메뉴 건너뛰기




Volumn 15, Issue 10, 2009, Pages 1201-1208

Hepatitis C virus and ethanol alter antigen presentation in liver cells

Author keywords

Alcohol; Antigen presentation; Hepatitis C Virus; Interferon alpha and gamma; Liver; Major histocompatibility complex (MHC) class; MHC class

Indexed keywords

ALCOHOL; ALPHA INTERFERON; AMINOPEPTIDASE; GAMMA INTERFERON; INTERLEUKIN 10; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROTEASOME; STAT1 PROTEIN; STAT2 PROTEIN; TOLL LIKE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2;

EID: 65649104016     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.15.1201     Document Type: Review
Times cited : (20)

References (102)
  • 2
    • 1042278901 scopus 로고    scopus 로고
    • New insights into pathways for CD1-mediated antigen presentation
    • Sugita M, Cernadas M, Brenner MB. New insights into pathways for CD1-mediated antigen presentation. Curr Opin Immunol 2004; 16: 90-95
    • (2004) Curr Opin Immunol , vol.16 , pp. 90-95
    • Sugita, M.1    Cernadas, M.2    Brenner, M.B.3
  • 3
    • 0031155385 scopus 로고    scopus 로고
    • Perforin, Fas/Fas ligand, and TNF-alpha pathways as specific and bystander killing mechanisms of hepatitis C virus-specific human CTL
    • Ando K, Hiroishi K, Kaneko T, Moriyama T, Muto Y, Kayagaki N, Yagita H, Okumura K, Imawari M. Perforin, Fas/Fas ligand, and TNF-alpha pathways as specific and bystander killing mechanisms of hepatitis C virus-specific human CTL. J Immunol 1997; 158: 5283-5291
    • (1997) J Immunol , vol.158 , pp. 5283-5291
    • Ando, K.1    Hiroishi, K.2    Kaneko, T.3    Moriyama, T.4    Muto, Y.5    Kayagaki, N.6    Yagita, H.7    Okumura, K.8    Imawari, M.9
  • 4
    • 0037277436 scopus 로고    scopus 로고
    • HCV immunology-death and the maiden T cell
    • Willberg C, Barnes E, Klenerman P. HCV immunology-death and the maiden T cell. Cell Death Differ 2003; 10 Suppl 1: S39-S47
    • (2003) Cell Death Differ , vol.10 , Issue.SUPPL. 1
    • Willberg, C.1    Barnes, E.2    Klenerman, P.3
  • 5
    • 33645038201 scopus 로고    scopus 로고
    • Immunopathogenesis of hepatitis C virus infection: Multifaceted strategies subverting innate and adaptive immunity
    • Kanto T, Hayashi N. Immunopathogenesis of hepatitis C virus infection: multifaceted strategies subverting innate and adaptive immunity. Intern Med 2006; 45: 183-191
    • (2006) Intern Med , vol.45 , pp. 183-191
    • Kanto, T.1    Hayashi, N.2
  • 6
    • 40749113642 scopus 로고    scopus 로고
    • Alcohol, cofactors and the genetics of hepatocellular carcinoma
    • Yu MC, Yuan JM, Lu SC. Alcohol, cofactors and the genetics of hepatocellular carcinoma. J Gastroenterol Hepatol 2008; 23 Suppl 1: S92-S97
    • (2008) J Gastroenterol Hepatol , vol.23 , Issue.SUPPL. 1
    • Yu, M.C.1    Yuan, J.M.2    Lu, S.C.3
  • 8
    • 33644544110 scopus 로고    scopus 로고
    • The liver as an immunological organ
    • Racanelli V, Rehermann B. The liver as an immunological organ. Hepatology 2006; 43: S54-S62
    • (2006) Hepatology , vol.43
    • Racanelli, V.1    Rehermann, B.2
  • 9
    • 0034031683 scopus 로고    scopus 로고
    • Local control of the immune response in the liver
    • Knolle PA, Gerken G. Local control of the immune response in the liver. Immunol Rev 2000; 174: 21-34
    • (2000) Immunol Rev , vol.174 , pp. 21-34
    • Knolle, P.A.1    Gerken, G.2
  • 10
    • 51349131121 scopus 로고    scopus 로고
    • Mechanism of T cell tolerance induction by murine hepatic Kupffer cells
    • You Q, Cheng L, Kedl RM, Ju C. Mechanism of T cell tolerance induction by murine hepatic Kupffer cells. Hepatology 2008; 48: 978-990
    • (2008) Hepatology , vol.48 , pp. 978-990
    • You, Q.1    Cheng, L.2    Kedl, R.M.3    Ju, C.4
  • 11
    • 0031768675 scopus 로고    scopus 로고
