Comparative integromics on non-canonical WNT or planar cell polarity signaling molecules: Transcriptional mechanism of PTK7 in colorectal cancer and that of SEMA6A in undifferentiated ES cells

International Journal of Molecular Medicine

Volumn 20, Issue 3, 2007, Pages 405-409

  Katoh, Masuko ^a   Katoh, Masaru ^b  

^a M&M Medical BioInformatics   (Japan)

^b NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

Bioinformatics; Frizzled; Integrome network; Invasion; Metastasis; Planar cell polarity; Systems medicine; WNT

Indexed keywords

CELL ADHESION MOLECULE; DNA; PROTEIN TYROSINE KINASE; PTK7 PROTEIN, HUMAN; SEMA6A PROTEIN, HUMAN; SEMAPHORIN; UNCLASSIFIED DRUG; WNT PROTEIN;

ADULT; ANIMAL; ARTICLE; BINDING SITE; BIOLOGICAL MODEL; CELL DIFFERENTIATION; CELL POLARITY; COLORECTAL TUMOR; COMPARATIVE STUDY; CYTOLOGY; EMBRYONIC STEM CELL; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; GENETICS; GENOMICS; HUMAN; INTRON; MACACA; METABOLISM; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; PAN TROGLODYTES; PATHOLOGY; RAT; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; SPECIES DIFFERENCE;

ADULT; ANIMALS; BASE SEQUENCE; BINDING SITES; CELL ADHESION MOLECULES; CELL DIFFERENTIATION; CELL POLARITY; COLORECTAL NEOPLASMS; CONSERVED SEQUENCE; DNA; EMBRYONIC STEM CELLS; GENE EXPRESSION PROFILING; GENOMICS; HUMANS; INTRONS; MACACA MULATTA; MICE; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PAN TROGLODYTES; RATS; RECEPTOR PROTEIN-TYROSINE KINASES; SEMAPHORINS; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; SPECIES SPECIFICITY; TRANSCRIPTION, GENETIC; WNT PROTEINS;

EID: 35148848262     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.20.3.405     Document Type: Article

References (54)

