Cardiomyocyte-specffic knockout and agonist of peroxisome proliferator-activated receptor-γ both induce cardiac hypertrophy in mice

Circulation Research

Volumn 97, Issue 4, 2005, Pages 372-379

  Duan, Sheng Zhong ^a   Ivashchenko, Christine Y ^a   Russell, Mark W ^a   Milstone, David S ^a,b   Mortensen, Richard M ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Cardiac hypertrophy; Cardiomyocytes; Knockout; Peroxisome proliferator activated receptor ; Thiazolidinediones

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ATRIAL NATRIURETIC FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; MYOSIN HEAVY CHAIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN KINASE B; ROSIGLITAZONE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG INDUCED DISEASE; DRUG MECHANISM; GENE EXPRESSION; HEART DEVELOPMENT; HEART HYPERTROPHY; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; ANIMAL; CARDIOMEGALY; DRUG ANTAGONISM; DRUG POTENTIATION; GENETICS; MALE; MOUSE MUTANT; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; SYSTOLE;

ANIMALS; ATRIAL NATRIURETIC FACTOR; CARDIOMEGALY; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, KNOCKOUT; MYOCYTES, CARDIAC; MYOSIN HEAVY CHAINS; NF-KAPPA B; PHOSPHORYLATION; PPAR GAMMA; SYSTOLE; THIAZOLIDINEDIONES;

EID: 24044476859     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000179226.34112.6d     Document Type: Article

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