Vulnerability to oxidative stress and different patterns of senescence in human peritoneal mesothelial cell strains

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 296, Issue 2, 2009, Pages

  Ksiazek, Krzysztof ^a,b   Mikula Pietrasik, Justyna ^a   Olijslagers, Sharon ^b   Jörres, Achim ^c   Von Zglinicki, Thomas ^b   Witowski, Janusz ^a,c  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

DNA damage; Peritoneal mesothelial cells

Indexed keywords

BETA GALACTOSIDE; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; GLUTATHIONE; OXIDIZING AGENT; REACTIVE OXYGEN METABOLITE; 8 HYDROXYDEOXYGUANOSINE; 8-HYDROXY-2'-DEOXYGUANOSINE; ANTIOXIDANT; BETA GALACTOSIDASE; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; DEOXYGUANOSINE; DRUG DERIVATIVE; H2AFX PROTEIN, HUMAN; HISTONE; LIPOFUSCIN; MESSENGER RNA;

ARTICLE; CELL STRAIN; CELL STRAIN LP 9; CONTROLLED STUDY; DNA DAMAGE; FEMALE; HUMAN; HUMAN CELL; MESOTHELIUM CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENESCENCE; TELOMERE; ADULT; CELL AGING; CELL CULTURE; CELL LINE; CELL PROLIFERATION; COMPARATIVE STUDY; ENZYMOLOGY; EPITHELIUM CELL; GENETICS; METABOLISM; OMENTUM; PERITONEUM; PHENOTYPE; TIME;

ADULT; ANTIOXIDANTS; BETA-GALACTOSIDASE; CELL AGING; CELL LINE; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DEOXYGUANOSINE; DNA DAMAGE; EPITHELIAL CELLS; FEMALE; HISTONES; HUMANS; LIPOFUSCIN; OMENTUM; OXIDATIVE STRESS; PERITONEUM; PHENOTYPE; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; TELOMERE; TIME FACTORS; YOUNG ADULT;

EID: 61949413174     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.90451.2008     Document Type: Article

References (52)

