-
1
-
-
33745593721
-
Generation of neuronal variability and complexity
-
Muotri AR, Gage FH, Generation of neuronal variability and complexity, Nature 441(7097):1087-1093, 2006.
-
(2006)
Nature
, vol.441
, Issue.7097
, pp. 1087-1093
-
-
Muotri, A.R.1
Gage, F.H.2
-
2
-
-
1942467937
-
Somatic mutation: A cause of sporadic neurogdegenerative diseases?
-
Pamphlett R, Somatic mutation: a cause of sporadic neurogdegenerative diseases?, Med Hypotheses 62:679-682, 2004.
-
(2004)
Med Hypotheses
, vol.62
, pp. 679-682
-
-
Pamphlett, R.1
-
3
-
-
0027171266
-
Oxidants, antioxidants, and the degenerative diseases of aging
-
Ames B, Shigenaga M, Oxidants, antioxidants, and the degenerative diseases of aging, Proc Natl Acad Sci 90:7915-7922, 1993.
-
(1993)
Proc Natl Acad Sci
, vol.90
, pp. 7915-7922
-
-
Ames, B.1
Shigenaga, M.2
-
4
-
-
0033565934
-
Internal hazards: Baseline DNA damage by endogenous products of normal metabolism
-
Burcham P, Internal hazards: Baseline DNA damage by endogenous products of normal metabolism, Mutat Res-Gen Tox En 443(1-2):11-36, 1999.
-
(1999)
Mutat Res-Gen Tox En
, vol.443
, Issue.1-2
, pp. 11-36
-
-
Burcham, P.1
-
5
-
-
0032932583
-
Rearranging views on neurogenesis: Neuronal death in the absence of DNA end-joining proteins
-
Chun J, Schatz DG, Rearranging views on neurogenesis: Neuronal death in the absence of DNA end-joining proteins, Neuron 22:7-10, 1999.
-
(1999)
Neuron
, vol.22
, pp. 7-10
-
-
Chun, J.1
Schatz, D.G.2
-
6
-
-
0034672057
-
Xrcc2 is required for genetic stability, embryonic neurogenesis, and viability in mice
-
Deans B, Griffin CS, Maconochie M, Thacker J, Xrcc2 is required for genetic stability, embryonic neurogenesis, and viability in mice, The EMBO Journal 19(24):6675-6685, 2000.
-
(2000)
The EMBO Journal
, vol.19
, Issue.24
, pp. 6675-6685
-
-
Deans, B.1
Griffin, C.S.2
Maconochie, M.3
Thacker, J.4
-
7
-
-
38449096702
-
The necessary junk: New functions for transposable elements
-
Muotri AR, Marchetto M, Coufal NG, Gage FH, The necessary junk: new functions for transposable elements, Hum Mol Genet 16(2):159-167, 2007.
-
(2007)
Hum Mol Genet
, vol.16
, Issue.2
, pp. 159-167
-
-
Muotri, A.R.1
Marchetto, M.2
Coufal, N.G.3
Gage, F.H.4
-
8
-
-
20544466648
-
Somatic mosaicism in neuronal precursor cells mediated by l1 retrotransposition
-
Muotri AR, Chu V, Marchetto M, DengW, Moran JV, Gage FH, Somatic mosaicism in neuronal precursor cells mediated by l1 retrotransposition, Nature 435:903-910, 2005.
-
(2005)
Nature
, vol.435
, pp. 903-910
-
-
Muotri, A.R.1
Chu, V.2
Marchetto, M.3
Deng, W.4
Moran, J.V.5
Gage, F.H.6
-
10
-
-
0029863114
-
Widespread programmed cell death in proliferative and postmitotic regions of the fetal cerebral cortex
-
Blaschke AJ, Staley K, Chun J, Widespread programmed cell death in proliferative and postmitotic regions of the fetal cerebral cortex, Development 122:1165-1174, 1996.
-
(1996)
Development
, vol.122
, pp. 1165-1174
-
-
Blaschke, A.J.1
Staley, K.2
Chun, J.3
-
11
-
-
0035818519
-
Chromosomal variation in neurons of the developing and adult mammalian nervous system
-
Rehen SK, McConnell MJ, Kaushal D, Kingsbury MA, Yang AH, Chun J, Chromosomal variation in neurons of the developing and adult mammalian nervous system, Proc Natl Acad Sci 98(23):13361-13366, 2001.
-
(2001)
Proc Natl Acad Sci
, vol.98
, Issue.23
, pp. 13361-13366
-
-
Rehen, S.K.1
McConnell, M.J.2
Kaushal, D.3
Kingsbury, M.A.4
Yang, A.H.5
Chun, J.6
-
12
-
-
0037078982
-
Control, exploitation and tolerance of intracellular noise
-
Rao CV, Wolf DM, Arkin AP, Control, exploitation and tolerance of intracellular noise, Nature 420(6912):231-237, 2002.
-
(2002)
Nature
, vol.420
, Issue.6912
, pp. 231-237
-
-
Rao, C.V.1
Wolf, D.M.2
Arkin, A.P.3
-
13
-
-
65349156814
-
A discrete approach to top-down modeling of biochemical networks
-
Elsevier Academic Press, pp
-
Laubenbacher R, Mendes P, A discrete approach to top-down modeling of biochemical networks, in Computational Systems Biology, Elsevier Academic Press, pp. 229-247, 2006.
-
(2006)
Computational Systems Biology
, pp. 229-247
-
-
Laubenbacher, R.1
Mendes, P.2
-
14
-
-
0035957409
-
Computing an organism
-
Segel LA, Computing an organism, Proc Natl Acad Sci 98(7):3639-3640, 2001.
-
(2001)
Proc Natl Acad Sci
, vol.98
, Issue.7
, pp. 3639-3640
-
-
Segel, L.A.1
-
15
-
-
0037805572
-
-
Maini PK, Making sense of complex phenomena in biology, in 'In Silico' Simulation of Biological Processes, 247, Novartis Symposium, pp. 53-59, 2002.