    • IL-10 down-regulates T cell activation by antigen-presenting liver sinusoidal endothelial cells through decreased antigen uptake via the mannose receptor and lowered surface expression of accessory molecules
    • Knolle PA, Uhrig A, Hegenbarth S, Loser E, Schmitt E, Gerken G, Lohse AW. IL-10 down-regulates T cell activation by antigen-presenting liver sinusoidal endothelial cells through decreased antigen uptake via the mannose receptor and lowered surface expression of accessory molecules. Clin Exp Immunol 1998; 114: 427-433
    • (1998) Clin Exp Immunol , vol.114 , pp. 427-433
    • Knolle, P.A.1    Uhrig, A.2    Hegenbarth, S.3    Loser, E.4    Schmitt, E.5    Gerken, G.6    Lohse, A.W.7
  • 14
  • 16
    • 0037302569 scopus 로고    scopus 로고
    • Dendritic cells and immune regulation in the liver
    • Lau AH, Thomson AW. Dendritic cells and immune regulation in the liver. Gut 2003; 52: 307-314
    • (2003) Gut , vol.52 , pp. 307-314
    • Lau, A.H.1    Thomson, A.W.2
  • 17
    • 0035135264 scopus 로고    scopus 로고
    • Induction of cytokine production and proliferation of memory lymphocytes by murine liver dendritic cell progenitors: Role of these progenitors as immunogenic resident antigen-presenting cells in the liver
    • Abe M, Akbar SM, Horiike N, Onji M. Induction of cytokine production and proliferation of memory lymphocytes by murine liver dendritic cell progenitors: role of these progenitors as immunogenic resident antigen-presenting cells in the liver. J Hepatol 2001; 34: 61-67
    • (2001) J Hepatol , vol.34 , pp. 61-67
    • Abe, M.1    Akbar, S.M.2    Horiike, N.3    Onji, M.4
  • 18
    • 0032979846 scopus 로고    scopus 로고
    • Are dendritic cells the key to liver transplant tolerance?
    • Thomson AW, Lu L. Are dendritic cells the key to liver transplant tolerance? Immunol Today 1999; 20: 27-32
    • (1999) Immunol Today , vol.20 , pp. 27-32
    • Thomson, A.W.1    Lu, L.2
  • 19
    • 0030758485 scopus 로고    scopus 로고
    • The influence of collagen, fibronectin, and laminin on the maturation of dendritic cell progenitors propagated from normal or Flt3-ligand-treated mouse liver
    • Drakes ML, Lu L, McKenna HJ, Thomson AW. The influence of collagen, fibronectin, and laminin on the maturation of dendritic cell progenitors propagated from normal or Flt3-ligand-treated mouse liver. Adv Exp Med Biol 1997; 417: 115-120
    • (1997) Adv Exp Med Biol , vol.417 , pp. 115-120
    • Drakes, M.L.1    Lu, L.2    McKenna, H.J.3    Thomson, A.W.4
  • 20
    • 37749031215 scopus 로고    scopus 로고
    • Dendritic cells, the liver, and transplantation
    • Sumpter TL, Abe M, Tokita D, Thomson AW. Dendritic cells, the liver, and transplantation. Hepatology 2007; 46: 2021-2031
    • (2007) Hepatology , vol.46 , pp. 2021-2031
    • Sumpter, T.L.1    Abe, M.2    Tokita, D.3    Thomson, A.W.4
  • 21
    • 33846261199 scopus 로고    scopus 로고
    • Ito cells, stellate cells, and myofibroblasts: New actors in antigen presentation
    • Unanue ER. Ito cells, stellate cells, and myofibroblasts: new actors in antigen presentation. Immunity 2007; 26: 9-10
    • (2007) Immunity , vol.26 , pp. 9-10
    • Unanue, E.R.1
  • 22
    • 0034078355 scopus 로고    scopus 로고
    • The liver as a site of T-cell apoptosis: Graveyard, or killing field?
    • Crispe IN, Dao T, Klugewitz K, Mehal WZ, Metz DP. The liver as a site of T-cell apoptosis: graveyard, or killing field? Immunol Rev 2000; 174: 47-62
    • (2000) Immunol Rev , vol.174 , pp. 47-62
    • Crispe, I.N.1    Dao, T.2    Klugewitz, K.3    Mehal, W.Z.4    Metz, D.P.5
  • 23
    • 22544438678 scopus 로고    scopus 로고
    • Liver inflammation and regeneration: Two distinct biological phenomena or parallel pathophysiologic processes?
