hrabé de Angelis M (2005) EMPReSS: standardized phenotype screens for functional annotation of the mouse genome. Nat Genet 37: 1155.
-
(2005)
Nat Genet
, vol.37
, pp. 1155
-
-
Brown, S.D.1
Chambon, P.2
Hrabé de Angelis, M.3
-
22
-
-
51749111621
-
Phenotypic characterization of mouse models for bone-related diseases in the German Mouse Clinic
-
Fuchs H, Lisse T, Hans W, Abe K, Thiele F, et al. (2008) Phenotypic characterization of mouse models for bone-related diseases in the German Mouse Clinic. J Musculoskelet Neuronal Interact 8: 13-14.
-
(2008)
J Musculoskelet Neuronal Interact
, vol.8
, pp. 13-14
-
-
Fuchs, H.1
Lisse, T.2
Hans, W.3
Abe, K.4
Thiele, F.5
-
23
-
-
35048883475
-
Genetic background modifies inner ear and eye phenotypes of jag1 heterozygous mice
-
Kiernan AE, Li R, Hawes NL, Churchill GA, Gridley T (2007) Genetic background modifies inner ear and eye phenotypes of jag1 heterozygous mice. Genetics 177: 307-311.
-
(2007)
Genetics
, vol.177
, pp. 307-311
-
-
Kiernan, A.E.1
Li, R.2
Hawes, N.L.3
Churchill, G.A.4
Gridley, T.5
-
24
-
-
41549157255
-
Systematic gene expression profiling of mouse model series reveals coexpressed genes
-
Horsch M, Schadler S, Gailus-Durner V, Fuchs H, Meyer H, et al. (2008) Systematic gene expression profiling of mouse model series reveals coexpressed genes. Proteomics 8: 1248-1256.
-
(2008)
Proteomics
, vol.8
, pp. 1248-1256
-
-
Horsch, M.1
Schadler, S.2
Gailus-Durner, V.3
Fuchs, H.4
Meyer, H.5
-
25
-
-
0037386594
-
Delta-Notch signaling controls the generation of neurons/glia from neural stem cells in a stepwise process
-
Grandbarbe L, Bouissac J, Rand M, Hrabe de Angelis M, Artavanis-Tsakonas S, et al. (2003) Delta-Notch signaling controls the generation of neurons/glia from neural stem cells in a stepwise process. Development 130: 1391-1402.
-
(2003)
Development
, vol.130
, pp. 1391-1402
-
-
Grandbarbe, L.1
Bouissac, J.2
Rand, M.3
Hrabe de Angelis, M.4
Artavanis-Tsakonas, S.5
-
27
-
-
34247224342
-
Regulation of lymphocyte development by Notch signaling
-
Tanigaki K, Honjo T (2007) Regulation of lymphocyte development by Notch signaling. Nat Immunol 8: 451-456.
-
(2007)
Nat Immunol
, vol.8
, pp. 451-456
-
-
Tanigaki, K.1
Honjo, T.2
-
28
-
-
29244451407
-
Identification of Dll1 (Delta1) target genes during mouse embryogenesis using differential expression profiling
-
Machka C, Kersten M, Zobawa M, Harder A, Horsch M, et al. (2005) Identification of Dll1 (Delta1) target genes during mouse embryogenesis using differential expression profiling. Gene Expr Patterns 6: 94-101.
-
(2005)
Gene Expr Patterns
, vol.6
, pp. 94-101
-
-
Machka, C.1
Kersten, M.2
Zobawa, M.3
Harder, A.4
Horsch, M.5
-
29
-
-
27644512860
-
Efficient and fast targeted production of murine models based on ENU mutagenesis
-
Augustin M, Sedlmeier R, Peters T, Huffstadt U, Kochmann E, et al. (2005) Efficient and fast targeted production of murine models based on ENU mutagenesis. Mamm Genome 16: 405-413.
-
(2005)
Mamm Genome
, vol.16
, pp. 405-413
-
-
Augustin, M.1
Sedlmeier, R.2
Peters, T.3
Huffstadt, U.4
Kochmann, E.5
-
30
-
-
50549096379
-
Genetic influence on immune phenotype revealed strain-specific variations in peripheral blood lineages
-
Petkova SB, Yuan R, Tsaih SW, Schott W, Roopenian DC, et al. (2008) Genetic influence on immune phenotype revealed strain-specific variations in peripheral blood lineages. Physiol Genomics 34: 304-314.