1. Katoh M and Katoh M: WNT signaling pathway and stem cell signaling network. Clin Cancer Res (In press).
2. Swain RK, Katoh M, Medina A and Steinbeisser H: Xenopus frizzled-4S, a splicing variant of Xfz4, is a context-dependent activator and inhibitor of Wnt/β-catenin signaling. Cell Commun Signal 3: 12, 2005.
3. Katoh M and Katoh M: STAT3-induced WNT5A signaling loop in embryonic stem cells, adult normal tissues, chronic persistent inflammation, rheumatoid arthritis, and cancer. Int J Mol Med 19: 273-278, 2007.
4. He TC, Sparks AB, Rago C, et al: Identification of c-MYC as a target of the APC pathway. Science 281: 1509-1512, 1998.
5. Tetsu O and McCormick F: β-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 398: 422-426, 1999.
6. Katoh M and Katoh M: Comparative genomics on FGF20 orthologs. Oncol Rep 14: 287-290, 2005.
7. Katoh M and Katoh M: Crosstalk of WNT and FGF signaling pathways at GSK3β to regulate β-catenin and SNAIL signaling cascades. Cancer Biol Ther 5: 1059-1064, 2006.
8. Pennica D, Swanson TA, Welsh JW, et al: WISP genes are members of the connective tissue growth factor family that are up-regulated in Wnt1-transformed cells and aberrantly expressed in human colon tumors. Proc Natl Acad Sci USA 95: 14717-14722, 1998.
9. Katoh M and Katoh M: Notch ligand, JAG1, is evolutionarily conserved target of canonical WNT signaling pathway in progenitor cells. Int J Mol Med 17: 681-685, 2006.
10. Chamorro MN, Schwartz DR, Vonica A, et al: FGF20 and DKK1 are transcriptional target of β-catenin and FGF20 is implicated in cancer and development. EMBO J 24: 73-84, 2005.
11. Yi F, Brubaker PL and Jin T: TCF-4 mediates cell type-specific regulation of proglucagon gene expression by β-catenin and glycogen synthase kinase-3β. J Biol Chem 280: 1457-1464, 2005.
12. Boutros M, Paricio N, Strutt DI, et al: Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling. Cell 94: 109-118, 1998.
13. 2+- induced NFAT activity is counteracted by Wnt-5a/Yes-Cdc42-casein kinase Ia signaling in human mammary epithelial cells. Mol Cell Biol 26: 6024-6036, 2006.
14. Katoh M: WNT/PCP signaling pathway and human cancer. Oncol Rep 14: 1583-1588, 2005.
15. Myers DC, Sepich DS and Solnica-Krezel L: Convergence and extension in vertebrate gastrulae: cell movements according to or in search of identity. Trends Genet 18: 447-455, 2002.
16. Keller R: Shaping the vertebrate body plan by polarized embryonic cell movements. Science 298: 1950-1954, 2002.
17. Montcouquiol M, Rachel RA, Lanford PJ, et al: Identification of Vangl2 and Scrib1 as planar polarity genes in mammals. Nature 423: 173-177, 2003.
18. Toyofuku T, Zhang H, Kumanogoh A, et al: Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2. Genes Dev 18: 435-447, 2004.
19. Suto F, Ito K, Uemura M, et al: Plexin-a4 mediates axon-repulsive activities of both secreted and transmembrane semaphorins and plays roles in nerve fiber guidance. J Neurosci 25: 3628-3637, 2005.
20. Guo N, Hawkins C and Nathans J: Frizzled6 controls hair patterning in mice. Proc Natl Acad Sci USA 101: 9277-9281, 2004.
21. Lu W, Yamamoto V, Ortega B and Baltimore D: Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth. Cell 119: 97-108, 2004.
22. Curtin JA, Quint E, Tsipouri V, et al: Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse. Curr Biol 13: 1129-1133, 2003.
23. Lu X, Borchers AG, Jolicoeur C, et al: PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates. Nature 430: 93-98, 2004.
24. Saitoh T and Katoh M: Frequent up-regulation of WNT5A mRNA in primary gastric cancer. Int J Mol Med 9: 515-519, 2002.
25. Weeraratna AT, Jiang Y, Hostetter G, et al: Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma. Cancer Cell 1: 279-288, 2002.
26. Saitoh T and Katoh M: Molecular cloning and characterization of human WNT5B on chromosome 12p13.3 region. Int J Oncol 19: 347-351, 2001.
27. Kirikoshi H, Sekihara H and Katoh M: Molecular cloning and characterization of human WNT11. Int J Mol Med 8: 651-656, 2001.
28. Kirikoshi H, Koike J, Sagara N, Saitoh T, Tokuhara M, Tanaka K, Sekihara H, Hirai M and Katoh M: Molecular cloning and genomic structure of human Frizzled-3 at chromosome 8p21. Biochem Biophys Res Commun 271: 8-14, 2000. (Pubitemid 30444848)
29. Tokuhara M, Hirai M, Atomi Y, Terada M and Katoh M: Molecular cloning and characterization of human Frizzled-6. Biochem Biophys Res Commun 243: 622-627, 1998.