    • Markiewski MM, DeAngelis RA, Lambris JD. Liver inflammation and regeneration: two distinct biological phenomena or parallel pathophysiologic processes? Mol Immunol 2006; 43: 45-56
    • (2006) Mol Immunol , vol.43 , pp. 45-56
    • Markiewski, M.M.1    DeAngelis, R.A.2    Lambris, J.D.3
  • 25
    • 33746190823 scopus 로고    scopus 로고
    • Local intrahepatic CD8+ T cell activation by a non-self-antigen results in full functional differentiation
    • Wuensch SA, Pierce RH, Crispe IN. Local intrahepatic CD8+ T cell activation by a non-self-antigen results in full functional differentiation. J Immunol 2006; 177: 1689-1697
    • (2006) J Immunol , vol.177 , pp. 1689-1697
    • Wuensch, S.A.1    Pierce, R.H.2    Crispe, I.N.3
  • 26
    • 33845427947 scopus 로고    scopus 로고
    • Cytotoxic T-cell response following mouse liver transplantation is independent of the initial site of T-cell priming
    • Klein I, Gassel HJ, Crispe IN. Cytotoxic T-cell response following mouse liver transplantation is independent of the initial site of T-cell priming. Transplant Proc 2006; 38: 3241-3243
    • (2006) Transplant Proc , vol.38 , pp. 3241-3243
    • Klein, I.1    Gassel, H.J.2    Crispe, I.N.3
  • 27
    • 55749106392 scopus 로고    scopus 로고
    • Post-apoptotic tumors are more palatable to dendritic cells and enhance their antigen crosspresentation activity
    • Brusa D, Garetto S, Chiorino G, Scatolini M, Migliore E, Camussi G, Matera L. Post-apoptotic tumors are more palatable to dendritic cells and enhance their antigen crosspresentation activity. Vaccine 2008; 26: 6422-6432
    • (2008) Vaccine , vol.26 , pp. 6422-6432
    • Brusa, D.1    Garetto, S.2    Chiorino, G.3    Scatolini, M.4    Migliore, E.5    Camussi, G.6    Matera, L.7
  • 28
    • 52449099804 scopus 로고    scopus 로고
    • MHC class I endosomal and lysosomal trafficking coincides with exogenous antigen loading in dendritic cells
    • Basha G, Lizee G, Reinicke AT, Seipp RP, Omilusik KD, Jefferies WA. MHC class I endosomal and lysosomal trafficking coincides with exogenous antigen loading in dendritic cells. PLoS ONE 2008; 3: e3247
    • (2008) PLoS ONE , vol.3
    • Basha, G.1    Lizee, G.2    Reinicke, A.T.3    Seipp, R.P.4    Omilusik, K.D.5    Jefferies, W.A.6
  • 30
    • 0036777957 scopus 로고    scopus 로고
    • The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides
    • Goldberg AL, Cascio P, Saric T, Rock KL. The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides. Mol Immunol 2002; 39: 147-164
    • (2002) Mol Immunol , vol.39 , pp. 147-164
    • Goldberg, A.L.1    Cascio, P.2    Saric, T.3    Rock, K.L.4
  • 31
    • 0032488846 scopus 로고    scopus 로고
    • The proteasome: Paradigm of a self-compartmentalizing protease
    • Baumeister W, Walz J, Zuhl F, Seemuller E. The proteasome: paradigm of a self-compartmentalizing protease. Cell 1998; 92: 367-380
    • (1998) Cell , vol.92 , pp. 367-380
    • Baumeister, W.1    Walz, J.2    Zuhl, F.3    Seemuller, E.4
  • 35
    • 0030886208 scopus 로고    scopus 로고
    • Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide
    • Craiu A, Akopian T, Goldberg A, Rock KL. Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide. Proc Natl Acad Sci USA 1997; 94: 10850-10855
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10850-10855
    • Craiu, A.1    Akopian, T.2    Goldberg, A.3    Rock, K.L.4
  • 36
    • 1042278905 scopus 로고    scopus 로고
    • Proteasome and peptidase function in MHC-class-I-mediated antigen presentation
    • Kloetzel PM, Ossendorp F. Proteasome and peptidase function in MHC-class-I-mediated antigen presentation. Curr Opin Immunol 2004; 16: 76-81
    • (2004) Curr Opin Immunol , vol.16 , pp. 76-81
    • Kloetzel, P.M.1    Ossendorp, F.2
  • 37
    • 0035873704 scopus 로고    scopus 로고
    • 26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide
    • Cascio P, Hilton C, Kisselev AF, Rock KL, Goldberg AL. 26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide. EMBO J 2001; 20: 2357-2366
    • (2001) EMBO J , vol.20 , pp. 2357-2366
    • Cascio, P.1    Hilton, C.2    Kisselev, A.F.3    Rock, K.L.4    Goldberg, A.L.5
  • 38
