A novel metal-chelating inhibitor of protein farnesyltransferase

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 9, 2003, Pages 1523-1526

  Hamasaki, Akiyuki ^a   Naka, Hayato ^b   Tamanoi, Fuyuhiko ^c   Umezawa, Kazuo ^b   Otsuka, Masami ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b KEIO UNIVERSITY   (Japan)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (8 CHLORO 5,6 DIHYDRO 11H BENZO[5,6]CYCLOHEPTA[1,2 B]PYRIDIN 11 YLIDENE) 1 (4 PYRIDYLACETYL)PIPERIDINE; 4 (NAPHTHALEN 1 YL)PYRIDINE; BIPYRIDINE; ETHYLENEDIAMINE; MANUMYCIN; MERCAPTAMINE; METAL CHELATE; NAPHTHYL GROUP; NEW DRUG; PROTEIN FARNESYLTRANSFERASE; PROTEIN FARNESYLTRANSFERASE INHIBITOR; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG; ZINC;

ANIMAL CELL; ARTICLE; CELL GROWTH; CELL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; GROWTH INHIBITION; IC 50; KIDNEY CELL; NONHUMAN; RAT;

EID: 12444283656     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00183-5     Document Type: Article

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