Characterization of the Cofactor-Induced Folding Mechanism of a Zinc-Binding Peptide Using Computationally Designed Mutants

Journal of Molecular Biology

Volumn 389, Issue 1, 2009, Pages 90-102

  Tang, Jia ^a   Kang, Seung Gu ^a   Saven, Jeffery G ^a   Gai, Feng ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

computational design; folding intermediate; protein folding; stopped flow fluorescence; zinc binding peptides

Indexed keywords

CH1 PEPTIDE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; CYSTEINE; HISTIDINE; LIGAND; MUTANT PROTEIN; PEPTIDE; TRYPTOPHAN; UNCLASSIFIED DRUG; ZINC BINDING PROTEIN; ZINC COMPLEX; ZINC ION;

ARTICLE; BINDING AFFINITY; COMPUTER AIDED DESIGN; FLUORESCENCE; KINETICS; METAL BINDING; MUTATION; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN MOTIF; TEMPERATURE DEPENDENCE;

EID: 67349280175     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2009.03.074     Document Type: Article

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