    • 0036884090 scopus 로고    scopus 로고
    • The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues
    • York IA, Chang SC, Saric T, Keys JA, Favreau JM, Goldberg AL, Rock KL. The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues. Nat Immunol 2002; 3: 1177-1184
    • (2002) Nat Immunol , vol.3 , pp. 1177-1184
    • York, I.A.1    Chang, S.C.2    Saric, T.3    Keys, J.A.4    Favreau, J.M.5    Goldberg, A.L.6    Rock, K.L.7
  • 39
    • 0030763047 scopus 로고    scopus 로고
    • Presentation of exogenous protein antigens on major histocompatibility complex class I molecules by dendritic cells: Pathway of presentation and regulation by cytokines
    • Brossart P, Bevan MJ. Presentation of exogenous protein antigens on major histocompatibility complex class I molecules by dendritic cells: pathway of presentation and regulation by cytokines. Blood 1997; 90: 1594-1599
    • (1997) Blood , vol.90 , pp. 1594-1599
    • Brossart, P.1    Bevan, M.J.2
  • 40
    • 0031113954 scopus 로고    scopus 로고
    • Virus-mediated delivery of antigenic epitopes into dendritic cells as a means to induce CTL
    • Brossart P, Goldrath AW, Butz EA, Martin S, Bevan MJ. Virus-mediated delivery of antigenic epitopes into dendritic cells as a means to induce CTL. J Immunol 1997; 158: 3270-3276
    • (1997) J Immunol , vol.158 , pp. 3270-3276
    • Brossart, P.1    Goldrath, A.W.2    Butz, E.A.3    Martin, S.4    Bevan, M.J.5
  • 41
    • 0036776739 scopus 로고    scopus 로고
    • MHC class I antigen processing regulated by cytosolic proteolysis-short cuts that alter peptide generation
    • Kessler BM, Glas R, Ploegh HL. MHC class I antigen processing regulated by cytosolic proteolysis-short cuts that alter peptide generation. Mol Immunol 2002; 39: 171-179
    • (2002) Mol Immunol , vol.39 , pp. 171-179
    • Kessler, B.M.1    Glas, R.2    Ploegh, H.L.3
  • 46
    • 38049039851 scopus 로고    scopus 로고
    • Proteasome activator and antigen-processing aminopeptidases are regulated by virus-induced type I interferon in the hepatitis C virus-infected liver
    • Shin EC, Seifert U, Urban S, Truong KT, Feinstone SM, Rice CM, Kloetzel PM, Rehermann B. Proteasome activator and antigen-processing aminopeptidases are regulated by virus-induced type I interferon in the hepatitis C virus-infected liver. J Interferon Cytokine Res 2007; 27: 985-990
    • (2007) J Interferon Cytokine Res , vol.27 , pp. 985-990
    • Shin, E.C.1    Seifert, U.2    Urban, S.3    Truong, K.T.4    Feinstone, S.M.5    Rice, C.M.6    Kloetzel, P.M.7    Rehermann, B.8
  • 48
    • 10644229240 scopus 로고    scopus 로고
    • Hepatitis C virus non-structural protein NS3 interacts with LMP7, a component of the immunoproteasome, and affects its proteasome activity
    • Khu YL, Tan YJ, Lim SG, Hong W, Goh PY. Hepatitis C virus non-structural protein NS3 interacts with LMP7, a component of the immunoproteasome, and affects its proteasome activity. Biochem J 2004; 384: 401-409
    • (2004) Biochem J , vol.384 , pp. 401-409
    • Khu, Y.L.1    Tan, Y.J.2    Lim, S.G.3    Hong, W.4    Goh, P.Y.5
  • 49
    • 44649095826 scopus 로고    scopus 로고
    • Proteasome activation by hepatitis C core protein is reversed by ethanol-induced oxidative stress
    • Osna NA, White RL, Krutik VM, Wang T, Weinman SA, Donohue TM Jr. Proteasome activation by hepatitis C core protein is reversed by ethanol-induced oxidative stress. Gastroenterology 2008; 134: 2144-2152
    • (2008) Gastroenterology , vol.134 , pp. 2144-2152
    • Osna, N.A.1    White, R.L.2    Krutik, V.M.3    Wang, T.4    Weinman, S.A.5    Donohue Jr., T.M.6
  • 50
    • 0035072229 scopus 로고    scopus 로고
    • Degradation of oxidized proteins by the 20S proteasome
    • Davies KJ. Degradation of oxidized proteins by the 20S proteasome. Biochimie 2001; 83: 301-310
    • (2001) Biochimie , vol.83 , pp. 301-310
    • Davies, K.J.1
  • 51
    • 4544304395 scopus 로고    scopus 로고
    • Peroxynitrite alters the catalytic activity of rodent liver proteasome in vitro and in vivo
    • Osna NA, Haorah J, Krutik VM, Donohue TM Jr. Peroxynitrite alters the catalytic activity of rodent liver proteasome in vitro and in vivo. Hepatology 2004; 40: 574-582
