Activation of the spinal ERK signaling pathway contributes naloxone-precipitated withdrawal in morphine-dependent rats

Pain

Volumn 118, Issue 3, 2005, Pages 336-349

  Cao, Jun Li ^a,b   He, Jian Hua ^b   Ding, Hai Lei ^c   Zeng, Yin Ming ^a,b  

^a XUZHOU MEDICAL UNIVERSITY   (China)

^b Jiangsu Institute of Anesthesiology   (China)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Allodynia; cAMP response element binding protein; Extracellular signal regulated kinase; Morphine dependence; Sensitization; Spinal cord; Substance withdrawal syndrome

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ANTISENSE OLIGONUCLEOTIDE; CHELERYTHRINE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DIZOCILPINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MORPHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NALOXONE; PROTEIN FOS; PROTEIN KINASE C INHIBITOR;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG WITHDRAWAL; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; MALE; MORPHINE ADDICTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SENSITIZATION; SIGNAL TRANSDUCTION; SPINAL CORD;

ANIMALS; BUTADIENES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; MALE; MAP KINASE SIGNALING SYSTEM; MORPHINE DEPENDENCE; NALOXONE; NITRILES; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 28644433404     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2005.09.006     Document Type: Article

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