-
1
-
-
85114544270
-
-
Aanonsen, L.M. and Wilcox, G.L., Nociceptive action of excitatory amino acids in the mouse: effects of spinally administered opioids, phencyclidine and σ agonists, J. Pharmacol. Exp. Ther., 243 (1987) 9–19.
-
-
-
-
2
-
-
85114545401
-
-
Bakshi, R. and Faden, A.I., Competitive and non-competitive NMDA antagonists limit dynorphin A-induced rat hindlimb paralysis, Brain Res., 507 (1990) 1–5.
-
-
-
-
3
-
-
85114551602
-
-
Bakshi, R., Ni, R.X. and Faden, A.I., N -methyl- d -aspartate (NMDA) and opioid receptors mediate dynorphin-induced spinal cord injury: behavioral and histological studies, Brain Res., 580 (1992) 255–264.
-
-
-
-
4
-
-
85114525345
-
-
Brauneis, U., Peoples, R.W., Oz, M., Weight, F.F. and Zhang, L., Potentiation of NMDA receptor-mediated responses by dynorphin at low glycine, Soc. Neurosci. Abstr., 22 (1996) 67.
-
-
-
-
5
-
-
85114543614
-
-
Carlton, S.M. and Hargett, G.L., Treatment with the NMDA antagonist memantine attenuates nociceptive responses to mechanical stimulation in neuropathic rats, Neurosci. Lett., 198 (1995) 115–118.
-
-
-
-
6
-
-
85114551630
-
-
Caudle, R.M. and Isaac, L., Intrathecal dynorphin (1-13) results in an irreversible loss of the tail-flick reflex in rats, Brain Res., 435 (1987) 1–6.
-
-
-
-
7
-
-
85114551571
-
-
Caudle, R.M. and Isaac, L., Influence of dynorphin (1-13) on spinal reflexes in the rat, J. Pharmacol. Exp. Ther., 246 (1988a) 508–513.
-
-
-
-
8
-
-
85114534017
-
-
Caudle, R.M. and Isaac, L., A novel interaction between dynorphin (1-13) and an N -methyl- d -aspartate site, Brain Res., 443 (1988b) 329–332.
-
-
-
-
9
-
-
85114534429
-
-
Chen, L., Gu, Y. and Huang, L.Y., The mechanism of action for the block of NMDA receptor channels by the opioid peptide dynorphin, J. Neurosci., 15 (1995) 4602–4611.
-
-
-
-
10
-
-
85114527837
-
-
Choi, Y., Yoon, Y.W., Na, H.S., Kim, S.H. and Chung, J.M., Behavioral signs of ongoing pain and cold allodynia in a rat model of neuropathic pain, Pain, 59 (1994) 369–376.
-
-
-
-
11
-
-
85114552398
-
-
Cox, B.M., Molineaux, C.J., Jacobs, T.P., Rosenberger, J.G. and Faden, A.I., Effects of traumatic injury on dynorphin immunoreactivity in spinal cord, Neuropeptides, 5 (1985) 571–574.
-
-
-
-
12
-
-
85114547752
-
-
Davies, S.N. and Lodge, D., Evidence for involvement of N -methylaspartate receptors in `wind-up' of class 2 neurons in the dorsal horn of the rat, Brain Res., 424 (1987) 402–406.
-
-
-
-
13
-
-
85114528433
-
-
Dickenson, A.H. and Sullivan, A.F., Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurons following C fiber stimulation, Neuropharmacology, 26 (1987) 1235–1238.
-
-
-
-
14
-
-
85114541720
-
-
Dubner, R. and Ruda, M.A., Activity-dependent neuronal plasticity following tissue injury and inflammation, Trends Neurosci., 15 (1992) 96–103.
-
-
-
-
15
-
-
85114524648
-
-
Faden, A.I., Opioid and non-opioid mechanisms may contribute to dynorphin's pathophysiological actions in spinal cord injury, Ann. Neurol., 27 (1990) 67–74.
-
-
-
-
16
-
-
85114547131
-
-
Faden, A.I., Dynorphin increases extracellular levels of excitatory amino acids in the brain through a non-opioid mechanism, J. Neurosci., 12 (1992) 425–429.
-
-
-
-
17
-
-
85114524419
-
-
Faden, A.I. and Jacobs, T.P., Dynorphin-related peptides cause motor dysfunction in the rat through a non-opiate action, Br. J. Pharmacol., 81 (1984) 271–276.
-
-
-
-
18
-
-
85114549277
-
-
Faden, A.I., Molineaux, C.J., Rosenberger, J.G., Jacobs, T.P. and Cox, B.M., Endogenous opioid immunoreactivity in rat spinal cord following traumatic injury, Ann. Neurol., 17 (1985) 386–390.
-
-
-
-
19
-
-
85114527806
-
-
Haley, J.E. and Wilcox, G.L., Involvement of excitatory amino acids and peptides in the spinal mechanisms underlying hyperalgesia. In: W.D. Willis (Ed.), Hyperalgesia and Allodynia, Raven Press, New York, 1992, pp. 281–293.