    • (2004) Hepatology , vol.40 , pp. 574-582
    • Osna, N.A.1    Haorah, J.2    Krutik, V.M.3    Donohue Jr., T.M.4
  • 52
    • 0041930639 scopus 로고    scopus 로고
    • Interferon gamma enhances proteasome activity in recombinant Hep G2 cells that express cytochrome P4502E1: Modulation by ethanol
    • Osna NA, Clemens DL, Donohue TM Jr. Interferon gamma enhances proteasome activity in recombinant Hep G2 cells that express cytochrome P4502E1: modulation by ethanol. Biochem Pharmacol 2003; 66: 697-710
    • (2003) Biochem Pharmacol , vol.66 , pp. 697-710
    • Osna, N.A.1    Clemens, D.L.2    Donohue Jr., T.M.3
  • 53
    • 25644432064 scopus 로고    scopus 로고
    • The effect of CYP2E1-dependent oxidant stress on activity of proteasomes in HepG2 cells
    • Kessova IG, Cederbaum AI. The effect of CYP2E1-dependent oxidant stress on activity of proteasomes in HepG2 cells. J Pharmacol Exp Ther 2005; 315: 304-312
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 304-312
    • Kessova, I.G.1    Cederbaum, A.I.2
  • 54
    • 33750505407 scopus 로고    scopus 로고
    • CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation
    • Bardag-Gorce F, French BA, Nan L, Song H, Nguyen SK, Yong H, Dede J, French SW. CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation. Exp Mol Pathol 2006; 81: 191-201
    • (2006) Exp Mol Pathol , vol.81 , pp. 191-201
    • Bardag-Gorce, F.1    French, B.A.2    Nan, L.3    Song, H.4    Nguyen, S.K.5    Yong, H.6    Dede, J.7    French, S.W.8
  • 55
    • 13844298275 scopus 로고    scopus 로고
    • The effect of ethanol-induced CYP2E1 on proteasome activity: The role of 4-hydroxynonenal
    • Bardag-Gorce F, Li J, French BA, French SW. The effect of ethanol-induced CYP2E1 on proteasome activity: the role of 4-hydroxynonenal. Exp Mol Pathol 2005; 78: 109-115
    • (2005) Exp Mol Pathol , vol.78 , pp. 109-115
    • Bardag-Gorce, F.1    Li, J.2    French, B.A.3    French, S.W.4
  • 57
    • 1042278900 scopus 로고    scopus 로고
    • Class II MHC peptide loading by the professionals
    • Bryant P, Ploegh H. Class II MHC peptide loading by the professionals. Curr Opin Immunol 2004; 16: 96-102
    • (2004) Curr Opin Immunol , vol.16 , pp. 96-102
    • Bryant, P.1    Ploegh, H.2
  • 58
    • 0037087364 scopus 로고    scopus 로고
    • A role for cathepsin L and cathepsin S in peptide generation for MHC class II presentation
    • Hsieh CS, deRoos P, Honey K, Beers C, Rudensky AY. A role for cathepsin L and cathepsin S in peptide generation for MHC class II presentation. J Immunol 2002; 168: 2618-2625
    • (2002) J Immunol , vol.168 , pp. 2618-2625
    • Hsieh, C.S.1    deRoos, P.2    Honey, K.3    Beers, C.4    Rudensky, A.Y.5
  • 60
    • 0037960005 scopus 로고    scopus 로고
    • Nimmerjahn F, Milosevic S, Behrends U, Jaffee EM, Pardoll DM, Bornkamm GW, Mautner J. Major histocompatibility complex class II-restricted presentation of a cytosolic antigen by autophagy. Eur J Immunol 2003; 33: 1250-1259
    • Nimmerjahn F, Milosevic S, Behrends U, Jaffee EM, Pardoll DM, Bornkamm GW, Mautner J. Major histocompatibility complex class II-restricted presentation of a cytosolic antigen by autophagy. Eur J Immunol 2003; 33: 1250-1259
  • 62
    • 0035903288 scopus 로고    scopus 로고
    • Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens
    • Kadowaki N, Ho S, Antonenko S, Malefyt RW, Kastelein RA, Bazan F, Liu YJ. Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. J Exp Med 2001; 194: 863-869
    • (2001) J Exp Med , vol.194 , pp. 863-869
    • Kadowaki, N.1    Ho, S.2    Antonenko, S.3    Malefyt, R.W.4    Kastelein, R.A.5    Bazan, F.6    Liu, Y.J.7
  • 63
    • 17644372733 scopus 로고    scopus 로고
    • IPC: Professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors
    • Liu YJ. IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. Annu Rev Immunol 2005; 23: 275-306
    • (2005) Annu Rev Immunol , vol.23 , pp. 275-306
    • Liu, Y.J.1
  • 64
    • 59649123419 scopus 로고    scopus 로고
    • Modulation of dendritic cell function by persistent viruses
