-
1
-
-
4344644432
-
Body fat, leptin, and hypothalamic amenorrhea
-
Ahima R.S. Body fat, leptin, and hypothalamic amenorrhea. N. Engl. J. Med. 351 (2004) 959-962
-
(2004)
N. Engl. J. Med.
, vol.351
, pp. 959-962
-
-
Ahima, R.S.1
-
4
-
-
0034802121
-
Absence of cocaine- and amphetamine-regulated transcript results in obesity in mice fed a high caloric diet
-
Asnicar M.A., Smith D.P., Yang D.D., Heiman M.L., Fox N., Chen Y.F., Hsiung H.M., and Koster A. Absence of cocaine- and amphetamine-regulated transcript results in obesity in mice fed a high caloric diet. Endocrinology 142 (2001) 4394-4400
-
(2001)
Endocrinology
, vol.142
, pp. 4394-4400
-
-
Asnicar, M.A.1
Smith, D.P.2
Yang, D.D.3
Heiman, M.L.4
Fox, N.5
Chen, Y.F.6
Hsiung, H.M.7
Koster, A.8
-
5
-
-
0031623306
-
The MONA LISA hypothesis in the time of leptin
-
Bray G.A., and York D.A. The MONA LISA hypothesis in the time of leptin. Recent Prog. Horm. Res. 53 (1998) 95-117
-
(1998)
Recent Prog. Horm. Res.
, vol.53
, pp. 95-117
-
-
Bray, G.A.1
York, D.A.2
-
6
-
-
0033546002
-
Targeted disruption of the beta2 adrenergic receptor gene
-
Chruscinski A.J., Rohrer D.K., Schauble E., Desai K.H., Bernstein D., and Kobilka B.K. Targeted disruption of the beta2 adrenergic receptor gene. J. Biol. Chem. 274 (1999) 16694-16700
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 16694-16700
-
-
Chruscinski, A.J.1
Rohrer, D.K.2
Schauble, E.3
Desai, K.H.4
Bernstein, D.5
Kobilka, B.K.6
-
7
-
-
0002627493
-
Magnitude and impact of osteoporosis and fractures
-
Marcus R., Feldman D., and Kelsey J. (Eds), Academic Press, San Diego
-
Cooper C., and Melton L.J.I. Magnitude and impact of osteoporosis and fractures. In: Marcus R., Feldman D., and Kelsey J. (Eds). Osteoporosis (1996), Academic Press, San Diego 419-434
-
(1996)
Osteoporosis
, pp. 419-434
-
-
Cooper, C.1
Melton, L.J.I.2
-
8
-
-
18744376564
-
Leptin directly regulates bone cell function in vitro and reduces bone fragility in vivo
-
Cornish J., Callon K.E., Bava U., Lin C., Naot D., Hill B.L., Grey A.B., Broom N., Myers D.E., Nicholson G.C., and Reid I.R. Leptin directly regulates bone cell function in vitro and reduces bone fragility in vivo. J. Endocrinol. 175 (2002) 405-415
-
(2002)
J. Endocrinol.
, vol.175
, pp. 405-415
-
-
Cornish, J.1
Callon, K.E.2
Bava, U.3
Lin, C.4
Naot, D.5
Hill, B.L.6
Grey, A.B.7
Broom, N.8
Myers, D.E.9
Nicholson, G.C.10
Reid, I.R.11
-
9
-
-
0032506010
-
Dissociation between bone resorption and bone formation in osteopenic transgenic mice
-
Corral D.A., Amling M., Priemel M., Loyer E., Fuchs S., Ducy P., Baron R., and Karsenty G. Dissociation between bone resorption and bone formation in osteopenic transgenic mice. Proc. Natl. Acad. Sci. USA 95 (1998) 13835-13840
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13835-13840
-
-
Corral, D.A.1
Amling, M.2
Priemel, M.3
Loyer, E.4
Fuchs, S.5
Ducy, P.6
Baron, R.7
Karsenty, G.8
-
10
-
-
30644473109
-
Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis
-
Dhillon H., Zigman J.M., Ye C., Lee C.E., McGovern R.A., Tang V., Kenny C.D., Christiansen L.M., White R.D., Edelstein E.A., et al. Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis. Neuron 49 (2006) 191-203
-
(2006)
Neuron