-
Maini PK, Making sense of complex phenomena in biology, in 'In Silico' Simulation of Biological Processes, Vol. 247, Novartis Symposium, pp. 53-59, 2002.
-
-
-
-
16
-
-
0015231849
-
Parameter sensitivity as a criterion for evaluating and comparing the performance of biochemical systems
-
Savageau MA, Parameter sensitivity as a criterion for evaluating and comparing the performance of biochemical systems, Nature 229:542-544, 1971.
-
(1971)
Nature
, vol.229
, pp. 542-544
-
-
Savageau, M.A.1
-
17
-
-
0033518234
-
From molecular to modular cell biology
-
Hartwell LH, Hopfield JJ, Leibler S, Murray AW, From molecular to modular cell biology, Nature 402:c48-c52, 1999.
-
(1999)
Nature
, vol.402
-
-
Hartwell, L.H.1
Hopfield, J.J.2
Leibler, S.3
Murray, A.W.4
-
18
-
-
7644238181
-
Biological robustness
-
Kitano H, Biological robustness, Nat Rev Gen 5:826-837, 2004.
-
(2004)
Nat Rev Gen
, vol.5
, pp. 826-837
-
-
Kitano, H.1
-
19
-
-
0037108607
-
Design and constraints of the drosophila segment polarity module: Robust spatial patterning emerges from intertwined cell state switches
-
von Dassow G, Odell GM, Design and constraints of the drosophila segment polarity module: Robust spatial patterning emerges from intertwined cell state switches, J Exp Zool 294:179-215, 2002.
-
(2002)
J Exp Zool
, vol.294
, pp. 179-215
-
-
von Dassow, G.1
Odell, G.M.2
-
20
-
-
0034644270
-
The segment polarity network is a robust developmental module
-
von Dassow G, Meir MEM, Odell GM, The segment polarity network is a robust developmental module, Nature 406:188-192, 2000.
-
(2000)
Nature
, vol.406
, pp. 188-192
-
-
von Dassow, G.1
Meir, M.E.M.2
Odell, G.M.3
-
21
-
-
0037136555
-
Robustness of the BMP morphogen gradient in drosophila embryonic patterning
-
Eldar A, Dorfman R, Weiss D, Ashe H, Shilo B-Z, Barkai N, Robustness of the BMP morphogen gradient in drosophila embryonic patterning, Nature 419(6904):304-308, 2002.
-
(2002)
Nature
, vol.419
, Issue.6904
, pp. 304-308
-
-
Eldar, A.1
Dorfman, R.2
Weiss, D.3
Ashe, H.4
Shilo, B.-Z.5
Barkai, N.6
-
22
-
-
12344296412
-
Mathematical modeling of planar cell polarity to understand domineering nonautonomy
-
Amonlirdviman K, Khare NA, Tree DRP, Chen W-S, Axelrod JD, Tomlin CJ, Mathematical modeling of planar cell polarity to understand domineering nonautonomy, Science 307(5708):423-426, 2005.
-
(2005)
Science
, vol.307
, Issue.5708
, pp. 423-426
-
-
Amonlirdviman, K.1
Khare, N.A.2
Tree, D.R.P.3
Chen, W.-S.4
Axelrod, J.D.5
Tomlin, C.J.6
-
23
-
-
0036301511
-
Robustness as a measure of plausibility in models of biochemical networks
-
Morohashi M, Winn A, Borisuk M, Bolouri H, Doyle J, Kitano H, Robustness as a measure of plausibility in models of biochemical networks, J Theor Biol 216:19-30, 2002.
-
(2002)
J Theor Biol
, vol.216
, pp. 19-30
-
-
Morohashi, M.1
Winn, A.2
Borisuk, M.3
Bolouri, H.4
Doyle, J.5
Kitano, H.6
-
24
-
-
19544379881
-
Stochasticity in gene expression: From theories to phenotypes
-
Kaern M, Elston TC, Blake WJ, Collins JJ, Stochasticity in gene expression: From theories to phenotypes, Nat Rev Genet 6(6):451-464, 2005.
-
(2005)
Nat Rev Genet
, vol.6
, Issue.6
, pp. 451-464
-
-
Kaern, M.1
Elston, T.C.2
Blake, W.J.3
Collins, J.J.4
-
25
-
-
3142523466
-
Noise, delays, robustness, canalization and all that
-
Kerszberg M, Noise, delays, robustness, canalization and all that, Curr Opin Gen Dev 14:440-445, 2004.
-
(2004)
Curr Opin Gen Dev
, vol.14
, pp. 440-445
-
-
Kerszberg, M.1
-
26
-
-
34249084013
-
Neuronal subtype specification in the cerebral cortex
-
Molyneaux BJ, Arlotta P, Menezes JRL, Macklis JD, Neuronal subtype specification in the cerebral cortex, Nat Rev Neurosci 8(6):427-437, 2007.
-
(2007)
Nat Rev Neurosci
, vol.8
, Issue.6
, pp. 427-437
-
-
Molyneaux, B.J.1
Arlotta, P.2
Menezes, J.R.L.3
Macklis, J.D.4
-
28
-
-
24344510750
-
The cell biology of neurogenesis
-
Gotz M, Huttner WB, The cell biology of neurogenesis, Nat Rev Mol Cell Bio 6(10):777-788, 2005.
-
(2005)
Nat Rev Mol Cell Bio
, vol.6
, Issue.10
, pp. 777-788
-
-
Gotz, M.1
Huttner, W.B.2
-
29
-
-
0035320035
-
A unified hypothesis on the lineage of neural stem cells
-
Alvarez-Buylla A, Garcia-Verdugo J, Tramontin A, A unified hypothesis on the lineage of neural stem cells, Nat Rev Neurosci 4:287-293, 2001.
