Large-scale synthesis and functional elements for the antimicrobial activity of defensins

Biochemical Journal

Volumn 347, Issue 3, 2000, Pages 633-641

  Raj, Periathamby Antony ^a,b   Antonyraj, Kavitha J ^b   Karunakaran, Thonthi ^b  

^a MARQUETTE UNIVERSITY   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

Antimicrobial agents; Antiparallel sheet peptides; Cysteine rich cationic polypeptides; Defensin analogues; Peptide disulphides

Indexed keywords

AMINO ACID; AMPHOPHILE; ARGININE; ASPARTIC ACID; DEFENSIN; VALINE;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CARBOXY TERMINAL SEQUENCE; DRUG SYNTHESIS; NONHUMAN; PORPHYROMONAS GINGIVALIS; PRIORITY JOURNAL; PROTEIN TERTIARY STRUCTURE; STREPTOCOCCUS GORDONII; STREPTOCOCCUS MUTANS; STRUCTURE ACTIVITY RELATION;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; ALPHA-DEFENSINS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS; ANTIFUNGAL AGENTS; CANDIDA ALBICANS; CELL DIVISION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; DEFENSINS; DISULFIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROSTATICS; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; NEUTROPHILS; PORPHYROMONAS GINGIVALIS; PROTEIN STRUCTURE, SECONDARY; PROTEINS; RABBITS; STREPTOCOCCUS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 0034194257     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3470633     Document Type: Article

References (45)