-
(2008)
Physiol Genomics
, vol.34
, pp. 304-314
-
-
Petkova, S.B.1
Yuan, R.2
Tsaih, S.W.3
Schott, W.4
Roopenian, D.C.5
-
31
-
-
2942659675
-
Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo
-
Hozumi K, Negishi N, Suzuki D, Abe N, Sotomaru Y, et al. (2004) Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo. Nat Immunol 5: 638-644.
-
(2004)
Nat Immunol
, vol.5
, pp. 638-644
-
-
Hozumi, K.1
Negishi, N.2
Suzuki, D.3
Abe, N.4
Sotomaru, Y.5
-
32
-
-
14244260068
-
DNA methylation and the expanding epigenetics of T cell lineage commitment
-
Wilson CB, Makar KW, Shnyreva M, Fitzpatrick DR (2005) DNA methylation and the expanding epigenetics of T cell lineage commitment. Semin Immunol 17: 105-119.
-
(2005)
Semin Immunol
, vol.17
, pp. 105-119
-
-
Wilson, C.B.1
Makar, K.W.2
Shnyreva, M.3
Fitzpatrick, D.R.4
-
33
-
-
33646196946
-
Regulation of Th2 differentiation and Il4 locus accessibility
-
Ansel KM, Djuretic I, Tanasa B, Rao A (2006) Regulation of Th2 differentiation and Il4 locus accessibility. Annu Rev Immunol 24: 607-656.
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 607-656
-
-
Ansel, K.M.1
Djuretic, I.2
Tanasa, B.3
Rao, A.4
-
34
-
-
23944472219
-
Loss of adenomatous polyposis coli gene function disrupts thymic development
-
Gounari F, Chang R, Cowan J, Guo Z, Dose M, et al. (2005) Loss of adenomatous polyposis coli gene function disrupts thymic development. Nat Immunol 6: 800-809.
-
(2005)
Nat Immunol
, vol.6
, pp. 800-809
-
-
Gounari, F.1
Chang, R.2
Cowan, J.3
Guo, Z.4
Dose, M.5
-
35
-
-
30444451906
-
Critical function for SIP, a ubiquitin E3 ligase component of the beta-catenin degradation pathway, for thymocyte development and G1 checkpoint
-
Fukushima T, Zapata JM, Singha NC, Thomas M, Kress CL, et al. (2006) Critical function for SIP, a ubiquitin E3 ligase component of the beta-catenin degradation pathway, for thymocyte development and G1 checkpoint. Immunity 24: 29-39.
-
(2006)
Immunity
, vol.24
, pp. 29-39
-
-
Fukushima, T.1
Zapata, J.M.2
Singha, N.C.3
Thomas, M.4
Kress, C.L.5
-
36
-
-
0037502235
-
Bcl11b is required for differentiation and survival of alphabeta T lymphocytes
-
Wakabayashi Y, Watanabe H, Inoue J, Takeda N, Sakata J, et al. (2003) Bcl11b is required for differentiation and survival of alphabeta T lymphocytes. Nat Immunol 4: 533-539.
-
(2003)
Nat Immunol
, vol.4
, pp. 533-539
-
-
Wakabayashi, Y.1
Watanabe, H.2
Inoue, J.3
Takeda, N.4
Sakata, J.5
-
37
-
-
3543011330
-
The T-cell receptor beta variable gene promoter is required for efficient V beta rearrangement but not allelic exclusion
-
Ryu CJ, Haines BB, Lee HR, Kang YH, Draganov DD, et al. (2004) The T-cell receptor beta variable gene promoter is required for efficient V beta rearrangement but not allelic exclusion. Mol Cell Biol 24: 7015-7023.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 7015-7023
-
-
Ryu, C.J.1
Haines, B.B.2
Lee, H.R.3
Kang, Y.H.4
Draganov, D.D.5
-
38
-
-
0025906133
-
CD8 is needed for development of cytotoxic T cells but not helper T cells
-
Fung-Leung WP, Schilham MW, Rahemtulla A, Kundig TM, Vollenweider M, et al. (1991) CD8 is needed for development of cytotoxic T cells but not helper T cells. Cell 65: 443-449.