-
(2001)
Nat Rev Neurosci
, vol.4
, pp. 287-293
-
-
Alvarez-Buylla, A.1
Garcia-Verdugo, J.2
Tramontin, A.3
-
30
-
-
0037092422
-
Dividing precursor cells of the embryonic cortical ventricular zone have morphological and molecular characteristics of radial glia
-
Noctor SC, Flint AC,Weissman TA,WongWS, Clinton BK, Kriegstein AR, Dividing precursor cells of the embryonic cortical ventricular zone have morphological and molecular characteristics of radial glia, J Neurosci 22(8):3161-3173, 2002.
-
(2002)
J Neurosci
, vol.22
, Issue.8
, pp. 3161-3173
-
-
Noctor, S.C.1
Flint, A.C.2
Weissman, T.A.3
Wong, W.S.4
Clinton, B.K.5
Kriegstein, A.R.6
-
31
-
-
0346868807
-
Neurogenesis in the adult brain: New strategies for central nervous system diseases
-
Lie DC, Song H, Colamarino SA, Ming G-L, Gage FH, Neurogenesis in the adult brain: New strategies for central nervous system diseases, Annu Rev Pharmacol 44(1):399-421, 2004.
-
(2004)
Annu Rev Pharmacol
, vol.44
, Issue.1
, pp. 399-421
-
-
Lie, D.C.1
Song, H.2
Colamarino, S.A.3
Ming, G.-L.4
Gage, F.H.5
-
32
-
-
32544445546
-
Molecular and morphological heterogeneity of neural precursors in the mouse neocortical proliferative zones
-
Gal JS, Morozov YM, Ayoub AE, Chatterjee M, Rakic P, Haydar TF, Molecular and morphological heterogeneity of neural precursors in the mouse neocortical proliferative zones, J Neurosci 26(3):1045-1056, 2006.
-
(2006)
J Neurosci
, vol.26
, Issue.3
, pp. 1045-1056
-
-
Gal, J.S.1
Morozov, Y.M.2
Ayoub, A.E.3
Chatterjee, M.4
Rakic, P.5
Haydar, T.F.6
-
33
-
-
0025952778
-
Cell cycle dependence of laminar determination in developing neocortex
-
McConnell SK, Kaznowski CE, Cell cycle dependence of laminar determination in developing neocortex, Science 254:282-285, 1991.
-
(1991)
Science
, vol.254
, pp. 282-285
-
-
McConnell, S.K.1
Kaznowski, C.E.2
-
34
-
-
0029026103
-
The cell cycle of the pseudostratified ventricular epithelium of the embryonic murine cerebral wall
-
Takahashi T, Nowakowski RS, Caviness VS Jr, The cell cycle of the pseudostratified ventricular epithelium of the embryonic murine cerebral wall, J Neurosci 15(9):6046-6057, 1995.
-
(1995)
J Neurosci
, vol.15
, Issue.9
, pp. 6046-6057
-
-
Takahashi, T.1
Nowakowski, R.S.2
Caviness Jr, V.S.3
-
35
-
-
0029789473
-
The leaving or Q fraction of the murine cerebral proliferative epithelium: A general model of neocortical neuronogenesis
-
Takahashi T, Nowakowski RS, Caviness VS Jr, The leaving or Q fraction of the murine cerebral proliferative epithelium: A general model of neocortical neuronogenesis, J Neurosci 16(19):6183-6196, 1996.
-
(1996)
J Neurosci
, vol.16
, Issue.19
, pp. 6183-6196
-
-
Takahashi, T.1
Nowakowski, R.S.2
Caviness Jr, V.S.3
-
36
-
-
0031030251
-
Apoptosis and its relation to the cell cycle in the developing cerebral cortex
-
Thomaidou D, Mione MC, Cavanagh JFR, Parnavelas JG, Apoptosis and its relation to the cell cycle in the developing cerebral cortex, J Neurosci 17(3):1075-1085, 1997.
-
(1997)
J Neurosci
, vol.17
, Issue.3
, pp. 1075-1085
-
-
Thomaidou, D.1
Mione, M.C.2
Cavanagh, J.F.R.3
Parnavelas, J.G.4
-
37
-
-
0037106215
-
Size distribution of retrovirally marked lineages matches prediction from population measurements of cell cycle behavior
-
Cai L, Hayes NL, Takahashi T, Caviness VS Jr, Nowakowski RS, Size distribution of retrovirally marked lineages matches prediction from population measurements of cell cycle behavior, J Neurosci Res 69:731-744, 2002.
-
(2002)
J Neurosci Res
, vol.69
, pp. 731-744
-
-
Cai, L.1
Hayes, N.L.2
Takahashi, T.3
Caviness Jr, V.S.4
Nowakowski, R.S.5
-
38
-
-
3042815947
-
The role of cell death during neocortical neurogenesis and synaptogenesis: Implications from a computational model for the rat and mouse
-
Gohlke J, Griffith W, Faustman E, The role of cell death during neocortical neurogenesis and synaptogenesis: Implications from a computational model for the rat and mouse, Dev Brain Res 151:43-54, 2004.
-
(2004)
Dev Brain Res
, vol.151
, pp. 43-54
-
-
Gohlke, J.1
Griffith, W.2
Faustman, E.3
-
39
-
-
65349145748
-
Mathematical modeling of extensive neural progenitor cell (NPC) death during cerebral cortical development
-
Submitted
-
McConnell MJ, MacMillan H, Chun J, Mathematical modeling of extensive neural progenitor cell (NPC) death during cerebral cortical development, Cerebral Cortex, Submitted.
-
Cerebral Cortex
-
-
McConnell, M.J.1
MacMillan, H.2
Chun, J.3
-
40
-
-
22244492586
-
Selective lengthening of the cell cycle in the neurogenic subpopulation of neural progenitor cells during mouse brain development
-
Calegari F, Haubensak W, Haffner C, Huttner WB, Selective lengthening of the cell cycle in the neurogenic subpopulation of neural progenitor cells during mouse brain development, J Neurosci 25(28):6533-6538, 2005.
