-
1
-
-
0032542364
-
Genetic instabilities in human cancers
-
Lengauer, C., Kinzler, K. W. & Vogelstein, B. Genetic instabilities in human cancers. Nature 396, 643-649 (1998).
-
(1998)
Nature
, vol.396
, pp. 643-649
-
-
Lengauer, C.1
Kinzler, K.W.2
Vogelstein, B.3
-
2
-
-
35548978945
-
The impact of a negligent G2/M checkpoint on genomic instability and cancer induction
-
Lobrich, M. & Jeggo, P. A. The impact of a negligent G2/M checkpoint on genomic instability and cancer induction. Nature Rev. Cancer 7, 861-869 (2007).
-
(2007)
Nature Rev. Cancer
, vol.7
, pp. 861-869
-
-
Lobrich, M.1
Jeggo, P.A.2
-
3
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon, D. J. et al. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235, 177-182 (1987).
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
-
4
-
-
0023196582
-
erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells
-
Di Fiore, P. P. et al. erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells. Science 237, 178-182 (1987).
-
(1987)
Science
, vol.237
, pp. 178-182
-
-
Di Fiore, P.P.1
-
5
-
-
0023713558
-
Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene
-
Muller, W. J., Sinn, E., Pattengale, P. K., Wallace, R. & Leder, P. Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene. Cell 54, 105-115 (1988).
-
(1988)
Cell
, vol.54
, pp. 105-115
-
-
Muller, W.J.1
Sinn, E.2
Pattengale, P.K.3
Wallace, R.4
Leder, P.5
-
6
-
-
0035800507
-
Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
-
Gorre, M. E. et al. Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science 293, 876-880 (2001).
-
(2001)
Science
, vol.293
, pp. 876-880
-
-
Gorre, M.E.1
-
7
-
-
0021261878
-
Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage
-
Brodeur, G. M., Seeger, R. C., Schwab, M., Varmus, H. E. & Bishop, J. M. Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science 224, 1121-1124 (1984).
-
(1984)
Science
, vol.224
, pp. 1121-1124
-
-
Brodeur, G.M.1
Seeger, R.C.2
Schwab, M.3
Varmus, H.E.4
Bishop, J.M.5
-
8
-
-
34247634643
-
Estrogen receptor α (ESR1) gene amplification is frequent in breast cancer
-
Holst, F. et al. Estrogen receptor α (ESR1) gene amplification is frequent in breast cancer. Nature Genet. 39, 655-660 (2007).
-
(2007)
Nature Genet
, vol.39
, pp. 655-660
-
-
Holst, F.1
-
9
-
-
34047161940
-
JUN oncogene amplification and overexpression block adipocytic differentiation in highly aggressive sarcomas
-
Mariani, O. et al. JUN oncogene amplification and overexpression block adipocytic differentiation in highly aggressive sarcomas. Cancer Cell 11, 361-374 (2007).
-
(2007)
Cancer Cell
, vol.11
, pp. 361-374
-
-
Mariani, O.1
-
10
-
-
27644436744
-
Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1
-
van der Horst, E. H. et al. Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1. Proc. Natl Acad. Sci. USA 102, 15901-15906 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 15901-15906
-
-
van der Horst, E.H.1
-
11
-
-
34249075147
-
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
-
Engelman, J. A. et al. MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 316, 1039-1043 (2007).
-
(2007)
Science
, vol.316
, pp. 1039-1043
-
-
Engelman, J.A.1
-
12
-
-
0029075026
-
Amplification of the dihydrofolate reductase gene is a mechanism of acquired resistance to methotrexate in patients with acute lymphoblastic leukemia and is correlated with p53 gene mutations
-
Goker, E. et al. Amplification of the dihydrofolate reductase gene is a mechanism of acquired resistance to methotrexate in patients with acute lymphoblastic leukemia and is correlated with p53 gene mutations. Blood 86, 677-684 (1995).
-
(1995)
Blood
, vol.86
, pp. 677-684
-
-
Goker, E.1
-
13
-
-
12144290775
-
Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients
-
Wang, T. L. et al. Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients. Proc. Natl Acad. Sci. USA 101, 3089-3094 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 3089-3094
-
-
Wang, T.L.1
-
14
-
-
20044375763
-
Array comparative genomic hybridization and its applications in cancer
-
Pinkel, D. & Albertson, D. G. Array comparative genomic hybridization and its applications in cancer. Nature Genet. 37 (Suppl), S11-S17 (2005).
-
(2005)
Nature Genet
, vol.37
, Issue.SUPPL.
-
-
Pinkel, D.1
Albertson, D.G.2
-
15
-
-
33845191779
-
Genomic and transcriptional aberrations linked to breast cancer pathophysiologies
-
Chin, K. et al. Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell 10, 529-541 (2006).
-
(2006)
Cancer Cell
, vol.10
, pp. 529-541
-
-
Chin, K.1
-
16
-
-
33845291140
-
Novel patterns of genome rearrangement and their association with survival in breast cancer
-
Hicks, J. et al. Novel patterns of genome rearrangement and their association with survival in breast cancer. Genome Res. 16, 1465-1479 (2006).
-
(2006)
Genome Res
, vol.16
, pp. 1465-1479
-
-
Hicks, J.1
-
17
-
-
0001294157
-
The stability of broken ends of chromosomes in Zea mays
-
McClintock, B. The stability of broken ends of chromosomes in Zea mays. Genetics 26, 234-282 (1941).
-
(1941)
Genetics
, vol.26
, pp. 234-282
-
-
McClintock, B.1
-
18
-
-
0024792009
-
Early dihydrofolate reductase gene amplification events in CHO cells usually occur on the same chromosome arm as the original locus
-
Trask, B. J. & Hamlin, J. L. Early dihydrofolate reductase gene amplification events in CHO cells usually occur on the same chromosome arm as the original locus. Genes Dev. 3, 1913-1925 (1989).
-
(1989)
Genes Dev
, vol.3
, pp. 1913-1925
-
-
Trask, B.J.1
Hamlin, J.L.2
-
19
-
-
0025666436
-
Distinctive chromosomal structures are formed very early in the amplification of CAD genes in Syrian hamster cells
-
Smith, K. A., Gorman, P. A., Stark, M. B., Groves, R. P. & Stark, G. R. Distinctive chromosomal structures are formed very early in the amplification of CAD genes in Syrian hamster cells. Cell 63, 1219-1227 (1990).
