메뉴 건너뛰기




Volumn 71, Issue 2-3 SPEC. ISS., 2006, Pages 372-378

Antivirals for influenza: Historical perspectives and lessons learned

Author keywords

Amantadine; Antiviral resistance; Influenza; Neuraminidase; Oseltamivir; Pathogenesis; Zanamivir

Indexed keywords

AMANTADINE; ANTIVIRUS AGENT; OSELTAMIVIR; RIMANTADINE; SIALIDASE INHIBITOR; ZANAMIVIR;

EID: 33747156960     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.antiviral.2006.05.016     Document Type: Short Survey
Times cited : (84)

References (87)
  • 1
    • 12944314951 scopus 로고    scopus 로고
    • Generation and characterization of recombinant influenza A (H1N1) viruses harboring amantadine resistance mutations
    • Abed Y., Goyette N., and Boivin G. Generation and characterization of recombinant influenza A (H1N1) viruses harboring amantadine resistance mutations. Antimicrob. Agents Chemother. 49 2 (2005) 556-559
    • (2005) Antimicrob. Agents Chemother. , vol.49 , Issue.2 , pp. 556-559
    • Abed, Y.1    Goyette, N.2    Boivin, G.3
  • 4
    • 25844438380 scopus 로고    scopus 로고
    • Incidence of adamantane resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern
    • Bright R.A., Medina M.J., Xu X., Perez-Oronoz G., Wallis T.R., Davis X.M., Povinelli L., Cox N.J., and Klimov A.I. Incidence of adamantane resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern. Lancet 366 (2005) 1175-1181
    • (2005) Lancet , vol.366 , pp. 1175-1181
    • Bright, R.A.1    Medina, M.J.2    Xu, X.3    Perez-Oronoz, G.4    Wallis, T.R.5    Davis, X.M.6    Povinelli, L.7    Cox, N.J.8    Klimov, A.I.9
  • 5
    • 33644536465 scopus 로고    scopus 로고
    • Adamantane resistance among influenza A viruses isolated early during the 2005-2006 influenza season in the United States
    • Bright R.A., Shay D.K., Shu B., Cox N.J., and Klimov A.I. Adamantane resistance among influenza A viruses isolated early during the 2005-2006 influenza season in the United States. JAMA (2006) 295
    • (2006) JAMA , pp. 295
    • Bright, R.A.1    Shay, D.K.2    Shu, B.3    Cox, N.J.4    Klimov, A.I.5
  • 6
    • 0026508847 scopus 로고
    • The 2.2 A resolution crystal structure of influenza B neuraminidase and its complex with sialic acid
    • Burmeister W.P., Ruigrok R.W., and Cusack S. The 2.2 A resolution crystal structure of influenza B neuraminidase and its complex with sialic acid. EMBO Journal. 11 1 (1992) 49-56
    • (1992) EMBO Journal. , vol.11 , Issue.1 , pp. 49-56
    • Burmeister, W.P.1    Ruigrok, R.W.2    Cusack, S.3
  • 7
    • 84958045787 scopus 로고
    • Mucins and mucoids in relation to influenza virus action, III: inhibition of virus haemagglutination by glandular mucins
    • Burnet F.M. Mucins and mucoids in relation to influenza virus action, III: inhibition of virus haemagglutination by glandular mucins. Aust J Exp Biol Med Sci 26 (1948) 371-379
    • (1948) Aust J Exp Biol Med Sci , vol.26 , pp. 371-379
    • Burnet, F.M.1
  • 8
    • 8544231009 scopus 로고
    • Mucin as substrate of enzyme action by viruses of the mumps influenza group
    • Burnet F.M., McCrea J.F., and Anderson S.G. Mucin as substrate of enzyme action by viruses of the mumps influenza group. Nature 160 (1947) 404-405
    • (1947) Nature , vol.160 , pp. 404-405
    • Burnet, F.M.1    McCrea, J.F.2    Anderson, S.G.3
  • 9
  • 10
    • 0032779292 scopus 로고    scopus 로고
    • Safety and efficacy of intravenous zanamivir in preventing experimental human influenza A virus infection
