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Volumn 62, Issue , 2008, Pages 694-707

Defensins and cathelicidins as natural peptide antibiotics;Defensyny i katelicydyny jako naturalne antybiotyki peptydowe

Author keywords

Antimicrobial peptides; Cathelicidins; Cationic peptides; Chemotaxis; Defensins; Innate immunity; Leukocytes; Natural antibiotics; and defensins

Indexed keywords

ANTIINFECTIVE AGENT; CATHELICIDIN; DEFENSIN;

EID: 63149151694     PISSN: 00325449     EISSN: 17322693     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (28)

References (111)
  • 5
    • 34548150567 scopus 로고    scopus 로고
    • Mechanisms of endotoxin neutralization by synthetic cationic compounds
    • Andra J., Gutsmann T., Garidel P., Brandenburg K.: Mechanisms of endotoxin neutralization by synthetic cationic compounds. J. Endotoxin. Res., 2006; 12: 261-277
    • (2006) J. Endotoxin. Res. , vol.12 , pp. 261-277
    • Andra, J.1    Gutsmann, T.2    Garidel, P.3    Brandenburg, K.4
  • 6
    • 0001216086 scopus 로고    scopus 로고
    • Epithelial antimicrobial peptides in host defense against infection
    • Bals R.: Epithelial antimicrobial peptides in host defense against infection. Respir. Res., 2001; 1: 141
    • (2001) Respir. Res. , vol.1 , pp. 141
    • Bals, R.1
  • 7
    • 1042269503 scopus 로고    scopus 로고
    • Innate immunity in the lung: How epithelial cells fight against respiratory pathogens
    • Bals R., Hiemstra P.S.: Innate immunity in the lung: how epithelial cells fight against respiratory pathogens. Eur. Respir. J., 2004; 23: 327-333
    • (2004) Eur. Respir. J. , vol.23 , pp. 327-333
    • Bals, R.1    Hiemstra, P.S.2
  • 8
    • 0035188391 scopus 로고    scopus 로고
    • Structure determination of human and murine β-defensins reveals structural conservation in the absence of significant sequence similarity
    • Bauer F., Schweimer K., Kluver E., Conejo-Garcia J.R., Forssmann W.G., Rosch P., Adermann K., Sticht H.: Structure determination of human and murine β-defensins reveals structural conservation in the absence of significant sequence similarity. Protein Sci., 2001; 10: 2470-2479
    • (2001) Protein Sci. , vol.10 , pp. 2470-2479
    • Bauer, F.1    Schweimer, K.2    Kluver, E.3    Conejo-Garcia, J.R.4    Forssmann, W.G.5    Rosch, P.6    Adermann, K.7    Sticht, H.8
  • 9
    • 7444239122 scopus 로고    scopus 로고
    • The Paneth cell and innate immune response
    • Bevins C.L.: The Paneth cell and innate immune response. Curr. Opin. Gastroenterol., 2004; 20: 572-580
    • (2004) Curr. Opin. Gastroenterol. , vol.20 , pp. 572-580
    • Bevins, C.L.1
  • 10
    • 0032732928 scopus 로고    scopus 로고
    • Defensins and innate host defence of the gastrointestinal tract
    • Bevins C.L., Martin-Porter E., Ganz T.: Defensins and innate host defence of the gastrointestinal tract. Gut, 1999; 45: 911-915
    • (1999) Gut , vol.45 , pp. 911-915
    • Bevins, C.L.1    Martin-Porter, E.2    Ganz, T.3
  • 11
    • 13844308074 scopus 로고    scopus 로고
    • Defensins-non-antibiotic use for vaccine development
    • Biragyn A.: Defensins-non-antibiotic use for vaccine development. Curr. Protein Pept. Sci., 2005; 6: 53-60
    • (2005) Curr. Protein Pept. Sci. , vol.6 , pp. 53-60
    • Biragyn, A.1
  • 13
    • 0042830450 scopus 로고    scopus 로고
    • Antibacterial peptides: Basic facts and emerging concepts
    • Boman H.G.: Antibacterial peptides: basic facts and emerging concepts. J. Intern. Med., 2003; 254: 197-215
    • (2003) J. Intern. Med. , vol.254 , pp. 197-215
    • Boman, H.G.1
  • 16
    • 13844315653 scopus 로고    scopus 로고
    • A re-evaluation of the role of host defence peptides in mammalian immunity
    • Bowdish D.M., Davidson D.J., Hancock R.E.: A re-evaluation of the role of host defence peptides in mammalian immunity. Curr. Protein Pept. Sci., 2005; 6: 35-51
    • (2005) Curr. Protein Pept. Sci. , vol.6 , pp. 35-51
    • Bowdish, D.M.1    Davidson, D.J.2    Hancock, R.E.3
  • 17
    • 0029347190 scopus 로고
    • Plant defensins: Novel antimicrobial peptides as components of the host defense system
    • Broekaert W.F., Terras F.R., Cammue B.P., Osborn R.W.: Plant defensins: novel antimicrobial peptides as components of the host defense system. Plant Physiol., 1995; 108: 1353-1358
    • (1995) Plant Physiol. , vol.108 , pp. 1353-1358
    • Broekaert, W.F.1    Terras, F.R.2    Cammue, B.P.3    Osborn, R.W.4
  • 18
    • 14544282377 scopus 로고    scopus 로고
    • Antimicrobial peptides: Pore formers or metabolic inhibitors in bacteria?