-
(1991)
Cell
, vol.65
, pp. 443-449
-
-
Fung-Leung, W.P.1
Schilham, M.W.2
Rahemtulla, A.3
Kundig, T.M.4
Vollenweider, M.5
-
39
-
-
34247590210
-
14-3-3 proteins bind both filamin and alphaLbeta2 integrin in activated T cells
-
Nurmi SM, Gahmberg CG, Fagerholm SC (2006) 14-3-3 proteins bind both filamin and alphaLbeta2 integrin in activated T cells. Ann N Y Acad Sci 1090: 318-325.
-
(2006)
Ann N Y Acad Sci
, vol.1090
, pp. 318-325
-
-
Nurmi, S.M.1
Gahmberg, C.G.2
Fagerholm, S.C.3
-
40
-
-
0032524621
-
Characterization of human hect domain family members and their interaction with UbcH5 and UbcH7
-
Schwarz SE, Rosa JL, Scheffner M (1998) Characterization of human hect domain family members and their interaction with UbcH5 and UbcH7. J Biol Chem 273: 12148-12154.
-
(1998)
J Biol Chem
, vol.273
, pp. 12148-12154
-
-
Schwarz, S.E.1
Rosa, J.L.2
Scheffner, M.3
-
41
-
-
0028876893
-
Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor
-
Lee JW, Choi HS, Gyuris J, Brent R, Moore DD (1995) Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor. Mol Endocrinol 9: 243-254.
-
(1995)
Mol Endocrinol
, vol.9
, pp. 243-254
-
-
Lee, J.W.1
Choi, H.S.2
Gyuris, J.3
Brent, R.4
Moore, D.D.5
-
42
-
-
0034266806
-
RING finger proteins: Mediators of ubiquitin ligase activity
-
Joazeiro CA, Weissman AM (2000) RING finger proteins: mediators of ubiquitin ligase activity. Cell 102: 549-552.
-
(2000)
Cell
, vol.102
, pp. 549-552
-
-
Joazeiro, C.A.1
Weissman, A.M.2
-
43
-
-
34748851341
-
Cell and molecular biology of Notch
-
Fiuza UM, Arias AM (2007) Cell and molecular biology of Notch. J Endocrinol 194: 459-474.
-
(2007)
J Endocrinol
, vol.194
, pp. 459-474
-
-
Fiuza, U.M.1
Arias, A.M.2
-
44
-
-
34249293370
-
The E3 ubiquitin ligase Itch in T cell activation, differentiation, and tolerance
-
Liu YC (2007) The E3 ubiquitin ligase Itch in T cell activation, differentiation, and tolerance. Semin Immunol 19: 197-205.
-
(2007)
Semin Immunol
, vol.19
, pp. 197-205
-
-
Liu, Y.C.1
-
45
-
-
33845361228
-
Itch genetically interacts with Notch1 in a mouse autoimmune disease model
-
Matesic LE, Haines DC, Copeland NG, Jenkins NA (2006) Itch genetically interacts with Notch1 in a mouse autoimmune disease model. Hum Mol Genet 15: 3485-3497.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 3485-3497
-
-
Matesic, L.E.1
Haines, D.C.2
Copeland, N.G.3
Jenkins, N.A.4
-
46
-
-
43549117297
-
Essential role of Notch signaling in effector memory CD8+ T cell-mediated airway hyperresponsiveness and inflammation
-
Okamoto M, Takeda K, Joetham A, Ohnishi H, Matsuda H, et al. (2008) Essential role of Notch signaling in effector memory CD8+ T cell-mediated airway hyperresponsiveness and inflammation. J Exp Med 205: 1087-1097.
-
(2008)
J Exp Med
, vol.205
, pp. 1087-1097
-
-
Okamoto, M.1
Takeda, K.2
Joetham, A.3
Ohnishi, H.4
Matsuda, H.5
-
47
-
-
0029023204
-
Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila Delta
-
Bettenhausen B, Hrabe de Angelis M, Simon D, Guenet JL, Gossler A (1995) Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila Delta. Development 121: 2407-2418.
-
(1995)
Development
, vol.121
, pp. 2407-2418
-
-
Bettenhausen, B.1
Hrabe de Angelis, M.2
Simon, D.3
Guenet, J.L.4
Gossler, A.5
-
48
-
-
0038147273
-
Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH)
-
Wang J, Hegele RA (2003) Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH). Hum Genet 112: 404-408.