    • Calfee D.P., Peng A.W., Cass L., Lobo M., and Hayden F.G. Safety and efficacy of intravenous zanamivir in preventing experimental human influenza A virus infection. Antimicrob. Agents Chemother. 43 7 (1999) 1616-1620
    • (1999) Antimicrob. Agents Chemother. , vol.43 , Issue.7 , pp. 1616-1620
    • Calfee, D.P.1    Peng, A.W.2    Cass, L.3    Lobo, M.4    Hayden, F.G.5
  • 11
    • 0036224388 scopus 로고    scopus 로고
    • Influenza virus carrying neuraminidase with reduced sensitivity to oseltamivir carboxylate has altered properties in vitro and is compromised for infectivity and replicative ability in vivo
    • Carr J., Ives J., Kelly L., Lambkin R., Oxford J., Mendel D., Tai L., and Roberts N. Influenza virus carrying neuraminidase with reduced sensitivity to oseltamivir carboxylate has altered properties in vitro and is compromised for infectivity and replicative ability in vivo. Antivir. Res. 54 2 (2002) 79-88
    • (2002) Antivir. Res. , vol.54 , Issue.2 , pp. 79-88
    • Carr, J.1    Ives, J.2    Kelly, L.3    Lambkin, R.4    Oxford, J.5    Mendel, D.6    Tai, L.7    Roberts, N.8
  • 13
    • 0020633096 scopus 로고
    • Structure of the catalytic and antigenic sites in influenza virus neuraminidase
    • Colman P.M., Varghese J.N., and Laver W.G. Structure of the catalytic and antigenic sites in influenza virus neuraminidase. Nature 303 5912 (1983) 41-44
    • (1983) Nature , vol.303 , Issue.5912 , pp. 41-44
    • Colman, P.M.1    Varghese, J.N.2    Laver, W.G.3
  • 17
    • 0031925539 scopus 로고    scopus 로고
    • Effect of rimantadine treatment on clinical manifestations and otologic complications in adults experimentally infected with influenza A (H1N1) virus
    • Doyle W.J., Skoner D., Alper C.M., Allen G., Moody S.A., Seroky J., and Hayden F.G. Effect of rimantadine treatment on clinical manifestations and otologic complications in adults experimentally infected with influenza A (H1N1) virus. J. Infect. Dis. 177 (1998) 1260-1265
    • (1998) J. Infect. Dis. , vol.177 , pp. 1260-1265
    • Doyle, W.J.1    Skoner, D.2    Alper, C.M.3    Allen, G.4    Moody, S.A.5    Seroky, J.6    Hayden, F.G.7
  • 19
    • 0037397232 scopus 로고    scopus 로고
    • A population-dynamic model for evaluating the potential spread of drug-resistant influenza virus infections during community-based use of antivirals
    • Ferguson N.M., Mallett S., Jackson H., Roberts N., and Ward P. A population-dynamic model for evaluating the potential spread of drug-resistant influenza virus infections during community-based use of antivirals. J. Antimicrob. Chemother. 51 (2003) 977-990
    • (2003) J. Antimicrob. Chemother. , vol.51 , pp. 977-990
    • Ferguson, N.M.1    Mallett, S.2    Jackson, H.3    Roberts, N.4    Ward, P.5
  • 21
    • 0032873656 scopus 로고    scopus 로고
    • Nasal cytokine and chemokine responses in experimental influenza A virus infection: results of a placebo-controlled trial of intravenous zanamivir treatment
    • Fritz R.S., Hayden F.G., Calfee D.P., Cass L., Peng A.W., Alvord G., Strober W., and Straus S.E. Nasal cytokine and chemokine responses in experimental influenza A virus infection: results of a placebo-controlled trial of intravenous zanamivir treatment. J. Infect. Dis. 180 (1999) 586-593
    • (1999) J. Infect. Dis. , vol.180 , pp. 586-593
    • Fritz, R.S.1    Hayden, F.G.2    Calfee, D.P.3    Cass, L.4    Peng, A.W.5    Alvord, G.6    Strober, W.7    Straus, S.E.8
  • 22
    • 0005918784 scopus 로고    scopus 로고
    • Gottschalk, A., 1958, Neuraminidase: its substrate and mode of action, in Advances in Enzymology, 20 edn, vol. XX F.F. Nord (Ed.) Interscience Publishers, Inc., London, pp. 135-146.