-
(1990)
Cell
, vol.63
, pp. 1219-1227
-
-
Smith, K.A.1
Gorman, P.A.2
Stark, M.B.3
Groves, R.P.4
Stark, G.R.5
-
20
-
-
0026645532
-
Co-amplified markers alternate in megabase long chromosomal inverted repeats and cluster independently in interphase nuclei at early steps of mammalian gene amplification
-
Toledo, F., Le Roscouet, D., Buttin, G. & Debatisse, M. Co-amplified markers alternate in megabase long chromosomal inverted repeats and cluster independently in interphase nuclei at early steps of mammalian gene amplification. EMBO J. 11, 2665-2673 (1992).
-
(1992)
EMBO J
, vol.11
, pp. 2665-2673
-
-
Toledo, F.1
Le Roscouet, D.2
Buttin, G.3
Debatisse, M.4
-
21
-
-
0036849512
-
Initiation of the breakage-fusion-bridge mechanism through common fragile site activation in human breast cancer cells: The model of PIP gene duplication from a break at FRA7I
-
Ciullo, M. et al. Initiation of the breakage-fusion-bridge mechanism through common fragile site activation in human breast cancer cells: the model of PIP gene duplication from a break at FRA7I. Hum. Mol. Genet. 11, 2887-2894 (2002).
-
(2002)
Hum. Mol. Genet
, vol.11
, pp. 2887-2894
-
-
Ciullo, M.1
-
22
-
-
0036463767
-
A role for common fragile site induction in amplification of human oncogenes
-
Hellman, A. et al. A role for common fragile site induction in amplification of human oncogenes. Cancer Cell 1, 89-97 (2002).
-
(2002)
Cancer Cell
, vol.1
, pp. 89-97
-
-
Hellman, A.1
-
23
-
-
0033625440
-
A consistent pattern of RIN1 rearrangements in oral squamous cell carcinoma cell lines supports a breakage-fusion-bridge cycle model for 11q13 amplification
-
Shuster, M. I. et al. A consistent pattern of RIN1 rearrangements in oral squamous cell carcinoma cell lines supports a breakage-fusion-bridge cycle model for 11q13 amplification. Genes Chromosomes Cancer 28, 153-163 (2000).
-
(2000)
Genes Chromosomes Cancer
, vol.28
, pp. 153-163
-
-
Shuster, M.I.1
-
24
-
-
0030904279
-
Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets boundaries to early amplicons
-
Coquelle, A., Pipiras, E., Toledo, F., Buttin, G. & Debatisse, M. Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets boundaries to early amplicons. Cell 89, 215-225 (1997).
-
(1997)
Cell
, vol.89
, pp. 215-225
-
-
Coquelle, A.1
Pipiras, E.2
Toledo, F.3
Buttin, G.4
Debatisse, M.5
-
25
-
-
0036858415
-
DNA amplification by breakage/fusion/ bridge cycles initiated by spontaneous telomere loss in a human cancer cell line
-
Lo, A. W. et al. DNA amplification by breakage/fusion/ bridge cycles initiated by spontaneous telomere loss in a human cancer cell line. Neoplasia 4, 531-538 (2002).
-
(2002)
Neoplasia
, vol.4
, pp. 531-538
-
-
Lo, A.W.1
-
26
-
-
8844224076
-
Chromosome rearrangements resulting from telomere dysfunction and their role in cancer
-
Murnane, J. P. & Sabatier, L. Chromosome rearrangements resulting from telomere dysfunction and their role in cancer. Bioessays 26, 1164-1174 (2004).
-
(2004)
Bioessays
, vol.26
, pp. 1164-1174
-
-
Murnane, J.P.1
Sabatier, L.2
-
27
-
-
0000930196
-
The origin of chromosome rearrangements at early stages of AMPD2 gene amplification in Chinese hamster cells
-
Toledo, F., Buttin, G. & Debatisse, M. The origin of chromosome rearrangements at early stages of AMPD2 gene amplification in Chinese hamster cells. Curr. Biol. 3, 255-264 (1993).
-
(1993)
Curr. Biol
, vol.3
, pp. 255-264
-
-
Toledo, F.1
Buttin, G.2
Debatisse, M.3
-
28
-
-
0027471645
-
Molecular dissection of an extrachromosomal amplicon reveals a circular structure consisting of an imperfect inverted duplication
-
Nonet, G. H., Carroll, S. M., DeRose, M. L. & Wahl, G. M. Molecular dissection of an extrachromosomal amplicon reveals a circular structure consisting of an imperfect inverted duplication. Genomics 15, 543-558 (1993).
-
(1993)
Genomics
, vol.15
, pp. 543-558
-
-
Nonet, G.H.1
Carroll, S.M.2
DeRose, M.L.3
Wahl, G.M.4
-
29
-
-
0024574074
-
The importance of circular DNA in mammalian gene amplification
-
Wahl, G. M. The importance of circular DNA in mammalian gene amplification. Cancer Res. 49, 1333-1340 (1989).
-
(1989)
Cancer Res
, vol.49
, pp. 1333-1340
-
-
Wahl, G.M.1
-
30
-
-
34548441098
-
Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution
-
Bignell, G. R. et al. Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution. Genome Res. 17, 1296-1303 (2007).
-
(2007)
Genome Res
, vol.17
, pp. 1296-1303
-
-
Bignell, G.R.1
-
31
-
-
33644653015
-
Decoding the fine-scale structure of a breast cancer genome and transcriptome
-
Volik, S. et al. Decoding the fine-scale structure of a breast cancer genome and transcriptome. Genome Res. 16, 394-404 (2006).
-
(2006)
Genome Res
, vol.16
, pp. 394-404
-
-
Volik, S.1
-
32
-
-
0036272490
-
Chromosome instability as a result of double-strand breaks near telomeres in mouse embryonic stem cells
-
Lo, A. W. et al. Chromosome instability as a result of double-strand breaks near telomeres in mouse embryonic stem cells. Mol. Cell. Biol. 22, 4836-4850 (2002).
