-
1
-
-
0022446921
-
Hyperalgesic response in a patient receiving high concentrations of spinal morphine
-
Ali N.M.K. Hyperalgesic response in a patient receiving high concentrations of spinal morphine. Anesthesiology 65 (1986) 449
-
(1986)
Anesthesiology
, vol.65
, pp. 449
-
-
Ali, N.M.K.1
-
2
-
-
0031646358
-
Comparison of the effects of calmidazolium, morphine and bupivacaine on N-methyl-d-aspartate- and septide-induced nociceptive behaviour
-
Alvarez-Vega M., Baamonde A., Gutierrez M., Hidalgo A., and Menendes L. Comparison of the effects of calmidazolium, morphine and bupivacaine on N-methyl-d-aspartate- and septide-induced nociceptive behaviour. Naunyn-Schmiedeberg's Arch. Pharmacol. 358 (1998) 628-634
-
(1998)
Naunyn-Schmiedeberg's Arch. Pharmacol.
, vol.358
, pp. 628-634
-
-
Alvarez-Vega, M.1
Baamonde, A.2
Gutierrez, M.3
Hidalgo, A.4
Menendes, L.5
-
3
-
-
0033135292
-
Triplicate synapses: Glia, the unacknowledged partner
-
Araque A., Parpura V., Sanzgiri R.P., and Haydon P.G. Triplicate synapses: Glia, the unacknowledged partner. Trends Neurosci. 22 (1999) 208-215
-
(1999)
Trends Neurosci.
, vol.22
, pp. 208-215
-
-
Araque, A.1
Parpura, V.2
Sanzgiri, R.P.3
Haydon, P.G.4
-
4
-
-
0032981277
-
Dynorphine A increases substance P release from trigeminal primary afferent C-fibers
-
Arcaya J.L., Cano G., Gómez G., Maixner W., and Suárez-Roca H. Dynorphine A increases substance P release from trigeminal primary afferent C-fibers. Eur. J. Pharmacol. 366 (1999) 27-34
-
(1999)
Eur. J. Pharmacol.
, vol.366
, pp. 27-34
-
-
Arcaya, J.L.1
Cano, G.2
Gómez, G.3
Maixner, W.4
Suárez-Roca, H.5
-
5
-
-
0023895008
-
Clinical experience of long-term treatment with epidural opioids-A nationwide survey
-
Arner S., Rawal N., and Gustafsson L.L. Clinical experience of long-term treatment with epidural opioids-A nationwide survey. Acta Anaesthesiol. Scand. 32 (1988) 253-259
-
(1988)
Acta Anaesthesiol. Scand.
, vol.32
, pp. 253-259
-
-
Arner, S.1
Rawal, N.2
Gustafsson, L.L.3
-
6
-
-
0028017873
-
Pharmacology of morphine and morphine-3-glucronide at opioid, excitatory amino acis, GABA and glycine binding site
-
Bartlett S.E., Dodd P.R., and Smith M.T. Pharmacology of morphine and morphine-3-glucronide at opioid, excitatory amino acis, GABA and glycine binding site. Pharmacol. Toxicol. 75 (1994) 73-81
-
(1994)
Pharmacol. Toxicol.
, vol.75
, pp. 73-81
-
-
Bartlett, S.E.1
Dodd, P.R.2
Smith, M.T.3
-
7
-
-
0027397544
-
Inositol trisphosphate and calcium signaling
-
Berridge M.J. Inositol trisphosphate and calcium signaling. Nature 361 (1993) 315-325
-
(1993)
Nature
, vol.361
, pp. 315-325
-
-
Berridge, M.J.1
-
8
-
-
0033549244
-
Loss of anti nociceptive spinal/supraspinal morphine synergy in nerve-injured rats; restoration by MK-801 or dynorphine antiserum
-
Bian D.S., Ossipov M.H., Ibrahim M., Raffa R.B., Tallarida R.J., Malan Jr. T.P., Lai J., and Porreca F. Loss of anti nociceptive spinal/supraspinal morphine synergy in nerve-injured rats; restoration by MK-801 or dynorphine antiserum. Brain Res. 831 (1999) 55-63
-
(1999)
Brain Res.
, vol.831
, pp. 55-63
-
-
Bian, D.S.1
Ossipov, M.H.2
Ibrahim, M.3
Raffa, R.B.4
Tallarida, R.J.5
Malan Jr. T.P.6
Lai, J.7
Porreca, F.8
-
9
-
-
0016802610
-
The metabolism of morphine and heroin in man
-
Boerner U., Abbott S., and Roe R.L. The metabolism of morphine and heroin in man. Drug Metab. Rev. 4 (1975) 39-73
-
(1975)
Drug Metab. Rev.
, vol.4
, pp. 39-73
-
-
Boerner, U.1
Abbott, S.2
Roe, R.L.3
-
10
-
-
28644433404
-
Activation of the ERK signaling pathway contributes naloxone-precipitated withdrawal in morphine-dependent rats
-
Cao J.L., He J.H., Ding H.L., and Zeng Y.M. Activation of the ERK signaling pathway contributes naloxone-precipitated withdrawal in morphine-dependent rats. Pain 228 (2005) 336-349
-
(2005)
Pain
, vol.228
, pp. 336-349
-
-
Cao, J.L.1
He, J.H.2
Ding, H.L.3
Zeng, Y.M.4
-
11
-
-
33746268078
-
Cross talk between nitric oxide and ERK1/2 signaling pathway in the spinal cord mediates naloxone-precipitated withdrawal in morphine-dependent rats
-
Cao J.L., Liu H.L., Wang J.K., and Zeng Y.M. Cross talk between nitric oxide and ERK1/2 signaling pathway in the spinal cord mediates naloxone-precipitated withdrawal in morphine-dependent rats. Neuropharmacology 51 (2006) 315-326
-
(2006)
Neuropharmacology
, vol.51
, pp. 315-326
-
-
Cao, J.L.1
Liu, H.L.2
Wang, J.K.3
Zeng, Y.M.4
-
12
-
-
0030859754
-
Dissociation of microglial activation and neuropathic behaviors following peripheral nerve injury in the rat
-
Colburn R.W., DeLeo J.A., Rickman A.J., Yeager M.P., Kwon P., and Hickey W.F. Dissociation of microglial activation and neuropathic behaviors following peripheral nerve injury in the rat. J. Neuroimmunol 79 (1997) 163-175
-
(1997)
J. Neuroimmunol
, vol.79
, pp. 163-175
-
-
Colburn, R.W.1
DeLeo, J.A.2
Rickman, A.J.3
Yeager, M.P.4
Kwon, P.5
Hickey, W.F.6
-
13
-
-
31344448048
-
Activation of p38 mitogen-activated protein kinase in spinal microglia mediated morphine antinociceptive tolerance
-
Cui Y., Chen Y., Zhi J.L., Guo R.X., Feng J.Q., and Chen P.X. Activation of p38 mitogen-activated protein kinase in spinal microglia mediated morphine antinociceptive tolerance. Brain Res. 1069 (2006) 235-243
-
(2006)
Brain Res.