  • 23
    • 9644262504 scopus 로고    scopus 로고
    • Neuraminidase inhibitor-rimantadine combinations exert additive and synergistic anti-influenza virus effects in MDCK cells
    • Govorkova E.A., Fang H.B., Tan M., and Webster R.G. Neuraminidase inhibitor-rimantadine combinations exert additive and synergistic anti-influenza virus effects in MDCK cells. Antimicrob. Agents Chemother. 48 12 (2004) 4855-4863
    • (2004) Antimicrob. Agents Chemother. , vol.48 , Issue.12 , pp. 4855-4863
    • Govorkova, E.A.1    Fang, H.B.2    Tan, M.3    Webster, R.G.4
  • 24
    • 0031724750 scopus 로고    scopus 로고
    • Evidence for zanamivir resistance in an immunocompromised child infected with influenza B virus
    • Gubareva L.V., Matrosovich M.N., Brenner M.K., Bethell R., and Webster R.G. Evidence for zanamivir resistance in an immunocompromised child infected with influenza B virus. J. Infect. Dis. 178 5 (1998) 1257-1262
    • (1998) J. Infect. Dis. , vol.178 , Issue.5 , pp. 1257-1262
    • Gubareva, L.V.1    Matrosovich, M.N.2    Brenner, M.K.3    Bethell, R.4    Webster, R.G.5
  • 26
    • 33747194939 scopus 로고    scopus 로고
    • Halloran, M. E., Hayden, F. G., Yang, Y., Longini, I. M., & Monto, A. S. 2006, Antiviral effects on influenza viral transmission and pathogenicity: Observations from household-based trials, American Journal of Epidemiology, vol. In press.
  • 27
    • 0002325004 scopus 로고    scopus 로고
    • Amantadine and rimantadine-mechanisms
    • Richman D.D. (Ed), John Wiley & Sons Ltd.
    • Hay A.J. Amantadine and rimantadine-mechanisms. In: Richman D.D. (Ed). Antiviral Drug Resistance (1996), John Wiley & Sons Ltd. 43-58
    • (1996) Antiviral Drug Resistance , pp. 43-58
    • Hay, A.J.1
  • 28
    • 16544394111 scopus 로고    scopus 로고
    • Pandemic influenza-is an antiviral response realistic?
    • Hayden F. Pandemic influenza-is an antiviral response realistic?. Pediatr. Infect. Dis. J. 23 11 (2004) S262-S269
    • (2004) Pediatr. Infect. Dis. J. , vol.23 , Issue.11
    • Hayden, F.1
  • 29
    • 0023030837 scopus 로고
    • Combinations of antiviral agents for treatment of influenza virus infections
    • Hayden F.G. Combinations of antiviral agents for treatment of influenza virus infections. J. Antimicrob. Chemother. 18 Suppl. B (1986) 177-183
    • (1986) J. Antimicrob. Chemother. , vol.18 , Issue.SUPPL. B , pp. 177-183
    • Hayden, F.G.1
  • 30
    • 0035969779 scopus 로고    scopus 로고
    • Perspectives on antiviral use during pandemic influenza
    • Hayden F.G. Perspectives on antiviral use during pandemic influenza. Philos. Trans. R. Soc. Lond. 356 (2001) 1877-1884
    • (2001) Philos. Trans. R. Soc. Lond. , vol.356 , pp. 1877-1884
    • Hayden, F.G.1
  • 31
    • 0022644964 scopus 로고
    • Prevention of natural colds by contact prophylaxis with intranasal alpha 2-interferon
    • Hayden F.G., Albrecht J.K., Kaiser D.L., and Gwaltney J.M.J. Prevention of natural colds by contact prophylaxis with intranasal alpha 2-interferon. N. Engl. J. Med. 314 2 (1986) 71-75
    • (1986) N. Engl. J. Med. , vol.314 , Issue.2 , pp. 71-75
    • Hayden, F.G.1    Albrecht, J.K.2    Kaiser, D.L.3    Gwaltney, J.M.J.4
  • 32
