Oxidized Alkyl Phospholipids are Specific, High Affinity Peroxisome Proliferator-activated Receptor γ Ligands and Agonists

Journal of Biological Chemistry

Volumn 276, Issue 19, 2001, Pages 16015-16023

  Davies, Sean S ^a,e   Pontsler, Aaron V ^a,b   Marathe, Gopal K ^a,b   Harrison, Kathleen A ^d   Murphy, Robert C ^d   Hinshaw, Jerald C ^b   Prestwich, Glenn D ^b   St Hilaire, Andy ^a,b   Prescott, Stephen M ^a,c   Zimmerman, Guy A ^a,b   McIntyre, Thomas M ^a,b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF UTAH   (United States)

^c UNIVERSITY OF UTAH   (United States)

^d NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^e VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENES; OXIDATION; PHOSPHOLIPIDS;

MONOCYTES;

ENZYMES;

CD36 ANTIGEN; ENZYME; FLIPPASE; HEXADECYLAZELAOYLPHOSPHATIDYLCHOLINE; LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHATIDYLCHOLINE; PHOSPHOLIPASE A1; PHOSPHOLIPID; PHOSPHOLIPID DERIVATIVE; ROSIGLITAZONE; UNCLASSIFIED DRUG; 2,4 THIAZOLIDINEDIONE DERIVATIVE; CELL RECEPTOR; DNA BINDING PROTEIN; HYBRID PROTEIN; LIGAND; THIAZOLE DERIVATIVE; TRANSCRIPTION FACTOR;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; GENE INDUCTION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INFLAMMATION; LIGAND BINDING; LIPID OXIDATION; MONOCYTE; PRIORITY JOURNAL; REPORTER GENE; SIGNAL TRANSDUCTION; ANIMAL; BINDING COMPETITION; BINDING SITE; CELL LINE; CHEMISTRY; DRUG POTENTIATION; GENETIC TRANSFECTION; GENETICS; IN VITRO STUDY; KINETICS; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY;

ANIMALS; ANTIGENS, CD36; BINDING SITES; BINDING, COMPETITIVE; CELL LINE; DNA-BINDING PROTEINS; GENES, REPORTER; HUMANS; KINETICS; LIGANDS; LIPOPROTEINS, LDL; MONOCYTES; OXIDATION-REDUCTION; PHOSPHATIDYLCHOLINES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECOMBINANT FUSION PROTEINS; THIAZOLES; THIAZOLIDINEDIONES; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 0035844217     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100878200     Document Type: Article

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