HIV-1 gp120 stimulates proinflammatory cytokine-mediated pain facilitation via activation of nitric oxide synthase-I (nNOS)

Pain

Volumn 110, Issue 3, 2004, Pages 517-530

  Holguin, Adelina ^a   O'Connor, Kevin A ^a   Biedenkapp, Joseph ^a   Campisi, Jay ^a   Wieseler Frank, Julie ^a   Milligan, Erin D ^a   Hansen, Michael K ^a   Spataro, Leah ^a   Maksimova, Elena ^a   Bravmann, Courtenay ^a   Martin, David ^b   Fleshner, Monika ^a   Maier, Steven F ^a   Watkins, Linda R ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b AMGEN INC   (United States)

Author keywords

Allodynia; Astrocytes; Interleukin 1; Interleukin 6; Microglia; Tumor necrosis factor

Indexed keywords

7 NITROINDAZOLE SODIUM; CYTOKINE; ENZYME; GELATINASE B; GLYCOPROTEIN GP 120; INTERLEUKIN 1 CONVERTING ENZYME; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; N(G) NITROARGININE METHYL ESTER; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG SELECTIVITY; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN IMMUNODEFICIENCY VIRUS 1; LUMBAR SPINAL CORD; MALE; MECHANICS; NONHUMAN; PAIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; PROVOCATION TEST; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINE; STIMULATION;

ANIMALS; CYTOKINES; ENZYME ACTIVATION; HIV ENVELOPE PROTEIN GP120; INFLAMMATION MEDIATORS; MALE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; PAIN; RATS; RATS, SPRAGUE-DAWLEY;

EID: 3843103991     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2004.02.018     Document Type: Article

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