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 4836-4850
-
-
Lo, A.W.1
-
33
-
-
1342263831
-
Structure of a palindromic amplicon junction implicates microhomology-mediated end joining as a mechanism of sister chromatid fusion during gene amplification
-
Okuno, Y., Hahn, P. J. & Gilbert, D. M. Structure of a palindromic amplicon junction implicates microhomology-mediated end joining as a mechanism of sister chromatid fusion during gene amplification. Nucleic Acids Res. 32, 749-756 (2004).
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 749-756
-
-
Okuno, Y.1
Hahn, P.J.2
Gilbert, D.M.3
-
34
-
-
0014422789
-
Specific gene amplification in oocytes. Oocyte nuclei contain extrachromosomal replicas of the genes for ribosomal RNA
-
Brown, D. D. & Dawid, I. B. Specific gene amplification in oocytes. Oocyte nuclei contain extrachromosomal replicas of the genes for ribosomal RNA. Science 160, 272-280 (1968).
-
(1968)
Science
, vol.160
, pp. 272-280
-
-
Brown, D.D.1
Dawid, I.B.2
-
35
-
-
0014460844
-
Gene amplification in the oocytes of Dytiscid water beetles
-
Gall, J. G., Macgregor, H. C. & Kidston, M. E. Gene amplification in the oocytes of Dytiscid water beetles. Chromosoma 26, 169-187 (1969).
-
(1969)
Chromosoma
, vol.26
, pp. 169-187
-
-
Gall, J.G.1
Macgregor, H.C.2
Kidston, M.E.3
-
36
-
-
0019792128
-
The organization and amplification of two chromosomal domains containing Drosophila chorion genes
-
Spradling, A. C. The organization and amplification of two chromosomal domains containing Drosophila chorion genes. Cell 27, 193-201 (1981).
-
(1981)
Cell
, vol.27
, pp. 193-201
-
-
Spradling, A.C.1
-
37
-
-
0024411328
-
Recent progress in understanding mechanisms of mammalian DNA amplification
-
Stark, G. R., Debatisse, M., Giulotto, E. & Wahl, G. M. Recent progress in understanding mechanisms of mammalian DNA amplification. Cell 57, 901-908 (1989).
-
(1989)
Cell
, vol.57
, pp. 901-908
-
-
Stark, G.R.1
Debatisse, M.2
Giulotto, E.3
Wahl, G.M.4
-
38
-
-
0016202011
-
Comparison of the sequences of macro- and micronuclear DNA of Tetrahymena pyriformis
-
Yao, M. C. & Gorovsky, M. A. Comparison of the sequences of macro- and micronuclear DNA of Tetrahymena pyriformis. Chromosoma 48, 1-18 (1974).
-
(1974)
Chromosoma
, vol.48
, pp. 1-18
-
-
Yao, M.C.1
Gorovsky, M.A.2
-
39
-
-
0025222602
-
The controlling sequence for site-specific chromosome breakage in Tetrahymena
-
Yao, M. C., Yao, C. H. & Monks, B. The controlling sequence for site-specific chromosome breakage in Tetrahymena. Cell 63, 763-772 (1990).
-
(1990)
Cell
, vol.63
, pp. 763-772
-
-
Yao, M.C.1
Yao, C.H.2
Monks, B.3
-
40
-
-
0026045892
-
Short inverted repeats at a free end signal large palindromic DNA formation in Tetraihymena
-
Yasuda, L. F. & Yao, M. C. Short inverted repeats at a free end signal large palindromic DNA formation in Tetraihymena. Cell 67, 505-516 (1991).
-
(1991)
Cell
, vol.67
, pp. 505-516
-
-
Yasuda, L.F.1
Yao, M.C.2
-
41
-
-
27244436895
-
RNA-guided DNA deletion in Tetrahymena: An RNAi-based mechanism for programmed genome rearrangements
-
Yao, M. C. & Chao, J. L. RNA-guided DNA deletion in Tetrahymena: an RNAi-based mechanism for programmed genome rearrangements. Annu. Rev. Genet. 39, 537-559 (2005).
-
(2005)
Annu. Rev. Genet
, vol.39
, pp. 537-559
-
-
Yao, M.C.1
Chao, J.L.2
-
42
-
-
0028866097
-
An intramolecular recombination mechanism for the formation of the rRNA gene palindrome of Tetrahymena thermophila
-
Butler, D. K., Yasuda, L. E. & Yao, M. C. An intramolecular recombination mechanism for the formation of the rRNA gene palindrome of Tetrahymena thermophila. Mol. Cell. Biol. 15, 7117-7126 (1995).
-
(1995)
Mol. Cell. Biol
, vol.15
, pp. 7117-7126
-
-
Butler, D.K.1
Yasuda, L.E.2
Yao, M.C.3
-
43
-
-
0030582735
-
Induction of large DNA palindrome formation in yeast: Implications for gene amplification and genome stability in eukaryotes
-
Butler, D. K., Yasuda, L. E. & Yao, M. C. Induction of large DNA palindrome formation in yeast: implications for gene amplification and genome stability in eukaryotes. Cell 87, 1115-1122 (1996).
-
(1996)
Cell
, vol.87
, pp. 1115-1122
-
-
Butler, D.K.1
Yasuda, L.E.2
Yao, M.C.3
-
44
-
-
0037173105
-
Short inverted repeats initiate gene amplification through the formation of a large DNA palindrome in mammalian cells
-
Tanaka, H., Tapscott, S. J., Trask, B. J. & Yao, M. C. Short inverted repeats initiate gene amplification through the formation of a large DNA palindrome in mammalian cells. Proc. Natl Acad. Sci. USA 99, 8772-8777 (2002).
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 8772-8777
-
-
Tanaka, H.1
Tapscott, S.J.2
Trask, B.J.3
Yao, M.C.4
-
45
-
-
33745438417
-
Gene amplification: Yeast takes a turn
-
Haber, J. E. & Debatisse, M. Gene amplification: yeast takes a turn. Cell 125, 1237-1240 (2006).
-
(2006)
Cell
, vol.125
, pp. 1237-1240
-
-
Haber, J.E.1
Debatisse, M.2
-
46
-
-
7244220162
-
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1
-
Ira, G. et al. DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1. Nature 431, 1011-1017 (2004).