    • Brogden K.A.: Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? Nat. Rev. Microbiol., 2005; 3: 238-250
    • (2005) Nat. Rev. Microbiol. , vol.3 , pp. 238-250
    • Brogden, K.A.1
  • 19
    • 1642545489 scopus 로고    scopus 로고
    • Anti-microbial peptides: From intervertebres to vertebras
    • Bulet P., Stocklin R., Menin L.: Anti-microbial peptides: from intervertebres to vertebras. Immunol. Rev., 2004; 198: 169-184
    • (2004) Immunol. Rev. , vol.198 , pp. 169-184
    • Bulet, P.1    Stocklin, R.2    Menin, L.3
  • 20
    • 10344240423 scopus 로고    scopus 로고
    • Structure activity relationships in defensin dimmers. A novel link between β-defensin tertiary structure and antimicrobial activity
    • Campopiano D.J., Clarke D.J., Polfer N.C., Barran P.E., Langley R.J., Govan J.R., Maxwell A., Dorin J.R.: Structure activity relationships in defensin dimers. A novel link between β-defensin tertiary structure and antimicrobial activity. J. Biol. Chem., 2004; 279: 48671-48679
    • (2004) J. Biol. Chem. , vol.279 , pp. 48671-48679
    • Campopiano, D.J.1    Clarke, D.J.2    Polfer, N.C.3    Barran, P.E.4    Langley, R.J.5    Govan, J.R.6    Maxwell, A.7    Dorin, J.R.8
  • 22
    • 33749324492 scopus 로고    scopus 로고
    • High level expression of epithelial β-defensins (hBD-1, 2, and 3) in papillomavirus induced lesions
    • Chong K.T., Xiang L., Wang X., Jun E.L., Xi L., Schweinfurth J.M.: High level expression of epithelial β-defensins (hBD-1, 2, and 3) in papillomavirus induced lesions. Vir. J., 2006; 3: 75
    • (2006) Vir. J. , vol.3 , pp. 75
    • Chong, K.T.1    Xiang, L.2    Wang, X.3    Jun, E.L.4    Xi, L.5    Schweinfurth, J.M.6
  • 26
    • 0036214967 scopus 로고    scopus 로고
    • Intracellular targets of antibacterial peptides
    • Cudic M., Otvos L.Jr.: Intracellular targets of antibacterial peptides. Curr. Drug Targets, 2002; 3: 101-106
    • (2002) Curr. Drug Targets , vol.3 , pp. 101-106
    • Cudic, M.1    Otvos Jr, . L.2
  • 27
    • 0141987888 scopus 로고    scopus 로고
    • A-defensins in the gastrointestinal tract
    • Cunliffe R.N.: a-defensins in the gastrointestinal tract. Mol. Immunol., 2003; 40: 463-467
    • (2003) Mol. Immunol. , vol.40 , pp. 463-467
    • Cunliffe, R.N.1
  • 28
    • 0035128862 scopus 로고    scopus 로고
    • Human defensin 5 is stored in precursor form in normal Paneth cells and is expressed by some villous epithelial cells and methaplastic Paneth cells in colon in inflammatory bowel disease
    • Cunliffe R.N., Rose F.R., Keyte J., Abberley L., Chan W.C., Mahida Y.R.: Human defensin 5 is stored in precursor form in normal Paneth cells and is expressed by some villous epithelial cells and methaplastic Paneth cells in colon in inflammatory bowel disease. Gut, 2001; 48: 176-185
    • (2001) Gut , vol.48 , pp. 176-185
    • Cunliffe, R.N.1    Rose, F.R.2    Keyte, J.3    Abberley, L.4    Chan, W.C.5    Mahida, Y.R.6
  • 29
    • 0034929327 scopus 로고    scopus 로고
    • Defensins antimicrobial peptides in the oral cavity
    • Dale B.A. Krisanaprakornkit S.: Defensins antimicrobial peptides in the oral cavity. J. Oral Pathol. Med., 2001; 30: 321-327
    • (2001) J. Oral Pathol. Med. , vol.30 , pp. 321-327
    • Dale, B.A.1    Krisanaprakornkit, S.2
  • 30
    • 29144521244 scopus 로고    scopus 로고
    • Human antimicrobial peptides: Defensins, cathelicidins and histatins
    • De Smet K., Contreras R.: Human antimicrobial peptides: defensins, cathelicidins and histatins. Biotechnol. Lett., 2005; 18: 1337-1347
    • (2005) Biotechnol. Lett. , vol.18 , pp. 1337-1347
    • De Smet, K.1    Contreras, R.2
  • 31
    • 0025811874 scopus 로고
    • Tracheal antimicrobial peptide, a cysteine-rich peptide from mammalian tracheal mucosa: Peptide isolation and cloning of a cDNA
    • Diamond G., Zasloff M., Eck H., Brasseur M., Maloy W.L., Bevins C.L.: Tracheal antimicrobial peptide, a cysteine-rich peptide from mammalian tracheal mucosa: Peptide isolation and cloning of a cDNA. Proc. Natl. Acad. Sci. USA, 1991; 88: 3952-3956