-
-
-
-
20
-
-
85114528810
-
-
Hao, J.X., Xu, X.J., Aldskogius, H., Seiger, A. and Wiesenfeld-Hallin, Z., Allodynia-like effects in rat after ischaemic spinal cord injury photochemically induced by laser irradiation, Pain, 45 (1991) 175–185.
-
-
-
-
21
-
-
85114527604
-
-
Hu, W.H., Lee, F.C., Wan, X., Chen, Y.T. and Jen, M.F., Dynorphin neurotoxicity induced nitric oxide synthase expression in ventral horn cells of rat spinal cord, Neurosci. Lett., 203 (1996) 13–16.
-
-
-
-
22
-
-
85114529585
-
-
Hylden, J.L.K. and Wilcox, G.L., Intrathecal morphine in mice: a new technique, Eur. J. Pharmacol., 67 (1980) 313–316.
-
-
-
-
23
-
-
85114528592
-
-
Hylden, J.L., Nahin, R.L., Traub, R.J. and Dubner, R., Effects of spinal kappa-opioid receptor agonists on the responsiveness of nociceptive superficial dorsal horn neurons, Pain, 44 (1991) 187–193.
-
-
-
-
24
-
-
85114551531
-
-
Iadarola, M.J., Brady, L.S., Draisci, G. and Dubner, R., Enhancement of dynorphin gene expression in spinal cord following experimental inflammation: stimulus specificity, behavioral parameters and opioid receptor binding, Pain, 35 (1988) 313–326.
-
-
-
-
25
-
-
85114543164
-
-
Kajander, K.C., Sahara, Y., Iadarola, M.J. and Bennett, G.J., Dynorphin increases in the dorsal spinal cord in rats with a painful peripheral neuropathy, Peptides, 11 (1990) 719–728.
-
-
-
-
26
-
-
85114551577
-
-
Knox, R.J. and Dickenson, A.H., Effects of selective and non-selective kappa-opioid receptor agonists on cutaneous C-fibre-evoked responses of rat dorsal horn neurones, Brain Res., 415 (1987) 21–29.
-
-
-
-
27
-
-
85114528925
-
-
Long, J.B. and Skolnick, P., 1-Aminocyclopropanecarboxylic acid protects against dynorphin A-induced spinal injury, Eur. J. Pharmacol., 261 (1994) 295–301.
-
-
-
-
28
-
-
85114527132
-
-
3-13 reduce rat spinal cord blood flow by non-opioid mechanisms, Brain Res., 436 (1987) 374–379.
-
-
-
-
29
-
-
85114524425
-
-
Long, J.B., Petras, J.M., Mobley, W.C. and Holaday, J.W., Neurological dysfunction after intrathecal injection of dynorphin A (1-13) in the rat. II. Non-opioid mechanisms mediate loss of motor, sensory and autonomic function, J. Pharmacol. Exp. Ther., 246 (1988) 1167–1174.
-
-
-
-
30
-
-
85114524778
-
-
Long, J.B., Rigamonti, D.D., Oleshansky, M.A., Wingfield, C.P. and Martinez-Arizala, A., Dynorphin A-induced rat spinal cord injury: evidence for excitatory amino acid involvement in a pharmacological model of ischemic spinal cord injury, J. Pharmacol. Exp. Ther., 269 (1994) 358–366.
-
-
-
-
31
-
-
85114526731
-
-
Ma, Q.P. and Woolf, C.J., Noxious stimuli induce an N -methyl- d -aspartate receptor-dependent hypersensitivity of the flexion withdrawal reflex to touch: implications for the treatment of mechanical allodynia, Pain, 61 (1995) 383–390.
-
-
-
-
32
-
-
85114533501
-
-
Magnuson, D.S. and Dickenson, A.H., Lamina-specific effects of morphine and naloxone in dorsal horn of rat spinal cord in vitro, J. Neurophysiol., 66 (1991) 1941–1950.
-
-
-
-
33
-
-
85114543977
-
-
Mao, J., Price, D.D., Hayes, R.L., Lu, J. and Mayer, D.J., Differential roles of NMDA and non-NMDA receptor activation in induction and maintenance of thermal hyperalgesia in rats with painful peripheral mononeuropathy, Brain Res., 598 (1992) 271–278.
-
-
-
-
34
-
-
85114542896
-
-
Massardier, D. and Hunt, P.F., A direct non-opiate interaction of dynorphin-(1-13) with the N -methyl- d -aspartate (NMDA) receptor, Eur. J. Pharmacol., 170 (1989) 125–126.
-
-
-
-
35
-
-
85114535468
-
-
Miller, K.E. and Seybold, V.S., Comparison of met-enkephalin, dynorphin A, and neurotensin immunoreactive neurons in the cat and rat spinal cords: II. Segmental differences in the marginal zone, J. Comp. Neurol., 279 (1989) 619–628.
-
-
-
-
36
-
-
85114550952
-
-
Randic, M., Cheng, G. and Kojic, L., k-Opioid receptor agonists modulate excitatory transmission in substantia gelatinosa neurons of the rat spinal cord, J. Neurosci., 15 (1995) 6809–6826.