-
(2003)
Hum Genet
, vol.112
, pp. 404-408
-
-
Wang, J.1
Hegele, R.A.2
-
49
-
-
2942756170
-
Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration
-
Wang J, Huff AM, Spence JD, Hegele RA (2004) Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration. Clin Genet 65: 483-486.
-
(2004)
Clin Genet
, vol.65
, pp. 483-486
-
-
Wang, J.1
Huff, A.M.2
Spence, J.D.3
Hegele, R.A.4
-
50
-
-
13844281063
-
Molecular effects of homocysteine on cbEGF domain structure: Insights into the pathogenesis of homocystinuria
-
Hutchinson S, Aplin RT, Webb H, Kettle S, Timmermans J, et al. (2005) Molecular effects of homocysteine on cbEGF domain structure: insights into the pathogenesis of homocystinuria. J Mol Biol 346: 833-844.
-
(2005)
J Mol Biol
, vol.346
, pp. 833-844
-
-
Hutchinson, S.1
Aplin, R.T.2
Webb, H.3
Kettle, S.4
Timmermans, J.5
-
51
-
-
2342464257
-
Homocysteine as a predictive factor for hip fracture in older persons
-
McLean RR, Jacques PF, Selhub J, Tucker KL, Samelson EJ, et al. (2004) Homocysteine as a predictive factor for hip fracture in older persons. N Engl J Med 350: 2042-2049.
-
(2004)
N Engl J Med
, vol.350
, pp. 2042-2049
-
-
McLean, R.R.1
Jacques, P.F.2
Selhub, J.3
Tucker, K.L.4
Samelson, E.J.5
-
52
-
-
2342614847
-
Homocysteine levels and the risk of osteoporotic fracture
-
van Meurs JB, Dhonukshe-Rutten RA, Pluijm SM, van der Klift M, de Jonge R, et al. (2004) Homocysteine levels and the risk of osteoporotic fracture. N Engl J Med 350: 2033-2041.
-
(2004)
N Engl J Med
, vol.350
, pp. 2033-2041
-
-
van Meurs, J.B.1
Dhonukshe-Rutten, R.A.2
Pluijm, S.M.3
van der Klift, M.4
de Jonge, R.5
-
53
-
-
0030221366
-
Human isopentenyl diphosphate: Dimethylallyl diphosphate isomerase: overproduction, purification, and characterization
-
Hahn FM, Xuan JW, Chambers AF, Poulter CD (1996) Human isopentenyl diphosphate: dimethylallyl diphosphate isomerase: overproduction, purification, and characterization. Arch Biochem Biophys 332: 30-34.
-
(1996)
Arch Biochem Biophys
, vol.332
, pp. 30-34
-
-
Hahn, F.M.1
Xuan, J.W.2
Chambers, A.F.3
Poulter, C.D.4
-
54
-
-
0025248446
-
Isolation and sequence of the human farnesyl pyrophosphate synthetase cDNA. Coordinate regulation of the mRNAs for farnesyl pyrophosphate synthetase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and 3-hydroxy-3-methylglutaryl coenzyme A synthase by phorbol ester
-
Wilkin DJ, Kutsunai SY, Edwards PA (1990) Isolation and sequence of the human farnesyl pyrophosphate synthetase cDNA. Coordinate regulation of the mRNAs for farnesyl pyrophosphate synthetase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and 3-hydroxy-3-methylglutaryl coenzyme A synthase by phorbol ester. J Biol Chem 265: 4607-4614.
-
(1990)
J Biol Chem
, vol.265
, pp. 4607-4614
-
-
Wilkin, D.J.1
Kutsunai, S.Y.2
Edwards, P.A.3
-
55
-
-
0035826909
-
Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10
-
Kojro E, Gimpl G, Lammich S, Marz W, Fahrenholz F (2001) Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10. Proc Natl Acad Sci U S A 98: 5815-5820.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 5815-5820
-
-
Kojro, E.1
Gimpl, G.2
Lammich, S.3
Marz, W.4
Fahrenholz, F.5
-
56
-
-
0036796421
-
The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts
-
Hartmann D, de Strooper B, Serneels L, Craessaerts K, Herreman A, et al. (2002) The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts. Hum Mol Genet 11: 2615-2624.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 2615-2624
-
-
Hartmann, D.1
de Strooper, B.2
Serneels, L.3
Craessaerts, K.4
Herreman, A.5
-
57
-
-
53049089639
-
Direct and potent regulation of gamma-secretase by its lipid microenvironment
-
Osenkowski P, Ye W, Wang R, Wolfe MS, Selkoe DJ (2008) Direct and potent regulation of gamma-secretase by its lipid microenvironment. J Biol Chem 283: 22529-22540.