    • 30444452284 scopus 로고    scopus 로고
    • Amantadine, rimantadine and related agents
    • Yu V.L., et al. (Ed), ESun Technologies, LLC, Pittsburgh, PA
    • Hayden F.G., and Aoki F.Y. Amantadine, rimantadine and related agents. In: Yu V.L., et al. (Ed). Antimicrobial Therapy and Vaccines. second ed. vol. 2 (2005), ESun Technologies, LLC, Pittsburgh, PA 705-729
    • (2005) Antimicrobial Therapy and Vaccines. second ed. , vol.2 , pp. 705-729
    • Hayden, F.G.1    Aoki, F.Y.2
  • 33
    • 30444452446 scopus 로고    scopus 로고
    • Influenza neuraminidase inhibitors
    • Yu V.L., et al. (Ed), ESun Technologies, LLC, Pittsburgh, PA
    • Hayden F.G., and Aoki F.Y. Influenza neuraminidase inhibitors. In: Yu V.L., et al. (Ed). Antimicrobial therapy and vaccines. second ed. vol. 2 (2005), ESun Technologies, LLC, Pittsburgh, PA 773-789
    • (2005) Antimicrobial therapy and vaccines. second ed. , vol.2 , pp. 773-789
    • Hayden, F.G.1    Aoki, F.Y.2
  • 34
    • 1142309473 scopus 로고    scopus 로고
    • Management of influenza in households: a prospective, randomized comparison of oseltamivir treatment with or without post-exposure prophylaxis
    • Hayden F.G., Belshe R., Villanueva C., Lanno R., Hughes C., Small I., Dutkowski R., Ward P., and Carr J. Management of influenza in households: a prospective, randomized comparison of oseltamivir treatment with or without post-exposure prophylaxis. J. Infect. Dis. 189 (2004) 440-449
    • (2004) J. Infect. Dis. , vol.189 , pp. 440-449
    • Hayden, F.G.1    Belshe, R.2    Villanueva, C.3    Lanno, R.4    Hughes, C.5    Small, I.6    Dutkowski, R.7    Ward, P.8    Carr, J.9
  • 35
    • 0024819536 scopus 로고
    • Emergence and apparent transmission of rimantadine-resistant influenza A virus in families
    • Hayden F.G., Belshe R.B., Clover R.D., Hay A.J., Oakes M.G., and Soo W. Emergence and apparent transmission of rimantadine-resistant influenza A virus in families. N. Engl. J. Med. 321 25 (1989) 1696-1702
    • (1989) N. Engl. J. Med. , vol.321 , Issue.25 , pp. 1696-1702
    • Hayden, F.G.1    Belshe, R.B.2    Clover, R.D.3    Hay, A.J.4    Oakes, M.G.5    Soo, W.6
  • 36
    • 0019198751 scopus 로고
    • Enhancement of activity against influenza viruses by combinations of antiviral agents
    • Hayden F.G., Douglas R.G.J., and Simons R. Enhancement of activity against influenza viruses by combinations of antiviral agents. Antimicrob. Agents Chemother. 18 4 (1980) 536-541
    • (1980) Antimicrob. Agents Chemother. , vol.18 , Issue.4 , pp. 536-541
    • Hayden, F.G.1    Douglas, R.G.J.2    Simons, R.3
  • 37
    • 0032005791 scopus 로고    scopus 로고
    • Local and systemic cytokine responses during experimental human influenza A virus infection
    • Hayden F.G., Fritz R.S., Lobo M., Alvord G., Strober W., and Straus S.E. Local and systemic cytokine responses during experimental human influenza A virus infection. J. Clin. Invest. 101 3 (1998) 643-649
    • (1998) J. Clin. Invest. , vol.101 , Issue.3 , pp. 643-649
    • Hayden, F.G.1    Fritz, R.S.2    Lobo, M.3    Alvord, G.4    Strober, W.5    Straus, S.E.6
  • 39
  • 40
    • 0020534168 scopus 로고