, vol.1069
, pp. 235-243
-
-
Cui, Y.1
Chen, Y.2
Zhi, J.L.3
Guo, R.X.4
Feng, J.Q.5
Chen, P.X.6
-
14
-
-
0025788197
-
Hyperalgesia and myoclonus with intrathecal infusion of high-dose morphine
-
DeConno F., Caraceni A., Martini C., Spoldi E., Salvetti M., and Ventafridda V. Hyperalgesia and myoclonus with intrathecal infusion of high-dose morphine. Pain 47 (1991) 337-339
-
(1991)
Pain
, vol.47
, pp. 337-339
-
-
DeConno, F.1
Caraceni, A.2
Martini, C.3
Spoldi, E.4
Salvetti, M.5
Ventafridda, V.6
-
15
-
-
0026601969
-
Dynorphine increases extracellular levels of excitatory amino acids in the brain through a non-opioid mechanism
-
Faden A.I. Dynorphine increases extracellular levels of excitatory amino acids in the brain through a non-opioid mechanism. J. Neurosci. 12 (1992) 425-429
-
(1992)
J. Neurosci.
, vol.12
, pp. 425-429
-
-
Faden, A.I.1
-
16
-
-
0026724017
-
Further evidence that morphine-6β-glucronide is a more potent opioid antagonist than morphine
-
Frances B., Gout R., Monsarrat B., Cros J., and Zajac J.M. Further evidence that morphine-6β-glucronide is a more potent opioid antagonist than morphine. J. Pharmacol. Exp. Ther. 262 (1992) 25-31
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.262
, pp. 25-31
-
-
Frances, B.1
Gout, R.2
Monsarrat, B.3
Cros, J.4
Zajac, J.M.5
-
17
-
-
0033577464
-
Micloglial reactions after subcutaneous formalin injection into the rat hind paw
-
Fu K.Y., Light A.R., Matusshima G.K., and Maixner W. Micloglial reactions after subcutaneous formalin injection into the rat hind paw. Neuroscience 825 (1999) 59-67
-
(1999)
Neuroscience
, vol.825
, pp. 59-67
-
-
Fu, K.Y.1
Light, A.R.2
Matusshima, G.K.3
Maixner, W.4
-
18
-
-
0028255858
-
Carrageenan induced inflammation alters the content of i-cGMP and i-cAMP in the dorsal horn of the spinal cord
-
Garry M.G., Richardson J.D., and Hargreaves K.M. Carrageenan induced inflammation alters the content of i-cGMP and i-cAMP in the dorsal horn of the spinal cord. Brain Res. 646 (1994) 135-139
-
(1994)
Brain Res.
, vol.646
, pp. 135-139
-
-
Garry, M.G.1
Richardson, J.D.2
Hargreaves, K.M.3
-
19
-
-
0023899468
-
Myoclonic spasms following intrathecal morphine
-
Glavina M.J., and Robertshaw R. Myoclonic spasms following intrathecal morphine. Anaesthesia 43 (1988) 389-390
-
(1988)
Anaesthesia
, vol.43
, pp. 389-390
-
-
Glavina, M.J.1
Robertshaw, R.2
-
20
-
-
34249795149
-
Glial-cytokine-neuronal interactions underlying the mechanisms of persistent pain
-
Guo W., Wang H., Watanabe M., Shimizu K., Zou S., LaGraize S.C., Wei F., Dubner R., and Ren K. Glial-cytokine-neuronal interactions underlying the mechanisms of persistent pain. J. Neurosci. 27 (2007) 6006-6018
-
(2007)
J. Neurosci.
, vol.27
, pp. 6006-6018
-
-
Guo, W.1
Wang, H.2
Watanabe, M.3
Shimizu, K.4
Zou, S.5
LaGraize, S.C.6
Wei, F.7
Dubner, R.8
Ren, K.9
-
21
-
-
33646439133
-
Activated microglia contribute to the maintenance of chronic pain after spinal cord injury
-
Hains B.C., and Waxman S.G. Activated microglia contribute to the maintenance of chronic pain after spinal cord injury. J. Neurosci. 26 (2006) 4308-4317
-
(2006)
J. Neurosci.
, vol.26
, pp. 4308-4317
-
-
Hains, B.C.1
Waxman, S.G.2
-
22
-
-
0035287432
-
Glia: Listening and talking to synapse
-
Haydon P.G. Glia: Listening and talking to synapse. Nat. Rev. Neurosci. 2 (2001) 185-193
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 185-193
-
-
Haydon, P.G.1
-
23
-
-
3843103991
-
HIV-1 gp120 stimulates proinflammatory cytokine-mediated pain facilitation via activation of nitric oxide synthase-I (nNOS)
-
Holguin A., O'sConnor K.A., Biedenkapp J., Campisi J., Wieseler-Frank J., Milligan E.D., Hansen M.K., Spataro L., Maksimova E., Bravmann C., Martin D., Fleshner M., et al. HIV-1 gp120 stimulates proinflammatory cytokine-mediated pain facilitation via activation of nitric oxide synthase-I (nNOS). Pain 110 (2004) 517-530
-
(2004)
Pain
, vol.110
, pp. 517-530
-
-
Holguin, A.1
O'sConnor, K.A.2
Biedenkapp, J.3
Campisi, J.4
Wieseler-Frank, J.5
Milligan, E.D.6
Hansen, M.K.7
Spataro, L.8
Maksimova, E.9
Bravmann, C.10
Martin, D.11
Fleshner, M.12
-
24
-
-
0034130227
-
Murine models of inflammatory, neuropathic and cancer pain each generates a unique set of neurochemical changes in the spinal cord and sensory neurons
-
Honore P., Rogers S.D., Schwei M.J., Salak-Johnson J.L., Luger N.M., Sabino M.C., Clohisy D.R., and Mantyh P.W. Murine models of inflammatory, neuropathic and cancer pain each generates a unique set of neurochemical changes in the spinal cord and sensory neurons. Neuroscience 98 (2000) 585-598
-
(2000)
Neuroscience
, vol.98
, pp. 585-598
-
-
Honore, P.1
Rogers, S.D.2
Schwei, M.J.3
Salak-Johnson, J.L.4
Luger, N.M.5
Sabino, M.C.6
Clohisy, D.R.7
Mantyh, P.W.8
-
25
-
-
0141856610
-
ERK integrates PKA and PKC signaling in superficial dorsal horn neurons. I: Modulation of A-type K currents
-
Hu H., Glauner K.S., and Gereau R.W. ERK integrates PKA and PKC signaling in superficial dorsal horn neurons. I: Modulation of A-type K currents. J. Neurophysiol. 90 (2003) 1671-1679
-
(2003)
J. Neurophysiol.
, vol.90
, pp. 1671-1679
-
-
Hu, H.1
Glauner, K.S.2
Gereau, R.W.3
-
26
-
-
0032191933
-
2+ stimulation of CREB-dependent transcription and ERK nuclear translocation
-
2+ stimulation of CREB-dependent transcription and ERK nuclear translocation. Neuron 21 (1998) 869-883
-
(1998)
Neuron
, vol.21
, pp. 869-883
-
-
Impey, S.1
Obrietan, K.2
Wong, S.T.3
Poser, S.4
Yano, S.5
Wayman, G.6
Deloulme, J.C.7
Chan, G.8
Storm, D.R.9
-
27
-
-
0033136259
-
Making new concentration: Role of ERK/MAP kinase signaling in neuronal plasticity
-
Impey S., Obrietan K., and Storm D.R. Making new concentration: Role of ERK/MAP kinase signaling in neuronal plasticity. Neuron 23 (1999) 11-14
-
(1999)
Neuron
, vol.23
, pp. 11-14
-
-
Impey, S.1
Obrietan, K.2
Storm, D.R.3
-
28
-
-
7944238825
-
Cell signaling and the genesis of neuropathic pain
-
Ji R.R., and Strichartz G. Cell signaling and the genesis of neuropathic pain. Sci. STKE 252 (2004) reE14
-
(2004)
Sci. STKE
, vol.252
-
-
Ji, R.R.1
Strichartz, G.2
-
29
-
-
0035116529
-
Neuronal plasticity and signal transduction in nociceptive neurons: Implications for the initiation and maintenance of pathological pain
-
Ji R.R., and Woolf C.J. Neuronal plasticity and signal transduction in nociceptive neurons: Implications for the initiation and maintenance of pathological pain. Neurobiol. Dis. 8 (2001) 1-10
-
(2001)
Neurobiol. Dis.