-
(2004)
Nature
, vol.431
, pp. 1011-1017
-
-
Ira, G.1
-
47
-
-
53349162987
-
CDK targets Sae2 to control DNA-end resection and homologous recombination
-
Huertas, P., Cortes-Ledesma, F., Sartori, A. A., Aguilera, A. & Jackson, S. P. CDK targets Sae2 to control DNA-end resection and homologous recombination. Nature 455, 689-692 (2008).
-
(2008)
Nature
, vol.455
, pp. 689-692
-
-
Huertas, P.1
Cortes-Ledesma, F.2
Sartori, A.A.3
Aguilera, A.4
Jackson, S.P.5
-
48
-
-
53649104599
-
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
-
Mimitou, E. P. & Symington, L. S. Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing. Nature 455, 770-774 (2008).
-
(2008)
Nature
, vol.455
, pp. 770-774
-
-
Mimitou, E.P.1
Symington, L.S.2
-
49
-
-
51549095956
-
Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends
-
Zhu, Z., Chung, W. H., Shim, E. Y., Lee, S. E. & Ira, G. Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends. Cell 134, 981-994 (2008).
-
(2008)
Cell
, vol.134
, pp. 981-994
-
-
Zhu, Z.1
Chung, W.H.2
Shim, E.Y.3
Lee, S.E.4
Ira, G.5
-
50
-
-
7544247595
-
Telomerase- and recombination-independent immortalization of budding yeast
-
Maringele, L. & Lydall, D. Telomerase- and recombination-independent immortalization of budding yeast. Genes Dev. 18, 2663-2675 (2004).
-
(2004)
Genes Dev
, vol.18
, pp. 2663-2675
-
-
Maringele, L.1
Lydall, D.2
-
51
-
-
24344442909
-
Human subtelomeres are hot spots of interchromosomal recombination and segmental duplication
-
Linardopoulou, E. V. et al. Human subtelomeres are hot spots of interchromosomal recombination and segmental duplication. Nature 437, 94-100 (2005).
-
(2005)
Nature
, vol.437
, pp. 94-100
-
-
Linardopoulou, E.V.1
-
52
-
-
1442327515
-
The shortest telomeres drive karyotype evolution in transformed cells
-
der-Sarkissian, H., Bacchetti, S., Cazes, L. & Londono-Vallejo, J. A. The shortest telomeres drive karyotype evolution in transformed cells. Oncogene 23, 1221-1228 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 1221-1228
-
-
der-Sarkissian, H.1
Bacchetti, S.2
Cazes, L.3
Londono-Vallejo, J.A.4
-
53
-
-
26944472376
-
Telomere dysfunction drives chromosomal instability in human mammary epithelial cells
-
Soler, D., Genesca, A., Arnedo, G., Egozcue, J. & Tusell, L. Telomere dysfunction drives chromosomal instability in human mammary epithelial cells. Genes Chromosomes Cancer 44, 339-350 (2005).
-
(2005)
Genes Chromosomes Cancer
, vol.44
, pp. 339-350
-
-
Soler, D.1
Genesca, A.2
Arnedo, G.3
Egozcue, J.4
Tusell, L.5
-
54
-
-
0037169325
-
The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements
-
Lobachev, K. S., Gordenin, D. A. & Resnick, M. A. The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements. Cell 108, 183-193 (2002).
-
(2002)
Cell
, vol.108
, pp. 183-193
-
-
Lobachev, K.S.1
Gordenin, D.A.2
Resnick, M.A.3
-
55
-
-
0035147092
-
Biased distribution of inverted and direct Alus in the human genome: Implications for insertion, exclusion, and genome stability
-
Stenger, J. E. et al. Biased distribution of inverted and direct Alus in the human genome: implications for insertion, exclusion, and genome stability. Genome Res. 11, 12-27 (2001).
-
(2001)
Genome Res
, vol.11
, pp. 12-27
-
-
Stenger, J.E.1
-
56
-
-
52049119340
-
Mus81-dependent double-strand DNA breaks at in vivo-generated cruciform structures in S. cerevisiae
-
Cote, A. G. & Lewis, S. M. Mus81-dependent double-strand DNA breaks at in vivo-generated cruciform structures in S. cerevisiae. Mol. Cell 31, 800-812 (2008).
-
(2008)
Mol. Cell
, vol.31
, pp. 800-812
-
-
Cote, A.G.1
Lewis, S.M.2
-
57
-
-
14844286404
-
Chromosomal translocations in yeast induced by low levels of DNA polymerase a model for chromosome fragile sites
-
Lemoine, F. J., Degtyareva, N. P., Lobachev, K. & Petes, T. D. Chromosomal translocations in yeast induced by low levels of DNA polymerase a model for chromosome fragile sites. Cell 120, 587-598 (2005).
-
(2005)
Cell
, vol.120
, pp. 587-598
-
-
Lemoine, F.J.1
Degtyareva, N.P.2
Lobachev, K.3
Petes, T.D.4
-
58
-
-
33745264366
-
The pattern of gene amplification is determined by the chromosomal location of hairpin-capped breaks
-
Narayanan, V., Mieczkowski, P. A., Kim, H. M., Petes, T. D. & Lobachev, K. S. The pattern of gene amplification is determined by the chromosomal location of hairpin-capped breaks. Cell 125, 1283-1296 (2006).
-
(2006)
Cell
, vol.125
, pp. 1283-1296
-
-
Narayanan, V.1
Mieczkowski, P.A.2
Kim, H.M.3
Petes, T.D.4
Lobachev, K.S.5
-
59
-
-
48249141027
-
Replication stalling at unstable inverted repeats: Interplay between DNA hairpins and fork stabilizing proteins
-
Voineagu, I., Narayanan, V., Lobachev, K. S. & Mirkin, S. M. Replication stalling at unstable inverted repeats: interplay between DNA hairpins and fork stabilizing proteins. Proc. Natl Acad. Sci. USA 105, 9936-9941 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 9936-9941
-
-
Voineagu, I.1
Narayanan, V.2
Lobachev, K.S.3
Mirkin, S.M.4
-
60
-
-
21444436726
-
Novel function of the flap endonuclease 1 complex in processing stalled DNA replication forks
-
83-89
-
Zheng, L. et al. Novel function of the flap endonuclease 1 complex in processing stalled DNA replication forks. EMBO Rep. 6, 83-89 (2005).