-
(2008)
J Biol Chem
, vol.283
, pp. 22529-22540
-
-
Osenkowski, P.1
Ye, W.2
Wang, R.3
Wolfe, M.S.4
Selkoe, D.J.5
-
58
-
-
48149109123
-
Notch signaling in osteoblasts
-
Canalis E (2008) Notch signaling in osteoblasts. Sci Signal 1: pe17.
-
(2008)
Sci Signal 1: Pe17
-
-
Canalis, E.1
-
59
-
-
0028017412
-
Bone loss associated with a high fibre weight reduction diet in postmenopausal women
-
Avenell A, Richmond PR, Lean ME, Reid DM (1994) Bone loss associated with a high fibre weight reduction diet in postmenopausal women. Eur J Clin Nutr 48: 561-566.
-
(1994)
Eur J Clin Nutr
, vol.48
, pp. 561-566
-
-
Avenell, A.1
Richmond, P.R.2
Lean, M.E.3
Reid, D.M.4
-
60
-
-
0036029695
-
Relationship between body composition and bone mineral content in young and elderly women
-
Bedogni G, Mussi C, Malavolti M, Borghi A, Poli M, et al. (2002) Relationship between body composition and bone mineral content in young and elderly women. Ann Hum Biol 29: 559-565.
-
(2002)
Ann Hum Biol
, vol.29
, pp. 559-565
-
-
Bedogni, G.1
Mussi, C.2
Malavolti, M.3
Borghi, A.4
Poli, M.5
-
61
-
-
0031034487
-
Fat or lean tissue mass: Which one is the major determinant of bone mineral mass in healthy postmenopausal women?
-
Chen Z, Lohman TG, Stini WA, Ritenbaugh C, Aickin M (1997) Fat or lean tissue mass: which one is the major determinant of bone mineral mass in healthy postmenopausal women? J Bone Miner Res 12: 144-151.
-
(1997)
J Bone Miner Res
, vol.12
, pp. 144-151
-
-
Chen, Z.1
Lohman, T.G.2
Stini, W.A.3
Ritenbaugh, C.4
Aickin, M.5
-
62
-
-
0038180840
-
Bone mineral density correlates strongly with basal metabolic rate in postmenopausal women
-
Choi JW, Pai SH (2003) Bone mineral density correlates strongly with basal metabolic rate in postmenopausal women. Clin Chim Acta 333: 79-84.
-
(2003)
Clin Chim Acta
, vol.333
, pp. 79-84
-
-
Choi, J.W.1
Pai, S.H.2
-
63
-
-
0030881973
-
Obesity, and bone strength and "mass": A tutorial based on insights from a new paradigm
-
Frost HM (1997) Obesity, and bone strength and "mass": a tutorial based on insights from a new paradigm. Bone 21: 211-214.
-
(1997)
Bone
, vol.21
, pp. 211-214
-
-
Frost, H.M.1
-
64
-
-
0034107179
-
Risk factors for longitudinal bone loss in elderly men and women: The Framingham Osteoporosis Study
-
Hannan MT, Felson DT, Dawson-Hughes B, Tucker KL, Cupples LA, et al. (2000) Risk factors for longitudinal bone loss in elderly men and women: the Framingham Osteoporosis Study. J Bone Miner Res 15: 710-720.
-
(2000)
J Bone Miner Res
, vol.15
, pp. 710-720
-
-
Hannan, M.T.1
Felson, D.T.2
Dawson-Hughes, B.3
Tucker, K.L.4
Cupples, L.A.5
-
65
-
-
33750453786
-
Convergence between bone and energy homeostases: Leptin regulation of bone mass
-
Karsenty G (2006) Convergence between bone and energy homeostases: leptin regulation of bone mass. Cell Metab 4: 341-348.