    • Liu B, Woltman AM, Janssen HL, Boonstra A. Modulation of dendritic cell function by persistent viruses. J Leukoc Biol 2009; 85: 205-214
    • (2009) J Leukoc Biol , vol.85 , pp. 205-214
    • Liu, B.1    Woltman, A.M.2    Janssen, H.L.3    Boonstra, A.4
  • 65
    • 0035121503 scopus 로고    scopus 로고
    • Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection
    • Bain C, Fatmi A, Zoulim F, Zarski JP, Trepo C, Inchauspe G. Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection. Gastroenterology 2001; 120: 512-524
    • (2001) Gastroenterology , vol.120 , pp. 512-524
    • Bain, C.1    Fatmi, A.2    Zoulim, F.3    Zarski, J.P.4    Trepo, C.5    Inchauspe, G.6
  • 67
    • 12944293008 scopus 로고    scopus 로고
    • Hepatitis C virus core, NS3, NS5A, NS5B proteins induce apoptosis in mature dendritic cells
    • Siavoshian S, Abraham JD, Thumann C, Kieny MP, Schuster C. Hepatitis C virus core, NS3, NS5A, NS5B proteins induce apoptosis in mature dendritic cells. J Med Virol 2005; 75: 402-411
    • (2005) J Med Virol , vol.75 , pp. 402-411
    • Siavoshian, S.1    Abraham, J.D.2    Thumann, C.3    Kieny, M.P.4    Schuster, C.5
  • 68
    • 33947139667 scopus 로고    scopus 로고
    • Differential dysfunction in dendritic cell subsets during chronic HCV infection
    • Averill L, Lee WM, Karandikar NJ. Differential dysfunction in dendritic cell subsets during chronic HCV infection. Clin Immunol 2007; 123: 40-49
    • (2007) Clin Immunol , vol.123 , pp. 40-49
    • Averill, L.1    Lee, W.M.2    Karandikar, N.J.3
  • 70
    • 0037851770 scopus 로고    scopus 로고
    • Hepatitis C virus core and nonstructural protein 3 proteins induce pro-and anti-inflammatory cytokines and inhibit dendritic cell differentiation
    • Dolganiuc A, Kodys K, Kopasz A, Marshall C, Do T, Romics L Jr, Mandrekar P, Zapp M, Szabo G. Hepatitis C virus core and nonstructural protein 3 proteins induce pro-and anti-inflammatory cytokines and inhibit dendritic cell differentiation. J Immunol 2003; 170: 5615-5624
    • (2003) J Immunol , vol.170 , pp. 5615-5624
    • Dolganiuc, A.1    Kodys, K.2    Kopasz, A.3    Marshall, C.4    Do, T.5    Romics Jr, L.6    Mandrekar, P.7    Zapp, M.8    Szabo, G.9
  • 71
    • 3543001125 scopus 로고    scopus 로고
    • Isolation and functional analysis of circulating dendritic cells from hepatitis C virus (HCV) RNA-positive and HCV RNA-negative patients with chronic hepatitis C: Role of antiviral therapy
    • Tsubouchi E, Akbar SM, Murakami H, Horiike N, Onji M. Isolation and functional analysis of circulating dendritic cells from hepatitis C virus (HCV) RNA-positive and HCV RNA-negative patients with chronic hepatitis C: role of antiviral therapy. Clin Exp Immunol 2004; 137: 417-423
    • (2004) Clin Exp Immunol , vol.137 , pp. 417-423
    • Tsubouchi, E.1    Akbar, S.M.2    Murakami, H.3    Horiike, N.4    Onji, M.5
  • 73
    • 33750826035 scopus 로고    scopus 로고
    • Hepatitis C virus (HCV) core protein-induced, monocyte-mediated mechanisms of reduced IFN-alpha and plasmacytoid dendritic cell loss in chronic HCV infection
    • Dolganiuc A, Chang S, Kodys K, Mandrekar P, Bakis G, Cormier M, Szabo G. Hepatitis C virus (HCV) core protein-induced, monocyte-mediated mechanisms of reduced IFN-alpha and plasmacytoid dendritic cell loss in chronic HCV infection. J Immunol 2006; 177: 6758-6768
    • (2006) J Immunol , vol.177 , pp. 6758-6768
    • Dolganiuc, A.1    Chang, S.2    Kodys, K.3    Mandrekar, P.4    Bakis, G.5    Cormier, M.6    Szabo, G.7
  • 74
    • 55749109181 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells move down on the list of suspects: In search of the immune pathogenesis of chronic hepatitis C
    • Albert ML, Decalf J, Pol S. Plasmacytoid dendritic cells move down on the list of suspects: in search of the immune pathogenesis of chronic hepatitis C. J Hepatol 2008; 49: 1069-1078
    • (2008) J Hepatol , vol.49 , pp. 1069-1078
    • Albert, M.L.1    Decalf, J.2    Pol, S.3
  • 75
  • 77
    • 0031066827 scopus 로고    scopus 로고
    • Enhancement of cellular and humoral immune responses to hepatitis C virus core protein using DNA-based vaccines augmented with cytokine-expressing plasmids