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 3952-3956
    • Diamond, G.1    Zasloff, M.2    Eck, H.3    Brasseur, M.4    Maloy, W.L.5    Bevins, C.L.6
  • 32
    • 0036892922 scopus 로고    scopus 로고
    • Chemokines meet defensins: The merging concept of chemoattractants and antimicrobial peptides in host defense
    • Durr M., Peschel A.: Chemokines meet defensins: The merging concept of chemoattractants and antimicrobial peptides in host defense. Infect. Immun., 2002; 70: 6515-6517
    • (2002) Infect. Immun. , vol.70 , pp. 6515-6517
    • Durr, M.1    Peschel, A.2
  • 33
    • 11244342346 scopus 로고    scopus 로고
    • Antibacterial activity and specificity of the six human a-defensins
    • Ericksen B., Wu Z., Lu W., Lehrer R.I.: Antibacterial activity and specificity of the six human a-defensins. Antimicrob. Agents Chemother., 2005; 49: 269-275
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 269-275
    • Ericksen, B.1    Wu, Z.2    Lu, W.3    Lehrer, R.I.4
  • 34
    • 4644322849 scopus 로고    scopus 로고
    • Bacterial evasion of innate host defenses-The Staphylococcus aureus lesson
    • Fedtke I. Gotz F. Peschel A.: Bacterial evasion of innate host defenses-The Staphylococcus aureus lesson. Int. J. Med. Microbiol., 2004; 294: 189-194
    • (2004) Int. J. Med. Microbiol. , vol.294 , pp. 189-194
    • Fedtke, I.1    Gotz, F.2    Peschel, A.3
  • 35
    • 52049088942 scopus 로고    scopus 로고
    • Physico-chemical and biophysical study of the interaction of hexaand heptaacyl lipid A from Erwinia carotovora with magainin 2-derived antimicrobial peptides
    • Fukuoka S., Howe J., Andra J., Gutsmann T., Rossle M., Brandenburg K.: Physico-chemical and biophysical study of the interaction of hexaand heptaacyl lipid A from Erwinia carotovora with magainin 2-derived antimicrobial peptides. Biochim. Biophys. Acta, 2008; 1778: 2051-2057
    • (2008) Biochim. Biophys. Acta , vol.1778 , pp. 2051-2057
    • Fukuoka, S.1    Howe, J.2    Andra, J.3    Gutsmann, T.4    Rossle, M.5    Brandenburg, K.6
  • 36
    • 0142058024 scopus 로고    scopus 로고
    • Endogenous production of antimicrobial peptides in innate immunity and human disease
    • Gallo R.I., Nizet V.: Endogenous production of antimicrobial peptides in innate immunity and human disease. Curr. Allergy Asthma Rep., 2003; 3, 402-409
    • (2003) Curr. Allergy Asthma Rep. , vol.3 , pp. 402-409
    • Gallo, R.I.1    Nizet, V.2
  • 37
    • 0036829619 scopus 로고    scopus 로고
    • Immunology. Versatile defensins
    • Ganz T.: Immunology. Versatile defensins. Science, 2002; 298: 977-979
    • (2002) Science , vol.298 , pp. 977-979
    • Ganz, T.1
  • 38
    • 0141799911 scopus 로고    scopus 로고
    • Defensins: Antimicrobial peptides of innate immunity
    • Ganz T.: Defensins: antimicrobial peptides of innate immunity. Nat. Rev. Immunol., 2003; 3: 710-720
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 710-720
    • Ganz, T.1
  • 39
    • 0037417315 scopus 로고    scopus 로고
    • Microbiology: Gut defence
    • Ganz T.: Microbiology: Gut defence. Nature, 2003; 422: 478-479
    • (2003) Nature , vol.422 , pp. 478-479
    • Ganz, T.1
  • 40
    • 0842304596 scopus 로고    scopus 로고
    • Antimicrobial polypeptides
    • Ganz T.: Antimicrobial polypeptides. J. Leukoc. Biol., 2004; 75: 34-38
    • (2004) J. Leukoc. Biol. , vol.75 , pp. 34-38
    • Ganz, T.1
  • 44
    • 0037050278 scopus 로고    scopus 로고
    • Role of membranes in the activities of antimicrobial cationic peptides
    • Hancock R.E., Rozek A.: Role of membranes in the activities of antimicrobial cationic peptides. FEMS Microbiol. Lett., 2002; 206: 143-149
    • (2002) FEMS Microbiol. Lett. , vol.206 , pp. 143-149
    • Hancock, R.E.1    Rozek, A.2
  • 46
    • 33645958888 scopus 로고    scopus 로고
    • Defensins and cathelicidins in inflammatory lung disease: Beyond antimicrobial activity
    • Hiemstra P.S.: Defensins and cathelicidins in inflammatory lung disease: beyond antimicrobial activity. Biochem. Soc. Trans., 2006; 34: 276-278
