Ceruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMD

Investigative Ophthalmology and Visual Science

Volumn 49, Issue 6, 2008, Pages 2728-2736

  Hadziahmetovic, Majda ^a   Dentchev, Tzvete ^a   Song, Ying ^a   Haddad, Nadine ^a   He, Xining ^a   Hahn, Paul ^a   Pratico, Domenico ^b   Wen, Rong ^c   Harris, Z Leah ^d   Lambris, John D ^e   Beard, John ^f   Dunaief, Joshua L ^a,g  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b TEMPLE UNIVERSITY   (United States)

^c UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

^f PENNSYLVANIA STATE UNIVERSITY   (United States)

^g Stellar Chance Laboratories   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CERULOPLASMIN; COMPLEMENT COMPONENT C3; FERRITIN; HEPHAESTIN; IRON; ISOPROSTANE DERIVATIVE; LIPOFUSCIN; TRANSFERRIN RECEPTOR; 8,12 ISO ISOPROSTANE F2ALPHA VI; 8,12-ISO-ISOPROSTANE F2ALPHA-VI; ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; APOFERRITIN; DRUG DERIVATIVE; HEPH PROTEIN, MOUSE; MEMBRANE PROTEIN; PROSTAGLANDIN F2 ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY DETECTION; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; COMPLEMENT ACTIVATION; CONTROLLED STUDY; DISEASE COURSE; DISEASE MODEL; EPITHELIUM HYPERPLASIA; HYPERTROPHY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IRON OVERLOAD; KNOCKOUT MOUSE; MACROPHAGE; MASS FRAGMENTOGRAPHY; MORPHOLOGY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PHOTORECEPTOR; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN AGGREGATION; RETINA; RETINA DEGENERATION; RETINA MACULA AGE RELATED DEGENERATION; RETINA NEOVASCULARIZATION; STAINING; TISSUE LEVEL; ANIMAL; C57BL MOUSE; CHOROID; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; RETINA MACULA DEGENERATION;

ANIMALS; APOFERRITINS; CERULOPLASMIN; CHOROID; COMPLEMENT ACTIVATION; COMPLEMENT C3; COMPLEMENT FACTOR B; DINOPROST; DISEASE MODELS, ANIMAL; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; IRON; IRON OVERLOAD; MACROPHAGES; MACULAR DEGENERATION; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OXIDATIVE STRESS; PIGMENT EPITHELIUM OF EYE; RECEPTORS, TRANSFERRIN; RETINA; SPECTROPHOTOMETRY, ATOMIC;

EID: 47249131160     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.07-1472     Document Type: Article

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