The effect of ethanol-induced CYP2E1 on proteasome activity: The role of 4-hydroxynonenal

Experimental and Molecular Pathology

Volumn 78, Issue 2, 2005, Pages 109-115

  Bardag Gorce, Fawzia ^a   Li, Jun ^a   French, Barbara A ^a   French, Samuel W ^a  

^a HARBOR UCLA MEDICAL CENTER   (United States)

Author keywords

4 Hydroxynonenal; CYP2E1 induction; Ethanol feeding; Proteasome

Indexed keywords

4 HYDROXYNONENAL; ADENOSINE TRIPHOSPHATASE; ALCOHOL; CHYMOTRYPSIN; CYTOCHROME P450 2E1; ENZYME ANTIBODY; PROTEASOME; PROTEIN RPT4; TRYPSIN; UNCLASSIFIED DRUG;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME ISOLATION; ENZYME SUBUNIT; LIVER; MALE; NONHUMAN; RAT; STAINING; STATISTICAL SIGNIFICANCE; WESTERN BLOTTING;

EID: 13844298275     PISSN: 00144800     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexmp.2004.10.005     Document Type: Article

References (31)

1. E. Albano, P. Clot, M. Morimoto, A. Tomasi, M. Ingelman-Sundberg, and S.W. French Role of cytochrome P4502E1-dependent formation of hydroxyethyl free radical in the development of liver damage in rats intragastrically fed with ethanol Hepatology 23 1996 155 163
2. E. Albano, S.W. French, and M. Ingelman-Sundberg Hydroxyethyl radicals in ethanol hepatotoxicity Front. Biosci. 4 1999 533 540
3. Y. Ando, N. Nyhlin, O. Suhr, G. Holmgren, K. Uchida, M. El Sahly, T. Yamashita, H. Terasaki, M. Nakamura, M. Uchino, and M. Ando Oxidative stress is found in amyloid deposits in systemic amyloidosis Biochem. Biophys. Res. Commun. 232 1997 497 502
4. F. Bardag-Gorce, Q.X. Yuan, J. Li, B.A. French, C. Fang, M. Ingelman-Sundberg, and S.W. French The effect of ethanol-induced cytochrome P450 2E1 on the inhibition of proteasome activity by alcohol Biochem. Biophys. Res. Commun. 279 2000 23 29
5. F. Bardag-Gorce, B.A. French, J. Li, N.E. Riley, Q.X. Yuan, V. Valinluck, P. Fu, M. Ingelman-Sundberg, S. Yoon, and S.W. French The importance of cycling of blood alcohol levels in the pathogenesis of experimental alcoholic liver disease in rats Gastroenterology 123 1 2002 325 335
6. F. Bardag-Gorce, J. Li, B.A. French, and S.W. French Ethanol withdrawal induced CYP2E1 degradation in vivo, blocked by proteasomal inhibitor PS-341 Free Radical Biol. Med. 32 2002 17 21
7. M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 72 1976 248 254
8. A.L. Bulteau, K.C. Lundberg, K.M. Humphries, H.A. Sadek, P.A. Szweda, B. Friguet, and L.I. Szweda Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion J. Biol. Chem. 276 2001 30057 30063
9. J.A. Cohn, L. Tsai, B. Friguet, and L.I. Szweda Chemical characterization of a protein-4-hydroxy-2-nonenal cross-link: immunochemical detection in mitochondria exposed to oxidative stress Arch. Biochem. Biophys. 328 1996 158 164
10. T.M. Donohue Jr., R.K. Zetterman, Z.Q. Zhang-Gouillon, and S.W. French Peptidase activities of the multicatalytic protease in rat liver after voluntary and intragastric ethanol administration Hepatology 28 1998 486 491
11. H. Esterbauer, R.J. Schaur, and H. Zollner Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes Free Radical Biol. Med. 11 1991 81 128
12. V. Fataccioli, E. Andraud, M. Gentil, S. French, and H. Rouach Effects of chronic ethanol administration on rat liver proteasome activities: relationship with oxidative stress Hepatology 29 1999 14 20
13. S.W. French, T.J. Ihrig, and R.J. Morin Lipid composition of RBC ghosts, liver mitochondria and microsomes of ethanol-fed rats Q. J. Stud. Alcohol 31 1970 801 809
14. S.W. French, K. Wong, L. Jui, E. Albano, A.L. Hagbjork, and M. Ingelman-Sundberg Effect of ethanol on cytochrome P450 2E1 (CYP2E1), lipid peroxidation, and serum protein adduct formation in relation to liver pathology pathogenesis Exp. Mol. Pathol. 58 1993 61 75