-
(2005)
EMBO Rep
, vol.6
-
-
Zheng, L.1
-
61
-
-
22344455087
-
A mechanism of palindromic gene amplification in Saccharomyces cerevisiae
-
Rattray, A. J., Shafer, B. K., Neelam, B. & Strathern, J. N. A mechanism of palindromic gene amplification in Saccharomyces cerevisiae. Genes Dev. 19, 1390-1399 (2005).
-
(2005)
Genes Dev
, vol.19
, pp. 1390-1399
-
-
Rattray, A.J.1
Shafer, B.K.2
Neelam, B.3
Strathern, J.N.4
-
62
-
-
13244299108
-
A novel gene amplification system in yeast based on double rolling-circle replication
-
Watanabe, T. & Horiuchi, T. A novel gene amplification system in yeast based on double rolling-circle replication. EMBO J. 24, 190-198 (2005).
-
(2005)
EMBO J
, vol.24
, pp. 190-198
-
-
Watanabe, T.1
Horiuchi, T.2
-
63
-
-
0029744334
-
DNA strand annealing is promoted by the yeast Rad52 protein
-
Mortensen, U. H., Bendixen, C., Sunjevaric, I. & Rothstein, R. DNA strand annealing is promoted by the yeast Rad52 protein. Proc. Natl Acad. Sci. USA 93, 10729-10734 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 10729-10734
-
-
Mortensen, U.H.1
Bendixen, C.2
Sunjevaric, I.3
Rothstein, R.4
-
64
-
-
0032476658
-
Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination
-
Furuse, M. et al. Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination. EMBO J. 17, 6412-6425 (1998).
-
(1998)
EMBO J
, vol.17
, pp. 6412-6425
-
-
Furuse, M.1
-
65
-
-
0032931844
-
The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance
-
Moreau, S., Ferguson, J. R. & Symington, L. S. The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance. Mol. Cell. Biol. 19, 556-566 (1999).
-
(1999)
Mol. Cell. Biol
, vol.19
, pp. 556-566
-
-
Moreau, S.1
Ferguson, J.R.2
Symington, L.S.3
-
66
-
-
0032085295
-
The 3′ to 5′ exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks
-
Paull, T. T. & Gellert, M. The 3′ to 5′ exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks. Mol. Cell 1, 969-979 (1998).
-
(1998)
Mol. Cell
, vol.1
, pp. 969-979
-
-
Paull, T.T.1
Gellert, M.2
-
67
-
-
0032555480
-
Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95
-
Trujillo, K. M., Yuan, S. S., Lee, E. Y. & Sung, P. Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95. J. Biol. Chem. 273, 21447-21450 (1998).
-
(1998)
J. Biol. Chem
, vol.273
, pp. 21447-21450
-
-
Trujillo, K.M.1
Yuan, S.S.2
Lee, E.Y.3
Sung, P.4
-
68
-
-
36248942617
-
Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex
-
Lengsfeld, B. M., Rattray, A. J., Bhaskara, V., Ghirlando, R. & Paull, T. T. Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex. Mol. Cell 28, 638-651 (2007).
-
(2007)
Mol. Cell
, vol.28
, pp. 638-651
-
-
Lengsfeld, B.M.1
Rattray, A.J.2
Bhaskara, V.3
Ghirlando, R.4
Paull, T.T.5
-
69
-
-
18344395671
-
Human MRE11 is inactivated in mismatch repair-deficient cancers
-
248-254
-
Giannini, G. et al. Human MRE11 is inactivated in mismatch repair-deficient cancers. EMBO Rep. 3, 248-254 (2002).
-
(2002)
EMBO Rep
, vol.3
-
-
Giannini, G.1
-
70
-
-
35148887112
-
Frequent alteration of DNA damage signalling and repair pathways in human colorectal cancers with microsatellite instability
-
Miquel, C. et al. Frequent alteration of DNA damage signalling and repair pathways in human colorectal cancers with microsatellite instability. Oncogene 26, 5919-5926 (2007).
-
(2007)
Oncogene
, vol.26
, pp. 5919-5926
-
-
Miquel, C.1
-
71
-
-
0035361714
-
Increased gene amplification in immortal rodent cells deficient for the DNA-dependent protein kinase catalytic subunit
-
Mondello, C. et al. Increased gene amplification in immortal rodent cells deficient for the DNA-dependent protein kinase catalytic subunit. Cancer Res. 61, 4520-4525 (2001).
-
(2001)
Cancer Res
, vol.61
, pp. 4520-4525
-
-
Mondello, C.1
-
72
-
-
0037188898
-
Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations
-
Zhu, C. et al. Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations. Cell 109, 811-821 (2002).
-
(2002)
Cell
, vol.109
, pp. 811-821
-
-
Zhu, C.1
-
73
-
-
34147205098
-
Inverted DNA repeats channel repair of distant double-strand breaks into chromatid fusions and chromosomal rearrangements
-
VanHulle, K. et al. Inverted DNA repeats channel repair of distant double-strand breaks into chromatid fusions and chromosomal rearrangements. Mol. Cell. Biol. 27, 2601-2614 (2007).
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 2601-2614
-
-
VanHulle, K.1
-
74
-
-
53349165577
-
Large inverted repeats in the vicinity of a single double-strand break strongly affect repair in yeast diploids lacking Rad51
-
Downing, B., Morgan, R., VanHulle, K., Deem, A. & Malkova, A. Large inverted repeats in the vicinity of a single double-strand break strongly affect repair in yeast diploids lacking Rad51. Mutat. Res. 645, 9-18 (2008).
-
(2008)
Mutat. Res
, vol.645
, pp. 9-18
-
-
Downing, B.1
Morgan, R.2
VanHulle, K.3
Deem, A.4
Malkova, A.5
-
75
-
-
0028820372
-
The effects of trinucleotide repeats found in human inherited disorders on palindrome inviability in Escherichia coli suggest hairpin folding preferences in vivo
-
Darlow, J. M. & Leach, D. R. The effects of trinucleotide repeats found in human inherited disorders on palindrome inviability in Escherichia coli suggest hairpin folding preferences in vivo. Genetics 141, 825-832 (1995).
