Hepatitis C virus non-structural protein NS3 interacts with LMP7, a component of the immunoproteasome, and affects its proteasome activity

Biochemical Journal

Volumn 384, Issue 2, 2004, Pages 401-409

  Khu, Yee Ling ^a   Tan, Yee Joo ^a   Lim, Seng Gee ^a,b   Hong, Wanjin ^a   Goh, Phuay Yee ^a  

^a INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^b NATIONAL UNIVERSITY HOSPITAL   (Singapore)

Author keywords

Hepatitis C virus (HCV); Immunoproteasome; Low molecular mass protein 7 (LMP7); Non structural protein NS3; Proteasome

Indexed keywords

ANTIGENS; ENZYME KINETICS; IMMUNOLOGY; PROTEINS; RNA; VIRUSES;

CO-IMMUNOPRECIPITATION ANALYSIS; POLYPROTEINS; RNA REPLICATION; RNA TRANSLATION;

DISEASES;

BINDING PROTEIN; LOW MOLECULAR MASS PROTEIN 7; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NON STRUCTURAL PROTEIN NS3; PROTEASOME; PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VIRUS ENZYME; VIRUS PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME REGULATION; HEPATITIS C; HEPATITIS C VIRUS; HOST; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IMMUNOSURVEILLANCE; IN VITRO STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; REPLICON; RNA REPLICATION; RNA TRANSLATION; TWO HYBRID SYSTEM; VIRUS VIRULENCE; YEAST;

ANIMALS; CELL LINE; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; COS CELLS; GENE LIBRARY; HELA CELLS; HUMANS; IMMUNOPRECIPITATION; MULTIENZYME COMPLEXES; PEPTIDE HYDROLASES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN INTERACTION MAPPING; SPLEEN; TWO-HYBRID SYSTEM TECHNIQUES; VIRAL NONSTRUCTURAL PROTEINS; YEASTS;

ANIMALIA; HEPATITIS C VIRUS; RNA VIRUSES;

EID: 10644229240     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20040858     Document Type: Article

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