Intrathecal high-dose morphine induces spinally-mediated behavioral responses through NMDA receptors

Molecular Brain Research

Volumn 98, Issue 1-2, 2002, Pages 111-118

  Sakurada, Tsukasa ^a   Watanabe, Chizuko ^b   Okuda, Kazuhiro ^c   Sugiyama, Akinori ^b   Moriyama, Tomoko ^a   Sakurada, Chikai ^a   Tan No, Koichi ^b   Sakurada, Shinobu ^b  

^a DAIICHI UNIVERSITY OF PHARMACY   (Japan)

^b TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

^c FUKUOKA UNIVERSITY   (Japan)

Author keywords

High dose morphine; Intrathecal injection; Mouse spinal cord; NMDA receptor; Scratching, biting and licking

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 3 AMINO 1 HYDROXY 2 PYRROLIDINONE; 4 (3 PHOSPHONOPROPYL) 2 PIPERAZINECARBOXYLIC ACID; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; DIZOCILPINE; IFENPRODIL; MORPHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NALOXONE; OPIATE RECEPTOR;

ANIMAL BEHAVIOR; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG MEGADOSE; DRUG POTENCY; LATENT PERIOD; LICKING; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCRATCHING;

2-AMINO-5-PHOSPHONOVALERATE; 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ANIMALS; BINDING, COMPETITIVE; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; GLUTAMIC ACID; HINDLIMB; HYPERALGESIA; INJECTIONS, SPINAL; MALE; MICE; MICE, MUTANT STRAINS; MORPHINE; NALOXONE; NARCOTIC ANTAGONISTS; NERVE TISSUE PROTEINS; PAIN MEASUREMENT; PIPERAZINES; PIPERIDINES; PYRROLIDINONES; REACTION TIME; RECEPTORS, N-METHYL-D-ASPARTATE; RECEPTORS, OPIOID; SPINAL CORD; SUBARACHNOID SPACE;

EID: 0037203852     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(01)00332-1     Document Type: Article

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