    • Geissler M, Gesien A, Tokushige K, Wands JR. Enhancement of cellular and humoral immune responses to hepatitis C virus core protein using DNA-based vaccines augmented with cytokine-expressing plasmids. J Immunol 1997; 158: 1231-1237
    • (1997) J Immunol , vol.158 , pp. 1231-1237
    • Geissler, M.1    Gesien, A.2    Tokushige, K.3    Wands, J.R.4
  • 78
    • 0031573081 scopus 로고    scopus 로고
    • Inhibitory effects of chronic ethanol consumption on cellular immune responses to hepatitis C virus core protein are reversed by genetic immunizations augmented with cytokine-expressing plasmids
    • Geissler M, Gesien A, Wands JR. Inhibitory effects of chronic ethanol consumption on cellular immune responses to hepatitis C virus core protein are reversed by genetic immunizations augmented with cytokine-expressing plasmids. J Immunol 1997; 159: 5107-5113
    • (1997) J Immunol , vol.159 , pp. 5107-5113
    • Geissler, M.1    Gesien, A.2    Wands, J.R.3
  • 79
    • 0033854171 scopus 로고    scopus 로고
    • Ethanol inhibition: The humoral and cellular immune response to hepatitis C virus NS5 protein after genetic immunization
    • Encke J, Wands JR. Ethanol inhibition: the humoral and cellular immune response to hepatitis C virus NS5 protein after genetic immunization. Alcohol Clin Exp Res 2000; 24: 1063-1069
    • (2000) Alcohol Clin Exp Res , vol.24 , pp. 1063-1069
    • Encke, J.1    Wands, J.R.2
  • 80
    • 21644434561 scopus 로고    scopus 로고
    • Inhibition of antigen-presenting cell functions by alcohol: Implications for hepatitis C virus infection
    • Szabo G, Dolganiuc A, Mandrekar P, White B. Inhibition of antigen-presenting cell functions by alcohol: implications for hepatitis C virus infection. Alcohol 2004; 33: 241-249
    • (2004) Alcohol , vol.33 , pp. 241-249
    • Szabo, G.1    Dolganiuc, A.2    Mandrekar, P.3    White, B.4
  • 81
    • 0038308837 scopus 로고    scopus 로고
    • Additive inhibition of dendritic cell allostimulatory capacity by alcohol and hepatitis C is not restored by DC maturation and involves abnormal IL-10 and IL-2 induction
    • Dolganiuc A, Kodys K, Kopasz A, Marshall C, Mandrekar P, Szabo G. Additive inhibition of dendritic cell allostimulatory capacity by alcohol and hepatitis C is not restored by DC maturation and involves abnormal IL-10 and IL-2 induction. Alcohol Clin Exp Res 2003; 27: 1023-1031
    • (2003) Alcohol Clin Exp Res , vol.27 , pp. 1023-1031
    • Dolganiuc, A.1    Kodys, K.2    Kopasz, A.3    Marshall, C.4    Mandrekar, P.5    Szabo, G.6
  • 82
    • 4344593751 scopus 로고    scopus 로고
    • Inhibition of myeloid dendritic cell accessory cell function and induction of T cell anergy by alcohol correlates with decreased IL-12 production
    • Mandrekar P, Catalano D, Dolganiuc A, Kodys K, Szabo G. Inhibition of myeloid dendritic cell accessory cell function and induction of T cell anergy by alcohol correlates with decreased IL-12 production. J Immunol 2004; 173: 3398-3407
    • (2004) J Immunol , vol.173 , pp. 3398-3407
    • Mandrekar, P.1    Catalano, D.2    Dolganiuc, A.3    Kodys, K.4    Szabo, G.5
  • 83
    • 33847042376 scopus 로고    scopus 로고
    • Chronic ethanol consumption impairs cellular immune responses against HCV NS5 protein due to dendritic cell dysfunction
    • Aloman C, Gehring S, Wintermeyer P, Kuzushita N, Wands JR. Chronic ethanol consumption impairs cellular immune responses against HCV NS5 protein due to dendritic cell dysfunction. Gastroenterology 2007; 132: 698-708
    • (2007) Gastroenterology , vol.132 , pp. 698-708
    • Aloman, C.1    Gehring, S.2    Wintermeyer, P.3    Kuzushita, N.4    Wands, J.R.5
  • 89
    • 38749144367 scopus 로고    scopus 로고
    • A screening method for identifying disruptions in interferon signaling reveals HCV NS3/4a disrupts Stat-1 phosphorylation
    • Helbig KJ, Yip E, McCartney EM, Eyre NS, Beard MR. A screening method for identifying disruptions in interferon signaling reveals HCV NS3/4a disrupts Stat-1 phosphorylation. Antiviral Res 2008; 77: 169-176
    • (2008) Antiviral Res , vol.77 , pp. 169-176
    • Helbig, K.J.1    Yip, E.2    McCartney, E.M.3    Eyre, N.S.4    Beard, M.R.5
  • 92