, vol.49
, pp. 191-203
-
-
Dhillon, H.1
Zigman, J.M.2
Ye, C.3
Lee, C.E.4
McGovern, R.A.5
Tang, V.6
Kenny, C.D.7
Christiansen, L.M.8
White, R.D.9
Edelstein, E.A.10
-
11
-
-
0141737573
-
Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass
-
Ducy P., Amling M., Takeda S., Priemel M., Schilling A.F., Beil F.T., Shen J., Vinson C., Rueger J.M., and Karsenty G. Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass. Cell 100 (2000) 197-207
-
(2000)
Cell
, vol.100
, pp. 197-207
-
-
Ducy, P.1
Amling, M.2
Takeda, S.3
Priemel, M.4
Schilling, A.F.5
Beil, F.T.6
Shen, J.7
Vinson, C.8
Rueger, J.M.9
Karsenty, G.10
-
12
-
-
15844384047
-
Leptin regulation of bone resorption by the sympathetic nervous system and CART
-
Elefteriou F., Ahn J.D., Takeda S., Starbuck M., Yang X., Liu X., Kondo H., Richards W.G., Bannon T.W., Noda M., et al. Leptin regulation of bone resorption by the sympathetic nervous system and CART. Nature 434 (2005) 514-520
-
(2005)
Nature
, vol.434
, pp. 514-520
-
-
Elefteriou, F.1
Ahn, J.D.2
Takeda, S.3
Starbuck, M.4
Yang, X.5
Liu, X.6
Kondo, H.7
Richards, W.G.8
Bannon, T.W.9
Noda, M.10
-
13
-
-
12144288193
-
Serum leptin level is a regulator of bone mass
-
Elefteriou F., Takeda S., Ebihara K., Magre J., Patano N., Kim C.A., Ogawa Y., Liu X., Ware S.M., Craigen W.J., et al. Serum leptin level is a regulator of bone mass. Proc. Natl. Acad. Sci. USA 101 (2004) 3258-3263
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3258-3263
-
-
Elefteriou, F.1
Takeda, S.2
Ebihara, K.3
Magre, J.4
Patano, N.5
Kim, C.A.6
Ogawa, Y.7
Liu, X.8
Ware, S.M.9
Craigen, W.J.10
-
14
-
-
0032436307
-
Leptin activates hypothalamic CART neurons projecting to the spinal cord
-
Elias C.F., Lee C., Kelly J., Aschkenasi C., Ahima R.S., Couceyro P.R., Kuhar M.J., Saper C.B., and Elmquist J.K. Leptin activates hypothalamic CART neurons projecting to the spinal cord. Neuron 21 (1998) 1375-1385
-
(1998)
Neuron
, vol.21
, pp. 1375-1385
-
-
Elias, C.F.1
Lee, C.2
Kelly, J.3
Aschkenasi, C.4
Ahima, R.S.5
Couceyro, P.R.6
Kuhar, M.J.7
Saper, C.B.8
Elmquist, J.K.9
-
15
-
-
0343953074
-
Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency
-
Farooqi I.S., Yeo G.S., Keogh J.M., Aminian S., Jebb S.A., Butler G., Cheetham T., and O'Rahilly S. Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency. J. Clin. Invest. 106 (2000) 271-279
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 271-279
-
-
Farooqi, I.S.1
Yeo, G.S.2
Keogh, J.M.3
Aminian, S.4
Jebb, S.A.5
Butler, G.6
Cheetham, T.7
O'Rahilly, S.8
-
16
-
-
24144459585
-
The molecular clock mediates leptin-regulated bone formation
-
Fu L., Patel M.S., Bradley A., Wagner E.F., and Karsenty G. The molecular clock mediates leptin-regulated bone formation. Cell 122 (2005) 803-815
-
(2005)
Cell
, vol.122
, pp. 803-815
-
-
Fu, L.1
Patel, M.S.2
Bradley, A.3
Wagner, E.F.4
Karsenty, G.5
-
17
-
-
29144471169
-
Obesity susceptibility CART gene polymorphism contributes to bone remodeling in postmenopausal women
-
Guerardel A., Tanko L.B., Boutin P., Christiansen C., and Froguel P. Obesity susceptibility CART gene polymorphism contributes to bone remodeling in postmenopausal women. Osteoporos. Int. 17 (2006) 156-157
-
(2006)
Osteoporos. Int.