    • (2006) Biochem. Soc. Trans. , vol.34 , pp. 276-278
    • Hiemstra, P.S.1
  • 47
    • 0000617857 scopus 로고
    • Phagocytin: A bactericidal substance from polymorphonuclear leukocytes
    • Hirsch J.G.: Phagocytin: A bactericidal substance from polymorphonuclear leukocytes. J. Exp. Med., 1956; 103: 589-611
    • (1956) J. Exp. Med. , vol.103 , pp. 589-611
    • Hirsch, J.G.1
  • 48
    • 0013591239 scopus 로고
    • Degranulation of polymorphonuclear leukocytes following phagocytosis of microorganisms
    • Hirsch J.G., Cohn Z.A.: Degranulation of polymorphonuclear leukocytes following phagocytosis of microorganisms. J. Exp. Med., 1960; 112: 1005-1014
    • (1960) J. Exp. Med. , vol.112 , pp. 1005-1014
    • Hirsch, J.G.1    Cohn, Z.A.2
  • 50
    • 34548476495 scopus 로고    scopus 로고
    • Defensins induce recruitment of dendritic cells in cervical human papillomavirus-associated (pre)neoplastic lesions formed in vitro and transplanted in vivo
    • Hubert P., Herman L., Maillard C., Caberg J.H., Nikkels A., Pierad G., Foidart J.M., Noel A., Boniver J., Delvenne P.: Defensins induce recruitment of dendritic cells in cervical human papillomavirus-associated (pre)neoplastic lesions formed in vitro and transplanted in vivo. The FASEB J., 2007; 21: 2765-2775
    • (2007) The FASEB J. , vol.21 , pp. 2765-2775
    • Hubert, P.1    Herman, L.2    Maillard, C.3    Caberg, J.H.4    Nikkels, A.5    Pierad, G.6    Foidart, J.M.7    Noel, A.8    Boniver, J.9    Delvenne, P.10
  • 51
    • 0035126317 scopus 로고    scopus 로고
    • Downregulation of bactericidal peptides in enteric infection: A novel immune escape mechanism with bacterial DNA as a potential regulator
    • Islam D., Bandholtz L., Nilsson J., Wigzell H., Christensson B., Agerberth B., Gudmundsson G.: Downregulation of bactericidal peptides in enteric infection: A novel immune escape mechanism with bacterial DNA as a potential regulator. Nat. Med., 2001; 7: 180-195
    • (2001) Nat. Med. , vol.7 , pp. 180-195
    • Islam, D.1    Bandholtz, L.2    Nilsson, J.3    Wigzell, H.4    Christensson, B.5    Agerberth, B.6    Gudmundsson, G.7
  • 52
    • 1642454704 scopus 로고    scopus 로고
    • Staphylococcus aureus resists human defensins by production of staphylokinase, a novel bacterial evasion mechanism
    • Jin T., Bokarewa M., Foster T., Mitchell J., Higgins J., Tarkowski A.: Staphylococcus aureus resists human defensins by production of staphylokinase, a novel bacterial evasion mechanism. J. Immunol., 2004; 172: 1169-1176
    • (2004) J. Immunol. , vol.172 , pp. 1169-1176
    • Jin, T.1    Bokarewa, M.2    Foster, T.3    Mitchell, J.4    Higgins, J.5    Tarkowski, A.6
  • 56
    • 0033067196 scopus 로고    scopus 로고
    • Antimicrobial peptides in mammalian and insect host defence
    • Lehrer R.I., Ganz T.: Antimicrobial peptides in mammalian and insect host defence. Curr. Opin. Immunol., 1999; 11: 23-27
    • (1999) Curr. Opin. Immunol. , vol.11 , pp. 23-27
    • Lehrer, R.I.1    Ganz, T.2
  • 57
    • 0036135697 scopus 로고    scopus 로고
    • Cathelicidins: A family of endogenous antimicrobial peptides
    • Lehrer R.I., Ganz T.: Cathelicidins: A family of endogenous antimicrobial peptides. Curr. Opin. Hematol., 2002; 9: 18-22
    • (2002) Curr. Opin. Hematol. , vol.9 , pp. 18-22
    • Lehrer, R.I.1    Ganz, T.2
  • 58
    • 0036467390 scopus 로고    scopus 로고
    • Defensins of vertebrate animals
    • Lehrer R.I., Ganz T.: Defensins of vertebrate animals. Curr. Opin. Immunol., 2002; 14: 96-102
    • (2002) Curr. Opin. Immunol. , vol.14 , pp. 96-102
    • Lehrer, R.I.1    Ganz, T.2
  • 59
    • 0027474382 scopus 로고
    • Defensins: Antimicrobial and cytotoxic peptides of mammalian cells
    • Lehrer R.I., Lichtenstein A.K., Ganz T.: Defensins: antimicrobial and cytotoxic peptides of mammalian cells. Annu. Rev. Immunol., 1993; 11: 105-128
    • (1993) Annu. Rev. Immunol. , vol.11 , pp. 105-128
    • Lehrer, R.I.1    Lichtenstein, A.K.2    Ganz, T.3
