Inactivation of hCDC4 can cause chromosomal instability

Nature

Volumn 428, Issue 6978, 2004, Pages 77-81

  Rajagopalan, Harith ^a   Jallepalli, Prasad V ^a,b   Rago, Carlo ^a   Velculescu, Victor E ^a   Kinzler, Kenneth W ^a   Vogelstein, Bert ^a,c   Lengauer, Christoph ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DATA REDUCTION; GENETIC ENGINEERING; MUTAGENESIS; PROTEINS; STABILITY; TUMORS;

GENETIC INACTIVATION; PRECURSORS;

CHROMOSOMES;

CELL CYCLE PROTEIN; CELL CYCLE PROTEIN 4; UNCLASSIFIED DRUG; CYCLIN E; F BOX PROTEIN; FBXW7 PROTEIN, HUMAN; MESSENGER RNA; UBIQUITIN PROTEIN LIGASE;

BIOLOGY;

ANEUPLOIDY; ARTICLE; CANCER CELL; CHROMOSOME ABERRATION; COLORECTAL CANCER; GENE DISRUPTION; GENE EXPRESSION; GENE INACTIVATION; HUMAN; HUMAN CELL; KARYOTYPE; METAPHASE; MICRONUCLEUS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; CHEMICAL STRUCTURE; CHEMISTRY; COLORECTAL TUMOR; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DELETION; GENETICS; GENOMIC INSTABILITY; METABOLISM; MUTATION; PROTEIN CONFORMATION; TUMOR CELL LINE;

ANEUPLOIDY; CELL CYCLE PROTEINS; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; CYCLIN E; F-BOX PROTEINS; GENE DELETION; GENOMIC INSTABILITY; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MODELS, MOLECULAR; MUTATION; PROTEIN CONFORMATION; RNA, MESSENGER; UBIQUITIN-PROTEIN LIGASES;

EID: 1542377277     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature02313     Document Type: Article

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