CD8+ T cell cross-priming via transfer of proteasome substrates

Science

Volumn 304, Issue 5675, 2004, Pages 1318-1321

  Norbury, Christopher C ^a,b   Basta, Sameh ^a,c   Donohue, Keri B ^b   Tscharke, David C ^a,d   Princiotta, Michael F ^a   Berglund, Peter ^a   Gibbs, James ^a   Bennink, Jack R ^a   Yewdell, Jonathan W ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF KONSTANZ   (Germany)

^d QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENS; PROTEINS; TUMORS; VACCINES;

CROSS-PRIMING; RATIONAL DESIGN;

CELLS;

CD8 ANTIGEN; CHAPERONE; LIGAND; PEPTIDE; PROTEASOME; TUMOR ANTIGEN; VACCINE; VIRUS ANTIGEN;

ANTIGEN; IMMUNE SYSTEM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; T LYMPHOCYTE ACTIVATION;

ACETYLCYSTEINE; ANIMALS; ANTIGEN PRESENTATION; ANTIGENS; ANTIGENS, VIRAL; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; CROSS-PRIMING; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; ENDOPLASMIC RETICULUM; HUMANS; IMMUNIZATION; INFLUENZA A VIRUS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOLECULAR CHAPERONES; MULTIENZYME COMPLEXES; OVALBUMIN; PEPTIDE FRAGMENTS; PROTEASOME ENDOPEPTIDASE COMPLEX; RECOMBINANT FUSION PROTEINS; VACCINES; VACCINIA VIRUS;

ANIMALIA;

EID: 2542574206     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1096378     Document Type: Article

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