Mechanical stimulus alters conformation of type 1 parathyroid hormone receptor in bone cells

American Journal of Physiology - Cell Physiology

Volumn 296, Issue 6, 2009, Pages

  Zhang, Yan Liang ^a   Frangos, John A ^a   Chachisvilis, Mirianas ^a  

^a LA JOLLA BIOENGINEERING INSTITUTE   (United States)

Author keywords

Fluid shear stress; Fluorescence resonance energy transfer; G protein coupled receptor; Mechanosensor; Mechanotransduction

Indexed keywords

G PROTEIN COUPLED RECEPTOR; PARATHYROID HORMONE RECEPTOR 1;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BONE CELL; CELL MEMBRANE; CONTROLLED STUDY; FLUORESCENCE MICROSCOPY; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENETIC ENGINEERING; HUMAN; HUMAN CELL; MECHANICAL STIMULATION; MECHANICAL STRESS; MEMBRANE FLUIDITY; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SHEAR STRESS; SIGNAL TRANSDUCTION;

ANIMALS; BIOSENSING TECHNIQUES; CATTLE; CELL LINE; CELL MEMBRANE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; LIGANDS; MECHANOTRANSDUCTION, CELLULAR; MEMBRANE FLUIDITY; MICE; MICROSCOPY, FLUORESCENCE; OSTEOBLASTS; PARATHYROID HORMONE; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; RECEPTOR, PARATHYROID HORMONE, TYPE 1; STRESS, MECHANICAL; TIME FACTORS; TRANSFECTION;

MURINAE;

EID: 66749151000     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00549.2008     Document Type: Article

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