  • 60
    • 0036178642 scopus 로고    scopus 로고
    • Human β-defensin-2 production in keratinocytes is regulated by interleukin-1, bacteria, and the state of differentiation
    • Liu A.Y., Destoumieux D., Wong A.V., Park C.H., Valore E.V., Liu L., Ganz T.: Human β-defensin-2 production in keratinocytes is regulated by interleukin-1, bacteria, and the state of differentiation. J. Invest. Dermatol., 2002; 118: 275-281
    • (2002) J. Invest. Dermatol. , vol.118 , pp. 275-281
    • Liu, A.Y.1    Destoumieux, D.2    Wong, A.V.3    Park, C.H.4    Valore, E.V.5    Liu, L.6    Ganz, T.7
  • 64
    • 0035884820 scopus 로고    scopus 로고
    • Cathelicidin family of antibacterial peptides CAP18 and CAP11 inhibit the expression of TNF-A by blocking the binding of LPS to CD14+ cells
    • Nagaoka I., Hirota S., Niyonsaba F., Hirata M., Adachi Y., Tamura H., Heumann D.: Cathelicidin family of antibacterial peptides CAP18 and CAP11 inhibit the expression of TNF-A by blocking the binding of LPS to CD14+ cells. J. Immunol., 2001; 167: 3329-3338
    • (2001) J. Immunol. , vol.167 , pp. 3329-3338
    • Nagaoka, I.1    Hirota, S.2    Niyonsaba, F.3    Hirata, M.4    Adachi, Y.5    Tamura, H.6    Heumann, D.7
  • 65
    • 14844314814 scopus 로고    scopus 로고
    • Identification of defensin a-6 as a potential biomarker colon adenocarcinoma
    • Nam M.J., Kee M.K., Kuick R., Hanash S.M.: Identification of defensin a-6 as a potential biomarker colon adenocarcinoma. J. Biol. Chem., 2005; 280: 8260-8265
    • (2005) J. Biol. Chem. , vol.280 , pp. 8260-8265
    • Nam, M.J.1    Kee, M.K.2    Kuick, R.3    Hanash, S.M.4
  • 66
    • 60649107215 scopus 로고    scopus 로고
    • Defensyny-wany wrodzony element ukadu odpornociowego u ssaków
    • NiedYwiedzka-Rystwej P., Deptua W.: Defensyny-wany wrodzony element ukadu odpornociowego u ssaków. Post. Hig. Med. Dow., 2008; 62: 524-529
    • (2008) Post. Hig. Med. Dow. , vol.62 , pp. 524-529
    • Niedÿwiedzka-Rystwej, P.1    Deptua, W.2
  • 67
    • 0242351607 scopus 로고    scopus 로고
    • Cathelicidins and innate defense against invasive bacterial infection
    • Nizet V., Gallo R.L.: Cathelicidins and innate defense against invasive bacterial infection. Scand. J. Infect. Dis., 2003; 35: 670-676
    • (2003) Scand. J. Infect. Dis. , vol.35 , pp. 670-676
    • Nizet, V.1    Gallo, R.L.2
  • 70
    • 0033855720 scopus 로고    scopus 로고
    • Regulation of human β-defensins by gastric epithelial cells in response to infection with Helicobacter pylori or stimulation with interleukin-1
    • O'Neil D.A., Cole S.P., Martin-Porter E., Housley M.P., Liu L., Ganz T., Kagnoff M.F.: Regulation of human β-defensins by gastric epithelial cells in response to infection with Helicobacter pylori or stimulation with interleukin-1. Infect. Immun., 2000; 68: 5413-5415
    • (2000) Infect. Immun. , vol.68 , pp. 5413-5415
    • O'Neil, D.A.1    Cole, S.P.2    Martin-Porter, E.3    Housley, M.P.4    Liu, L.5    Ganz, T.6    Kagnoff, M.F.7
  • 71
    • 0142218765 scopus 로고    scopus 로고
    • Roles of antimicrobial peptides such as defensins in innate and adaptive immunity
    • Oppenheim J.J., Biragyn A., Kwak L.W., Yang D.: Roles of antimicrobial peptides such as defensins in innate and adaptive immunity. Ann. Rheum. Dis., 2003; 62: ii17-ii21
    • (2003) Ann. Rheum. Dis. , vol.62 , pp. ii17-ii21
    • Oppenheim, J.J.1    Biragyn, A.2    Kwak, L.W.3    Yang, D.4
  • 72
    • 0033178532 scopus 로고    scopus 로고
    • Structure and organization of the human antibacterial peptide LL-37 in phospholipids membranes: Relevance to the molecular basis for its non-cell-selective activity
    • Oren Z., Lerman J.C., Gudmundsson G.H., Agerberth B., Shai Y.: Structure and organization of the human antibacterial peptide LL-37 in phospholipids membranes: relevance to the molecular basis for its non-cell-selective activity. Biochem. J., 1999; 341: 501-513
    • (1999) Biochem. J. , vol.341 , pp. 501-513
