Conformational switch of angiotensin II type 1 receptor underlying mechanical stress-induced activation

EMBO Reports

Volumn 9, Issue 2, 2008, Pages 179-186

  Yasuda, Noritaka ^a   Miura, Shin Ichiro ^b   Akazawa, Hiroshi ^a   Tanaka, Toshimasa ^c   Qin, Yingjie ^a   Kiya, Yoshihiro ^b   Imaizumi, Satoshi ^b   Fujino, Masahiro ^b   Ito, Kaoru ^a   Zou, Yunzeng ^d   Fukuhara, Shigetomo ^e   Kunimoto, Satoshi ^e   Fukuzaki, Koichi ^a   Sato, Toshiaki ^a   Ge, Junbo ^d   Mochizuki, Naoki ^e   Nakaya, Haruaki ^a   Saku, Keijiro ^b   Komuro, Issei ^a  

^a CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b FUKUOKA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

^d FUDAN UNIVERSITY   (China)

^e NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; CANDESARTAN; CARBOXYL GROUP; G PROTEIN COUPLED RECEPTOR;

ARTICLE; CONTROLLED STUDY; GENE ACTIVATION; GENE REPRESSION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LIGAND BINDING; MECHANICAL STRESS; MOLECULAR MODEL; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; RECEPTOR BINDING;

BENZIMIDAZOLES; CELL LINE; HUMANS; MODELS, MOLECULAR; PROTEIN STRUCTURE, SECONDARY; RECEPTOR, ANGIOTENSIN, TYPE 1; ROTATION; STRESS, MECHANICAL; TETRAZOLES;

EID: 38949137039     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/sj.embor.7401157     Document Type: Article

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