-
(2005)
J Neurosci
, vol.25
, Issue.28
, pp. 6533-6538
-
-
Calegari, F.1
Haubensak, W.2
Haffner, C.3
Huttner, W.B.4
-
41
-
-
0033966875
-
BTG gene expression in the p53-dependent and -independent cellular response to DNA damage
-
Cortes U, Moyret-Lalle C, Fallette N, Duriez C, El Ghissassi F, Barnas C, Morel AP, Hainaut P, Magaud J-P, Puisieux A, BTG gene expression in the p53-dependent and -independent cellular response to DNA damage, Mol Carcinogen 27:57-64, 2000.
-
(2000)
Mol Carcinogen
, vol.27
, pp. 57-64
-
-
Cortes, U.1
Moyret-Lalle, C.2
Fallette, N.3
Duriez, C.4
El Ghissassi, F.5
Barnas, C.6
Morel, A.P.7
Hainaut, P.8
Magaud, J.-P.9
Puisieux, A.10
-
42
-
-
18344377030
-
The p53 pathway: Positive and negative feedback loops
-
Harris SL, Levine AJ, The p53 pathway: Positive and negative feedback loops, Oncogene 24:2899-2980, 2005.
-
(2005)
Oncogene
, vol.24
, pp. 2899-2980
-
-
Harris, S.L.1
Levine, A.J.2
-
43
-
-
0034676455
-
Surfing the p53 network
-
Vogelstein B, Lane D, Levine AJ, Surfing the p53 network, Nature 408:307-310, 2000.
-
(2000)
Nature
, vol.408
, pp. 307-310
-
-
Vogelstein, B.1
Lane, D.2
Levine, A.J.3
-
44
-
-
0344392982
-
Chromosome segregation defects contribute to aneuploidy in normal neural progenitor cells
-
Yang AH, Kaushal D, Rehen SK, Kriedt K, Kingsbury MA, McConnell MJ, Chun J, Chromosome segregation defects contribute to aneuploidy in normal neural progenitor cells, J Neurosci Res 23(32):10454-10462, 2003.
-
(2003)
J Neurosci Res
, vol.23
, Issue.32
, pp. 10454-10462
-
-
Yang, A.H.1
Kaushal, D.2
Rehen, S.K.3
Kriedt, K.4
Kingsbury, M.A.5
McConnell, M.J.6
Chun, J.7
-
45
-
-
4644245822
-
Failed clearance of aneuploid embryonic neural progenitor cells leads to excess aneuploidy in the ATM-deficient but not the Trp53-deficient adult cerebral cortex
-
McConnell MJ, Kaushal D, Yang AH, Kingsbury MA, Rehen SK, Treuner K, Helton R, Annas EG, Chun J, Barlow C, Failed clearance of aneuploid embryonic neural progenitor cells leads to excess aneuploidy in the ATM-deficient but not the Trp53-deficient adult cerebral cortex, J Neurosci 24(37):8090-8096, 2004.
-
(2004)
J Neurosci
, vol.24
, Issue.37
, pp. 8090-8096
-
-
McConnell, M.J.1
Kaushal, D.2
Yang, A.H.3
Kingsbury, M.A.4
Rehen, S.K.5
Treuner, K.6
Helton, R.7
Annas, E.G.8
Chun, J.9
Barlow, C.10
-
46
-
-
0038045576
-
Alteration of gene expression by chromosome loss in the postnatal mouse brain
-
Kaushal D, Yang AH, Rehen SK, Kriedt K, Kingsbury MA, McConnell MJ, Chun J, Alteration of gene expression by chromosome loss in the postnatal mouse brain, J Neurosci 23(13):5599-5606, 2003.
-
(2003)
J Neurosci
, vol.23
, Issue.13
, pp. 5599-5606
-
-
Kaushal, D.1
Yang, A.H.2
Rehen, S.K.3
Kriedt, K.4
Kingsbury, M.A.5
McConnell, M.J.6
Chun, J.7
-
47
-
-
0032784908
-
Interspersed repeats and other momentos of transposable elements in mammalian genomes
-
Smit AF, Interspersed repeats and other momentos of transposable elements in mammalian genomes, Curr Opin Gen Dev 9:657-663, 1999.
-
(1999)
Curr Opin Gen Dev
, vol.9
, pp. 657-663
-
-
Smit, A.F.1
-
48
-
-
33645068168
-
The human line-1 retrotransposon creates DNA double-strand breaks
-
Gasior S, Wakeman T, Xu B, Deininger P, The human line-1 retrotransposon creates DNA double-strand breaks, J Mol Biol 357:1383-1393, 2006.
-
(2006)
J Mol Biol
, vol.357
, pp. 1383-1393
-
-
Gasior, S.1
Wakeman, T.2
Xu, B.3
Deininger, P.4
-
49
-
-
0035144498
-
Human l1 retrotransposition: Cis preference versus trans complementation
-
Wei W, Gilbert N, Ooi SL, Lawler J, Ostertag E, Kazazian H, Boeke J, Moran J, Human l1 retrotransposition: cis preference versus trans complementation, Mol Cell Biol 21(4):1429-1439, 2001.
-
(2001)
Mol Cell Biol
, vol.21
, Issue.4
, pp. 1429-1439
-
-
Wei, W.1
Gilbert, N.2
Ooi, S.L.3
Lawler, J.4
Ostertag, E.5
Kazazian, H.6
Boeke, J.7
Moran, J.8
-
50
-
-
0026058318
-
Cell death during development of the nervous system
-
Oppenheim R, Cell death during development of the nervous system, Annu Rev Neurosci 14:453-501, 1991.