    • Oren, Z.1    Lerman, J.C.2    Gudmundsson, G.H.3    Agerberth, B.4    Shai, Y.5
  • 73
    • 1842453218 scopus 로고    scopus 로고
    • Defensin-mediated innate immunity in the small intestine
    • Ouellette A.J.: Defensin-mediated innate immunity in the small intestine. Best Pract. Res. Clin. Gastroenterol., 2004; 18: 405-419
    • (2004) Best Pract. Res. Clin. Gastroenterol. , vol.18 , pp. 405-419
    • Ouellette, A.J.1
  • 75
    • 0029819784 scopus 로고    scopus 로고
    • Paneth cell defensins: Endogenous peptide components of intestinal host defense
    • Ouellette A.J., Selsted M.E.: Paneth cell defensins: endogenous peptide components of intestinal host defense. FASEB J., 1996; 10: 1280-1289
    • (1996) FASEB J. , vol.10 , pp. 1280-1289
    • Ouellette, A.J.1    Selsted, M.E.2
  • 77
    • 0142183723 scopus 로고    scopus 로고
    • Ribosomally synthesized peptides with antimicrobial properties: Biosynthesis, structure, function, and applications
    • Papagianni M.: Ribosomally synthesized peptides with antimicrobial properties: biosynthesis, structure, function, and applications. Biotechnol. Adv., 2003; 21: 465-499
    • (2003) Biotechnol. Adv. , vol.21 , pp. 465-499
    • Papagianni, M.1
  • 78
    • 11344268155 scopus 로고    scopus 로고
    • Antimicrobial peptides: Cooperative approaches to protection
    • Patrzykat A., Douglas S.E.: Antimicrobial peptides: cooperative approaches to protection. Protein Pept. Lett., 2005; 12: 19-25
    • (2005) Protein Pept. Lett. , vol.12 , pp. 19-25
    • Patrzykat, A.1    Douglas, S.E.2
  • 79
    • 33645834508 scopus 로고    scopus 로고
    • Experimental evolution of resistance to an antimicrobial peptide
    • Perron G.G., Zasloff M., Bell G.: Experimental evolution of resistance to an antimicrobial peptide. Proc. R. Sci., 2006; 273: 251-256
    • (2006) Proc. R. Sci. , vol.273 , pp. 251-256
    • Perron, G.G.1    Zasloff, M.2    Bell, G.3
  • 80
    • 0034831625 scopus 로고    scopus 로고
    • Staphylococcal resistance to antimicrobial peptides of mammalian and bacterial origin
    • Peschel A., Collins L.V.: Staphylococcal resistance to antimicrobial peptides of mammalian and bacterial origin. Peptides 2001; 22: 1651-1659
    • (2001) Peptides , vol.22 , pp. 1651-1659
    • Peschel, A.1    Collins, L.V.2
  • 81
    • 0141987882 scopus 로고    scopus 로고
    • Defensins and acne
    • Philippott M.P.: Defensins and acne. Mol. Immunol., 2003; 40: 457-462
    • (2003) Mol. Immunol. , vol.40 , pp. 457-462
    • Philippott, M.P.1
  • 82
    • 0034194257 scopus 로고    scopus 로고
    • Large-scale synthesis and functional elements for antimicrobial activity of defensins
    • Raj P.A., Antonyraj K.J., Karunakaran T.: Large-scale synthesis and functional elements for antimicrobial activity of defensins. Biochem. J., 2000; 347: 633-641
    • (2000) Biochem. J. , vol.347 , pp. 633-641
    • Raj, P.A.1    Antonyraj, K.J.2    Karunakaran, T.3
  • 84
    • 1442330405 scopus 로고    scopus 로고
    • Interplay between antibacterial effectors: A macrophage antimicrobial peptide impairs intracellular Salmonella replication
    • Rosenberger C.M., Gallo R., Finlay B.B.: Interplay between antibacterial effectors: A macrophage antimicrobial peptide impairs intracellular Salmonella replication. Proc. Natl. Acad. Sci. USA, 2004; 101: 2422-2427
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 2422-2427
    • Rosenberger, C.M.1    Gallo, R.2    Finlay, B.B.3
  • 85
    • 0037417311 scopus 로고    scopus 로고
    • Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin
    • Salzman N.H., Ghosh D., Huttner K.M., Paterson Y., Bevins C.L.: Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin. Nature, 2003; 422: 522-526
    • (2003) Nature , vol.422 , pp. 522-526
    • Salzman, N.H.1    Ghosh, D.2    Huttner, K.M.3    Paterson, Y.4    Bevins, C.L.5
  • 86
    • 0036030617 scopus 로고    scopus 로고
    • Proteinases of common pathogenic bacteria degrade and inactivate the antibacterial peptide LL-37