1. 1 Patterson-Delafield, J., Martinez, R. J. and Lehrer, R. I. (1980) Infect. Immun. 30, 180-192
2. 2 Selsted, M. E., Brown, D. M., Delange, R. J. and Lehrer, R. I. (1983) J. Biol. Chem. 258, 14485-14489
3. 3 Lehrer, R. I., Lichtenstein, A. K. and Ganz, T. (1993) Annu. Rev. Immunol. 11, 105-128
4. 4 Garzia-Olmedo, F., Molina, A., Alamillo, J. M. and Rodriguez-Palenzuela, P. (1999) Biopolymers 47, 479-491
5. 5 Diamond, G., Zasloff, M., Eck, H., Brasseue, M., Maloy, W. L. and Bevins, C. L. (1991) Proc. Natl. Acad, Sci. U.S.A. 88, 3952-3956
6. 6 Bensch, K. W., Raida, M., Magert, H. I., Schulz-Knappe, P. and Forssmann, W. G. (1995) FEBS Lett. 368, 331-335
7. 7 Schonwetter, B. S., Stolzenberg, E. D. and Zasloff, M. A. (1995) Science 267, 1645-1648
8. 8 Quellette, A. J. and Selsted, M. E. (1996) FASEB J. 10, 1280-1289
9. 9 Zhao, Z., Wang, I. and Lehrer, R. I. (1996) FEBS Lett. 396, 319-322
10. 10 Harder, J., Bartels, J., Christophers, E. and Schroder, J. M. (1997) Nature (London) 387, 861
11. 11 McCray, P. B. and Bentley, L. (1997) Am. J. Respir. Cell Mol. Biol. 16, 343-349
12. 12 Haynes, R. J., Tighe, P. J. and Dua, H. S. (1999) Br. J. Ophthamol. 83, 737-741
13. 13 Mathews, M., Jia, H. P., Guthmiller, J. M., Losh, G., Graham, S., Johnson, G. K., Tack, B. F. and McCray, Jr., P. B. (1999) Infect. Immun. 67, 2740-2745
14. 14 Lehrer, R. I., Ganz, T. and Selsted, M. E. (1988) Haematol. Oncol. Clin. N. Am. 2, 159-169
15. 15 Kagan, B. L., Ganz, T. and Lehrer, R. I. (1994) Toxicology 87, 131-149
16. 16 Diamond, G., Zasloff, M., Eck, H., Brasseue, M., Maloy, W. L. and Bevins, C. L. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 3952-3956
17. 17 Weinberg, A., Krisanaprakornkit, S. and Dale, B. A. (1998) Crit. Rev. Oral Biol. Med. 9, 399-414
18. 18 Selsted, M. E., Szklarek, D. and Leher, R. I. (1984) Infect. Immun. 46, 150-154
19. 19 Lehrer, R. I., Barton, A., Daher, K. A., Harwig, S. S., Ganz, T. and Selsted, M. E. (1989) J. Clin. Invest. 84, 553-561
20. 20 Cociancich, S., Ghazi, A., Hetru, C., Hofmann, J. A. and Letellier, L. (1993) J. Biol. Chem. 268, 19239-19245
21. 21 Hill, C. P., Yee, J. and Selsted, M. E. (1991) Science 251, 1481-1485
22. 22 Stanfield, R. L., Westbrook, E. M. and Selsted, M. E. (1988) J. Biol. Chem. 263, 5933-5935
23. 23 Levy, R. M., Blassolino, D. A. and Kitchen, D. B. (1989) Biochemistry 28, 9361-9372
24. 24 Zhang, X. L., Selsted, M. E. and Pardi, A. (1992) Biochemistry 31, 11348-11356
25. 25 Pardi, A., Zhang, X. L., Skalicky, J. J. and Yip, P. F. (1992) Biochemistry 31, 11357-11364
26. 26 Skalicky, J. J., Selsted, M. E. and Pardi, A. (1994) Proteins 20, 52-67
27. 27 Xiong, Y Q., Kupferwasser, L. I., Zack, P. M. and Bayer, A. S. (1999) Antimicrob Agents Chemother. 43, 1737-1742
28. 28 Lehrer, R. I., Ganz, T., Selsted, M. E. and Szklarek, D. (1988) J. Clin. Invest. 81, 1829-1835
29. 29 Miyasaki, K. T., Bodeau, A. L., Ganz, T., Selsted, M. E. and Lehrer, R. I. (1990) Infect. Immun. 58, 3934-3940
30. 30 Kohashi, O., Ono, T., Ohki, K., Soejima, T., Moriya, T., Umeda, A., Meno, Y., Amako, K., Funakosi, S and Masuda, M. (1992) Microbiol. Immunol. 36, 369-380
31. 31 Stewart, J. M. and Young, J. D. (1984) Solid Phase Peptide Synthesis, pp 73-95, Pierce Chemical Co., Rockford, IL
32. 32 Kaiser, E., Colescott, R. L., Bossinger, C. D. and Cook, P. I. (1970) Anal. Biochem. 34, 595-598
33. 33 Sundstrom, P. M., Nicols, E. J. and Kenny, G. E. (1987) Infect. Immun. 55, 616-620
34. 34 Raj, P. A., Edgerton, M. and Levine, M. J. (1990) J. Biol. Chem. 265, 3898-3905
35. 35 Raj, P. A., Gauri and Edgerton, M. (1997) Int. J. Oral Biol. 22, 73-80
36. 36 Antonyraj, K. J., Karunakaran, T. and Raj, P. A. (1998) Arch. Biochem. Biophys. 356, 197-206
37. 37 Dentino, A. R., Raj, P. A., Bhandary, K. K., Wilson, M. E. and Levine, M. J. (1991) J. Biol. Chem. 266, 18460-18468
38. 38 Ganz, T., Selsted, M. E., Szklarek, D., Harwig, S. S. L., Daher, K. A., Bainton, D. F. and Lehrer, R. I. (1985) J. Clin. Invest. 76, 1427-1435
39. 39 Woody, R. W. (1974) in Peptides, Polypeptides and Proteins (Blout, E. R., Bovey, F. A., Goodman, M and Lotan, N., eds.). pp. 338-350, Wiley and Sons, New York
40. 40 Khan, P. C. (1979) Methods Enzymol. 61, 339-378
41. 41 Lauth, X., Nesin, A., Briand, J. P., Roussel, J. P. and Hetru, C. (1998) Insect Biochem. Mol. Biol. 28, 1059-1066
42. 42 Rao, A. G., Rood, T., Maddox, J. and Duvick, J. (1992) Int. J. Peptide Protein Res. 40, 507-514
43. 43 Wu, M. and Hancock, R. E W. (1999) J. Biol. Chem. 274, 29-35
44. 44 Wu, M., Maier, E., Benz, R. and Hancock, R. E. W. (1999) Biochemistry 38, 7235-7242
45. 45 IUPAC-IUB Commission on Biochemical Nomenclature (1968) Biochemistry 7, 2703-2705