-
(2006)
Cell Metab
, vol.4
, pp. 341-348
-
-
Karsenty, G.1
-
66
-
-
34547690686
-
Endocrine regulation of energy metabolism by the skeleton
-
Lee NK, Sowa H, Hinoi E, Ferron M, Ahn JD, et al. (2007) Endocrine regulation of energy metabolism by the skeleton. Cell 130: 456-469.
-
(2007)
Cell
, vol.130
, pp. 456-469
-
-
Lee, N.K.1
Sowa, H.2
Hinoi, E.3
Ferron, M.4
Ahn, J.D.5
-
67
-
-
1842454974
-
Specification of vertebral identity is coupled to Notch signalling and the segmentation clock
-
Cordes R, Schuster-Gossler K, Serth K, Gossler A (2004) Specification of vertebral identity is coupled to Notch signalling and the segmentation clock. Development 131: 1221-1233.
-
(2004)
Development
, vol.131
, pp. 1221-1233
-
-
Cordes, R.1
Schuster-Gossler, K.2
Serth, K.3
Gossler, A.4
-
68
-
-
0032933351
-
Siah-1 N-terminal RING domain is required for proteolysis function, and C-terminal sequences regulate oligomerization and binding to target proteins
-
Hu G, Fearon ER (1999) Siah-1 N-terminal RING domain is required for proteolysis function, and C-terminal sequences regulate oligomerization and binding to target proteins. Mol Cell Biol 19: 724-732.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 724-732
-
-
Hu, G.1
Fearon, E.R.2
-
69
-
-
0038070064
-
Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1
-
Okabe H, Satoh S, Furukawa Y, Kato T, Hasegawa S, et al. (2003) Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1. Cancer Res 63: 3043-3048.
-
(2003)
Cancer Res
, vol.63
, pp. 3043-3048
-
-
Okabe, H.1
Satoh, S.2
Furukawa, Y.3
Kato, T.4
Hasegawa, S.5
-
70
-
-
0032525309
-
p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: Suppression by BAG-1
-
Matsuzawa S, Takayama S, Froesch BA, Zapata JM, Reed JC (1998) p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: suppression by BAG-1. Embo J 17: 2736-2747.
-
(1998)
Embo J
, vol.17
, pp. 2736-2747
-
-
Matsuzawa, S.1
Takayama, S.2
Froesch, B.A.3
Zapata, J.M.4
Reed, J.C.5
-
71
-
-
0035909894
-
Siah-1 binds and regulates the function of Numb
-
Susini L, Passer BJ, Amzallag-Elbaz N, Juven-Gershon T, Prieur S, et al. (2001) Siah-1 binds and regulates the function of Numb. Proc Natl Acad Sci U S A 98: 15067-15072.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 15067-15072
-
-
Susini, L.1
Passer, B.J.2
Amzallag-Elbaz, N.3
Juven-Gershon, T.4
Prieur, S.5
-
72
-
-
11244351579
-
Function and regulation of cullin-RING ubiquitin ligases
-
Petroski MD, Deshaies RJ (2005) Function and regulation of cullin-RING ubiquitin ligases. Nat Rev Mol Cell Biol 6: 9-20.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 9-20
-
-
Petroski, M.D.1
Deshaies, R.J.2
-
73
-
-
27644561755
-
Hypoxia requires notch signaling to maintain the undifferentiated cell state
-
Gustafsson MV, Zheng X, Pereira T, Gradin K, Jin S, et al. (2005) Hypoxia requires notch signaling to maintain the undifferentiated cell state. Dev Cell 9: 617-628.
-
(2005)
Dev Cell
, vol.9
, pp. 617-628
-
-
Gustafsson, M.V.1
Zheng, X.2
Pereira, T.3
Gradin, K.4
Jin, S.5
-
74
-
-
33646471404
-
Hypoxia-regulated differentiation: Let's step it up a Notch
-
Sainson RC, Harris AL (2006) Hypoxia-regulated differentiation: let's step it up a Notch. Trends Mol Med 12: 141-143.