    • Schmidtchen A., Frick I.M., Andersson E., Tapper H., Björck L.: Proteinases of common pathogenic bacteria degrade and inactivate the antibacterial peptide LL-37. Mol. Microbiol., 2002; 46: 157-168
    • (2002) Mol. Microbiol. , vol.46 , pp. 157-168
    • Schmidtchen, A.1    Frick, I.M.2    Andersson, E.3    Tapper, H.4    Björck, L.5
  • 88
    • 27244437074 scopus 로고    scopus 로고
    • The human cathelicidin hCAP-18
    • Serensen O.E.: The human cathelicidin hCAP-18. Dan. Med. Bull., 2005; 52: 1-10
    • (2005) Dan. Med. Bull. , vol.52 , pp. 1-10
    • Serensen, O.E.1
  • 89
    • 0032539553 scopus 로고    scopus 로고
    • Modulation of Neisseria gonorrhoeae susceptiobility to vertebrate antibacterial peptides due to a member of the resistance/nodulation/division efflux pump family
    • Shafer W.M., Qu X., Waring A.J., Lehrer R.I.: Modulation of Neisseria gonorrhoeae susceptiobility to vertebrate antibacterial peptides due to a member of the resistance/nodulation/division efflux pump family. Proc. Natl. Acad. Sci. USA, 1998; 95: 1829-1833
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 1829-1833
    • Shafer, W.M.1    Qu, X.2    Waring, A.J.3    Lehrer, R.I.4
  • 90
    • 77049272579 scopus 로고
    • Characterization of leukin: An antibacterial factor from leucocytes active against Gram-positive patogens
    • Skarnes R.C., Watson D.W.: Characterization of leukin: an antibacterial factor from leucocytes active against Gram-positive patogens. J. Exp. Med., 1956; 104: 829-845
    • (1956) J. Exp. Med. , vol.104 , pp. 829-845
    • Skarnes, R.C.1    Watson, D.W.2
  • 91
    • 12444337486 scopus 로고    scopus 로고
    • Expression and activity of β-defensins and LL-37 in the developing human lung
    • Starner T.D., Agerberth B., Gudmundsson G.H., McCray P.B.Jr: Expression and activity of β-defensins and LL-37 in the developing human lung. J. Immunol., 2005; 174: 1608-1615
    • (2005) J. Immunol. , vol.174 , pp. 1608-1615
    • Starner, T.D.1    Agerberth, B.2    Gudmundsson, G.H.3    McCray Jr, . P.B.4
  • 92
    • 33751545243 scopus 로고    scopus 로고
    • Crystal structure of human a-defensin HNP4, HD5, and HD6
    • Szyk A., Wu Z., Tucker K., Yang D. Lu W., Lubkowski J.: Crystal structure of human a-defensin HNP4, HD5, and HD6. Protein Sci., 2006; 15: 2749-2760
    • (2006) Protein Sci. , vol.15 , pp. 2749-2760
    • Szyk, A.1    Wu, Z.2    Tucker, K.3    Yang Lu, D.W.4    Lubkowski, J.5
  • 93
    • 0036893696 scopus 로고    scopus 로고
    • Antimicrobial peptides from human platelets
    • Tang Y.Q., Yeaman M.R., Selsted M.E.: Antimicrobial peptides from human platelets. Infect. Immun., 2002; 70: 6524-6533
    • (2002) Infect. Immun. , vol.70 , pp. 6524-6533
    • Tang, Y.Q.1    Yeaman, M.R.2    Selsted, M.E.3
  • 94
    • 0033569410 scopus 로고    scopus 로고
    • A cyclic antimicrobial peptide produced in primate leucocytes by the ligation of two truncated a-defensins
    • Tang Y.Q., Yuan J., Osapay G., Osapay K., Tran D., Miller C.J., Ouelette A.J., Selsted M.E.: A cyclic antimicrobial peptide produced in primate leucocytes by the ligation of two truncated a-defensins. Science 1999; 286: 498-502
    • (1999) Science , vol.286 , pp. 498-502
    • Tang, Y.Q.1    Yuan, J.2    Osapay, G.3    Osapay, K.4    Tran, D.5    Miller, C.J.6    Ouelette, A.J.7    Selsted, M.E.8
  • 95
    • 13844322065 scopus 로고    scopus 로고
    • The cathelicidins-structure, function and evolution
    • Tomasinsig L., Zanetti M.: The cathelicidins-structure, function and evolution. Curr. Protein Pept. Sci., 2005; 6: 23-34
    • (2005) Curr. Protein Pept. Sci. , vol.6 , pp. 23-34
    • Tomasinsig, L.1    Zanetti, M.2
  • 96
    • 1042290514 scopus 로고    scopus 로고
    • Hagfish intestinal antimicrobial peptides are ancient cathelicidins
    • Uzzell T., Stolzenberg E.D., Shinnar A.E., Zasloff M.: Hagfish intestinal antimicrobial peptides are ancient cathelicidins. Peptides, 2003; 24: 1655-1667
    • (2003) Peptides , vol.24 , pp. 1655-1667
    • Uzzell, T.1    Stolzenberg, E.D.2    Shinnar, A.E.3    Zasloff, M.4