-
(1991)
Annu Rev Neurosci
, vol.14
, pp. 453-501
-
-
Oppenheim, R.1
-
51
-
-
65349145150
-
Personal communication
-
unpublished data
-
Muotri AR, Personal communication, unpublished data, 2008.
-
(2008)
-
-
Muotri, A.R.1
-
52
-
-
17844408690
-
A cell-centered approach to developmental biology
-
Merks RM, Glazier JA, A cell-centered approach to developmental biology, Physica A 352(1):113-130, 2005.
-
(2005)
Physica A
, vol.352
, Issue.1
, pp. 113-130
-
-
Merks, R.M.1
Glazier, J.A.2
-
53
-
-
33846300352
-
Morpheus unbound: Reimagining the morphogen gradient
-
Lander AD, Morpheus unbound: Reimagining the morphogen gradient, Cell 128:245-256, 2007.
-
(2007)
Cell
, vol.128
, pp. 245-256
-
-
Lander, A.D.1
-
54
-
-
84889852463
-
Neurogenesis in the central nervous system
-
Unsicker K, Krieglstein K eds, Wile-VCH, pp
-
Dubreuil V, Farkas L, Calegari F, Kosodo Y, Huttner WB, Neurogenesis in the central nervous system, in Unsicker K, Krieglstein K (eds.), Cell Signaling and Growth Factors in Development, Vol. 1, Wile-VCH, pp. 229-286, 2006.
-
(2006)
Cell Signaling and Growth Factors in Development
, vol.1
, pp. 229-286
-
-
Dubreuil, V.1
Farkas, L.2
Calegari, F.3
Kosodo, Y.4
Huttner, W.B.5
-
55
-
-
0037047611
-
MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network
-
Bhalla US, Ram PT, Iyengar R, MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network, Science 297(5583):1018-1023, 2002.
-
(2002)
Science
, vol.297
, Issue.5583
, pp. 1018-1023
-
-
Bhalla, U.S.1
Ram, P.T.2
Iyengar, R.3
-
56
-
-
0036467578
-
Anchorage-dependent erk signaling - mechanisms and consequences
-
Howe AK, Aplin AE, Juliano RL, Anchorage-dependent erk signaling - mechanisms and consequences, Curr Opin Gen Dev 12:30-35, 2002.
-
(2002)
Curr Opin Gen Dev
, vol.12
, pp. 30-35
-
-
Howe, A.K.1
Aplin, A.E.2
Juliano, R.L.3
-
57
-
-
33644524741
-
Cell-signalling dynamics in time and space
-
Kholodenko BN, Cell-signalling dynamics in time and space, Nat Rev Mol Cell Biol 7(3):165-176, 2006.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, Issue.3
, pp. 165-176
-
-
Kholodenko, B.N.1
-
58
-
-
33748699122
-
-
Chignola R, Dai P Pra, Morato LM, Siri P, Proliferation and death in a binary environment: A stochastic model of cellular ecosystems, B Math Biol 68:1661-1680, 2006.
-
Chignola R, Dai P Pra, Morato LM, Siri P, Proliferation and death in a binary environment: A stochastic model of cellular ecosystems, B Math Biol 68:1661-1680, 2006.
-
-
-
-
59
-
-
0037376417
-
Apoptosis, proliferation, differentiation: In search of the order
-
Blagosklonny MV, Apoptosis, proliferation, differentiation: In search of the order, Semin Cancer Biol 13:97-105, 2003.
-
(2003)
Semin Cancer Biol
, vol.13
, pp. 97-105
-
-
Blagosklonny, M.V.1
-
60
-
-
0036022410
-
Mathematical models of the balance between apoptosis and proliferation
-
Hardy K, Stark J, Mathematical models of the balance between apoptosis and proliferation, Apoptosis 7:373-381, 2002.
-
(2002)
Apoptosis
, vol.7
, pp. 373-381
-
-
Hardy, K.1
Stark, J.2
-
61
-
-
85015066476
-
DNA damage and repair
-
Friedberg E, DNA damage and repair, Nature 421:436-440, 2003.
-
(2003)
Nature
, vol.421
, pp. 436-440
-
-
Friedberg, E.1
-
62
-
-
0037365789
-
Safeguar ding genome integrity
-
ATM and related protein kinases
-
Shiloh Y, ATM and related protein kinases: Safeguar ding genome integrity, Nat Rev Cancer 397:155-168, 2003.
-
(2003)
Nat Rev Cancer
, vol.397
, pp. 155-168
-
-
Shiloh, Y.1
-
63
-
-
0036948433
-
Toward maintaining the genome: DNA damage and replication checkpoints
-
Nyberg K, Michelson R, Putnam C, Weinert T, Toward maintaining the genome: DNA damage and replication checkpoints, Annu Rev Genet 36(1):617-656, 2002.
-
(2002)
Annu Rev Genet
, vol.36
, Issue.1
, pp. 617-656
-
-
Nyberg, K.1
Michelson, R.2
Putnam, C.3
Weinert, T.4
-
64
-
-
3042814563
-
Radiation and the cell cycle revisited
-
Wilson G, Radiation and the cell cycle revisited, Cancer Metast Rev 23:209-225, 2004.
-
(2004)
Cancer Metast Rev
, vol.23
, pp. 209-225
-
-
Wilson, G.1
-
65
-
-
23944446057
-
Replication and transcription: Shaping the landscape of the genome
-
Chakalova L, Debrand E, Mitchell J, Osborne C, Fraser P, Replication and transcription: Shaping the landscape of the genome, Nat Rev Gen 6(9):669-677, 2005.
-
(2005)
Nat Rev Gen
, vol.6
, Issue.9
, pp. 669-677
-
-
Chakalova, L.1
Debrand, E.2
Mitchell, J.3
Osborne, C.4
Fraser, P.5
-
66
-
-
35748961986
-
p53 enters the microRNA world
-
Hermeking H, p53 enters the microRNA world, Cancer Cell 12(5):414-418, 2007.
