Inhibition of arachidonic acid cascade attenuates the induction of c-FOS proteins by DOI, 5-HT2A/2C receptor agonist, in the rat cortex

Polish Journal of Pharmacology

Volumn 54, Issue 1, 2002, Pages 73-76

  Maćkowiak, Marzena ^a   Czyrak, Anna ^a   Wȩdzony, Krzysztof ^a  

^a INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

Arachidonic acid; c Fos protein; Dexamethasone; DOI; Indomethacin; Phospholipase A2

Indexed keywords

4 IODO 2,5 DIMETHOXYAMPHETAMINE; AMPA RECEPTOR; ARACHIDONIC ACID; DEXAMETHASONE; INDOMETACIN; PHOSPHOLIPASE A2; PROSTAGLANDIN SYNTHASE; PROTEIN C FOS; SEROTONIN 2A ANTAGONIST; SEROTONIN 2A RECEPTOR; SEROTONIN 2C ANTAGONIST; SEROTONIN 2C RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATTENUATION; BIOTRANSFORMATION; BRAIN CORTEX; BRAIN NERVE CELL; CELL COUNT; CONTROLLED STUDY; DOSE RESPONSE; IMMUNOHISTOCHEMISTRY; MALE; METABOLITE; NONHUMAN; PARIETAL LOBE; PROTEIN EXPRESSION; RAT;

AMPHETAMINES; ANIMALS; ARACHIDONIC ACID; DEXAMETHASONE; INDOMETHACIN; MALE; PARIETAL LOBE; PHOSPHOLIPASES A; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, WISTAR; SEROTONIN AGONISTS;

EID: 0036209432     PISSN: 12306002     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Cyclooxygenase-2 induction in cerebral cortex: An intracellular response to synaptic excitation
2. Serotonin stimulates phospholipase A2 and the release of arachidonic acid in hippocampal neurons by a type 2 serotonin receptor that is independent of inositol-phospholipid hydrolysis
3. N-methyl-D-aspartate receptors activate transcription of c-fos and NGFI-A by distinct phospholipase A2-requiring intracellular signaling pathways
4. Prostaglandin F2alpha is required for NMDA receptor-mediated induction of c-fos mRNA in dentate gyrus neurons
5. Ionotropic glutamate receptor subtypes activate c-fos transcription by distinct calcium-requiring intracellular signaling pathways
6. c-Fos proteins, induced by the serotonin receptor agonist DOI, are not expressed in 5-HT2A positive cortical neurons
7. The electrophysiology of prefrontal serotonin systems: Therapeutic implications for mood and psychosis
8. DOI-induced activation of the cortex: Dependence on 5-HT2A heteroceptors on thalamocortical glutamatergic neurons
9. Arachidonic acid cascade and signal transduction