, vol.8
, pp. 1-10
-
-
Ji, R.R.1
Woolf, C.J.2
-
30
-
-
0033490464
-
Nociceptive specific activation of ERK in spinal neurons contributes to pain hypersensitivity
-
Ji R.R., Baba H., Brenner G.J., and Woolf C.J. Nociceptive specific activation of ERK in spinal neurons contributes to pain hypersensitivity. Nat. Neurosci. 2 (1999) 1114-1119
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 1114-1119
-
-
Ji, R.R.1
Baba, H.2
Brenner, G.J.3
Woolf, C.J.4
-
31
-
-
0037080003
-
ERK MAP kinase activation in superficial spinal cord neurons induced prodynorphine and NK-1 upregulation and contributes to persistent inflammatory pain hypersensitivity
-
Ji R.R., Befort K., Brenner G.J., and Woolf C.J. ERK MAP kinase activation in superficial spinal cord neurons induced prodynorphine and NK-1 upregulation and contributes to persistent inflammatory pain hypersensitivity. J. Neurosci. 22 (2002) 478-485
-
(2002)
J. Neurosci.
, vol.22
, pp. 478-485
-
-
Ji, R.R.1
Befort, K.2
Brenner, G.J.3
Woolf, C.J.4
-
32
-
-
0242475309
-
Central sensitization and longterm potentiation-Do pain and memory share similar mechanism?
-
Ji R.R., Kohno T., Moore K.A., and Woolf C.J. Central sensitization and longterm potentiation-Do pain and memory share similar mechanism?. Trends Neurosci. 26 (2003) 696-705
-
(2003)
Trends Neurosci.
, vol.26
, pp. 696-705
-
-
Ji, R.R.1
Kohno, T.2
Moore, K.A.3
Woolf, C.J.4
-
33
-
-
7244226284
-
A role for proinflammatory cytokines and fractalkine in analgesia, tolerance, and subsequent pain facilitation induced by chronic intrathecal morphine
-
Jonston I.N., Milligan E.D., Wieseler-Frank J., Frank M.G., Zapata V., Campisi J., Langer S., Martin D., Green P., Fleeshner M., Leinwand L., Maier S.F., et al. A role for proinflammatory cytokines and fractalkine in analgesia, tolerance, and subsequent pain facilitation induced by chronic intrathecal morphine. J. Neurosci. 24 (2004) 7353-7365
-
(2004)
J. Neurosci.
, vol.24
, pp. 7353-7365
-
-
Jonston, I.N.1
Milligan, E.D.2
Wieseler-Frank, J.3
Frank, M.G.4
Zapata, V.5
Campisi, J.6
Langer, S.7
Martin, D.8
Green, P.9
Fleeshner, M.10
Leinwand, L.11
Maier, S.F.12
-
34
-
-
0035371317
-
Metabotropic glutamate receptor subtypes 1 and 5 are activators of extracellular signal-regulated kinase signaling required for inflammatory pain in mice
-
Karim F., Wang C.C., and Gereau R.W. Metabotropic glutamate receptor subtypes 1 and 5 are activators of extracellular signal-regulated kinase signaling required for inflammatory pain in mice. J. Neurosci. 21 (2001) 3771-3779
-
(2001)
J. Neurosci.
, vol.21
, pp. 3771-3779
-
-
Karim, F.1
Wang, C.C.2
Gereau, R.W.3
-
35
-
-
4644312225
-
Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization
-
Kawasaki Y., Kohno T., Zhuang Z.Y., Brenner G.J., Wang H., Van Der Meer C., Befort K., Woolf C.J., and Ji R.R. Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization. J. Neurosci. 24 (2004) 8310-8321
-
(2004)
J. Neurosci.
, vol.24
, pp. 8310-8321
-
-
Kawasaki, Y.1
Kohno, T.2
Zhuang, Z.Y.3
Brenner, G.J.4
Wang, H.5
Van Der Meer, C.6
Befort, K.7
Woolf, C.J.8
Ji, R.R.9
-
36
-
-
1242291761
-
Nonopioid actions of intrathecal dynorphine evoke spinal excitatory amino acids and prodstaglandin E2 release mediated by cyclooxygenase-1 and -2
-
Koetzner L., Hua X.Y., Lai J., Porreca F., and Yaksh T. Nonopioid actions of intrathecal dynorphine evoke spinal excitatory amino acids and prodstaglandin E2 release mediated by cyclooxygenase-1 and -2. J. Neurosci. 24 (2004) 1451-1458
-
(2004)
J. Neurosci.
, vol.24
, pp. 1451-1458
-
-
Koetzner, L.1
Hua, X.Y.2
Lai, J.3
Porreca, F.4
Yaksh, T.5
-
37
-
-
34047134223
-
Extracellular signal-regulated kinase (ERK) and nitric oxide synthase mediate intrathecal morphine-induced nociceptive behavior
-
Komatsu T., Sakurada C., Sasaki M., Sanai K., Tsuzuki M., Bagetta G., Sakurada S., and Sakurada T. Extracellular signal-regulated kinase (ERK) and nitric oxide synthase mediate intrathecal morphine-induced nociceptive behavior. Neuropharmacology 52 (2007) 1237-1243
-
(2007)
Neuropharmacology
, vol.52
, pp. 1237-1243
-
-
Komatsu, T.1
Sakurada, C.2
Sasaki, M.3
Sanai, K.4
Tsuzuki, M.5
Bagetta, G.6
Sakurada, S.7
Sakurada, T.8
-
38
-
-
67650253975
-
Mechanism of allodynia in mice evoked by intrathecal morphine-3-glucronide
-
Komatsu T., Akiyoshi M., Sasaki M., Sakurada C., Sakurada S., and Sakurada T. Mechanism of allodynia in mice evoked by intrathecal morphine-3-glucronide. J. Pharmacol. Sci. 103 Suppl. I (2007) 125
-
(2007)
J. Pharmacol. Sci.
, vol.103
, Issue.SUPPL. I
, pp. 125
-
-
Komatsu, T.1
Akiyoshi, M.2
Sasaki, M.3
Sakurada, C.4
Sakurada, S.5
Sakurada, T.6
-
39
-
-
67650236257
-
Involvemet of spinal cord astroglia in allodynia induced by morphine-3-glucronide
-
Komatsu T., Shiohira H., Sanai K., Sakurada C., Sakurada S., and Sakurada T. Involvemet of spinal cord astroglia in allodynia induced by morphine-3-glucronide. J. Pharmacol. Sci. 106 Suppl. I (2008) 225
-
(2008)
