Intrathecal HIV-1 envelope glycoprotein gp120 induces enhanced pain states mediated by spinal cord proinflammatory cytokines

Journal of Neuroscience

Volumn 21, Issue 8, 2001, Pages 2808-2819

  Milligan, Erin D ^a   O'Connor, Kevin A ^a   Nguyen, Kien T ^a   Armstrong, Charles B ^a   Twining, Carin ^a   Gaykema, Ron P A ^a   Holguin, Adelina ^a   Martin, David ^b   Maier, Steven F ^a   Watkins, Linda R ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b AMGEN INC   (United States)

Author keywords

Astrocytes; Hargreaves test; Interleukin 1; Mechanical allodynia; Microglia; Rats; Thermal hyperalgesia; Tumor necrosis factor; Von Frey test

Indexed keywords

CYTOKINE; FLUOROCITRIC ACID; GLYCOPROTEIN GP 120; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA; VIRUS ENVELOPE PROTEIN;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CONTROLLED STUDY; CYTOKINE RELEASE; GLIA CELL; HYPERALGESIA; MALE; MICROGLIA; NONHUMAN; PAIN; PAIN THRESHOLD; PRIORITY JOURNAL; RAT; SPINAL CORD; TACTILE STIMULATION;

EID: 0035871357     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-08-02808.2001     Document Type: Article

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