-
(2007)
Cancer Cell
, vol.12
, Issue.5
, pp. 414-418
-
-
Hermeking, H.1
-
67
-
-
33745451921
-
Oscillations and variability in the p53 system
-
Geva-Zatorsky N, Rosenfeld N, Itzkovitz S, Milo R, Sigal A, Dekel E, Yarnitzky T, Liron Y, Polak P, Lahav G, Alon U, Oscillations and variability in the p53 system, Mol Sys Bio 2:E1-E13, 2006.
-
(2006)
Mol Sys Bio
, vol.2
-
-
Geva-Zatorsky, N.1
Rosenfeld, N.2
Itzkovitz, S.3
Milo, R.4
Sigal, A.5
Dekel, E.6
Yarnitzky, T.7
Liron, Y.8
Polak, P.9
Lahav, G.10
Alon, U.11
-
68
-
-
42949171936
-
Recurrent initiation: A mechanism for triggering p53 pulses in response to DNA damage
-
Batchelor E, Mock C, Bhan I, Loewer A, Lahav G, Recurrent initiation: A mechanism for triggering p53 pulses in response to DNA damage, Mol Cell 30(3):277-289, 2008.
-
(2008)
Mol Cell
, vol.30
, Issue.3
, pp. 277-289
-
-
Batchelor, E.1
Mock, C.2
Bhan, I.3
Loewer, A.4
Lahav, G.5
-
69
-
-
4444349425
-
A model for restriction point control of the mammalian cell cycle
-
Novak B, Tyson JJ, A model for restriction point control of the mammalian cell cycle, J Theor Biol 230(4):563-579, 2004.
-
(2004)
J Theor Biol
, vol.230
, Issue.4
, pp. 563-579
-
-
Novak, B.1
Tyson, J.J.2
-
70
-
-
0033925842
-
A mathematical model of caspase function in apoptosis
-
Fussenegger M, Bailey JE, Varner J, A mathematical model of caspase function in apoptosis, Nat Biotechnol 18:768-774, 2000.
-
(2000)
Nat Biotechnol
, vol.18
, pp. 768-774
-
-
Fussenegger, M.1
Bailey, J.E.2
Varner, J.3
-
71
-
-
0348143168
-
An inhibition of cyclin-dependent kinases that lengthens, but does not arrest, neuroepithelial cell cycle induces premature neurogenesis
-
Calegari F, Huttner WB, An inhibition of cyclin-dependent kinases that lengthens, but does not arrest, neuroepithelial cell cycle induces premature neurogenesis, J Cell Sci 116(24):4947-4955, 2003.
-
(2003)
J Cell Sci
, vol.116
, Issue.24
, pp. 4947-4955
-
-
Calegari, F.1
Huttner, W.B.2
-
72
-
-
0035252797
-
Cell cycle and cell fate in the nervous system
-
Ohnuma S, Philpott A, Harris WA, Cell cycle and cell fate in the nervous system, Curr Opin Neurobiol 11:66-73, 2001.
-
(2001)
Curr Opin Neurobiol
, vol.11
, pp. 66-73
-
-
Ohnuma, S.1
Philpott, A.2
Harris, W.A.3
-
73
-
-
0141918786
-
Neurogenesis and the cell cycle
-
Ohnuma S, HarrisWA, Neurogenesis and the cell cycle, Neuron 40(2):199-208, 2003.
-
(2003)
Neuron
, vol.40
, Issue.2
, pp. 199-208
-
-
Ohnuma, S.1
HarrisWA2
-
74
-
-
33847032960
-
The mammalian epigenome
-
Bernstein B, Meissner A, Lander ES, The mammalian epigenome, Cell 128:669-681, 2007.
-
(2007)
Cell
, vol.128
, pp. 669-681
-
-
Bernstein, B.1
Meissner, A.2
Lander, E.S.3
-
75
-
-
0037313618
-
Coordinated regulation of life and death by RB
-
Chau B, Wang JY, Coordinated regulation of life and death by RB, Nat Rev Cancer 3:130-138, 2003.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 130-138
-
-
Chau, B.1
Wang, J.Y.2
-
76
-
-
11244276992
-
The E2F family: Specific functions and overlapping interests
-
Attwooll C, Denchi EL, Helin K, The E2F family: Specific functions and overlapping interests, The EMBO J 23:4709-4716, 2004.
-
(2004)
The EMBO J
, vol.23
, pp. 4709-4716
-
-
Attwooll, C.1
Denchi, E.L.2
Helin, K.3
-
78
-
-
35948943082
-
Aneuploidy: Instigator and inhibitor of tumorigenesis
-
Weaver B, Cleveland D, Aneuploidy: Instigator and inhibitor of tumorigenesis, Cancer Res 67:10103-10105, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 10103-10105
-
-
Weaver, B.1
Cleveland, D.2
-
79
-
-
0037376655
-
Dynamics of regulatory and signaling pathways in the cells
-
Tyson JJ, Chen KC, Novak B, Sniffers, buzzers, toggles, and blinkers: Dynamics of regulatory and signaling pathways in the cells, Curr Opin Cell Biol 15:221-231, 2003.
-
(2003)
Curr Opin Cell Biol
, vol.15
, pp. 221-231
-
-
Tyson, J.J.1
Chen, K.C.2
Novak, B.3
Sniffers4
buzzers5
toggles6
blinkers7
-
80
-
-
0035478585
-
Macromolecular crowding: Obvious but underappreciated
-
Ellis RJ, Macromolecular crowding: Obvious but underappreciated, Trends Biochem Sci 26:597-604, 2001.
-
(2001)
Trends Biochem Sci
, vol.26
, pp. 597-604
-
-
Ellis, R.J.1
-
81
-
-
0031853923
-
Development of fractal kinetic theory for enzyme-catalysed reactions and implications for the design of biochemical pathways
-
Savageau MA, Development of fractal kinetic theory for enzyme-catalysed reactions and implications for the design of biochemical pathways, Biosystems 47(1-2):9-36, 1998.