J. Pharmacol. Sci.
, vol.106
, Issue.SUPPL. I
, pp. 225
-
-
Komatsu, T.1
Shiohira, H.2
Sanai, K.3
Sakurada, C.4
Sakurada, S.5
Sakurada, T.6
-
40
-
-
0021816535
-
Continuous infusion of spinally administered narcotics for pain due to malignant disorder
-
Krames E.S., Gershow J., Glassberg A., Kenefick T., Lyons A., Taylor P., and Wilkie D. Continuous infusion of spinally administered narcotics for pain due to malignant disorder. Cancer 56 (1985) 696-702
-
(1985)
Cancer
, vol.56
, pp. 696-702
-
-
Krames, E.S.1
Gershow, J.2
Glassberg, A.3
Kenefick, T.4
Lyons, A.5
Taylor, P.6
Wilkie, D.7
-
41
-
-
0030879183
-
Spinally administered dynorphin A produces long-lasting allodynia: Involvement of NMDA but not opioid receptors
-
Laughlin T.M., Vanderah T.W., Lashbrook J.M., Nichols M.L., Ossipov M.H., Porreca F., and Wilcox G.L. Spinally administered dynorphin A produces long-lasting allodynia: Involvement of NMDA but not opioid receptors. Pain 72 (1997) 253-260
-
(1997)
Pain
, vol.72
, pp. 253-260
-
-
Laughlin, T.M.1
Vanderah, T.W.2
Lashbrook, J.M.3
Nichols, M.L.4
Ossipov, M.H.5
Porreca, F.6
Wilcox, G.L.7
-
42
-
-
0142188665
-
The signaling components of sensory fiber transmission involved in the activation of ERK MAP kinase in the mouse dorsal horn
-
Lever I.J., Pezet S., McMahon S.B., and Malcangio M. The signaling components of sensory fiber transmission involved in the activation of ERK MAP kinase in the mouse dorsal horn. Mol. Cell. Neurosci. 24 (2003) 259-270
-
(2003)
Mol. Cell. Neurosci.
, vol.24
, pp. 259-270
-
-
Lever, I.J.1
Pezet, S.2
McMahon, S.B.3
Malcangio, M.4
-
43
-
-
0037101970
-
Function and regulation of CREB family transcription factors in the nervous system
-
Lonze B.E., and Ginty D.D. Function and regulation of CREB family transcription factors in the nervous system. Neuron 35 (2002) 605-623
-
(2002)
Neuron
, vol.35
, pp. 605-623
-
-
Lonze, B.E.1
Ginty, D.D.2
-
44
-
-
0029948720
-
Morphine-6-O-β-d-glucronide but not morphine-3-O-β-d-glucronide binds to μ-, δ-, and κ-supecific opioid binding sites in cerebral membranes
-
Loser S.V., Meyer J., Freudenthaler S., Sattler M., Desel C., Meineke I., and Gundert Remy U. Morphine-6-O-β-d-glucronide but not morphine-3-O-β-d-glucronide binds to μ-, δ-, and κ-supecific opioid binding sites in cerebral membranes. Naunyn-Schmiedeberg's Arch. Pharmacol. 354 (1996) 192-197
-
(1996)
Naunyn-Schmiedeberg's Arch. Pharmacol.
, vol.354
, pp. 192-197
-
-
Loser, S.V.1
Meyer, J.2
Freudenthaler, S.3
Sattler, M.4
Desel, C.5
Meineke, I.6
Gundert Remy, U.7
-
45
-
-
0035783434
-
Chronic morphine exposure increases the phosphorylation of MAP kinases and the transcription factor CREB in dorsal root ganglion neurons; an in vitro and in vivo study
-
Ma W., Zheng W.H., Powell K., Jhamandas K., and Quirion R. Chronic morphine exposure increases the phosphorylation of MAP kinases and the transcription factor CREB in dorsal root ganglion neurons; an in vitro and in vivo study. Eur. J. Neurosci. 14 (2001) 1091-1104
-
(2001)
Eur. J. Neurosci.
, vol.14
, pp. 1091-1104
-
-
Ma, W.1
Zheng, W.H.2
Powell, K.3
Jhamandas, K.4
Quirion, R.5
-
46
-
-
0034193926
-
Extraterritorial neuropathic pain correlates with multisegmental elevation of spinal dynorphin in nerve-injured rats
-
Malan T.P., Ossipov M.H., Gardell L.R., Ibrahim M., Bian D., Lai J., and Porreca F. Extraterritorial neuropathic pain correlates with multisegmental elevation of spinal dynorphin in nerve-injured rats. Pain 86 (2000) 185-194
-
(2000)
Pain
, vol.86
, pp. 185-194
-
-
Malan, T.P.1
Ossipov, M.H.2
Gardell, L.R.3
Ibrahim, M.4
Bian, D.5
Lai, J.6
Porreca, F.7
-
48
-
-
0242384719
-
Regulation of gene expression and cocaine reward by CREB and Delta FosB
-
McClung C.A., and Nestler E.J. Regulation of gene expression and cocaine reward by CREB and Delta FosB. Nat. Neurosci. 6 (2003) 1208-1215
-
(2003)
Nat. Neurosci.
, vol.6
, pp. 1208-1215
-
-
McClung, C.A.1
Nestler, E.J.2
-
49
-
-
0027502194
-
Nitric oxide (NO) and nociceptive processing in the spinal cord
-
Meller S.T., and Gebhart G.F. Nitric oxide (NO) and nociceptive processing in the spinal cord. Pain 52 (1993) 127-136
-
(1993)
Pain
, vol.52
, pp. 127-136
-
-
Meller, S.T.1
Gebhart, G.F.2
-
50
-
-
0028027868
-
The possible role of glia in nociceptive processing and hyperalgesia in the spinal cord of the rat
-
Meller S.T., Dykstra C., Grzybycki D., Murphy S., and Gebhart G.F. The possible role of glia in nociceptive processing and hyperalgesia in the spinal cord of the rat. Neuropharmacology 33 (1994) 1471-1478
-
(1994)
Neuropharmacology
, vol.33
, pp. 1471-1478
-
-
Meller, S.T.1
Dykstra, C.2
Grzybycki, D.3
Murphy, S.4
Gebhart, G.F.5
-
51
-
-
0035871357
-
Intrathecal HIV-1 envelope glycoprotein gp120 induces enhanced pain states mediated by spinal cord proinflammatory cytokines
-
Milligan E.D., O's Connor K.A., Nguyen K.T., Armstrong C.B., Twining C., Gaykema R.P., Holguin A., Martin D., Maier S.F., and Watkins L.R. Intrathecal HIV-1 envelope glycoprotein gp120 induces enhanced pain states mediated by spinal cord proinflammatory cytokines. J. Neurosci. 21 (2001) 2808-2819
-
(2001)