    • 11144342298 scopus 로고    scopus 로고
    • Hepatitis C virus core protein down-regulates transcription of interferon-induced antiviral genes
    • de Lucas S, Bartolome J, Carreno V. Hepatitis C virus core protein down-regulates transcription of interferon-induced antiviral genes. J Infect Dis 2005; 191: 93-99
    • (2005) J Infect Dis , vol.191 , pp. 93-99
    • de Lucas, S.1    Bartolome, J.2    Carreno, V.3
  • 93
    • 3042740355 scopus 로고    scopus 로고
    • Expression of hepatitis C virus core protein inhibits interferon-induced nuclear import of STATs
    • Melen K, Fagerlund R, Nyqvist M, Keskinen P, Julkunen I. Expression of hepatitis C virus core protein inhibits interferon-induced nuclear import of STATs. J Med Virol 2004; 73: 536-547
    • (2004) J Med Virol , vol.73 , pp. 536-547
    • Melen, K.1    Fagerlund, R.2    Nyqvist, M.3    Keskinen, P.4    Julkunen, I.5
  • 94
    • 29744450126 scopus 로고    scopus 로고
    • Upregulation of protein phosphatase 2Ac by hepatitis C virus modulates NS3 helicase activity through inhibition of protein arginine methyltransferase 1
    • Duong FH, Christen V, Berke JM, Penna SH, Moradpour D, Heim MH. Upregulation of protein phosphatase 2Ac by hepatitis C virus modulates NS3 helicase activity through inhibition of protein arginine methyltransferase 1. J Virol 2005; 79: 15342-15350
    • (2005) J Virol , vol.79 , pp. 15342-15350
    • Duong, F.H.1    Christen, V.2    Berke, J.M.3    Penna, S.H.4    Moradpour, D.5    Heim, M.H.6
  • 96
    • 33645984234 scopus 로고    scopus 로고
    • S-Adenosylmethionine and betaine correct hepatitis C virus induced inhibition of interferon signaling in vitro
    • Duong FH, Christen V, Filipowicz M, Heim MH. S-Adenosylmethionine and betaine correct hepatitis C virus induced inhibition of interferon signaling in vitro. Hepatology 2006; 43: 796-806
    • (2006) Hepatology , vol.43 , pp. 796-806
    • Duong, F.H.1    Christen, V.2    Filipowicz, M.3    Heim, M.H.4
  • 97
    • 0141785229 scopus 로고    scopus 로고
    • Differential activation of interferon-inducible genes by hepatitis C virus core protein mediated by the interferon stimulated response element
    • Dansako H, Naganuma A, Nakamura T, Ikeda F, Nozaki A, Kato N. Differential activation of interferon-inducible genes by hepatitis C virus core protein mediated by the interferon stimulated response element. Virus Res 2003; 97: 17-30
    • (2003) Virus Res , vol.97 , pp. 17-30
    • Dansako, H.1    Naganuma, A.2    Nakamura, T.3    Ikeda, F.4    Nozaki, A.5    Kato, N.6
  • 100
    • 1842855210 scopus 로고    scopus 로고
    • Interferon-gamma inhibits interferon-alpha signalling in hepatic cells: Evidence for the involvement of STAT1 induction and hyperexpression of STAT1 in chronic hepatitis C
    • Radaeva S, Jaruga B, Kim WH, Heller T, Liang TJ, Gao B. Interferon-gamma inhibits interferon-alpha signalling in hepatic cells: evidence for the involvement of STAT1 induction and hyperexpression of STAT1 in chronic hepatitis C. Biochem J 2004; 379: 199-208
    • (2004) Biochem J , vol.379 , pp. 199-208
    • Radaeva, S.1    Jaruga, B.2    Kim, W.H.3    Heller, T.4    Liang, T.J.5    Gao, B.6
  • 101
    • 29244434123 scopus 로고    scopus 로고
    • Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells
    • Plumlee CR, Lazaro CA, Fausto N, Polyak SJ. Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells. Virol J 2005; 2: 89
    • (2005) Virol J , vol.2 , pp. 89
    • Plumlee, C.R.1    Lazaro, C.A.2    Fausto, N.3    Polyak, S.J.4
  • 102
    • 56749131192 scopus 로고    scopus 로고
    • Alcohol metabolism increases the replication of hepatitis C virus and attenuates the antiviral action of interferon
    • McCartney EM, Semendric L, Helbig KJ, Hinze S, Jones B, Weinman SA, Beard MR. Alcohol metabolism increases the replication of hepatitis C virus and attenuates the antiviral action of interferon. J Infect Dis 2008; 198: 1766-1775
    • (2008) J Infect Dis , vol.198 , pp. 1766-1775
    • McCartney, E.M.1    Semendric, L.2    Helbig, K.J.3    Hinze, S.4    Jones, B.5    Weinman, S.A.6    Beard, M.R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.