Oxidative stress contributes to accelerated development of the senescent phenotype in human peritoneal mesothelial cells exposed to high glucose

Free Radical Biology and Medicine

Volumn 42, Issue 5, 2007, Pages 636-641

  Ksiazek, Krzysztof ^a   Breborowicz, Andrzej ^a   Jörres, Achim ^b   Witowski, Janusz ^a,b  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Free Radicals; Glucose; Mesothelial cells; Oxidative stress; Senescence

Indexed keywords

2 OXO 4 THIAZOLIDINECARBOXYLIC ACID; 8 HYDROXYDEOXYGUANOSINE; BETA GALACTOSIDASE; FIBRONECTIN; GLUCOSE; GLUTATHIONE; REACTIVE OXYGEN METABOLITE;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYPERGLYCEMIA; HYPERTROPHY; MESOTHELIUM CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SENESCENCE; STATISTICAL SIGNIFICANCE;

CELL AGING; CELLS, CULTURED; DEOXYGUANOSINE; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIUM; GLUCOSE; GLUTATHIONE PEROXIDASE; GLUTATHIONE SYNTHASE; HUMANS; OXIDATIVE STRESS; PERITONEAL CAVITY; PHENOTYPE; PYRROLIDONECARBOXYLIC ACID; REACTIVE OXYGEN SPECIES; THIAZOLIDINES;

EID: 33846829571     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2006.12.002     Document Type: Article

References (42)