J. Neurosci.
, vol.21
, pp. 2808-2819
-
-
Milligan, E.D.1
O's Connor, K.A.2
Nguyen, K.T.3
Armstrong, C.B.4
Twining, C.5
Gaykema, R.P.6
Holguin, A.7
Martin, D.8
Maier, S.F.9
Watkins, L.R.10
-
52
-
-
47949133637
-
Glycinergic mediation of tactile allodynia induced by platelet-activating factor (PAF) through glutamate-NO-cyclic GMP signalling in spinal cord in mice
-
Morita K., Kitayama T., Morioka N., and Dohi T. Glycinergic mediation of tactile allodynia induced by platelet-activating factor (PAF) through glutamate-NO-cyclic GMP signalling in spinal cord in mice. Pain 138 (2008) 525-536
-
(2008)
Pain
, vol.138
, pp. 525-536
-
-
Morita, K.1
Kitayama, T.2
Morioka, N.3
Dohi, T.4
-
53
-
-
0041346211
-
Rap1 couples camp signaling to a distinct pool of p42/44MAPK regulating excitability, synaptic plasticity, learning, and memory
-
Morozov A., Muzzio I.A., Bourtchouladze R., Van-strien N., Lapidus K., Yin D., Winder D.G., Adams J.P., Sweatt J.D., and Kandel E.R. Rap1 couples camp signaling to a distinct pool of p42/44MAPK regulating excitability, synaptic plasticity, learning, and memory. Neuron 39 (2003) 309-325
-
(2003)
Neuron
, vol.39
, pp. 309-325
-
-
Morozov, A.1
Muzzio, I.A.2
Bourtchouladze, R.3
Van-strien, N.4
Lapidus, K.5
Yin, D.6
Winder, D.G.7
Adams, J.P.8
Sweatt, J.D.9
Kandel, E.R.10
-
54
-
-
0033580841
-
Circadian regulation of cAMP response element-mediated gene expression in the suparachiasmatic nuclei
-
Obrietan K., Impey S., Smith D., Athos J., and Storm D.R. Circadian regulation of cAMP response element-mediated gene expression in the suparachiasmatic nuclei. J. Biol. Chem. 274 (1999) 17748-17756
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17748-17756
-
-
Obrietan, K.1
Impey, S.2
Smith, D.3
Athos, J.4
Storm, D.R.5
-
55
-
-
0033637570
-
Morphine-6β-glucronide has a higher efficacy than morphine as mu-opioid receptor agonist in the rat locus coeruleus
-
Osborne P.B., Chieng B., and Christie M.J. Morphine-6β-glucronide has a higher efficacy than morphine as mu-opioid receptor agonist in the rat locus coeruleus. Br. J. Pharmacol. 131 (2000) 1422-1428
-
(2000)
Br. J. Pharmacol.
, vol.131
, pp. 1422-1428
-
-
Osborne, P.B.1
Chieng, B.2
Christie, M.J.3
-
56
-
-
0025209851
-
Myoclonic seizure activity with chronic high-dose spinal opioid administration
-
Parkinson S.K., Bailey S.L., Little W.L., and Mueller J.B. Myoclonic seizure activity with chronic high-dose spinal opioid administration. Anesthesiology 72 (1990) 743-745
-
(1990)
Anesthesiology
, vol.72
, pp. 743-745
-
-
Parkinson, S.K.1
Bailey, S.L.2
Little, W.L.3
Mueller, J.B.4
-
57
-
-
0023620266
-
Morphine-6-glucuronide, a potent mu agonist
-
Pasternak G.W., Bodnar R.J., Clark J.A., and Intrurrisi C.E. Morphine-6-glucuronide, a potent mu agonist. Life Sci. 41 (1987) 2845-2849
-
(1987)
Life Sci.
, vol.41
, pp. 2845-2849
-
-
Pasternak, G.W.1
Bodnar, R.J.2
Clark, J.A.3
Intrurrisi, C.E.4
-
58
-
-
0024369341
-
Pharmacological characterization of morphine-6-glucuronide, a very potent morphine metabolite
-
Paul D., Standifer K.M., Intrurrisi C.E., and Pasternak G.W. Pharmacological characterization of morphine-6-glucuronide, a very potent morphine metabolite. J. Pharmacol. Exp. Ther. 251 (1989) 477-483
-
(1989)
J. Pharmacol. Exp. Ther.
, vol.251
, pp. 477-483
-
-
Paul, D.1
Standifer, K.M.2
Intrurrisi, C.E.3
Pasternak, G.W.4
-
59
-
-
0023278495
-
Chronic intrathecal morphine for intractable pain
-
Penn R., and Paice J. Chronic intrathecal morphine for intractable pain. J. Neurosurg. 67 (1987) 182-186
-
(1987)
J. Neurosurg.
, vol.67
, pp. 182-186
-
-
Penn, R.1
Paice, J.2
-
60
-
-
0024970939
-
Myoclonus associated with treatment with high doses of morphine: The role of supplemental drugs
-
Potter J.M., Reid D.B., Shaw R.J., Hackett P., and Hickmann P.E. Myoclonus associated with treatment with high doses of morphine: The role of supplemental drugs. Br. Med. J. 299 (1989) 150-153
-
(1989)
Br. Med. J.
, vol.299
, pp. 150-153
-
-
Potter, J.M.1
Reid, D.B.2
Shaw, R.J.3
Hackett, P.4
Hickmann, P.E.5
-
61
-
-
0030002043
-
cGMP-dependent protein kinase in dorsal root ganglion: Relationship with nitric oxide synthase and nociceptive neurons
-
Qian Y., Chao D.S., Santillano D.R., Cornwell T.L., Narin A.C., Greengard P., Lincoln T.M., and Bredt D.S. cGMP-dependent protein kinase in dorsal root ganglion: Relationship with nitric oxide synthase and nociceptive neurons. J. Neurosci. 16 (1996) 3130-3138
-
(1996)
J. Neurosci.
, vol.16
, pp. 3130-3138
-
-
Qian, Y.1
Chao, D.S.2
Santillano, D.R.3
Cornwell, T.L.4
Narin, A.C.5
Greengard, P.6
Lincoln, T.M.7
Bredt, D.S.8
-
62
-
-
0037112041
-
The role of spinal neuroimmune activation in morphine tolerance/hyperalgesia in neuropathic and sham-operated rats
-
Raghavendra V., Tanga F.Y., and DeLeo J.A. The role of spinal neuroimmune activation in morphine tolerance/hyperalgesia in neuropathic and sham-operated rats. J. Neurosci. 22 (2002) 9980-9989
-
(2002)
J. Neurosci.
, vol.22
, pp. 9980-9989
-
-
Raghavendra, V.1
Tanga, F.Y.2
DeLeo, J.A.3
-
63
-
-
0037622717
-
Inhibition of micloglia activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy
-
Raghavendra V., Tanga F.Y., and DeLeo J.A. Inhibition of micloglia activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy. J. Pharmacol. Exp. Ther. 306 (2003) 624-630
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.306
, pp. 624-630
-
-
Raghavendra, V.1
Tanga, F.Y.2
DeLeo, J.A.3
-
64
-
-
3242758909
-
Complete Freunds adjuvant-induced peripheral inflammation evokes glial activation and proinflammatory cytokine expression in the CNS
-
Raghavendra V., Tanga F.Y., and DeLeo J.A. Complete Freunds adjuvant-induced peripheral inflammation evokes glial activation and proinflammatory cytokine expression in the CNS. Eur. J. Neurosci. 20 (2004) 467-473
-
(2004)
Eur. J. Neurosci.
, vol.20
, pp. 467-473
-
-
Raghavendra, V.1
Tanga, F.Y.2
DeLeo, J.A.3
-
65
-
-
0030591471
-
Spinally-mediated behavioral responses evoked by intrathecal high-dose morphine: Possible involvement of substance P in the mouse spinal cord
-
Sakurada T., Wako K., Sakurada C., Manome Y., Tan-No K., Sakurada S., and Kisara K. Spinally-mediated behavioral responses evoked by intrathecal high-dose morphine: Possible involvement of substance P in the mouse spinal cord. Brain Res. 724 (1996) 213-221
-
(1996)
Brain Res.