-
(1998)
Biosystems
, vol.47
, Issue.1-2
, pp. 9-36
-
-
Savageau, M.A.1
-
82
-
-
2442543316
-
Reaction kinetics in intracellular environments with macromolecular crowding: Simulations and rate laws
-
Schnell S, Turner TE, Reaction kinetics in intracellular environments with macromolecular crowding: Simulations and rate laws, Prog Biophy Mol Biol 28(3):235-260, 2004.
-
(2004)
Prog Biophy Mol Biol
, vol.28
, Issue.3
, pp. 235-260
-
-
Schnell, S.1
Turner, T.E.2
-
84
-
-
0031029852
-
Stochastic mechansims in gene expression
-
McAdams HH, Arkin A, Stochastic mechansims in gene expression, Proc Natl Acad Sci 94:814-819, 1997.
-
(1997)
Proc Natl Acad Sci
, vol.94
, pp. 814-819
-
-
McAdams, H.H.1
Arkin, A.2
-
85
-
-
0036207347
-
Modeling and simulation of genetic regulatory systems: A literature review
-
DeJong H, Modeling and simulation of genetic regulatory systems: A literature review, J Comput Biol 96(1):67-103, 2002.
-
(2002)
J Comput Biol
, vol.96
, Issue.1
, pp. 67-103
-
-
DeJong, H.1
-
87
-
-
0035193294
-
Stochasticity in transcriptional regulation: Origins, consequences, and mathematical representations
-
Kepler T, Elston T, Stochasticity in transcriptional regulation: Origins, consequences, and mathematical representations, Biophys J 81:3116-3136, 2001.
-
(2001)
Biophys J
, vol.81
, pp. 3116-3136
-
-
Kepler, T.1
Elston, T.2
-
88
-
-
3142577523
-
Stochastic approaches for modelling in vivo reactions
-
Turner TE, Schnell S, Burrage K, Stochastic approaches for modelling in vivo reactions, Comput Biol Chem 28:165-178, 2004.
-
(2004)
Comput Biol Chem
, vol.28
, pp. 165-178
-
-
Turner, T.E.1
Schnell, S.2
Burrage, K.3
-
89
-
-
20544474049
-
Toward predictive models of mammalian cells
-
Ma'ayan A, Blitzer RD, Iyengar R, Toward predictive models of mammalian cells, Annu Rev Bioph Biom 34:319-349, 2005.
-
(2005)
Annu Rev Bioph Biom
, vol.34
, pp. 319-349
-
-
Ma'ayan, A.1
Blitzer, R.D.2
Iyengar, R.3
-
90
-
-
0037119587
-
Stochastic gene expression in single cell
-
Elowitz MB, Levine AJ, Siggia ED, Swain PS, Stochastic gene expression in single cell, Science 297:1183-1186, 2002.
-
(2002)
Science
, vol.297
, pp. 1183-1186
-
-
Elowitz, M.B.1
Levine, A.J.2
Siggia, E.D.3
Swain, P.S.4
-
91
-
-
0036790975
-
Intrinsic and extrinsic contributions to stochasticity in gene expression
-
Swain PS, Elowitz MB, Siggia ED, Intrinsic and extrinsic contributions to stochasticity in gene expression, Proc Natl Acad Sci 99(22):12795-12800, 2002.
-
(2002)
Proc Natl Acad Sci
, vol.99
, Issue.22
, pp. 12795-12800
-
-
Swain, P.S.1
Elowitz, M.B.2
Siggia, E.D.3
-
92
-
-
33750533388
-
Physicochemical modelling of cell signalling pathways
-
Aldridge BB, Burke JM, Lauffenburger DA, Sorger P, Physicochemical modelling of cell signalling pathways, Nat Cell Biol 8(11):1195- 1203, 2006.
-
(2006)
Nat Cell Biol
, vol.8
, Issue.11
, pp. 1195-1203
-
-
Aldridge, B.B.1
Burke, J.M.2
Lauffenburger, D.A.3
Sorger, P.4
-
93
-
-
0001389945
-
Enxyme induction as an all-or-none phenomenon
-
Novick A, Weiner M, Enxyme induction as an all-or-none phenomenon, Proc Natl Acad Sci 43:553-566, 1957.
-
(1957)
Proc Natl Acad Sci
, vol.43
, pp. 553-566
-
-
Novick, A.1
Weiner, M.2
-
94
-
-
33747128581
-
Single cell data analysis and ensemble modeling
-
Elucidating the digital control mechanism for DNA damage repair with the p53-Mdm2 system
-
Ogunnaike BA, Elucidating the digital control mechanism for DNA damage repair with the p53-Mdm2 system: Single cell data analysis and ensemble modeling, J Roy Soc Interface 3(6):175-184, 2006.
-
(2006)
J Roy Soc Interface
, vol.3
, Issue.6
, pp. 175-184
-
-
Ogunnaike, B.A.1
-
95
-
-
0038075338
-
Decision making by p53: Life, death, and cancer
-
Oren R, Decision making by p53: Life, death, and cancer, Cell Death Diff 10:431-442, 2003.
-
(2003)
Cell Death Diff
, vol.10
, pp. 431-442
-
-
Oren, R.1
-
96
-
-
17844364758
-
Exploring modularity with dynamical models gene networks
-
The University of Chicago Press, pp
-
von Dassow G, Meir E, Exploring modularity with dynamical models gene networks, in Modularity in Development and Evolution, The University of Chicago Press, pp. 244-288, 2004.
-
(2004)
Modularity in Development and Evolution
, pp. 244-288
-
-
von Dassow, G.1
Meir, E.2
-
97
-
-
33845410054
-
Dynamic modelling and analysis of biochemical networks: Mechanism-based models and model-based experiments
-
van Riel NAW, Dynamic modelling and analysis of biochemical networks: Mechanism-based models and model-based experiments, Brief Bioinform 7(4):364-374, 2006.