1. Ben Porath I., and Weinberg R.A. The signals and pathways activating cellular senescence. Int. J Biochem. Cell Biol. 37 (2005) 961-976
2. Bokov A., Chaudhuri A., and Richardson A. The role of oxidative damage and stress in aging. Mech. Ageing Dev. 125 (2004) 811-826
3. Balaban R.S., Nemoto S., and Finkel T. Mitochondria, oxidants, and aging. Cell 120 (2005) 483-495
4. Brownlee M. The pathobiology of diabetic complications: a unifying mechanism. Diabetes 54 (2005) 1615-1625
5. King G.L., and Loeken M.R. Hyperglycemia-induced oxidative stress in diabetic complications. Histochem. Cell Biol. 122 (2004) 333-338
6. Blazer S., Khankin E., Segev Y., Ofir R., Yalon-Hacohen M., Kra-Oz Z., Gottfried Y., Larisch S., and Skorecki K.L. High glucose-induced replicative senescence: point of no return and effect of telomerase. Biochem. Biophys. Res. Commun. 296 (2002) 93-101
7. Morocutti A., Earle K.A., Sethi M., Piras G., Pal K., Richards D., Rodemann P., and Viberti G. Premature senescence of skin fibroblasts from insulin-dependent diabetic patients with kidney disease. Kidney Int. 50 (1996) 250-256
8. Mutsaers S.E. Mesothelial cells: their structure, function and role in serosal repair. Respirology 7 (2002) 171-191
9. Mortier S., DeVriese A.S., and Lameire N. Recent concepts in the molecular biology of the peritoneal membrane-Implications for more biocompatible dialysis solutions. Blood Purif. 21 (2003) 14-23
10. Gotloib L., Shostak A., Wajsbrot V., and Kushnier R. High glucose induces a hypertrophic, senescent mesothelial cell phenotype after long in vivo exposure. Nephron 82 (1999) 164-173
11. Ksiazek K., Piwocka K., Brzezinska A., Sikora E., Zabel M., Breborowicz A., Jörres A., and Witowski J. Early loss of proliferative potential of human peritoneal mesothelial cells in culture: the role of p16INK4a-mediated premature senescence. J. Appl. Physiol 100 (2006) 988-995
12. Ksiazek K., Breborowicz A., Jörres A., and Witowski J. Exposure to elevated glucose results in peritoneal mesothelial cell hypertrophy during replicative senescence in vitro. (Abstract). Nephrol. Dial. Transplant. 18 (2003) 469
13. Yung S., Li F.K., and Chan T.M. Peritoneal mesothelial cell culture and biology. Perit. Dial. Int. 26 (2006) 162-173
14. Parrinello S., Coppe J.P., Krtolica A., and Campisi J. Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation. J. Cell Sci. 118 (2005) 485-496
15. Breborowicz A., Patrikarea A., Martis L., and Oreopoulos D.G. L-2-Oxothiazolidine-4-carboxylate and N-acetylcysteine as precursors of intracellular glutathione in human peritoneal mesothelial cells. Blood Purif. 14 (1996) 1-7
16. Akerboom T.P., and Sies H. Assay of glutathione, glutathione disulfide and glutathione mixed disulfides in biological samples. Methods Enzymol. 77 (1981) 373-382
17. Rice-Evans C.A., Diplock A.T., and Symons M.C.R. Laboratory Techniques in Biochemistry and Molecular Biology. In: Burdon R.H., and van Knippenberg P.M. (Eds) (1991), Elsevier, Amsterdam 207-235
18. Dimri G.P., Lee X., Basile G., Acosta M., Scott G., Roskelley C., Medrano E.E., Linskens M., Rubelj I., Pereira-Smith O., Peacocke M., and Campisi J. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc. Natl. Acad. Sci. USA 92 (1995) 9363-9367
19. Yarborough A., Zhang Y.J., Hsu T.M., and Santella R.M. Immunoperoxidase detection of 8-hydroxydeoxyguanosine in aflatoxin B1-treated rat liver and human oral mucosal cells. Cancer Res. 56 (1996) 683-688
20. Inoguchi T., Li P., Umeda F., Yu H.Y., Kakimoto M., Imamura M., Aoki T., Etoh T., Hashimoto T., Naruse M., Sano H., Utsumi H., and Nawata H. High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD(P)H oxidase in cultured vascular cells. Diabetes 49 (2000) 1939-1945
21. Kim N.H., Rincon-Choles H., Bhandari B., Choudhury G.G., Abboud H.E., and Gorin Y. Redox dependence of glomerular epithelial cell hypertrophy in response to glucose. Am. J. Physiol. Renal Physiol. 290 (2006) F741-F751
22. Kwan J., Wang H., Munk S., Xia L., Goldberg H.J., and Whiteside C.I. In high glucose protein kinase C-zeta activation is required for mesangial cell generation of reactive oxygen species. Kidney Int. 68 (2005) 2526-2541
23. Ishibashi Y., Sugimoto T., Ichikawa Y., Akatsuka A., Miyata T., Nangaku M., Tagawa H., and Kurokawa K. Glucose dialysate induces mitochondrial DNA damage in peritoneal mesothelial cells. Perit. Dial. Int. 22 (2002) 11-21
24. Lee H.B., Yu M.R., Song J.S., and Ha H. Reactive oxygen species amplify protein kinase C signaling in high glucose-induced fibronectin expression by human peritoneal mesothelial cells. Kidney Int. 65 (2004) 1170-1179
25. Witowski J., and Knapowski J. Glycerol toxicity for human peritoneal mesothelial cells in culture: comparison with glucose. Int. J. Artif. Organs 17 (1994) 252-260
26. Kuki S., Imanishi T., Kobayashi K., Matsuo Y., Obana M., and Akasaka T. Hyperglycemia accelerated endothelial progenitor cell senescence via the activation of p38 mitogen-activated protein kinase. Circ. J. 70 (2006) 1076-1081
27. Samikkannu T., Thomas J.J., Bhat G.J., Wittman V., and Thekkumkara T.J. Acute effect of high glucose on long-term cell growth: a role for transient glucose increase in proximal tubule cell injury. Am. J. Physiol. Renal Physiol. 291 (2006) F162-F175
28. Ceriello A., dello R.P., Amstad P., and Cerutti P. High glucose induces antioxidant enzymes in human endothelial cells in culture. Evidence linking hyperglycemia and oxidative stress. Diabetes 45 (1996) 471-477
29. Harper M.E., Bevilacqua L., Hagopian K., Weindruch R., and Ramsey J.J. Ageing, oxidative stress, and mitochondrial uncoupling. Acta Physiol. Scand. 182 (2004) 321-331
30. Passos J.F., and von Zglinicki T. Mitochondria, telomeres and cell senescence. Exp. Gerontol. 40 (2005) 466-472
31. Quagliaro L., Piconi L., Assaloni R., Martinelli L., Motz E., and Ceriello A. Intermittent high glucose enhances apoptosis related to oxidative stress in human umbilical vein endothelial cells: the role of protein kinase C and NAD(P)H-oxidase activation. Diabetes 52 (2003) 2795-2804
32. Maher P. The effects of stress and aging on glutathione metabolism. Ageing Res. Rev. 4 (2005) 288-314
33. Yuan H., Kaneko T., and Matsuo M. Increased susceptibility of late passage human diploid fibroblasts to oxidative stress. Exp. Gerontol. 31 (1996) 465-474
34. Hannken T., Schroeder R., Zahner G., Stahl R.A., and Wolf G. Reactive oxygen species stimulate p44/42 mitogen-activated protein kinase and induce p27(Kip1): role in angiotensin II-mediated hypertrophy of proximal tubular cells. J. Am. Soc. Nephrol. 11 (2000) 1387-1397
35. Nevado J., Vallejo S., El Assar M., Peiro C., Sanchez-Ferrer C.F., and Rodriguez-Manas L. Changes in the human peritoneal mesothelial cells during aging. Kidney Int. 69 (2006) 313-322
36. Margetts P.J., Oh K.H., and Kolb M. Transforming growth factor-beta: importance in long-term peritoneal membrane changes. Perit. Dial. Int. 25 Suppl 3 (2005) S15-S17
37. Breborowicz A., Breborowicz M., and Oreopoulos D.G. Glucose-induced changes in the phenotype of human peritoneal mesothelial cells: effect of L-2-oxothiazolidine carboxylic acid. Am. J. Nephrol. 23 (2003) 471-476
38. Breborowicz A., Wisniewska J., Moberly J.B., and Oreopoulos D.G. l-2-Oxothiazolidine-4-carboxylic acid modulates function of peritoneal mesothelial cells in vitro. Am. J Kidney Dis. 34 (1999) 663-668
39. Breborowicz A., Witowski J., Martis L., and Oreopoulos D.G. Enhancement of viability of human peritoneal mesothelial cells with glutathione precursor: L-2-oxothiazolidine-4-carboxylate. Adv. Perit. Dial. 9 (1993) 21-24
40. Breborowicz A., Witowski J., Polubinska A., Pyda M., and Oreopoulos D. L-2-Oxothiazolidine-4-carboxylic acid reduces in vitro cytotoxicity of glucose degradation products. Nephrol. Dial. Transplant. 19 (2004) 3005-3011
41. Noh H., Kim J.S., Han K.H., Lee G.T., Song J.S., Chung S.H., Jeon J.S., Ha H., and Lee H.B. Oxidative stress during peritoneal dialysis: implications in functional and structural changes in the membrane. Kidney Int. 69 (2006) 2022-2028
42. de Magalhaes J.P. From cells to ageing: a review of models and mechanisms of cellular senescence and their impact on human ageing. Exp. Cell Res. 300 (2004) 1-10