, vol.724
, pp. 213-221
-
-
Sakurada, T.1
Wako, K.2
Sakurada, C.3
Manome, Y.4
Tan-No, K.5
Sakurada, S.6
Kisara, K.7
-
66
-
-
0030245813
-
Involvement of nitric oxide in spinally mediated capsaicin- and glutamate-induced behavioural responses in the mouse
-
Sakurada T., Sugiyama A., Sakurada C., Tan-No K., Sakurada S., Kisara K., Hara A., and Abiko Y. Involvement of nitric oxide in spinally mediated capsaicin- and glutamate-induced behavioural responses in the mouse. Neurchem. Int. 29 (1996) 271-278
-
(1996)
Neurchem. Int.
, vol.29
, pp. 271-278
-
-
Sakurada, T.1
Sugiyama, A.2
Sakurada, C.3
Tan-No, K.4
Sakurada, S.5
Kisara, K.6
Hara, A.7
Abiko, Y.8
-
67
-
-
0035105760
-
Antinociceptive effect of spinally injected L-NAME on the acute nociceptive response induced by low concentrations of formalin
-
Sakurada C., Sugiyama A., Nakayama M., Yonezawa A., Sakurada S., Tan-No K., Kisara K., and Sakurada S. Antinociceptive effect of spinally injected L-NAME on the acute nociceptive response induced by low concentrations of formalin. Neurochem. Int. 38 (2001) 417-423
-
(2001)
Neurochem. Int.
, vol.38
, pp. 417-423
-
-
Sakurada, C.1
Sugiyama, A.2
Nakayama, M.3
Yonezawa, A.4
Sakurada, S.5
Tan-No, K.6
Kisara, K.7
Sakurada, S.8
-
68
-
-
0037203852
-
Intrathecal high-dose morphine induces spinally-mediated behavioral responses through NMDA receptors
-
Sakurada T., Watanabe C., Okuda K., Sugiyama A., Moriyama T., Sakurada C., Tan-No K., and Sakurada S. Intrathecal high-dose morphine induces spinally-mediated behavioral responses through NMDA receptors. Mol. Brain Res. 98 (2002) 111-118
-
(2002)
Mol. Brain Res.
, vol.98
, pp. 111-118
-
-
Sakurada, T.1
Watanabe, C.2
Okuda, K.3
Sugiyama, A.4
Moriyama, T.5
Sakurada, C.6
Tan-No, K.7
Sakurada, S.8
-
69
-
-
0035932121
-
Interleukin-1 beta-mediated induction of cox-2 in the CNS contributes to inflammatory pain hypersensitivity
-
Samad T.A., Moore K.A., Sapirstein A., Billet S., Allchorne A., Poole S., Bonventre J.V., and Woolf C.J. Interleukin-1 beta-mediated induction of cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature 410 (2001) 471-475
-
(2001)
Nature
, vol.410
, pp. 471-475
-
-
Samad, T.A.1
Moore, K.A.2
Sapirstein, A.3
Billet, S.4
Allchorne, A.5
Poole, S.6
Bonventre, J.V.7
Woolf, C.J.8
-
70
-
-
0037333607
-
Inhibition of cyclic guanosine 5′-monophosphate-dependent protein kinase I (PKG-I) in lumbar spinal cord reduces formalin-induced hyperalgesia and PKG upregulation
-
Schmidtko A., Ruth P., Geisslinger G., and Tegeder I. Inhibition of cyclic guanosine 5′-monophosphate-dependent protein kinase I (PKG-I) in lumbar spinal cord reduces formalin-induced hyperalgesia and PKG upregulation. Nitric Oxide 8 (2003) 89-94
-
(2003)
Nitric Oxide
, vol.8
, pp. 89-94
-
-
Schmidtko, A.1
Ruth, P.2
Geisslinger, G.3
Tegeder, I.4
-
71
-
-
35548937457
-
The neuropathic pain triad: Neurons, immune cells and glia
-
Scholz J., and Woolf C.J. The neuropathic pain triad: Neurons, immune cells and glia. Nat. Neurosci. 10 (2007) 1361-1368
-
(2007)
Nat. Neurosci.
, vol.10
, pp. 1361-1368
-
-
Scholz, J.1
Woolf, C.J.2
-
72
-
-
0030606802
-
Alterations in rat spinal cord cGMP by peripheral nerve injury and adrenal medullary transplantation
-
Siegan J.B., Hama A.T., and Sagen J. Alterations in rat spinal cord cGMP by peripheral nerve injury and adrenal medullary transplantation. Neurosci. Lett. 215 (1996) 49-52
-
(1996)
Neurosci. Lett.
, vol.215
, pp. 49-52
-
-
Siegan, J.B.1
Hama, A.T.2
Sagen, J.3
-
73
-
-
0027527448
-
Hyperalgesia and myoclonus in terminal cancer patients treated with continuous intravenous morphine
-
Sjogren P., Jonsson T., Jensen N.H., Drenck N.E., and Jensen T.S. Hyperalgesia and myoclonus in terminal cancer patients treated with continuous intravenous morphine. Pain 55 (1993) 93-97
-
(1993)
Pain
, vol.55
, pp. 93-97
-
-
Sjogren, P.1
Jonsson, T.2
Jensen, N.H.3
Drenck, N.E.4
Jensen, T.S.5
-
74
-
-
0026605218
-
Selective potentiation of NMDA-induced activity and release of excitatory amino acids by dynorphine: Possible roles in paralysis and neurotoxicity
-
Skilling S.R., Sun X., Kurtz H.J., and Larson A.A. Selective potentiation of NMDA-induced activity and release of excitatory amino acids by dynorphine: Possible roles in paralysis and neurotoxicity. Brain Res. 575 (1992) 272-278
-
(1992)
Brain Res.
, vol.575
, pp. 272-278
-
-
Skilling, S.R.1
Sun, X.2
Kurtz, H.J.3
Larson, A.A.4
-
75
-
-
0034053670
-
Neuroexcitatory effects of morphine and hydromorphine: Evidence implicating the 3-glucuronide metabolites
-
Smith M.T. Neuroexcitatory effects of morphine and hydromorphine: Evidence implicating the 3-glucuronide metabolites. Clin. Exp. Pharmacol. Physiol. 27 (2000) 524-528
-
(2000)
Clin. Exp. Pharmacol. Physiol.
, vol.27
, pp. 524-528
-
-
Smith, M.T.1
-
76
-
-
3042561735
-
Intrathecal interleukin-1beta administration induces themal hyperalgesia by activating inducible nitric oxide synthase expression in the rat spinal cord
-
Sung C.S., Wen Z.H., Chang W.K., Ho S.T., Tsai S.K., Chang Y.C., and Wong C.S. Intrathecal interleukin-1beta administration induces themal hyperalgesia by activating inducible nitric oxide synthase expression in the rat spinal cord. Brain Res. 1051 (2004) 145-153
-
(2004)
Brain Res.