    • Differences in side effects of amantadine hydrochloride and rimantadine hydrochloride relate to differences in pharmacokinetics
    • Hayden F.G., Hoffman H.E., and Spyker D.A. Differences in side effects of amantadine hydrochloride and rimantadine hydrochloride relate to differences in pharmacokinetics. Antimicrob. Agents Chemother. 23 3 (1983) 458-464
    • (1983) Antimicrob. Agents Chemother. , vol.23 , Issue.3 , pp. 458-464
    • Hayden, F.G.1    Hoffman, H.E.2    Spyker, D.A.3
  • 43
    • 0030032258 scopus 로고    scopus 로고
    • Safety and efficacy of the neuraminidase inhibitor GG167 in experimental human influenza
    • Hayden F.G., Treanor J.J., Betts R.F., Lobo M., Esinhart J.D., and Hussey E.K. Safety and efficacy of the neuraminidase inhibitor GG167 in experimental human influenza. JAMA 275 4 (1996) 295-299
    • (1996) JAMA , vol.275 , Issue.4 , pp. 295-299
    • Hayden, F.G.1    Treanor, J.J.2    Betts, R.F.3    Lobo, M.4    Esinhart, J.D.5    Hussey, E.K.6
  • 45
    • 6944227719 scopus 로고    scopus 로고
    • Influenza viruses resistant to the antiviral drug oseltamivir: transmission studies in ferrets
    • Herlocher M.L., Truscon R., Elias S., Yen H.L., Roberts N.A., Ohmit S.E., and Monto A.S. Influenza viruses resistant to the antiviral drug oseltamivir: transmission studies in ferrets. J. Infect. Dis. 190 9 (2004) 1627-1630
    • (2004) J. Infect. Dis. , vol.190 , Issue.9 , pp. 1627-1630
    • Herlocher, M.L.1    Truscon, R.2    Elias, S.3    Yen, H.L.4    Roberts, N.A.5    Ohmit, S.E.6    Monto, A.S.7
  • 47
    • 84936394783 scopus 로고
    • Absorption of influenza hemagglutinins and virus by red blood cells
    • Hirst G.K. Absorption of influenza hemagglutinins and virus by red blood cells. Journal of Experimental Medicine 76 (1942) 195-209
    • (1942) Journal of Experimental Medicine , vol.76 , pp. 195-209
    • Hirst, G.K.1
  • 50
    • 0034538794 scopus 로고    scopus 로고
    • Management of influenza. Use of new antivirals and resistance in perspective
    • Jackson H.C., Roberts N., Wang Z., and Belshe R. Management of influenza. Use of new antivirals and resistance in perspective. Clin. Drug Invest. 20 6 (2000) 447-454
    • (2000) Clin. Drug Invest. , vol.20 , Issue.6 , pp. 447-454
    • Jackson, H.C.1    Roberts, N.2    Wang, Z.3    Belshe, R.4
  • 51
    • 0034978549 scopus 로고    scopus 로고
    • Symptom pathogenesis during acute influenza: interleukin-6 and other cytokine responses
    • Kaiser L., Fritz R.S., Straus S.E., Gubareva L., and Hayden F.G. Symptom pathogenesis during acute influenza: interleukin-6 and other cytokine responses. J. Med. Virol. 64 (2001) 262-268
    • (2001) J. Med. Virol. , vol.64 , pp. 262-268
    • Kaiser, L.1    Fritz, R.S.2    Straus, S.E.3    Gubareva, L.4    Hayden, F.G.5
  • 52
    • 0034074146 scopus 로고    scopus 로고
    • Short-term treatment with zanamivir to prevent influenza: results of a placebo-controlled study
    • Kaiser L., Henry D., Flack N., Keene O., and Hayden F.G. Short-term treatment with zanamivir to prevent influenza: results of a placebo-controlled study. Clin. Infect. Dis. 30 (2000) 587-589
    • (2000) Clin. Infect. Dis. , vol.30 , pp. 587-589
    • Kaiser, L.1    Henry, D.2    Flack, N.3    Keene, O.4    Hayden, F.G.5