, vol.17
, pp. 156-157
-
-
Guerardel, A.1
Tanko, L.B.2
Boutin, P.3
Christiansen, C.4
Froguel, P.5
-
19
-
-
0030889192
-
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
-
Huszar D., Lynch C.A., Fairchild-Huntress V., Dunmore J.H., Fang Q., Berkemeier L.R., Gu W., Kesterson R.A., Boston B.A., Cone R.D., et al. Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 88 (1997) 131-141
-
(1997)
Cell
, vol.88
, pp. 131-141
-
-
Huszar, D.1
Lynch, C.A.2
Fairchild-Huntress, V.3
Dunmore, J.H.4
Fang, Q.5
Berkemeier, L.R.6
Gu, W.7
Kesterson, R.A.8
Boston, B.A.9
Cone, R.D.10
-
20
-
-
0035971432
-
AP-1 in mouse development and tumorigenesis
-
Jochum W., Passegue E., and Wagner E.F. AP-1 in mouse development and tumorigenesis. Oncogene 20 (2001) 2401-2412
-
(2001)
Oncogene
, vol.20
, pp. 2401-2412
-
-
Jochum, W.1
Passegue, E.2
Wagner, E.F.3
-
21
-
-
0036225281
-
Reaching a genetic and molecular understanding of skeletal development
-
Karsenty G., and Wagner E.F. Reaching a genetic and molecular understanding of skeletal development. Dev. Cell 2 (2002) 389-406
-
(2002)
Dev. Cell
, vol.2
, pp. 389-406
-
-
Karsenty, G.1
Wagner, E.F.2
-
22
-
-
0032492893
-
Hypothalamic CART is a new anorectic peptide regulated by leptin
-
Kristensen P., Judge M.E., Thim L., Ribel U., Christjansen K.N., Wulff B.S., Clausen J.T., Jensen P.B., Madsen O.D., Vrang N., et al. Hypothalamic CART is a new anorectic peptide regulated by leptin. Nature 393 (1998) 72-76
-
(1998)
Nature
, vol.393
, pp. 72-76
-
-
Kristensen, P.1
Judge, M.E.2
Thim, L.3
Ribel, U.4
Christjansen, K.N.5
Wulff, B.S.6
Clausen, J.T.7
Jensen, P.B.8
Madsen, O.D.9
Vrang, N.10
-
23
-
-
0031798284
-
Reflex sympathetic dystrophy: facts and hypotheses
-
Kurvers H.A. Reflex sympathetic dystrophy: facts and hypotheses. Vasc. Med. 3 (1998) 207-214
-
(1998)
Vasc. Med.
, vol.3
, pp. 207-214
-
-
Kurvers, H.A.1
-
24
-
-
4544362674
-
Mammalian circadian biology: elucidating genome-wide levels of temporal organization
-
Lowrey P.L., and Takahashi J.S. Mammalian circadian biology: elucidating genome-wide levels of temporal organization. Annu. Rev. Genomics Hum. Genet. 5 (2004) 407-441
-
(2004)
Annu. Rev. Genomics Hum. Genet.
, vol.5
, pp. 407-441
-
-
Lowrey, P.L.1
Takahashi, J.S.2
-
25
-
-
23044445737
-
Leptin modulates both resorption and formation while preventing disuse-induced bone loss in tail-suspended female rats
-
Martin A., de Vittoris R., David V., Moraes R., Begeot M., Lafage-Proust M.H., Alexandre C., Vico L., and Thomas T. Leptin modulates both resorption and formation while preventing disuse-induced bone loss in tail-suspended female rats. Endocrinology 146 (2005) 3652-3659
-
(2005)
Endocrinology
, vol.146
, pp. 3652-3659
-
-
Martin, A.1
de Vittoris, R.2
David, V.3
Moraes, R.4
Begeot, M.5
Lafage-Proust, M.H.6
Alexandre, C.7
Vico, L.8
Thomas, T.9
-
26
-
-
0036889795
-
Time after time: inputs to and outputs from the mammalian circadian oscillators
-
Morse D., and Sassone-Corsi P. Time after time: inputs to and outputs from the mammalian circadian oscillators. Trends Neurosci. 25 (2002) 632-637
-
(2002)
Trends Neurosci.