-
-
-
-
37
-
-
85114532944
-
-
Ren, K. and Dubner, R., NMDA receptor antagonists attenuate mechanical hyperalgesia in rats with unilateral inflammation of the hindpaw, Neurosci. Lett., 163 (1993) 22–26.
-
-
-
-
38
-
-
85114550827
-
-
Ren, K., Hylden, J.L., Williams, G.M., Ruda, M.A. and Dubner, R., The effects of a non-competitive NMDA receptor antagonist, MK-801, on behavioral hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammation, Pain, 50 (1992) 331–344.
-
-
-
-
39
-
-
85114551107
-
-
Ruda, M.A., Iadarola, M.J., Cohen, L.V. and Young, W., In situ hybridization, histochemistry and immunocytochemistry reveal an increase in spinal dynorphin biosynthesis in a rat model of peripheral inflammation and hyperalgesia, Proc. Natl. Acad. Sci. USA, 85 (1988) 622–626.
-
-
-
-
40
-
-
85114550898
-
-
Seltzer, Z., Cohn, S., Ginzburg, R. and Beilin, B., Modulation of neuropathic pain behavior in rats by spinal disinhibition and NMDA receptor blockade of injury discharge, Pain, 45 (1991) 69–75.
-
-
-
-
41
-
-
85114538338
-
-
Sherman, S.E. and Loomis, C.W., Morphine insensitive allodynia is produced by intrathecal strychnine in the lightly anesthetized rat, Pain, 56 (1994) 17–29.
-
-
-
-
42
-
-
85114539425
-
-
Shukla, V.K. and Lemaire, S., Non-opioid effects of dynorphins: possible role of the NMDA receptor, Trends Pharmacol. Sci., 15 (1994) 420–424.
-
-
-
-
43
-
-
85114535482
-
-
Skilling, S.R., Sun, X., Kurtz, H.J. and Larson, A.A., Selective potentiation of NMDA-induced activity and release of excitatory amino acids by dynorphin: possible roles in paralysis and neurotoxicity, Brain Res., 575 (1992) 272–278.
-
-
-
-
44
-
-
85114546575
-
-
Stevens, C.W. and Yaksh, T.L., Dynorphin A and related peptides administered intrathecally in the rat: a search for putative kappa opiate receptor activity, J. Pharmacol. Exp. Ther., 238 (1986) 833–838.
-
-
-
-
45
-
-
85114545274
-
-
Stewart, P. and Isaac, L., Dynorphin-induced depression of the dorsal root potential in rat spinal cord: a possible mechanism for potentiation of the C-fiber reflex, J. Pharmacol. Exp. Ther., 259 (1991) 608–613.
-
-
-
-
46
-
-
85114542414
-
-
Thornhill, J.A., Gregor, L., Mathison, R. and Pittman, Q., Intrathecal dynorphin A administration causes pressor responses in rats associated with an increased resistance to spinal cord blood flow, Brain Res., 490 (1989) 174–177.
-
-
-
-
47
-
-
85114547425
-
-
Vanderah, T.W., Laughlin, T., Lashbrook, J.M., Nichols, M.L., Wilcox, G.L., Ossipov, M.H., Malan, T.P. and Porreca, F., Single intrathecal injections of dynorphin A or des -TYR-dynorphins produce long-lasting allodynia in rats: blockade by MK-801 but not naloxone, Pain, 68 (1996) 275–281.
-
-
-
-
48
-
-
85114545086
-
-
Willenbring, S. and Stevens, C.W., Thermal, mechanical and chemical peripheral sensation in amphibians: opioid and adrenergic effects, Life Sci., 58 (1996) 125–133.
-
-
-
-
49
-
-
85114550262
-
-
Woolf, C.J. and Thompson, S.W., The induction and maintenance of central sensitization is dependent on N -methyl- d -aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states, Pain, 44 (1991) 293–299.
-
-
-
-
50
-
-
85114546612
-
-
Yaksh, T.L., Behavioral and autonomic correlates of the tactile evoked allodynia produced by spinal glycine inhibition: effects of modulatory receptor systems and excitatory amino acid antagonist, Pain, 37 (1989) 111–123.
-
-
-
-
51
-
-
85114529474
-
-
Yaksh, T.L. and Harty, G.J., Pharmacology of the allodynia in rats evoked by high dose intrathecal morphine, J. Pharmacol. Exp. Ther., 244 (1988) 501–507.
-
-
-
-
52
-
-
85114542880
-
-
Yaksh, T.L., Harty, G.J. and Onofrio, B.M., High dose of spinal morphine produces a non-opiate receptor-mediated hyperesthesia: clinical and theoretic implications, Anesthesiology, 64 (1986) 590–597.
-
-
-
-
53
-
-
85114545480
-
-
Yamamoto, T. and Yaksh, T.L, Effects of intrathecal strychnine and bicuculline on nerve compression-induced thermal hyperalgesia and selective antagonism by MK-801, Pain, 54 (1993) 79–84.
-
-
-
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