  • 53
    • 0034722755 scopus 로고    scopus 로고
    • Impact of zanamivir on antibiotics use for respiratory events following acute influenza in adolescents and adults
    • Kaiser L., Keene O.N., Hammond J., Elliott M., and Hayden F.G. Impact of zanamivir on antibiotics use for respiratory events following acute influenza in adolescents and adults. Arch. Intern. Med. 160 (2000) 3234-3240
    • (2000) Arch. Intern. Med. , vol.160 , pp. 3234-3240
    • Kaiser, L.1    Keene, O.N.2    Hammond, J.3    Elliott, M.4    Hayden, F.G.5
  • 54
    • 0031048319 scopus 로고    scopus 로고
    • Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity
    • Kim C.U., Lew W., and Williams M.A. Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity. J Am Chem Soc 119 (1997) 681-690
    • (1997) J Am Chem Soc , vol.119 , pp. 681-690
    • Kim, C.U.1    Lew, W.2    Williams, M.A.3
  • 56
    • 0028883441 scopus 로고
    • Prolonged shedding of amantadine-resistant influenzae A viruses by immunodeficient patients: detection by polymerase chain reaction-restriction analysis
    • Klimov A.I., Rocha E., Hayden F.G., Shult P.A., Roumillat L.F., and Cox N.J. Prolonged shedding of amantadine-resistant influenzae A viruses by immunodeficient patients: detection by polymerase chain reaction-restriction analysis. J. Infect. Dis. 172 5 (1995) 1352-1355
    • (1995) J. Infect. Dis. , vol.172 , Issue.5 , pp. 1352-1355
    • Klimov, A.I.1    Rocha, E.2    Hayden, F.G.3    Shult, P.A.4    Roumillat, L.F.5    Cox, N.J.6
  • 57
    • 0014400598 scopus 로고
    • Combined inhibition of influenza virus reproduction in cell culture using interferon and amantadine
    • Lavrov S.V., Eremkina E.I., Orlova T.G., Galegov G.A., Soloviev V.D., and Zhdanov V.M. Combined inhibition of influenza virus reproduction in cell culture using interferon and amantadine. Nature 217 5131 (1968) 856-857
    • (1968) Nature , vol.217 , Issue.5131 , pp. 856-857
    • Lavrov, S.V.1    Eremkina, E.I.2    Orlova, T.G.3    Galegov, G.A.4    Soloviev, V.D.5    Zhdanov, V.M.6
  • 59
    • 0035077692 scopus 로고    scopus 로고
    • Efficacy of zanamivir against avian influenza A viruses that possess genes encoding H5N1 internal proteins and are pathogenic in mammals
    • Leneva I.A., Goloubeva O., Fenton R.J., Tisdale M., and Webster R.G. Efficacy of zanamivir against avian influenza A viruses that possess genes encoding H5N1 internal proteins and are pathogenic in mammals. Antimicrob. Agents Chemother. 45 4 (2001) 1216-1224
    • (2001) Antimicrob. Agents Chemother. , vol.45 , Issue.4 , pp. 1216-1224
    • Leneva, I.A.1    Goloubeva, O.2    Fenton, R.J.3    Tisdale, M.4    Webster, R.G.5
  • 63
    • 7644241814 scopus 로고    scopus 로고
    • Neuraminidase is important for the initiation of influenza virus infection in human airway epithelium
    • Matrosovich M.N., Matrosovich T.Y., Gray T., Roberts N.A., and Klenk H.D. Neuraminidase is important for the initiation of influenza virus infection in human airway epithelium. J. Virol. 78 22 (2004) 12665-12667
    • (2004) J. Virol. , vol.78 , Issue.22 , pp. 12665-12667
    • Matrosovich, M.N.1    Matrosovich, T.Y.2    Gray, T.3    Roberts, N.A.4    Klenk, H.D.5