, vol.1051
, pp. 145-153
-
-
Sung, C.S.1
Wen, Z.H.2
Chang, W.K.3
Ho, S.T.4
Tsai, S.K.5
Chang, Y.C.6
Wong, C.S.7
-
77
-
-
0035857748
-
Intrathecal interleukin-1 receptor antagonist in combunation with soluble tumor necrosis factor receptor exhibits an anti-allodynic action in a rat model of neuropathic pain
-
Sweitzer S., Martin D., and DeLeo J.A. Intrathecal interleukin-1 receptor antagonist in combunation with soluble tumor necrosis factor receptor exhibits an anti-allodynic action in a rat model of neuropathic pain. Neuroscience 103 (2001) 529-539
-
(2001)
Neuroscience
, vol.103
, pp. 529-539
-
-
Sweitzer, S.1
Martin, D.2
DeLeo, J.A.3
-
78
-
-
33746809553
-
Amitriptyline suppresses neuroinflammation and up regulates glutamate transporters in morphine-tolerant rats
-
Tai Y.H., Wang Y.H., Wang J.J., Tao P.L., Tung C.S., and Wong C.S. Amitriptyline suppresses neuroinflammation and up regulates glutamate transporters in morphine-tolerant rats. Pain 124 (2006) 77-86
-
(2006)
Pain
, vol.124
, pp. 77-86
-
-
Tai, Y.H.1
Wang, Y.H.2
Wang, J.J.3
Tao, P.L.4
Tung, C.S.5
Wong, C.S.6
-
79
-
-
0018227414
-
Comparison of subcutaneous and spinal subarachnoid injections of morphine and naloxone in analgesic tests in rat
-
Tang A.H., and Schoenfeld H.J. Comparison of subcutaneous and spinal subarachnoid injections of morphine and naloxone in analgesic tests in rat. Eur. J. Pharmacol. 52 (1978) 215-223
-
(1978)
Eur. J. Pharmacol.
, vol.52
, pp. 215-223
-
-
Tang, A.H.1
Schoenfeld, H.J.2
-
80
-
-
0032714373
-
Expression and action of cyclic GMP-dependent protein kinase Ialpha in inflammatory hyperalgesia in rat spinal cord
-
Tao Y.X., Hassan A., Haddad E., and Johns R.A. Expression and action of cyclic GMP-dependent protein kinase Ialpha in inflammatory hyperalgesia in rat spinal cord. Neuroscience 95 (2000) 525-533
-
(2000)
Neuroscience
, vol.95
, pp. 525-533
-
-
Tao, Y.X.1
Hassan, A.2
Haddad, E.3
Johns, R.A.4
-
81
-
-
0037206670
-
Dual effects of spinally delivered 8-bromo-cyclic guanosine mono-phosphate (8-bromo-cGMP) in formalin-induced nociception in rats
-
Tegeder I., Schmidtko A., Niederberger E., Ruth P., and Geisslinger G. Dual effects of spinally delivered 8-bromo-cyclic guanosine mono-phosphate (8-bromo-cGMP) in formalin-induced nociception in rats. Neurosci. Lett. 332 (2002) 146-150
-
(2002)
Neurosci. Lett.
, vol.332
, pp. 146-150
-
-
Tegeder, I.1
Schmidtko, A.2
Niederberger, E.3
Ruth, P.4
Geisslinger, G.5
-
82
-
-
1542357662
-
Reduced inflammatory hyperalgesia with preservation of acute thermal nociception in mice lacking cGMP-dependent protein kinase I
-
Tegeder I., Del Turco D., Schmidtko A., Sausbier M., Feil R., Hofmann F., Deller T., Ruth P., and Geisslinger G. Reduced inflammatory hyperalgesia with preservation of acute thermal nociception in mice lacking cGMP-dependent protein kinase I. Proc. Natl. Acad. Sci. USA 101 (2004) 3253-3257
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3253-3257
-
-
Tegeder, I.1
Del Turco, D.2
Schmidtko, A.3
Sausbier, M.4
Feil, R.5
Hofmann, F.6
Deller, T.7
Ruth, P.8
Geisslinger, G.9
-
83
-
-
13144276331
-
Neuropathic pain and spinal microglia: A big problem from molecules in "small" glia
-
Tsuda M., Inoue K., and Salter M.W. Neuropathic pain and spinal microglia: A big problem from molecules in "small" glia. Trends Neurosci. 28 (2005) 101-107
-
(2005)
Trends Neurosci.
, vol.28
, pp. 101-107
-
-
Tsuda, M.1
Inoue, K.2
Salter, M.W.3
-
84
-
-
17344385566
-
Single intrathecal injections of dynorphin A or des-Tyr-dynorphins produce long-lasting allodynia on rats: Blockade by MK-801 but not naloxone
-
Vanderah T.W., Laughlin T.M., Lashbrook J.M., Nichols M.L., Wilcox G.L., Ossipov M.H., Malan T.P., and Porreca F. Single intrathecal injections of dynorphin A or des-Tyr-dynorphins produce long-lasting allodynia on rats: Blockade by MK-801 but not naloxone. Pain 68 (1996) 275-281
-
(1996)
Pain
, vol.68
, pp. 275-281
-
-
Vanderah, T.W.1
Laughlin, T.M.2
Lashbrook, J.M.3
Nichols, M.L.4
Wilcox, G.L.5
Ossipov, M.H.6
Malan, T.P.7
Porreca, F.8
-
85
-
-
0034666274
-
Dynorphine promotes abnormal pain and spinal opioid antinociceptive tolerance
-
Vanderah T.W., Gardell L.R., Birgess S.E., Ibrahim M., Dogrul A., Zhong C.M., Zhang E.T., Malan Jr. T.P., Ossipov M.H., Lai J., and Porreca F. Dynorphine promotes abnormal pain and spinal opioid antinociceptive tolerance. J. Neurosci. 20 (2000) 7074-7079
-
(2000)
J. Neurosci.
, vol.20
, pp. 7074-7079
-
-
Vanderah, T.W.1
Gardell, L.R.2
Birgess, S.E.3
Ibrahim, M.4
Dogrul, A.5
Zhong, C.M.6
Zhang, E.T.7
Malan Jr. T.P.8
Ossipov, M.H.9
Lai, J.10
Porreca, F.11
-
86
-
-
0029670427
-
Pre-emptive dynorphine and N-methyl-d-asparatate glutamate receptor antagonism alters spinal immunocytochemistry but not allodynia following complete peripheral nerve injury
-
Wagner R., and Deleo J.A. Pre-emptive dynorphine and N-methyl-d-asparatate glutamate receptor antagonism alters spinal immunocytochemistry but not allodynia following complete peripheral nerve injury. Neurocsience 72 (1996) 527-534
-
(1996)
Neurocsience
, vol.72
, pp. 527-534
-
-
Wagner, R.1
Deleo, J.A.2
-
87
-
-
0035282798
-
Pronociceptive actions of dynorphin maintain chronic neuropathic pain
-
Wang Z., Gardell L.R., Ossipov M.H., Vanderah T.W., Brennan M.B., Hochgeschwender U., Hruby V.J., Malan T.P., Lai J., and Porreca F. Pronociceptive actions of dynorphin maintain chronic neuropathic pain. J. Neurosci. 21 (2001) 1779-1786
-
(2001)
J. Neurosci.
, vol.21
, pp. 1779-1786
-
-
Wang, Z.1
Gardell, L.R.2
Ossipov, M.H.3
Vanderah, T.W.4
Brennan, M.B.5
Hochgeschwender, U.6
Hruby, V.J.7
Malan, T.P.8
Lai, J.9
Porreca, F.10
-
88
-
-
0344305586
-
The role of spinal nitric oxide and glutamate in nociceptive behaviour evoked by high-dose intrathecal morphine in rats
-
Watanabe C., Sakurada T., Okuda K., Sakurada C., Ando R., and Sakurada S. The role of spinal nitric oxide and glutamate in nociceptive behaviour evoked by high-dose intrathecal morphine in rats. Pain 106 (2003) 269-283
-
(2003)
Pain
, vol.106
, pp. 269-283
-
-
Watanabe, C.1
Sakurada, T.2
Okuda, K.3
Sakurada, C.4
Ando, R.5
Sakurada, S.6
-
89
-
-
0141918795
-
Evidence that nitric oxide-glutamate cascade modulates spinal antinociceptive effect of morphine: A behavioural and microdialysis study in rats
-
Watanabe C., Okuda K., Sakurada C., Ando R., Sakurada T., and Sakurada S. Evidence that nitric oxide-glutamate cascade modulates spinal antinociceptive effect of morphine: A behavioural and microdialysis study in rats. Brain Res. 990 (2003) 77-86
-
(2003)
Brain Res.
