Glucose transport regulation by p210 Bcr-Abl in a chronic myeloid leukaemia model

British Journal of Haematology

Volumn 112, Issue 1, 2001, Pages 212-215

  Bentley, J ^a,d   Walker, I ^a   McIntosh, E ^a   Whetton, A D ^b   Owen Lynch, P J ^b,c   Baldwin, S A ^a  

^a LANCASTER UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF LEEDS   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Bcr Abl; CML; Glucose transport; Multipotent stem cells; PI3 kinase

Indexed keywords

BCR ABL PROTEIN; GLUCOSE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; CHRONIC MYELOID LEUKEMIA; ENZYME ACTIVATION; GLUCOSE TRANSPORT; HEMATOPOIETIC STEM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BIOLOGICAL TRANSPORT; CELL DEATH; CELL LINE; DEOXYGLUCOSE; FUSION PROTEINS, BCR-ABL; HEMATOPOIETIC STEM CELLS; HUMANS; LEUKEMIA, MYELOID, CHRONIC;

EID: 0035137924     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2001.02428.x     Document Type: Article

References (9)

1. Apoptosis in hematopoiesis and leukemogenesis
2. Signaling mechanisms that regulate glucose transport
3. Implicating the bcr/abl gene in the pathogenesis of Philadelphia chromosome-positive human leukemia
4. Initiation of deregulated growth of multipotent progenitor cells by Bcr-Abl in vitro
5. Autocrine production and action of IL-3 and granulocyte colony-stimulating factor in chronic myeloid leukaemia
6. Apoptosis is regulated by the rate of glucose transport in an interleukin-3 dependent cell line
7. Tyrosine kinase-activity and transformation potency of Bcr-Abl oncogene products
8. Interleukin-3 and p210 BCR/ABL activate both unique and overlapping pathways of signal transduction in a factor-dependent myeloid cell line
9. p210 Bcr-Abl expression in a primitive multipotent haematopoietic cell line models the development of chronic myeloid leukaemia