Synthesis of chaetomellic anhydride A, A potent inhibitor of ras protein farnesyltransferase

Heterocycles

Volumn 77, Issue 1, 2009, Pages 179-186

  Yoshimitsu, Takehiko ^a   Arano, Yoshimasa ^b   Kaji, Tomohiro ^a   Ino, Tatsunori ^a   Nagaoka, Hiroto ^b   Tanaka, Tetsuaki ^a  

^a OSAKA UNIVERSITY   (Japan)

^b MEIJI PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Anticancer; Carbonylation; Maleic Anhydride; Palladium Catalyzed; Total Synthesis

Indexed keywords

EID: 65549127592     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/COM-08-S(F)16     Document Type: Article

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44. 2Na), however, was used as the formic salt throughout this study because of ease of availability.
45. +): 180.0786, found: 180.0789.
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50. 3) δ 3.57 (s, 3H), 2.25 (t, 2H, J=8 Hz), 2.09 (s, 3H), 1.88 (s, 3H), 1.37-1.16 (m, 24H), 0.88 (t, 3H, J=7 Hz).