, vol.25
, pp. 632-637
-
-
Morse, D.1
Sassone-Corsi, P.2
-
27
-
-
0033601239
-
Photic induction of mPer1 and mPer2 in cry-deficient mice lacking a biological clock
-
Okamura H., Miyake S., Sumi Y., Yamaguchi S., Yasui A., Muijtjens M., Hoeijmakers J.H., and van der Horst G.T. Photic induction of mPer1 and mPer2 in cry-deficient mice lacking a biological clock. Science 286 (1999) 2531-2534
-
(1999)
Science
, vol.286
, pp. 2531-2534
-
-
Okamura, H.1
Miyake, S.2
Sumi, Y.3
Yamaguchi, S.4
Yasui, A.5
Muijtjens, M.6
Hoeijmakers, J.H.7
van der Horst, G.T.8
-
29
-
-
1542331341
-
Beta-adrenergic blockers reduce the risk of fracture partly by increasing bone mineral density: Geelong Osteoporosis Study
-
Pasco J.A., Henry M.J., Sanders K.M., Kotowicz M.A., Seeman E., and Nicholson G.C. Beta-adrenergic blockers reduce the risk of fracture partly by increasing bone mineral density: Geelong Osteoporosis Study. J. Bone Miner. Res. 19 (2004) 19-24
-
(2004)
J. Bone Miner. Res.
, vol.19
, pp. 19-24
-
-
Pasco, J.A.1
Henry, M.J.2
Sanders, K.M.3
Kotowicz, M.A.4
Seeman, E.5
Nicholson, G.C.6
-
31
-
-
0002304218
-
Parathyroid hormone and parathyroid hormone-related peptide in calcium homeostasis, bone metabolism and bone development: the proteins, their genes and receptors
-
Press A. (Ed), Academic Press, San Diego
-
Potts J.T., and Juppner H. Parathyroid hormone and parathyroid hormone-related peptide in calcium homeostasis, bone metabolism and bone development: the proteins, their genes and receptors. In: Press A. (Ed). Metabolic Bone Disease and Clinically Related Disorders (1998), Academic Press, San Diego 52-94
-
(1998)
Metabolic Bone Disease and Clinically Related Disorders
, pp. 52-94
-
-
Potts, J.T.1
Juppner, H.2
-
32
-
-
22044443714
-
Clinical practice. Screening for osteoporosis
-
Raisz L.G. Clinical practice. Screening for osteoporosis. N. Engl. J. Med. 353 (2005) 164-171
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 164-171
-
-
Raisz, L.G.1
-
33
-
-
32944477369
-
Treatment with beta-blockers, ACE inhibitors, and calcium-channel blockers is associated with a reduced fracture risk: a nationwide case-control study
-
Rejnmark L., Vestergaard P., and Mosekilde L. Treatment with beta-blockers, ACE inhibitors, and calcium-channel blockers is associated with a reduced fracture risk: a nationwide case-control study. J. Hypertens. 24 (2006) 581-589
-
(2006)
J. Hypertens.
, vol.24
, pp. 581-589
-
-
Rejnmark, L.1
Vestergaard, P.2
Mosekilde, L.3
-
34
-
-
0037194790
-
Coordination of circadian timing in mammals
-
Reppert S.M., and Weaver D.R. Coordination of circadian timing in mammals. Nature 418 (2002) 935-941
-
(2002)
Nature
, vol.418
, pp. 935-941
-
-
Reppert, S.M.1
Weaver, D.R.2
-
35
-
-
0031955217
-
A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men
-
Riggs B.L., Khosla S., and Melton III L.J. A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men. J. Bone Miner. Res. 13 (1998) 763-773
-
(1998)
J. Bone Miner. Res.
, vol.13
, pp. 763-773
-
-
Riggs, B.L.1
Khosla, S.2
Melton III, L.J.3
-
37
-
-
0034284550
-
Therapeutic approaches to bone diseases
-
Rodan G.A., and Martin T.J. Therapeutic approaches to bone diseases. Science 289 (2000) 1508-1514
-
(2000)
Science
, vol.289
, pp. 1508-1514
-
-
Rodan, G.A.1
Martin, T.J.2
-
38
-
-
15044341917
-
Cellular oscillators: rhythmic gene expression and metabolism
-
Schibler U., and Naef F. Cellular oscillators: rhythmic gene expression and metabolism. Curr. Opin. Cell Biol. 17 (2005) 223-229
-
(2005)
Curr. Opin. Cell Biol.
, vol.17
, pp. 223-229
-
-
Schibler, U.1
Naef, F.2
-
40
-
-
0013880636
-
Diurnal periodicity in the metabolic activity of bone tissue
-
Simmons D.J., and Nichols Jr. G. Diurnal periodicity in the metabolic activity of bone tissue. Am. J. Physiol. 210 (1966) 411-418
-
(1966)
Am. J. Physiol.