  • 65
    • 0000183286 scopus 로고
    • 2-deoxy-2,3-dehydroxialic acids I. Syntheses and properties of 2-deoxy, 3dehydro-N-acylneuraminic acids and their methyl esters
    • Meindl P., and Tuppy H. 2-deoxy-2,3-dehydroxialic acids I. Syntheses and properties of 2-deoxy, 3dehydro-N-acylneuraminic acids and their methyl esters. Monatsh. Chem 100 (1969) 1295-2306
    • (1969) Monatsh. Chem , vol.100 , pp. 1295-2306
    • Meindl, P.1    Tuppy, H.2
  • 66
    • 27644439501 scopus 로고    scopus 로고
    • Susceptibilities of antiviral-resistant influenza viruses to novel neuraminidase inhibitors
    • Mishin V.P., Hayden F.G., and Gubareva L.V. Susceptibilities of antiviral-resistant influenza viruses to novel neuraminidase inhibitors. Antimicrob. Agents Chemother. 49 11 (2005) 4515-4520
    • (2005) Antimicrob. Agents Chemother. , vol.49 , Issue.11 , pp. 4515-4520
    • Mishin, V.P.1    Hayden, F.G.2    Gubareva, L.V.3
  • 68
    • 25444501243 scopus 로고    scopus 로고
    • Neuraminidase Inhibitors for Influenza
    • Moscona A. Neuraminidase Inhibitors for Influenza. N. Engl. J. Med. 353 13 (2005) 1363-1373
    • (2005) N. Engl. J. Med. , vol.353 , Issue.13 , pp. 1363-1373
    • Moscona, A.1
  • 69
    • 84921706204 scopus 로고    scopus 로고
    • Use of influenza antivirals during 2003-2004 and monitoring of neuraminidase inhibitor resistance
    • NISN. Use of influenza antivirals during 2003-2004 and monitoring of neuraminidase inhibitor resistance. Wkly. Epidemiol. Rec. 80 17 (2005) 156
    • (2005) Wkly. Epidemiol. Rec. , vol.80 , Issue.17 , pp. 156
    • NISN1
  • 70
    • 0014931976 scopus 로고
    • In vivo selection of an influenza A2 strain resistant to amantadine
    • Oxford J.S., and Logan I.S. In vivo selection of an influenza A2 strain resistant to amantadine. Nature 226 (1970) 82-83
    • (1970) Nature , vol.226 , pp. 82-83
    • Oxford, J.S.1    Logan, I.S.2
  • 72
    • 0017151109 scopus 로고
    • Inhibition of influenza virus replication in tissue culture by 2-deoxy-2,3-dehydro-N-trifluoroacetylneuraminic acid (FANA): mechanism of action
    • Palese P., and Compans R.W. Inhibition of influenza virus replication in tissue culture by 2-deoxy-2,3-dehydro-N-trifluoroacetylneuraminic acid (FANA): mechanism of action. Journal of General Virology 33 1 (1976) 159-163
    • (1976) Journal of General Virology , vol.33 , Issue.1 , pp. 159-163
    • Palese, P.1    Compans, R.W.2
  • 73
    • 0016272701 scopus 로고
    • Characterization of temperature sensitive influenza virus mutants defective in neuraminidase
    • Palese P., Tobita K., Ueda M., and Compans R.W. Characterization of temperature sensitive influenza virus mutants defective in neuraminidase. Virology 61 2 (1974) 397-410
    • (1974) Virology , vol.61 , Issue.2 , pp. 397-410
    • Palese, P.1    Tobita, K.2    Ueda, M.3    Compans, R.W.4
  • 74
    • 0014200862 scopus 로고
    • Amantadine hydrochloride. Analysis of data related to its proposed use for prevention of A2 influenza virus disease in human beings
    • Sabin A.B. Amantadine hydrochloride. Analysis of data related to its proposed use for prevention of A2 influenza virus disease in human beings. JAMA 200 11 (1967) 943-950