1. Akerboom TP, Sies H. Assay of glutathione, glutathione disulfide and glutathione mixed disulfides in biological samples. Methods Enzymol 77: 373-382, 1981.
2. Alcorta DA, Xiong Y, Phelps D, Hannon G, Beach D, Barrett JC. Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts. Proc Natl Acad Sci USA 93: 13742-13747, 1996.
3. Bodnar AG, Ouellette M, Frolkis M, Holt SE, Chiu CP, Morin GB, Harley CB, Shay JW, Lichtsteiner S, Wright WE. Extension of lifespan by introduction of telomerase into normal human cells. Science 279: 349-352, 1998.
4. Campisi J, and d'Adda di Fagagna F. Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol 8: 729-740, 2007.
5. Chan TM, Leung JK, Sun Y, Lai KN, Tsang RC, Yung S. Different effects of amino acid-based and glucose-based dialysate from peritoneal dialysis patients on mesothelial cell ultrastructure and function. Nephrol Dial Transplant 18: 1086-1094, 2003.
6. Connell ND, Rheinwald JG. Regulation of the cytoskeleton in mesothelial cells: reversible loss of keratin and increase in vimentin during rapid growth in culture. Cell 34: 245-253, 1983.
7. Cristofalo VJ, Sharf BB. Cellular senescence and DNA synthesis. Thymidine incorporation as a measure of population age in human diploid cells. Exp Cell Res 76: 419-427, 1973.
8. d'Adda di Fagagna F., Reaper PM, Clay-Farrace L, Fiegler H, Carr P, von Zglinicki T, Saretzki G, Carter NP, Jackson SP. A DNA damage checkpoint response in telomere-initiated senescence. Nature 426: 194-198, 2003.
9. Dickson MA, Hahn WC, Ino Y, Ronfard V, Wu JY, Weinberg RA, Louis DN, Li FP, Rheinwald JG. Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics. Mol Cell Biol 20: 1436-1447, 2000.
10. Dimri GP, Itahana K, Acosta M, Campisi J. Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor. Mol Cell Biol 20: 273-285, 2000.
11. Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C, Medrano EE, Linskens M, Rubelj I, Pereira-Smith O, Peacocke M, Campisi J. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci USA 92: 9363-9367, 1995.
12. Dowson JH, Harris SJ. Quantitative studies of the autofluorescence derived from neuronal lipofuscin. J Microsc 123: 249-258, 1981.
13. Dumont P, Burton M, Chen QM, Gonos ES, Frippiat C, Mazarati JB, Eliaers F, Remacle J, Toussaint O. Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast. Free Radic Biol Med 28: 361-373, 2000.
14. Elmadbouh I, Chen Y, Louedec L, Silberman S, Pouzet B, Meilhac O, Michel JB. Mesothelial cell transplantation in the infarct scar induces neovascularization and improves heart function. Cardiovasc Res 68: 307-317, 2005.
15. Foley-Comer AJ, Herrick SE, Al Mishlab T, Prele CM, Laurent GJ, Mutsaers SE. Evidence for incorporation of free-floating mesothelial cells as a mechanism of serosal healing. J Cell Sci 115: 1383-1389, 2002.
16. Gotloib L, Shostak A, Wajsbrot V, Kushnier R. High glucose induces a hypertrophic, senescent mesothelial cell phenotype after long in vivo exposure. Nephron 82: 164-173, 1999.
17. Herrick SE, Mutsaers SE. Mesothelial progenitor cells and their potential in tissue engineering. Int J Biochem Cell Biol 36: 621-642, 2004.
18. Itahana K, Zou Y, Itahana Y, Martinez JL, Beausejour C, Jacobs JJ, Van Lohuizen M, Band V, Campisi J, Dimri GP. Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1. Mol Cell Biol 23: 389-401, 2003.
19. Jorres A, Dinter H, Topley N, Gahl GM, Frei U, Scholz P. Inhibition of tumour necrosis factor production in endotoxin-stimulated human mononuclear leukocytes by the prostacyclin analogue iloprost: cellular mechanisms. Cytokine 9: 119-125, 1997.
20. Kaneko T, Tahara S, Taguchi T, Kondo H. Accumulation of oxidative DNA damage, 8-oxo-2′-deoxyguanosine, and change of repair systems during in vitro cellular aging of cultured human skin fibroblasts. Mutat Res 487: 19-30, 2001.
21. Kenny HA, Krausz T, Yamada SD, Lengyel E. Use of a novel 3D culture model to elucidate the role of mesothelial cells, fibroblasts and extra-cellular matrices on adhesion and invasion of ovarian cancer cells to the omentum. Int J Cancer 121: 1463-1472, 2007.
22. Ksiazek K, Breborowicz A, Jorres A, Witowski J. Oxidative stress contributes to accelerated development of the senescent phenotype in human peritoneal mesothelial cells exposed to high glucose. Free Radic Biol Med 42: 636-641, 2007.
23. Ksiazek K, Mikula-Pietrasik J, Jorres A, Witowski J. Oxidative stress-mediated early senescence contributes to the short replicative life span of human peritoneal mesothelial cells. Free Radic Biol Med 45: 460-467, 2008.
24. Ksiazek K, Passos JF, Olijslagers S, Saretzki G, Martin-Ruiz C, von Zglinicki T. Premature senescence of mesothelial cells is associated with non-telomeric DNA damage. Biochem Biophys Res Commun 362: 707-711, 2007.
25. Ksiazek K, Passos JF, Olijslagers S, von Zglinicki T. Mitochondrial dysfunction is a possible cause of accelerated senescence of mesothelial cells exposed to high glucose. Biochem Biophys Res Commun 366: 793-799, 2008.