, vol.210
, pp. 411-418
-
-
Simmons, D.J.1
Nichols Jr., G.2
-
41
-
-
0035936764
-
Obesity and the regulation of energy balance
-
Spiegelman B.M., and Flier J.S. Obesity and the regulation of energy balance. Cell 104 (2001) 531-543
-
(2001)
Cell
, vol.104
, pp. 531-543
-
-
Spiegelman, B.M.1
Flier, J.S.2
-
42
-
-
0036847619
-
Leptin regulates bone formation via the sympathetic nervous system
-
Takeda S., Elefteriou F., Levasseur R., Liu X., Zhao L., Parker K.L., Armstrong D., Ducy P., and Karsenty G. Leptin regulates bone formation via the sympathetic nervous system. Cell 111 (2002) 305-317
-
(2002)
Cell
, vol.111
, pp. 305-317
-
-
Takeda, S.1
Elefteriou, F.2
Levasseur, R.3
Liu, X.4
Zhao, L.5
Parker, K.L.6
Armstrong, D.7
Ducy, P.8
Karsenty, G.9
-
43
-
-
2442654859
-
Identification and expression cloning of a leptin receptor, OB-R
-
Tartaglia L.A., Dembski M., Weng X., Deng N., Culpepper J., Devos R., Richards G.J., Campfield L.A., Clark F.T., Deeds J., et al. Identification and expression cloning of a leptin receptor, OB-R. Cell 83 (1995) 1263-1271
-
(1995)
Cell
, vol.83
, pp. 1263-1271
-
-
Tartaglia, L.A.1
Dembski, M.2
Weng, X.3
Deng, N.4
Culpepper, J.5
Devos, R.6
Richards, G.J.7
Campfield, L.A.8
Clark, F.T.9
Deeds, J.10
-
44
-
-
0043267732
-
Genetic regulation of osteoclast development and function
-
Teitelbaum S.L., and Ross F.P. Genetic regulation of osteoclast development and function. Nat. Rev. Genet. 4 (2003) 638-649
-
(2003)
Nat. Rev. Genet.
, vol.4
, pp. 638-649
-
-
Teitelbaum, S.L.1
Ross, F.P.2
-
45
-
-
0030782406
-
Impaired maternal behavior in mice lacking norepinephrine and epinephrine
-
Thomas S.A., and Palmiter R.D. Impaired maternal behavior in mice lacking norepinephrine and epinephrine. Cell 91 (1997) 583-592
-
(1997)
Cell
, vol.91
, pp. 583-592
-
-
Thomas, S.A.1
Palmiter, R.D.2
-
46
-
-
0032982438
-
Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes
-
Thomas T., Gori F., Khosla S., Jensen M.D., Burguera B., and Riggs B.L. Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes. Endocrinology 140 (1999) 1630-1638
-
(1999)
Endocrinology
, vol.140
, pp. 1630-1638
-
-
Thomas, T.1
Gori, F.2
Khosla, S.3
Jensen, M.D.4
Burguera, B.5
Riggs, B.L.6
-
48
-
-
0031662163
-
A frameshift mutation in human MC4R is associated with a dominant form of obesity
-
Vaisse C., Clement K., Guy-Grand B., and Froguel P. A frameshift mutation in human MC4R is associated with a dominant form of obesity. Nat. Genet. 20 (1998) 113-114
-
(1998)
Nat. Genet.
, vol.20
, pp. 113-114
-
-
Vaisse, C.1
Clement, K.2
Guy-Grand, B.3
Froguel, P.4
-
49
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., and Friedman J.M. Positional cloning of the mouse obese gene and its human homologue. Nature 372 (1994) 425-432
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
50
-
-
0035368681
-
Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock
-
Zheng B., Albrecht U., Kaasik K., Sage M., Lu W., Vaishnav S., Li Q., Sun Z.S., Eichele G., Bradley A., and Lee C.C. Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock. Cell 105 (2001) 683-694
-
(2001)
Cell
, vol.105
, pp. 683-694
-
-
Zheng, B.1
Albrecht, U.2
Kaasik, K.3
Sage, M.4
Lu, W.5
Vaishnav, S.6
Li, Q.7
Sun, Z.S.8
Eichele, G.9
Bradley, A.10
Lee, C.C.11
|