Differential activation of Gq/11 and Gi3 proteins at 5-hydroxytryptamine2C receptors revealed by antibody capture assays: Influence of receptor reserve and relationship, to agonist-directed trafficking

Molecular Pharmacology

Volumn 62, Issue 3, 2002, Pages 578-589

  Cussac, Didier ^a   Newman Tancredi, Adrian ^a   Duqueyroix, Delphine ^a   Pasteau, Valérie ^a   Millan, Mark J ^a  

^a INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2 (6 CHLORO 5 FLUORO 1 INDOLYL) 1 METHYLETHYLAMINE; 2 ETHOXY 1(2H) QUINOLINECARBOXYLIC ACID ETHYL ESTER; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; 6 CHLORO 5 METHYL 1 [[2 [(2 METHYL 3 PYRIDYL)OXY] 5 PYRIDYL]CARBAMOYL]INDOLINE; G PROTEIN COUPLED RECEPTOR; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN 3; ISOPROTEIN; LISURIDE; LYSERGIDE; PERTUSSIS TOXIN; PROTEIN GQ 11; RECEPTOR RESERVE; SEROTONIN; SEROTONIN 2C RECEPTOR; SULFUR 35; UNCLASSIFIED DRUG;

AGONIST; ANIMAL CELL; ANTIBODY CAPTURE ASSAY; ARTICLE; BINDING ASSAY; CHO CELL; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; IMMUNOASSAY; ISOTOPE LABELING; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; RECEPTOR DENSITY; SCINTIGRAPHY; SCINTILLATION PROXIMITY ASSAY; TECHNIQUE;

ALKYLATION; ANIMALS; ANTIBODY SPECIFICITY; BIOLOGICAL TRANSPORT; CELL MEMBRANE; CHO CELLS; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; PERTUSSIS TOXIN; PROTEIN ISOFORMS; QUINOLINES; RECEPTOR, SEROTONIN, 5-HT2C; RECEPTORS, SEROTONIN; SULFUR RADIOISOTOPES; TRANSFECTION; VIRULENCE FACTORS, BORDETELLA;

EID: 0036765561     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.62.3.578     Document Type: Article

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