-
(2006)
Brief Bioinform
, vol.7
, Issue.4
, pp. 364-374
-
-
van Riel, N.A.W.1
-
98
-
-
21244472631
-
Emergence and its place in nature: A case study of biochemical networks
-
Boogerd FC, Bruggeman FJ, Richardson RC, Stephan A,Westerhoff HV, Emergence and its place in nature: A case study of biochemical networks, Synthese 145(1):131-164, 2005.
-
(2005)
Synthese
, vol.145
, Issue.1
, pp. 131-164
-
-
Boogerd, F.C.1
Bruggeman, F.J.2
Richardson, R.C.3
Stephan, A.4
Westerhoff, H.V.5
-
99
-
-
19344375343
-
The meaning of systems biology
-
Kirschner M, The meaning of systems biology, Cell 121(4):503-504, 2005.
-
(2005)
Cell
, vol.121
, Issue.4
, pp. 503-504
-
-
Kirschner, M.1
-
101
-
-
0003445619
-
-
George Braziller, Inc
-
von Bertalanffy L, General Systems Theory: Foundations, Development, Applications, George Braziller, Inc., 1968.
-
(1968)
General Systems Theory: Foundations, Development, Applications
-
-
von Bertalanffy, L.1
-
102
-
-
65349135265
-
-
PhD thesis, Florida State University, Tallahassee, FL
-
Webster C, Sparse grid stochastic collocation techniques for the numerical solution of partial differential equations with random input data, PhD thesis, Florida State University, Tallahassee, FL, 2007.
-
(2007)
Sparse grid stochastic collocation techniques for the numerical solution of partial differential equations with random input data
-
-
Webster, C.1
-
104
-
-
0001048297
-
Quadrature and interpolation formulas for tensor products of certain classes of functions
-
Smolyak SA, Quadrature and interpolation formulas for tensor products of certain classes of functions, Sov Math 4:240-243, 1963.
-
(1963)
Sov Math
, vol.4
, pp. 240-243
-
-
Smolyak, S.A.1
-
105
-
-
0037249229
-
The wiener-askey polynomial chaos for stochastic differential equations
-
Xiu D, Karniadakis GE, The wiener-askey polynomial chaos for stochastic differential equations, SIAM J Sci Comput 24(2):619-644, 2002.
-
(2002)
SIAM J Sci Comput
, vol.24
, Issue.2
, pp. 619-644
-
-
Xiu, D.1
Karniadakis, G.E.2
-
106
-
-
65349092712
-
Reduced order modeling of some nonlinear stochastic partial differential equations
-
to appear
-
Burkardt J, Webster C, Reduced order modeling of some nonlinear stochastic partial differential equations, Int J Num Anal Mod, to appear.
-
Int J Num Anal Mod
-
-
Burkardt, J.1
Webster, C.2
-
108
-
-
0003418645
-
A restriction point for control of normal animal cell proliferation
-
Pardeee AB, A restriction point for control of normal animal cell proliferation, Proc Natl Acad Sci 71(4):1286-1290, 1974.
-
(1974)
Proc Natl Acad Sci
, vol.71
, Issue.4
, pp. 1286-1290
-
-
Pardeee, A.B.1
-
109
-
-
0032533225
-
Glycogen synthase kinase-3b regulates cyclin d1 proteolysis and subcellular localization
-
Diehl JA, Cheng M, Roussel MF, Sherr CJ, Glycogen synthase kinase-3b regulates cyclin d1 proteolysis and subcellular localization, Gene Dev 12(22):3499-3511, 1998.
-
(1998)
Gene Dev
, vol.12
, Issue.22
, pp. 3499-3511
-
-
Diehl, J.A.1
Cheng, M.2
Roussel, M.F.3
Sherr, C.J.4
-
110
-
-
0029033861
-
The Retinoblastoma protein and cell cycle control
-
Weinberg R, The Retinoblastoma protein and cell cycle control, Cell 81:323-330, 1995.
-
(1995)
Cell
, vol.81
, pp. 323-330
-
-
Weinberg, R.1
-
111
-
-
0035848819
-
The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis
-
Falck J, Mailand N, Syljuasen RG, Bartek J, Lukas J, The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis, Nature 410:842-847, 2001.
-
(2001)
Nature
, vol.410
, pp. 842-847
-
-
Falck, J.1
Mailand, N.2
Syljuasen, R.G.3
Bartek, J.4
Lukas, J.5
-
112
-
-
0035020051
-
Integration of the pRb and p53 cell cycle control pathways
-
Stewart C, Soria A, Hamel P, Integration of the pRb and p53 cell cycle control pathways, J Neuro-Oncol 51:183-204, 2001.
-
(2001)
J Neuro-Oncol
, vol.51
, pp. 183-204
-
-
Stewart, C.1
Soria, A.2
Hamel, P.3
-
113
-
-
10044259944
-
Coordination of repair, checkpoint, and cell death responses to DNA damage
-
J. Y. J. Wang, Cho SK, Coordination of repair, checkpoint, and cell death responses to DNA damage, Adv Protein Chem 69:101-135, 2004.
-
(2004)
Adv Protein Chem
, vol.69
, pp. 101-135
-
-
Wang, J.Y.J.1
Cho, S.K.2
-
114
-
-
2642549143
-
Dynamics of centromere and kinetichore proteins: Implications for checkpoint signaling and silencing
-
Shah J, Botvinick E, Bonday Z, Furnari F, Berns M, Cleveland DW, Dynamics of centromere and kinetichore proteins: Implications for checkpoint signaling and silencing, Curr Biol 14:942-952, 2004.
-
(2004)
Curr Biol
, vol.14
, pp. 942-952
-
-
Shah, J.1
Botvinick, E.2
Bonday, Z.3
Furnari, F.4
Berns, M.5
Cleveland, D.W.6
|