, vol.990
, pp. 77-86
-
-
Watanabe, C.1
Okuda, K.2
Sakurada, C.3
Ando, R.4
Sakurada, T.5
Sakurada, S.6
-
90
-
-
0347169249
-
Glia: Novel drug discovery target for clinical pain
-
Watkins L.R., and Maier S.F. Glia: Novel drug discovery target for clinical pain. Nat. Rev. Drug Discov. 2 (2003) 973-985
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, pp. 973-985
-
-
Watkins, L.R.1
Maier, S.F.2
-
91
-
-
0035426434
-
Glial activation: A driving force for pathological pain
-
Watkins L.R., Milligan E.D., and Maier S.F. Glial activation: A driving force for pathological pain. Trends Neurosci. 24 (2001) 450-455
-
(2001)
Trends Neurosci.
, vol.24
, pp. 450-455
-
-
Watkins, L.R.1
Milligan, E.D.2
Maier, S.F.3
-
92
-
-
0038748399
-
Glial proinflammatory cytokines mediate exaggerated pain states: Implications for clinical pain
-
Watkins L.R., Milligan E.D., and Maier S.F. Glial proinflammatory cytokines mediate exaggerated pain states: Implications for clinical pain. Adv. Exp. Med. Biol. 521 (2003) 1-21
-
(2003)
Adv. Exp. Med. Biol.
, vol.521
, pp. 1-21
-
-
Watkins, L.R.1
Milligan, E.D.2
Maier, S.F.3
-
93
-
-
0020078102
-
Opiate alkaloids antagonize postsynaptic glycine and GABA responses: Correlation with convulsant action
-
Wert M.A., and MacDonald R.L. Opiate alkaloids antagonize postsynaptic glycine and GABA responses: Correlation with convulsant action. Brain Res. 236 (1982) 107-119
-
(1982)
Brain Res.
, vol.236
, pp. 107-119
-
-
Wert, M.A.1
MacDonald, R.L.2
-
94
-
-
0035888084
-
Nerve injury proximal or distal to the DRG induces similar spinal glial activation and selective cytokine expression but differential behavioral responses to pharmacologic treatment
-
Winkelstein B.A., Rutkowski M.D., Sweitzer S.M., Pahl J.L., and Deleo J.A. Nerve injury proximal or distal to the DRG induces similar spinal glial activation and selective cytokine expression but differential behavioral responses to pharmacologic treatment. J. Comp Neurol. 439 (2001) 127-139
-
(2001)
J. Comp Neurol.
, vol.439
, pp. 127-139
-
-
Winkelstein, B.A.1
Rutkowski, M.D.2
Sweitzer, S.M.3
Pahl, J.L.4
Deleo, J.A.5
-
95
-
-
0019524261
-
Intrathecal high dose morphine produces hyperalgesia in the rat
-
Woolf F.J. Intrathecal high dose morphine produces hyperalgesia in the rat. Brain Res. 209 (1981) 491-495
-
(1981)
Brain Res.
, vol.209
, pp. 491-495
-
-
Woolf, F.J.1
-
96
-
-
0032498806
-
Nitric oxide contributes to central sensitization following intradermal injection of capsaicin
-
Wu J., Lin Q., McAdoo D.J., and Willis W.D. Nitric oxide contributes to central sensitization following intradermal injection of capsaicin. NeuroReport 9 (1998) 589-592
-
(1998)
NeuroReport
, vol.9
, pp. 589-592
-
-
Wu, J.1
Lin, Q.2
McAdoo, D.J.3
Willis, W.D.4
-
97
-
-
0023829817
-
Parmacology of the allodynia in rats evoked by high dose intrathecal morphine
-
Yaksh T.L., and Harty G.J. Parmacology of the allodynia in rats evoked by high dose intrathecal morphine. J. Pharmacol. Exp. Ther. 244 (1988) 501-507
-
(1988)
J. Pharmacol. Exp. Ther.
, vol.244
, pp. 501-507
-
-
Yaksh, T.L.1
Harty, G.J.2
-
98
-
-
0022558928
-
High doses of spinal morphine produce a nonopiate receptor-mediated hyperesthesia: Clinical and theoretical implications
-
Yaksh T.L., Harty G.J., Burton M., and Onofrio B.M. High doses of spinal morphine produce a nonopiate receptor-mediated hyperesthesia: Clinical and theoretical implications. Anesthesiology 64 (1986) 590-597
-
(1986)
Anesthesiology
, vol.64
, pp. 590-597
-
-
Yaksh, T.L.1
Harty, G.J.2
Burton, M.3
Onofrio, B.M.4
-
99
-
-
1642513343
-
Formation of highly analgesic morphine-6-gluclonide following physiologic concentration of morphine in human brain
-
Yamada H., Ishii K., Ishii Y., Ieiri I., Nishio S., Morioka T., and Oguri K. Formation of highly analgesic morphine-6-gluclonide following physiologic concentration of morphine in human brain. J. Toxicol. Sci. 28 (2003) 395-401
-
(2003)
J. Toxicol. Sci.
, vol.28
, pp. 395-401
-
-
Yamada, H.1
Ishii, K.2
Ishii, Y.3
Ieiri, I.4
Nishio, S.5
Morioka, T.6
Oguri, K.7
-
100
-
-
0037435884
-
Involvement of NMDA-nitric oxide pathways in the development of tactile hypersensitivity evoked by the loose-ligation of inferior alveolar nerves in rats
-
Yonehara N., Kudo C., and Kamisaki Y. Involvement of NMDA-nitric oxide pathways in the development of tactile hypersensitivity evoked by the loose-ligation of inferior alveolar nerves in rats. Brain Res. 963 (2003) 232-243
-
(2003)
Brain Res.
, vol.963
, pp. 232-243
-
-
Yonehara, N.1
Kudo, C.2
Kamisaki, Y.3
-
101
-
-
40049094003
-
IL-1ra alleviates inflammatory hyperalgesia through preventing phosphorylation of NMDA receptor NR-1 subunit in rats
-
Zhang R.X., Li S., Liu B., Wang L., Ren K., Zhang H., Berman B.M., and Lao L. IL-1ra alleviates inflammatory hyperalgesia through preventing phosphorylation of NMDA receptor NR-1 subunit in rats. Pain 135 (2008) 232-239
-
(2008)
Pain
, vol.135
, pp. 232-239
-
-
Zhang, R.X.1
Li, S.2
Liu, B.3
Wang, L.4
Ren, K.5
Zhang, H.6
Berman, B.M.7
Lao, L.8
-
102
-
-
0037162696
-
Ras and Rap control AMPA receptor trafficking during synaptic plasticity
-
Zhu J.J., Qin Y., Zhao M., Van Aelst L., and Malinow R. Ras and Rap control AMPA receptor trafficking during synaptic plasticity. Cell 110 (2002) 443-455
-
(2002)
Cell
, vol.110
, pp. 443-455
-
-
Zhu, J.J.1
Qin, Y.2
Zhao, M.3
Van Aelst, L.4
Malinow, R.5
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