26. Ksiazek K, Piwocka K, Brzezinska A, Sikora E, Zabel M, Breborowicz A, Jorres A, Witowski J. Early loss of proliferative potential of human peritoneal mesothelial cells in culture: the role of p16INK4a-mediated premature senescence. J Appl Physiol 100: 988-995, 2006.
27. Ksiazek K, Winckiewicz M, Staniszewski R, Breborowicz A, Witowski J. Correlation between the donor age and the proliferative lifespan of human peritoneal mesothelial cells in vitro: is TGF-beta1 a link? Exp Gerontol 42: 840-843, 2007.
28. Lopez-Cabrera M, Aguilera A, Aroeira LS, Ramirez-Huesca M, Perez-Lozano ML, Jimenez-Heffernan JA, Bajo MA, del Peso G, Sanchez-Tomero JA, Selgas R. Ex vivo analysis of dialysis effluent-derived mesothelial cells as an approach to unveiling the mechanism of peritoneal membrane failure. Perit Dial Int 26: 26-34, 2006.
29. Lorenz M, Saretzki G, Sitte N, Metzkow S, von Zglinicki T. BJ fibroblasts display high antioxidant capacity and slow telomere shortening independent of hTERT transfection. Free Radic Biol Med 31: 824-831, 2001.
30. Mutsaers SE. Mesothelial cells: their structure, function and role in serosal repair. Respirology 7: 171-191, 2002.
31. Mutsaers SE. The mesothelial cell. Int J Biochem Cell Biol 36: 9-16, 2004.
32. Mutsaers SE, Di Paolo N. Future directions in mesothelial transplantation research. Int J Artif Organs 30: 557-561, 2007.
33. Mutsaers SE, Wilkosz S. Structure and function of mesothelial cells. Cancer Treat Res 134: 1-19, 2007.
34. O'Bryan JP, Frye RA, Cogswell PC, Neubauer A, Kitch B, Prokop C, Espinosa R, III, Le Beau MM, Earp HS, Liu ET. axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase. Mol Cell Biol 11: 5016-5031, 1991.
35. Parrinello S, Coppe JP, Krtolica A, Campisi J. Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation. J Cell Sci 118: 485-496, 2005.
36. Pronk A, Leguit P, Hoynck van Papendrecht AA, Hagelen E, van Vroonhoven TJ, Verbrugh HA. A cobblestone cell isolated from the human omentum: the mesothelial cell. Isolation, identification, and growth characteristics. In Vitro Cell Dev Biol 29A: 127-134, 1993.
37. Ramirez RD, Morales CP, Herbert BS, Rohde JM, Passons C, Shay JW, Wright WE. Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions. Genes Dev 15: 398-403, 2001.
38. Serra V, von Zglinicki T, Lorenz M, Saretzki G. Extracellular superoxide dismutase is a major antioxidant in human fibroblasts and slows telomere shortening. J Biol Chem 278: 6824-6830, 2003.
39. Sitte N, Merker K, Grune T, and von Zglinicki T. Lipofuscin accumulation in proliferating fibroblasts in vitro: an indicator of oxidative stress. Exp Gerontol 36: 475-486, 2001.
40. Stylianou E, Jenner LA, Davies M, Coles GA, Williams JD. Isolation, culture and characterization of human peritoneal mesothelial cells. Kidney Int 37: 1563-1570, 1990.
41. Taniguchi T, Endo H, Chikatsu N, Uchimaru K, Asano S, Fujita T, Nakahata T, Motokura T. Expression of p21(Cip1/Waf1/Sdi1) and p27(Kip1) cyclin-dependent kinase inhibitors during human hematopoiesis. Blood 93: 4167-4178, 1999.
42. Thomas E, al Baker E, Dropcova S, Denyer S, Ostad N, Lloyd A, Kill IR, Faragher RG. Different kinetics of senescence in human fibroblasts and peritoneal mesothelial cells. Exp Cell Res 236: 355-358, 1997.
43. Van Bronswijk H, Verbrugh HA, Bos HJ, Heezius EC, Oe PL, van der MJ, Verhoef J. Cytotoxic effects of commercial continuous ambulatory peritoneal dialysis (CAPD) fluids and of bacterial exoproducts on human mesothelial cells in vitro. Perit Dial Int 9: 197-202, 1989.
44. von Zglinicki T. Oxidative stress shortens telomeres. Trends Biochem Sci 27: 339-344, 2002.
45. von Zglinicki T, Saretzki G, Docke W, Lotze C. Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: a model for senescence? Exp Cell Res 220: 186-193, 1995.
46. von Zglinicki T, Saretzki G, Ladhoff J, d'Adda di Fagagna F, Jackson SP. Human cell senescence as a DNA damage response. Mech Ageing Dev 126: 111-117, 2005.
47. Wu YJ, Parker LM, Binder NE, Beckett MA, Sinard JH, Griffiths CT, Rheinwald JG. The mesothelial keratins: a new family of cytoskeletal proteins identified in cultured mesothelial cells and nonkeratinizing epithelia. Cell 31: 693-703, 1982.
48. Yoshida T, Sheng HM, Sawada H. Use of abdominal wall with mesothelium as a substrate for reconstitution of urinary bladder wall: replacement of the mesothelium by the urothelium and complete bladder wall reconstruction. Scand J Urol Nephrol 39: 148-153, 2005.
49. Yuan H, Kaneko T, Matsuo M. Increased susceptibility of late passage human diploid fibroblasts to oxidative stress. Exp Gerontol 31: 465-474, 1996.
50. Yung S, Li FK, Chan TM. Peritoneal mesothelial cell culture and biology. Perit Dial Int 26: 162-173, 2006.
51. Zhang XY, Pettengell R, Nasiri N, Kalia V, Dalgleish AG, Barton DP. Characteristics and growth patterns of human peritoneal mesothelial cells: comparison between advanced epithelial ovarian cancer and non-ovarian cancer sources. J Soc Gynecol Investig 6: 333-340, 1999.
52. Zhu H, Tamot B, Quinton M, Walton J, Hacker RR, Li J. Influence of tissue origins and external microenvironment on porcine foetal fibroblast growth, proliferative life span and genome stability. Cell Prolif 37: 255-266, 2004.