Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching

Journal of Experimental Medicine

Volumn 205, Issue 13, 2008, Pages 3079-3090

  Wang, Jing H ^a,b   Alt, Frederick W ^a,b   Gostissa, Monica ^a,b   Datta, Abhishek ^a,b   Murphy, Michael ^a,b   Alimzhanov, Marat B ^b   Coakley, Kristen M ^a,b   Rajewsky, Klaus ^b   Manis, John P ^b   Yan, Catherine T ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN J CHAIN; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN LAMBDA CHAIN; PROTEIN P53; XRCC4 PROTEIN; DNA BINDING PROTEIN; MYC PROTEIN; MYC PROTEIN, MOUSE; UNCLASSIFIED DRUG; XRCC4 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B CELL LYMPHOMA; B LYMPHOCYTE; CONTROLLED STUDY; DNA REPAIR; DNA STRAND BREAKAGE; FLUORESCENCE ACTIVATED CELL SORTER; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENETIC RECOMBINATION; IMMUNOGLOBULIN VARIABLE REGION; MOLECULAR CLONING; MOUSE; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; ONCOGENE C MYC; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; AMINO ACID SEQUENCE; ANIMAL; CELL TRANSFORMATION; DNA DAMAGE; GENE REARRANGEMENT; GENE TRANSLOCATION; GENETICS; HUMAN; IMMUNOGLOBULIN HEAVY CHAIN GENE; IMMUNOLOGY; LYMPHOMA; MOLECULAR GENETICS; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; ANIMALS; B-LYMPHOCYTES; BASE SEQUENCE; CELL TRANSFORMATION, NEOPLASTIC; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; GENE REARRANGEMENT, B-LYMPHOCYTE; GENES, IMMUNOGLOBULIN HEAVY CHAIN; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN HEAVY CHAINS; LYMPHOMA; LYMPHOMA, B-CELL; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; PROTO-ONCOGENE PROTEINS C-MYC; RECOMBINATION, GENETIC; SEQUENCE ALIGNMENT; TRANSLOCATION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 59649086891     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20082271     Document Type: Article

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