-
(1995)
Genetics
, vol.141
, pp. 825-832
-
-
Darlow, J.M.1
Leach, D.R.2
-
76
-
-
0033574043
-
Triplet repeats form secondary structures that escape DNA repair in yeast
-
Moore, H., Greenwell, P. W., Liu, C. P., Arnheim, N. & Petes, T. D. Triplet repeats form secondary structures that escape DNA repair in yeast. Proc. Natl Acad. Sci. USA 96, 1504-1509 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 1504-1509
-
-
Moore, H.1
Greenwell, P.W.2
Liu, C.P.3
Arnheim, N.4
Petes, T.D.5
-
77
-
-
34047101901
-
Cruciform extrusion propensity of human translocation-mediating palindromic AT-rich repeats
-
Kogo, H. et al. Cruciform extrusion propensity of human translocation-mediating palindromic AT-rich repeats. Nucleic Acids Res. 35, 1198-1208 (2007).
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 1198-1208
-
-
Kogo, H.1
-
78
-
-
6344289639
-
Inverted repeat structure of the human genome: The X-chromosome contains a preponderance of large, highly homologous inverted repeats that contain testes genes
-
Warburton, P. E., Giordano, J., Cheung, F., Gelfand, Y. & Benson, G. Inverted repeat structure of the human genome: the X-chromosome contains a preponderance of large, highly homologous inverted repeats that contain testes genes. Genome Res. 14, 1861-1869 (2004).
-
(2004)
Genome Res
, vol.14
, pp. 1861-1869
-
-
Warburton, P.E.1
Giordano, J.2
Cheung, F.3
Gelfand, Y.4
Benson, G.5
-
79
-
-
0037047628
-
Recent segmental duplications in the human genome
-
Bailey, J. A. et al. Recent segmental duplications in the human genome. Science 297, 1003-1007 (2002).
-
(2002)
Science
, vol.297
, pp. 1003-1007
-
-
Bailey, J.A.1
-
80
-
-
0027017033
-
Charcot-Marie-Tooth type 1A duplication appears to arise from recombination at repeat sequences flanking the 1.5 Mb monomer unit
-
Pentao, L., Wise, C. A., Chinault, A. C., Patel, P. I. & Lupski, J. R. Charcot-Marie-Tooth type 1A duplication appears to arise from recombination at repeat sequences flanking the 1.5 Mb monomer unit. Nature Genet. 2, 292-300 (1992).
-
(1992)
Nature Genet
, vol.2
, pp. 292-300
-
-
Pentao, L.1
Wise, C.A.2
Chinault, A.C.3
Patel, P.I.4
Lupski, J.R.5
-
81
-
-
9144264835
-
The breakpoint region of the most common isochromosome, i(17q), in human neoplasia is characterized by a complex genomic architecture with large, palindromic, low-copy repeats
-
Barbouti, A. et al. The breakpoint region of the most common isochromosome, i(17q), in human neoplasia is characterized by a complex genomic architecture with large, palindromic, low-copy repeats. Am. J. Hum. Genet. 74, 1-10 (2004).
-
(2004)
Am. J. Hum. Genet
, vol.74
, pp. 1-10
-
-
Barbouti, A.1
-
82
-
-
55549124885
-
Copy number variation at the breakpoint region of isochromosome 17q
-
Carvalho, C. M. & Lupski, J. R. Copy number variation at the breakpoint region of isochromosome 17q. Genome Res. (2008).
-
(2008)
Genome Res
-
-
Carvalho, C.M.1
Lupski, J.R.2
-
83
-
-
33745175531
-
A preliminary comparative analysis of primate segmental duplications shows elevated substitution rates and a great-ape expansion of intrachromosomal duplications
-
She, X. et al. A preliminary comparative analysis of primate segmental duplications shows elevated substitution rates and a great-ape expansion of intrachromosomal duplications. Genome Res. 16, 576-583 (2006).
-
(2006)
Genome Res
, vol.16
, pp. 576-583
-
-
She, X.1
-
84
-
-
40649101678
-
SbcCD causes a double-strand break at a DNA palindrome in the Escherichia coli chromosome
-
Eykelenboom, J. K., Blackwood, J. K., Okely, E. & Leach, D. R. SbcCD causes a double-strand break at a DNA palindrome in the Escherichia coli chromosome. Mol. Cell 29, 644-651 (2008).
-
(2008)
Mol. Cell
, vol.29
, pp. 644-651
-
-
Eykelenboom, J.K.1
Blackwood, J.K.2
Okely, E.3
Leach, D.R.4
-
85
-
-
52949143512
-
-
Payen, C., Koszul, R., Dujon, B. & Fischer, G. Segmental duplications arise from Pol32-dependent repair of broken forks through two alternative replication-based mechanisms. PLoS Genet. 4, e1000175 (2008).
-
Payen, C., Koszul, R., Dujon, B. & Fischer, G. Segmental duplications arise from Pol32-dependent repair of broken forks through two alternative replication-based mechanisms. PLoS Genet. 4, e1000175 (2008).
-
-
-
-
86
-
-
37349109667
-
A DNA replication mechanism for generating nonrecurrent rearrangements associated with genomic disorders
-
Lee, J. A., Carvalho, C. M. & Lupski, J. R. A DNA replication mechanism for generating nonrecurrent rearrangements associated with genomic disorders. Cell 131, 1235-1247 (2007).
-
(2007)
Cell
, vol.131
, pp. 1235-1247
-
-
Lee, J.A.1
Carvalho, C.M.2
Lupski, J.R.3
-
87
-
-
0025868571
-
DNA duplication associated with Charcot-Marie-Tooth disease type 1A
-
Lupski, J. R. et al. DNA duplication associated with Charcot-Marie-Tooth disease type 1A. Cell 66, 219-232 (1991).
-
(1991)
Cell
, vol.66
, pp. 219-232
-
-
Lupski, J.R.1
-
88
-
-
3242808027
-
Large-scale copy number polymorphism in the human genome
-
Sebat, J. et al. Large-scale copy number polymorphism in the human genome. Science 305, 525-528 (2004).