  • 97
    • 0033452745 scopus 로고    scopus 로고
    • Defensins: Key players or bystander in infection, injury, and repair in the lung
    • van Wetering S., Sterk P.J., Rabe K.F., Hiemstra P.S.: Defensins: key players or bystander in infection, injury, and repair in the lung. J. Allergy Clin. Immunol., 1999; 104: 1131-1138
    • (1999) J. Allergy Clin. Immunol. , vol.104 , pp. 1131-1138
    • Van Wetering, S.1    Sterk, P.J.2    Rabe, K.F.3    Hiemstra, P.S.4
  • 100
    • 16844382886 scopus 로고    scopus 로고
    • Defensins deficiency, intestinal microbes, and clinical phenotypes of Crohn's disease
    • Wehkamp J., Schmid M., Fellermann K., Stange E.F.: Defensins deficiency, intestinal microbes, and clinical phenotypes of Crohn's disease. J. Leukoc. Biol., 2005; 77: 460-465
    • (2005) J. Leukoc. Biol. , vol.77 , pp. 460-465
    • Wehkamp, J.1    Schmid, M.2    Fellermann, K.3    Stange, E.F.4
  • 103
    • 2542480000 scopus 로고    scopus 로고
    • Multiple roles of antimicrobial defensins, cathelicidins and eosinophil-derived neurotoxin in host defense
    • Yang D., Biragyn A., Hoover D.M., Lubkowski J., Oppenheim J.J.: Multiple roles of antimicrobial defensins, cathelicidins and eosinophil-derived neurotoxin in host defense. Annu. Rev. Immunol., 2004; 22: 181-215
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 181-215
    • Yang, D.1    Biragyn, A.2    Hoover, D.M.3    Lubkowski, J.4    Oppenheim, J.J.5
  • 104
    • 0036606951 scopus 로고    scopus 로고
    • Mammalian defensins in immunity: More than just microbicidal
    • Yang D., Biragyn A., Kwak L.W., Oppenheim J.J.: Mammalian defensins in immunity: more than just microbicidal. Trends Immunol., 2002; 23: 291-296
    • (2002) Trends Immunol. , vol.23 , pp. 291-296
    • Yang, D.1    Biragyn, A.2    Kwak, L.W.3    Oppenheim, J.J.4
  • 105
    • 0034998629 scopus 로고    scopus 로고
    • Participation of mammalian defensins and cathelicidins in antimicrobial immunity: Receptors and activities of human defensins and cathelicidin (LL-37)
    • Yang D., Chertov O., Oppenheim J.J.: Participation of mammalian defensins and cathelicidins in antimicrobial immunity: receptors and activities of human defensins and cathelicidin (LL-37). J. Leukoc. Biol., 2001; 69: 691-697
    • (2001) J. Leukoc. Biol. , vol.69 , pp. 691-697
    • Yang, D.1    Chertov, O.2    Oppenheim, J.J.3
  • 107
    • 22944458199 scopus 로고    scopus 로고
    • The role cathelicidins in innate host defenses of mammals
    • Zanetti M.: The role cathelicidins in innate host defenses of mammals. Curr. Issues Mol. Biol., 2005; 7: 179-196
    • (2005) Curr. Issues Mol. Biol. , vol.7 , pp. 179-196
    • Zanetti, M.1
  • 108
    • 0028844134 scopus 로고
    • Cathelicidins: A novel protein family with common proregion and variable C-terminal antimicrobial domain
    • Zanetti M., Gennaro R., Romeo D.: Cathelicidins: A novel protein family with common proregion and variable C-terminal antimicrobial domain. FEBS Lett., 1995; 374: 1-5
    • (1995) FEBS Lett. , vol.374 , pp. 1-5
    • Zanetti, M.1    Gennaro, R.2    Romeo, D.3
  • 109
    • 0033937861 scopus 로고    scopus 로고
    • Reconstructing one of nature's designs
    • Zasloff M.: Reconstructing one of nature's designs. Trends Pharmacol. Sci., 2000; 7: 236-238
    • (2000) Trends Pharmacol. Sci. , vol.7 , pp. 236-238
    • Zasloff, M.1
  • 110
    • 0037165196 scopus 로고    scopus 로고
    • Antimicrobial peptides of multicellular organisms
    • Zasloff M.: Antimicrobial peptides of multicellular organisms. Nature, 2002; 415: 389-395
    • (2002) Nature , vol.415 , pp. 389-395
    • Zasloff, M.1
  • 111
    • 33745145802 scopus 로고    scopus 로고
    • Inducing endogenous antimicrobial peptides to battle infections
    • Zasloff M.: Inducing endogenous antimicrobial peptides to battle infections. Proc. Natl. Acad. Sci. USA, 2006; 103: 8913-8914
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 8913-8914
    • Zasloff, M.1


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