Nickel-catalyzed biaryl coupling of heteroarenes and aryl halides/triflates

Organic Letters

Volumn 11, Issue 8, 2009, Pages 1733-1736

  Canivet, Jérôme ^a   Yamaguchi, Junichiro ^a   Ban, Ikuya ^a   Itami, Kenichiro ^a  

^a NAGOYA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FEBUXOSTAT; HALOGENATED HYDROCARBON; MESYLIC ACID DERIVATIVE; NICKEL; THIAZOLE DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; COMBINATORIAL CHEMISTRY; SYNTHESIS;

COMBINATORIAL CHEMISTRY TECHNIQUES; HYDROCARBONS, HALOGENATED; MESYLATES; MOLECULAR STRUCTURE; NICKEL; THIAZOLES;

EID: 65249162972     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol9001587     Document Type: Article

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107. Febuxostat has already been approved for use in Europe, and the FDA's Arthritis Advisory Committee has recently recommended approval for use in the U.S. If approved, febuxostat will be the first new treatment for the management of gout-associated hyperuricemia in more than 40 years.
108. 2 ($610 for 2 g).