-
(2006)
Trends Mol Med
, vol.12
, pp. 141-143
-
-
Sainson, R.C.1
Harris, A.L.2
-
75
-
-
0037343426
-
A review and comparison of the murine alpha1-antitrypsin and alpha1-antichymotrypsin multigene clusters with the human clade A serpins
-
Forsyth S, Horvath A, Coughlin P (2003) A review and comparison of the murine alpha1-antitrypsin and alpha1-antichymotrypsin multigene clusters with the human clade A serpins. Genomics 81: 336-345.
-
(2003)
Genomics
, vol.81
, pp. 336-345
-
-
Forsyth, S.1
Horvath, A.2
Coughlin, P.3
-
76
-
-
0035115958
-
Novel roles of kallistatin, a specific tissue kallikrein inhibitor, in vascular remodeling
-
Chao J, Miao RQ, Chen V, Chen LM, Chao L (2001) Novel roles of kallistatin, a specific tissue kallikrein inhibitor, in vascular remodeling. Biol Chem 382: 15-21.
-
(2001)
Biol Chem
, vol.382
, pp. 15-21
-
-
Chao, J.1
Miao, R.Q.2
Chen, V.3
Chen, L.M.4
Chao, L.5
-
77
-
-
42349108155
-
Salutary effect of kallistatin in salt-induced renal injury, inflammation, and fibrosis via antioxidative stress
-
Shen B, Hagiwara M, Yao YY, Chao L, Chao J (2008) Salutary effect of kallistatin in salt-induced renal injury, inflammation, and fibrosis via antioxidative stress. Hypertension 51: 1358-1365.
-
(2008)
Hypertension
, vol.51
, pp. 1358-1365
-
-
Shen, B.1
Hagiwara, M.2
Yao, Y.Y.3
Chao, L.4
Chao, J.5
-
78
-
-
41649105534
-
Wnt/Notch signalling and information processing during development
-
Hayward P, Kalmar T, Arias AM (2008) Wnt/Notch signalling and information processing during development. Development 135: 411-424.
-
(2008)
Development
, vol.135
, pp. 411-424
-
-
Hayward, P.1
Kalmar, T.2
Arias, A.M.3
-
79
-
-
67650653925
-
Metabolic phenotyping of mouse mutants in the German Mouse Clinic
-
Elvert R, Ehrhardt N, Taube M, Klingenspor M, Gailus-Durner V, et al. (2006) Metabolic phenotyping of mouse mutants in the German Mouse Clinic. Integrative Zoology 1: 122-125.
-
(2006)
Integrative Zoology
, vol.1
, pp. 122-125
-
-
Elvert, R.1
Ehrhardt, N.2
Taube, M.3
Klingenspor, M.4
Gailus-Durner, V.5
-
80
-
-
34247335031
-
Power matters in closing the phenotyping gap
-
Meyer CW, Elvert R, Scherag A, Ehrhardt N, Gailus-Durner V, et al. (2007) Power matters in closing the phenotyping gap. Naturwissenschaften 94: 401-406.
-
(2007)
Naturwissenschaften
, vol.94
, pp. 401-406
-
-
Meyer, C.W.1
Elvert, R.2
Scherag, A.3
Ehrhardt, N.4
Gailus-Durner, V.5
-
81
-
-
33846574695
-
Expanding the body mass range: Associations between BMR and tissue morphology in wild type and mutant dwarf mice (David mice)
-
Meyer CW, Neubronner J, Rozman J, Stumm G, Osanger A, et al. (2007) Expanding the body mass range: associations between BMR and tissue morphology in wild type and mutant dwarf mice (David mice). J Comp Physiol [B] 177: 183-192.
-
(2007)
J Comp Physiol
, vol.177
, Issue.B
, pp. 183-192
-
-
Meyer, C.W.1
Neubronner, J.2
Rozman, J.3
Stumm, G.4
Osanger, A.5
-
82
-
-
0000076488
-
The effect of apparatus, extraction time, and solvent type on lipid extractions of snow geese
-
Dobush GR, Ankney CD, Krementz DG (1985) The effect of apparatus, extraction time, and solvent type on lipid extractions of snow geese. Canadian Journal of Zoology 63: 1917-1920.
-
(1985)
Canadian Journal of Zoology
, vol.63
, pp. 1917-1920
-
-
Dobush, G.R.1
Ankney, C.D.2
Krementz, D.G.3
-
83
-
-
52049125697
-
Sighted C3H mice - a tool for analysing the influence of vision on mouse behaviour?