15. S.W. French, M. Morimoto, R.C. Reitz, D. Koop, B. Klopfenstein, K. Estes, P. Clot, M. Ingelman-Sundberg, and E. Albano Lipid peroxidation, CYP2E1 and arachidonic acid metabolism in alcoholic liver disease in rats J. Nutr. 127 1997 907S 911S
16. B. Friguet, and L.I. Szweda Inhibition of the multicatalytic proteinase (proteasome) by 4-hydroxy-2-nonenal cross-linked protein FEBS Lett. 405 1997 21 25
17. Z. Gouillon, D. Lucas, J. Li, A.L. Hagbjork, B.A. French, P. Fu, C. Fang, M. Ingelman-Sundberg, T.M. Donohue Jr., and S.W. French Inhibition of ethanol-induced liver disease in the intragastric feeding rat model by chlormethiazole Proc. Soc. Exp. Biol. Med. 224 2000 302 308
18. R. Hartmann-Petersen, K. Tanaka, and K.B. Hendil Quaternary structure of the ATPase complex of human 26 S proteasomes determined by chemical cross-linking Arch. Biochem. Biophys. 386 1 2001 89 94
19. R. Hough, G. Pratt, and M. Rechsteiner Purification of two high molecular weight proteases from rabbit reticulocyte lysate J. Biol. Chem. 262 1987 8303 8313
20. A. Kohler, P. Cascio, D.S. Leggett, K.M. Woo, A.L. Goldberg, and D. Finley The axial channel of the proteasome core particle is gated by the Rpt2 ATPase and controls both substrate entry and product release Mol. Cell 7 2001 1143 1152
21. C.J. Li, A.A. Nanji, A.N. Siakotos, and R.C. Lin Acetaldehyde-modified and 4-hydroxynonenal-modified proteins in the livers of rats with alcoholic liver disease Hepatology 26 1997 650 657
22. J. Li, V. Nguyen, B.A. French, A.F. Parlow, G.L. Su, P. Fu, Q.X. Yuan, and S.W. French Mechanism of the alcohol cyclic pattern: role of the hypothalamic-pituitary-thyroid axis Am. J. Physiol.: Gastrointest. Liver Physiol. 279 2000 G118 G125
23. M. Morimoto, A.L. Hagbjork, Y.J. Wan, P.C. Fu, P. Clot, E. Albano, M. Ingelman-Sundberg, and S.W. French Modulation of experimental alcohol-induced liver disease by cytochrome P450 2E1 inhibitors Hepatology 21 1995 1610 1617
24. M. Morimoto, R.C. Reitz, R.J. Morin, K. Nguyen, M. Ingelman-Sundberg, and S.W. French CYP-2E1 inhibitors partially ameliorate the changes in hepatic fatty acid composition induced in rats by chronic administration of ethanol and a high fat diet J. Nutr. 125 1995 2953 2964
25. E. Mottaran, S.F. Stewart, R. Rolla, D. Vay, V. Cipriani, M. Moretti, M. Vidali, M. Sartori, C. Rigamonti, C.P. Day, and E. Albano Lipid peroxidation contributes to immune reactions associated with alcoholic liver disease Free Radical Biol. Med. 32 1 2002 38 45
26. P. Navasumrit, T.H. Ward, N.J. Dodd, and P.J. O'Connor Ethanol-induced free radicals and hepatic DNA strand breaks are prevented in vivo by antioxidants: effects of acute and chronic ethanol exposure Carcinogenesis 21 1 2000 93 99
27. K. Okada, C. Wangpoengtrakul, T. Osawa, S. Toyokuni, K. Tanaka, and K. Uchida 4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules J. Biol. Chem. 274 1999 23787 23793
28. D.R. Petersen, and J.A. Doorn Reactions of 4-hydroxynonenal with proteins and cellular targets Free Radical Biol. Med. 37 2004 937 945
29. S.J. Russell, F. Gonzalez, L. Joshua-Tor, and S.A. Johnston Selective chemical inactivation of AAA proteins reveals distinct functions of proteasomal ATPases Chem. Biol. 8 10 2001 941 950
30. A. Sevanian, K. Nordenbrand, E. Kim, L. Ernster, and P. Hochstein Microsomal lipid peroxidation: the role of NADPH-cytochrome P450 reductase and cytochrome P450 Free Radical Biol. Med. 8 1990 145 152
31. A. Yoritaka, N. Hattori, K. Uchida, M. Tanaka, E.R. Stadtman, and Y. Mizuno Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease Proc. Natl. Acad. Sci. U. S. A. 93 1996 2696 2701