-
(2004)
Science
, vol.305
, pp. 525-528
-
-
Sebat, J.1
-
89
-
-
20544462642
-
Segmental duplications and copy-number variation in the human genome
-
Sharp, A. J. et al. Segmental duplications and copy-number variation in the human genome. Am. J. Hum. Genet. 77, 78-88 (2005).
-
(2005)
Am. J. Hum. Genet
, vol.77
, pp. 78-88
-
-
Sharp, A.J.1
-
90
-
-
40449128815
-
Segmental duplications and evolutionary plasticity at tumor chromosome break-prone regions
-
Darai-Ramqvist, E. et al. Segmental duplications and evolutionary plasticity at tumor chromosome break-prone regions. Genome Res. 18, 370-379 (2008).
-
(2008)
Genome Res
, vol.18
, pp. 370-379
-
-
Darai-Ramqvist, E.1
-
91
-
-
40449141527
-
Chromosomal breakpoints in primary colon cancer cluster at sites of structural variants in the genome
-
Camps, J. et al. Chromosomal breakpoints in primary colon cancer cluster at sites of structural variants in the genome. Cancer Res. 68, 1284-1295 (2008).
-
(2008)
Cancer Res
, vol.68
, pp. 1284-1295
-
-
Camps, J.1
-
92
-
-
22744440499
-
Dynamics of mammalian chromosome evolution inferred from multispecies comparative maps
-
Murphy, W. J. et al. Dynamics of mammalian chromosome evolution inferred from multispecies comparative maps. Science 309, 613-617 (2005).
-
(2005)
Science
, vol.309
, pp. 613-617
-
-
Murphy, W.J.1
-
93
-
-
15044351972
-
Widespread and nonrandom distribution of DNA palindromes in cancer cells provides a structural platform for subsequent gene amplification
-
Tanaka, H., Bergstrom, D. A., Yao, M. C. & Tapscott, S. J. Widespread and nonrandom distribution of DNA palindromes in cancer cells provides a structural platform for subsequent gene amplification. Nature Genet. 37, 320-327 (2005).
-
(2005)
Nature Genet
, vol.37
, pp. 320-327
-
-
Tanaka, H.1
Bergstrom, D.A.2
Yao, M.C.3
Tapscott, S.J.4
-
94
-
-
33947257997
-
Intrastrand annealing leads to the formation of a large DNA palindrome and determines the boundaries of genomic amplification in human cancer
-
Tanaka, H. et al. Intrastrand annealing leads to the formation of a large DNA palindrome and determines the boundaries of genomic amplification in human cancer. Mol. Cell. Biol. 27, 1993-2002 (2007).
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 1993-2002
-
-
Tanaka, H.1
-
95
-
-
24044455869
-
Genome sequencing in microfabricated high-density picolitre reactors
-
Margulies, M. et al. Genome sequencing in microfabricated high-density picolitre reactors. Nature 437, 376-380 (2005).
-
(2005)
Nature
, vol.437
, pp. 376-380
-
-
Margulies, M.1
-
96
-
-
44349191457
-
Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing
-
Campbell, P. J. et al. Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing. Nature Genet. 40, 722-729 (2008).
-
(2008)
Nature Genet
, vol.40
, pp. 722-729
-
-
Campbell, P.J.1
-
97
-
-
43049143055
-
Mapping and sequencing of structural variation from eight human genomes
-
Kidd, J. M. et al. Mapping and sequencing of structural variation from eight human genomes. Nature 453, 56-64 (2008).
-
(2008)
Nature
, vol.453
, pp. 56-64
-
-
Kidd, J.M.1
-
98
-
-
0024347356
-
Amplified N-myc in human neuroblastoma cells is often arranged as clustered tandem repeats of differently recombined DNA
-
Amler, L. C. & Schwab, M. Amplified N-myc in human neuroblastoma cells is often arranged as clustered tandem repeats of differently recombined DNA. Mol. Cell. Biol. 9, 4903-4913 (1989).
-
(1989)
Mol. Cell. Biol
, vol.9
, pp. 4903-4913
-
-
Amler, L.C.1
Schwab, M.2
-
99
-
-
4143127655
-
Alternative mechanisms of gene amplification in human cancers
-
Kuwahara, Y. et al. Alternative mechanisms of gene amplification in human cancers. Genes Chromosomes Cancer 41, 125-132 (2004).
-
(2004)
Genes Chromosomes Cancer
, vol.41
, pp. 125-132
-
-
Kuwahara, Y.1
-
100
-
-
0026580718
-
Suppression of gene amplification in human cell hybrids
-
Tlsty, T. D., White, A. & Sanchez, J. Suppression of gene amplification in human cell hybrids. Science 255, 1425-1427 (1992).
-
(1992)
Science
, vol.255
, pp. 1425-1427
-
-
Tlsty, T.D.1
White, A.2
Sanchez, J.3
-
101
-
-
0026801062
-
Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
-
Livingstone, L. R. et al. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell 70, 923-935 (1992).
-
(1992)
Cell
, vol.70
, pp. 923-935
-
-
Livingstone, L.R.1
-
102
-
-
0026801977
-
Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
-
Yin, Y., Tainsky, M. A., Bischoff, F. Z., Strong, L. C. & Wahl, G. M. Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell 70, 937-948 (1992).
-
(1992)
Cell
, vol.70
, pp. 937-948
-
-
Yin, Y.1
Tainsky, M.A.2
Bischoff, F.Z.3
Strong, L.C.4
Wahl, G.M.5
-
103
-
-
0033578066
-
Mutant p53 proteins stimulate spontaneous and radiation-induced intrachromosomal homologous recombination independently of the alteration of the transactivation activity and of the G1 checkpoint
-
Saintigny, Y., Rouillard, D., Chaput, B., Soussi, T. & Lopez, B. S. Mutant p53 proteins stimulate spontaneous and radiation-induced intrachromosomal homologous recombination independently of the alteration of the transactivation activity and of the G1 checkpoint. Oncogene 18, 3553-3563 (1999).
-
(1999)
Oncogene
, vol.18
, pp. 3553-3563
-
-
Saintigny, Y.1
Rouillard, D.2
Chaput, B.3
Soussi, T.4
Lopez, B.S.5
-
104
-
-
2442477786
-
p53's double life: Transactivation-independent repression of homologous recombination
-
Bertrand, P., Saintigny, Y. & Lopez, B. S. p53's double life: transactivation-independent repression of homologous recombination. Trends Genet. 20, 235-243 (2004).
