Mouse models of mitochondrial DNA defects and their relevance for human disease

EMBO Reports

Volumn 10, Issue 2, 2009, Pages 137-143

  Tyynismaa, Henna ^a,b   Suomalainen, Anu ^a,b  

^a UNIVERSITY OF HELSINKI   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE; MITOCHONDRIAL DNA; MUTANT PROTEIN; NUCLEAR PROTEIN; NUCLEAR RESPIRATORY FACTOR 1; NUCLEOSIDE; NUCLEOTIDE; RIBONUCLEOTIDE REDUCTASE; SINGLE STRANDED DNA BINDING PROTEIN; THYMIDINE KINASE; THYMIDINE KINASE 2; THYMIDINE PHOSPHORYLASE; UNCLASSIFIED DRUG;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; CELL PROLIFERATION; DNA MODIFICATION; DNA SYNTHESIS; DOUBLE STRANDED DNA BREAK; ENVIRONMENTAL STRESS; GENE DUPLICATION; GENE SEGREGATION; GENE TARGETING; GENETIC ENGINEERING; MITOCHONDRIAL DNA DISORDER; MITOSIS; MOUSE; MUTAGENESIS; NONHUMAN; PATHOGENESIS; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; REVIEW; SYNAPTOSOME;

ANIMALS; CELL CYCLE PROTEINS; DISEASE MODELS, ANIMAL; DNA HELICASES; DNA, MITOCHONDRIAL; DNA-DIRECTED DNA POLYMERASE; GENE DOSAGE; GENES, MITOCHONDRIAL; GENETIC ENGINEERING; HUMANS; MICE; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MICE, TRANSGENIC; MITOCHONDRIAL DISEASES; MITOCHONDRIAL PROTEINS; PHENOTYPE; RIBONUCLEOTIDE REDUCTASES; THYMIDINE KINASE;

EID: 59649115646     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2008.242     Document Type: Review

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