30. Katoh M: Molecular cloning and characterization of Strabismus 2 (STB2). Int J Oncol 20: 993-998, 2002.
31. Katoh M: Structure and expression of Strabismus 1 (STB1) gene on human chromosome 1q21-q23. Int J Oncol 20: 1197-1203, 2002.
32. Katoh M: Strabismus (STB)/Vang-like (Vangl) gene family. Int J Mol Med 10: 11-15, 2002.
33. Katoh M and Katoh M: Identification and characterization of human PRICKLE1 and PRICKLE2 genes as well as mouse Prickle1 and Prickle2 genes homologous to Drosophila tissue polarity gene prickle. Int J Mol Med 11: 249-256, 2003.
34. Clark CC, Cohen I, Eichstetter I, et al: Molecular cloning of the human proto-oncogene Wnt-5A and mapping of the gene (WNT5A) to chromosome 3p14-p21. Genomics 18: 249-260, 1993.
35. Masiakowski P and Carroll RD: A novel family of cell surface receptors with tyrosine kinase-like domain. J Biol Chem 267: 26181-26190, 1992.
36. Stacker SA, Hovens CM, Vitali A, et al: Molecular cloning and chromosomal localisation of the human homologue of a receptor related to tyrosine kinases (RYK). Oncogene 8: 1347-1356, 1993.
37. Hadjantonakis AK, Sheward WJ, Harmar AJ, et al: Celsr1, a neural-specific gene encoding an unusual seven-pass transmembrane receptor, maps to mouse chromosome 15 and human chromosome 22qter. Genomics 45: 97-104, 1997.
38. Wu Q and Maniatis T: A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell 97: 779-790, 1999.
39. Mossie K, Jallal B, Alves F, et al: Colon carcinoma kinase-4 defines a new subclass of the receptor tyrosine kinase family. Oncogene 11: 2179-2184, 1995.
40. Correa RG, Sasahara RM, Bengtson MH, et al: Human semaphorin 6B, a novel human class 6 semaphorin gene: alternative splicing and all-trans-retinoic acid-dependent downregulation in glioblastoma cell lines. Genomics 73: 343-348, 2001.
41. Qu X, Wei H, Zhai Y, et al: Identification, characterization, and functional study of the two novel human members of the semaphorin gene family. J Biol Chem 277: 35574-35585, 2002.
42. Katoh M: Paradignshift in gene-finding method: From bench-top approach to desk-top approach. Int J Mol Med 10: 677-682, 2002.
43. Katoh M and Katoh M: AP1- and NF-κB-binding sites conserved among mammalian WNT10B orthologs elucidate the TNFα-WNT10B signaling loop implicated in carcinogenesis and adipogenesis. Int J Mol Med 19: 699-703, 2007.
44. Katoh M and Katoh M: Comparative integromics on FZD7 orthologs: Conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'promoter region of mammalian FZD7 orthologs. Int J Mol Med 19: 529-533, 2007.
45. Katoh Y and Katoh M: Comparative genomics on VANGL1 and VANGL2 genes. Int J Oncol 26: 1435-1440, 2005.
46. Katoh M and Katoh M: Identification and characterization of human FMNL1, FMNL2 and FMNL3 genes in silico. Int J Oncol 22: 1161-1168, 2003.
47. Katoh M and Katoh M: Identification and characterization of human BCL9L gene and mouse Bcl9l gene in silico. Int J Mol Med 12: 643-649, 2003.
48. Katoh M and Katoh M: Identification and characterization of human HES2, HES3, and HES5 genes in silico. Int J Oncol 25: 529-534, 2004.
49. Katoh M and Katoh M: WNT antagonist, DKK2, is Notch signaling target in intestinal stem cells: Augmentation of negative regulation system for canonical WNT signaling pathway by Notch-DKK2 signaling loop in primates. Int J Mol Med 19: 197-201, 2007.
50. Katoh Y and Katoh M: Conserved POU-binding site linked to SP1-binding site within FZD5 promoter: Transcriptional mechanisms of FZD5 in undifferentiated human ES cells, fetal liver/spleen, adult colon, pancreatic islet, and diffuse-type gastric cancer. Int J Oncol 30: 751-755, 2007.
51. Katoh M and Katoh M: Conserved POU/OCT- and GATA-binding sites in 5′-flanking promoter region of mammalian WNT8B orthologs. Int J Oncol 30: 1273-1277, 2007.
52. Katoh M: Networking of WNT, FGF, Notch, BMP, and Hedgehog signaling pathways during carcinogenesis. Stem Cell Rev (In press).
53. Katoh M: Dysregulation of stem cell signaling network due to germline mutation, SNP, Helicobacter pylori infection, epigenetic change, and genetic alteration in gastric cancer. Cancer Biol Ther (In press).
54. Boudeau J, Miranda-Saavedra D, Barton GJ and Alessi DR: Emerging roles of pseudokinases. Trends Cell Biol 16: 443-452, 2006.