-
Hoelter SM, Dalke C, Kallnik M, Becker L, Horsch M, et al. (2008) "Sighted C3H" mice - a tool for analysing the influence of vision on mouse behaviour? Front Biosci 13: 5810-5823.
-
(2008)
Front Biosci
, vol.13
, pp. 5810-5823
-
-
Hoelter, S.M.1
Dalke, C.2
Kallnik, M.3
Becker, L.4
Horsch, M.5
-
84
-
-
0034425715
-
Genome-wide, large-scale production of mutant mice by ENU mutagenesis
-
Hrabe de Angelis M, Flaswinkel H, Fuchs H, Rathkolb B, Soewarto D, et al. (2000) Genome-wide, large-scale production of mutant mice by ENU mutagenesis. Nat Genet 25: 444-447.
-
(2000)
Nat Genet
, vol.25
, pp. 444-447
-
-
Hrabe de Angelis, M.1
Flaswinkel, H.2
Fuchs, H.3
Rathkolb, B.4
Soewarto, D.5
-
85
-
-
32144464546
-
Genotype-specific environmental impact on the variance of blood values in inbred and F1 hybrid mice
-
Klempt M, Rathkolb B, Fuchs E, Hrabé de Angelis M, Wolf E, et al. (2006) Genotype-specific environmental impact on the variance of blood values in inbred and F1 hybrid mice. Mamm Genome 17: 93-102.
-
(2006)
Mamm Genome
, vol.17
, pp. 93-102
-
-
Klempt, M.1
Rathkolb, B.2
Fuchs, E.3
Hrabé de Angelis, M.4
Wolf, E.5
-
86
-
-
34249024263
-
Mouse phenotyping: Immunology
-
Hrabe de Angelis M, Chambon P, Brown SD, eds, Weinheim: Whiley-VCH Verlag. pp
-
Kalaydjiev S, Franz T, Busch DH (2006) Mouse phenotyping: immunology. In: Hrabe de Angelis M, Chambon P, Brown SD, eds. Standards of Mouse Models Phenotyping. Weinheim: Whiley-VCH Verlag. pp 237-252.
-
(2006)
Standards of Mouse Models Phenotyping
, pp. 237-252
-
-
Kalaydjiev, S.1
Franz, T.2
Busch, D.H.3
-
87
-
-
0033860044
-
Screening for dysmorphological abnormalities - a powerful tool to isolate new mouse mutants
-
Fuchs H, Schughart K, Wolf E, Balling R, Hrabe de Angelis M (2000) Screening for dysmorphological abnormalities - a powerful tool to isolate new mouse mutants. Mamm Genome 11: 528-530.
-
(2000)
Mamm Genome
, vol.11
, pp. 528-530
-
-
Fuchs, H.1
Schughart, K.2
Wolf, E.3
Balling, R.4
Hrabe de Angelis, M.5
-
88
-
-
0033818954
-
A concise guide to cDNA microarray analysis
-
passim
-
Hegde P, Qi R, Abernathy K, Gay C, Dharap S, et al. (2000) A concise guide to cDNA microarray analysis. Biotechniques 29: 548-550, 552-544, 556 passim.
-
(2000)
Biotechniques
, vol.29
-
-
Hegde, P.1
Qi, R.2
Abernathy, K.3
Gay, C.4
Dharap, S.5
-
89
-
-
0037311919
-
TM4: A free, open-source system for microarray data management and analysis
-
Saeed AI, Sharov V, White J, Li J, Liang W, et al. (2003) TM4: a free, open-source system for microarray data management and analysis. Biotechniques 34: 374-378.
-
(2003)
Biotechniques
, vol.34
, pp. 374-378
-
-
Saeed, A.I.1
Sharov, V.2
White, J.3
Li, J.4
Liang, W.5
-
90
-
-
36448991500
-
-
Larkin MA, Blackshields G, Brown NP, Chenna R, McGettigan PA, et al, 2007 Clustal W and Clustal X version 2.0. Bioinformatics 23: 2947-2948
-
Larkin MA, Blackshields G, Brown NP, Chenna R, McGettigan PA, et al. (2007) Clustal W and Clustal X version 2.0. Bioinformatics 23: 2947-2948.
-
-
-
|