-
(2004)
Trends Genet
, vol.20
, pp. 235-243
-
-
Bertrand, P.1
Saintigny, Y.2
Lopez, B.S.3
-
105
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine, A. J. p53, the cellular gatekeeper for growth and division. Cell 88, 323-331 (1997).
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
106
-
-
52949109260
-
Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation
-
Buis, J. et al. Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation. Cell 135, 85-96 (2008).
-
(2008)
Cell
, vol.135
, pp. 85-96
-
-
Buis, J.1
-
107
-
-
36549060102
-
Human CtIP promotes DNA end resection
-
Sartori, A. A. et al. Human CtIP promotes DNA end resection. Nature 450, 509-514 (2007).
-
(2007)
Nature
, vol.450
, pp. 509-514
-
-
Sartori, A.A.1
-
108
-
-
59949091427
-
A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome
-
Hampton, O. A. et al. A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome. Genome Res. (2009).
-
(2009)
Genome Res
-
-
Hampton, O.A.1
-
109
-
-
0021690129
-
Constitutive fragile sites and cancer
-
Yunis, J. J. & Soreng, A. L. Constitutive fragile sites and cancer. Science 226, 1199-1204 (1984).
-
(1984)
Science
, vol.226
, pp. 1199-1204
-
-
Yunis, J.J.1
Soreng, A.L.2
-
110
-
-
33947581390
-
The impact of translocations and gene fusions on cancer causation
-
Mitelman, F., Johansson, B. & Mertens, F. The impact of translocations and gene fusions on cancer causation. Nature Rev. Cancer 7, 233-245 (2007).
-
(2007)
Nature Rev. Cancer
, vol.7
, pp. 233-245
-
-
Mitelman, F.1
Johansson, B.2
Mertens, F.3
-
111
-
-
0032759353
-
Long inverted repeats are an at-risk motif for recombination in mammalian cells
-
Waldman, A. S., Tran, H., Goldsmith, E. C. & Resnick, M. A. Long inverted repeats are an at-risk motif for recombination in mammalian cells. Genetics 153, 1873-1883 (1999).
-
(1999)
Genetics
, vol.153
, pp. 1873-1883
-
-
Waldman, A.S.1
Tran, H.2
Goldsmith, E.C.3
Resnick, M.A.4
-
112
-
-
33144472660
-
Genetic variation affects de novo translocation frequency
-
Kato, T. et al. Genetic variation affects de novo translocation frequency. Science 311, 971 (2006).
-
(2006)
Science
, vol.311
, pp. 971
-
-
Kato, T.1
-
113
-
-
34547121725
-
A common genetic risk factor for colorectal and prostate cancer
-
Haiman, C. A. et al. A common genetic risk factor for colorectal and prostate cancer. Nature Genet. 39, 954-956 (2007).
-
(2007)
Nature Genet
, vol.39
, pp. 954-956
-
-
Haiman, C.A.1
-
114
-
-
34547498546
-
A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21
-
Tomlinson, I. et al. A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. Nature Genet. 39, 984-988 (2007).
-
(2007)
Nature Genet
, vol.39
, pp. 984-988
-
-
Tomlinson, I.1
-
115
-
-
0026495364
-
Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors
-
Kallioniemi, A. et al. Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors. Science 258, 818-821 (1992).
-
(1992)
Science
, vol.258
, pp. 818-821
-
-
Kallioniemi, A.1
-
116
-
-
17344371740
-
High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays
-
Pinkel, D. et al. High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays. Nature Genet. 20, 207-211 (1998).
-
(1998)
Nature Genet
, vol.20
, pp. 207-211
-
-
Pinkel, D.1
-
117
-
-
10744233914
-
A tiling resolution DNA microarray with complete coverage of the human genome
-
Ishkanian, A. S. et al. A tiling resolution DNA microarray with complete coverage of the human genome. Nature Genet. 36, 299-303 (2004).
-
(2004)
Nature Genet
, vol.36
, pp. 299-303
-
-
Ishkanian, A.S.1
-
118
-
-
33747587864
-
Model-based analysis of tiling-arrays for ChIP-chip
-
Johnson, W. E. et al. Model-based analysis of tiling-arrays for ChIP-chip. Proc. Natl Acad. Sci. USA 103, 12457-12462 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 12457-12462
-
-
Johnson, W.E.1
-
119
-
-
52949141845
-
Integrated detection and population-genetic analysis of SNPs and copy number variation
-
McCarroll, S. A. et al. Integrated detection and population-genetic analysis of SNPs and copy number variation. Nature Genet. (2008).
-
(2008)
Nature Genet
-
-
McCarroll, S.A.1
-
120
-
-
41149140876
-
The fine-scale and complex architecture of human copy-number variation
-
Perry, G. H. et al. The fine-scale and complex architecture of human copy-number variation. Am. J. Hum. Genet. 82, 685-695 (2008).
-
(2008)
Am. J. Hum. Genet
, vol.82
, pp. 685-695
-
-
Perry, G.H.1
-
121
-
-
23044482497
-
Basal body duplication and maintenance require one member of the Tetrahymena thermophila centrin gene family
-
Stemm-Wolf, A. J. et al. Basal body duplication and maintenance require one member of the Tetrahymena thermophila centrin gene family. Mol. Biol. Cell 16, 3606-3619 (2005).
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 3606-3619
-
-
Stemm-Wolf, A.J.1
-
122
-
-
0031029916
-
Germ-line knockout heterokaryons of an essential alpha-tubulin gene enable high-frequency gene replacement and a test of gene transfer from somatic to germ-line nuclei in Tetrahymena thermophila
-
Hai, B. & Gorovsky, M. A. Germ-line knockout heterokaryons of an essential alpha-tubulin gene enable high-frequency gene replacement and a test of gene transfer from somatic to germ-line nuclei in Tetrahymena thermophila. Proc. Natl Acad. Sci. USA 94, 1310-1315 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 1310-1315
-
-
Hai, B.1
Gorovsky, M.A.2
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