    • (1967) JAMA , vol.200 , Issue.11 , pp. 943-950
    • Sabin, A.B.1
  • 75
    • 0018120919 scopus 로고
    • Amantadine and influenza: evaluation of conflicting reports
    • Sabin A.B. Amantadine and influenza: evaluation of conflicting reports. J. Infect. Dis. 138 4 (1978) 557-566
    • (1978) J. Infect. Dis. , vol.138 , Issue.4 , pp. 557-566
    • Sabin, A.B.1
  • 76
    • 0014684012 scopus 로고
    • Amantadine in the treatment of Parkinson's disease
    • Schwab R.S., England A.C.J., Poskanzer D.C., and Young R.R. Amantadine in the treatment of Parkinson's disease. JAMA 19 7 (1969) 1168-1170
    • (1969) JAMA , vol.19 , Issue.7 , pp. 1168-1170
    • Schwab, R.S.1    England, A.C.J.2    Poskanzer, D.C.3    Young, R.R.4
  • 77
  • 78
    • 0031978256 scopus 로고    scopus 로고
    • Emergence of drug resistance during an influenza epidemic: insights from a mathematical model
    • Stilianakis N.I., Perelson A.S., and Hayden F.G. Emergence of drug resistance during an influenza epidemic: insights from a mathematical model. J. Infect. Dis. 177 (1998) 863-873
    • (1998) J. Infect. Dis. , Issue.177 , pp. 863-873
    • Stilianakis, N.I.1    Perelson, A.S.2    Hayden, F.G.3
  • 79
    • 0025983151 scopus 로고
    • Virulence of rimantadine-resistant human influenza A (H3N2) viruses in ferrets
    • Sweet C., Hayden F.G., Jakeman K.J., Grambas S., and Hay A.J. Virulence of rimantadine-resistant human influenza A (H3N2) viruses in ferrets. J. Infect. Dis. 164 5 (1991) 969-972
    • (1991) J. Infect. Dis. , vol.164 , Issue.5 , pp. 969-972
    • Sweet, C.1    Hayden, F.G.2    Jakeman, K.J.3    Grambas, S.4    Hay, A.J.5
  • 80
    • 0013979301 scopus 로고
    • Functional significance of sialidase during influenza virus multiplication
    • Seto J.T., and Rott R. Functional significance of sialidase during influenza virus multiplication. Virology 30 1 (1966) 731-737
    • (1966) Virology , vol.30 , Issue.1 , pp. 731-737
    • Seto, J.T.1    Rott, R.2
  • 82
    • 0026665418 scopus 로고
    • The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor.
    • Varghese J.N., McKimm-Breschkin J.L., Caldwell J.B., Kortt A.A., and Colman P.M. The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor. Proteins 14 3 (1992) 327-332
    • (1992) Proteins , vol.14 , Issue.3 , pp. 327-332
    • Varghese, J.N.1    McKimm-Breschkin, J.L.2    Caldwell, J.B.3    Kortt, A.A.4    Colman, P.M.5
  • 84
    • 25444432780 scopus 로고    scopus 로고
    • Avian influenza A (H5N1) infection in humans
    • The Writing Committee of the World Health Organization (WHO) Consultation on Human Influenza. Avian influenza A (H5N1) infection in humans. N. Engl. J. Med. 353 13 (2005) 1374-1385
    • (2005) N. Engl. J. Med. , vol.353 , Issue.13 , pp. 1374-1385
  • 87
    • 0035054088 scopus 로고    scopus 로고
    • Position statement: global neuraminidase inhibitor susceptibility network
    • Zambon M., and Hayden F.G. Position statement: global neuraminidase inhibitor susceptibility network. Antivir. Res. 49 (2001) 147-156
    • (2001) Antivir. Res. , vol.49 , pp. 147-156
    • Zambon, M.1    Hayden, F.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.