-
1
-
-
0021273420
-
Human epidermal growth factor receptor cDNA Sequence and aberrant expression of the amplified gene in A432 epidermoid carcinoma cells
-
ULLRICH A, COUSSENS L, HAYFLICK JS, DULL TJ, GREY A, TAM AW et al.: Human epidermal growth factor receptor cDNA Sequence and aberrant expression of the amplified gene in A432 epidermoid carcinoma cells. Nature (1984) 309:418-425.
-
(1984)
Nature
, vol.309
, pp. 418-425
-
-
Ullrich, A.1
Coussens, L.2
Hayflick, J.S.3
Dull, T.J.4
Grey, A.5
Tam, A.W.6
-
2
-
-
0031081425
-
Signalling through focal adhesion kinase
-
HANKS SK, POLTE TR: Signalling through focal adhesion kinase. Bioessays (1997) 19:137-145.
-
(1997)
Bioessays
, vol.19
, pp. 137-145
-
-
Hanks, S.K.1
Polte, T.R.2
-
3
-
-
0029257377
-
Signal transduction through integrins: A central role for focal adhesion kinase?
-
RICHARDSON A, PARSONS JT: Signal transduction through integrins: a central role for focal adhesion kinase? Bioessays (1995) 17:229-236.
-
(1995)
Bioessays
, vol.17
, pp. 229-236
-
-
Richardson, A.1
Parsons, J.T.2
-
5
-
-
0027260615
-
Expression of an N-terminally truncated form of human focal adhesion kinase in brain
-
ANDRE E, BECKER-ANDRE M: Expression of an N-terminally truncated form of human focal adhesion kinase in brain. Biochem. Biophys. Res. Commun. (1993) 190:140-147.
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.190
, pp. 140-147
-
-
Andre, E.1
Becker-Andre, M.2
-
6
-
-
0029114247
-
Focal adhesion kinase in the brain: Novel subcellular localization and specific regulation by Fyn tyrosine kinase in mutant mice
-
GRANT SG, KARL KA, KIEBLER MA, KANDEL ER: Focal adhesion kinase in the brain: novel subcellular localization and specific regulation by Fyn tyrosine kinase in mutant mice. Genes Dev. (1995) 9:1909-1921.
-
(1995)
Genes Dev.
, vol.9
, pp. 1909-1921
-
-
Grant, S.G.1
Karl, K.A.2
Kiebler, M.A.3
Kandel, E.R.4
-
7
-
-
0026674919
-
Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin
-
HANKS SK, CALALB MB, HARPER MC, PATEL SK: Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin. Proc. Natl. Acad. Sci. USA (1992) 89:8487-8491.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 8487-8491
-
-
Hanks, S.K.1
Calalb, M.B.2
Harper, M.C.3
Patel, S.K.4
-
8
-
-
0026612521
-
pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions
-
SCHALLER MD, BORGMAN CA, COBB BS, VINES RR, REYNOLDS AB, PARSONS JT: pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions. Proc. Natl. Acad. Sci. USA (1992) 89:5192-5196.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 5192-5196
-
-
Schaller, M.D.1
Borgman, C.A.2
Cobb, B.S.3
Vines, R.R.4
Reynolds, A.B.5
Parsons, J.T.6
-
9
-
-
0034666146
-
Role of Grb7 targeting to focal contacts and its phosphorylation by focal adhesion kinase in regulation of cell migration
-
HAN DC, SHEN TL, GUAN JL: Role of Grb7 targeting to focal contacts and its phosphorylation by focal adhesion kinase in regulation of cell migration. J. Biol. Chem. (2000) 275:28911-28917.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 28911-28917
-
-
Han, D.C.1
Shen, T.L.2
Guan, J.L.3
-
10
-
-
0035800777
-
The cytoskeletal/non-muscle isoform of α-actinin is phosphorylated on its actin-binding domain by the focal adhesion kinase
-
IZAGUIRRE G, AGUIRRE L, HU YP et al.: The cytoskeletal/non-muscle isoform of α-actinin is phosphorylated on its actin-binding domain by the focal adhesion kinase. J. Biol. Chem. (2001) 276:28676-28685.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 28676-28685
-
-
Izaguirre, G.1
Aguirre, L.2
Hu, Y.P.3
-
11
-
-
0031044781
-
Focal adhesion kinase: At the crossroads of signal transduction
-
ILIC D, DAMSKY CH, YAMAMOTO T: Focal adhesion kinase: at the crossroads of signal transduction. J. Cell Sci. (1997) 110:401-407.
-
(1997)
J. Cell Sci.
, vol.110
, pp. 401-407
-
-
Ilic, D.1
Damsky, C.H.2
Yamamoto, T.3
-
12
-
-
0028877919
-
Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: A role for Src family kinases
-
CALALB MB, POLTE TR, HANKS SK: Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases. Mol. Cell. Biol. (1995) 15:954-963.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 954-963
-
-
Calalb, M.B.1
Polte, T.R.2
Hanks, S.K.3
-
14
-
-
0029955660
-
An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase
-
HILDEBRAND JD, TAYLOR JM, PARSONS JT: An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase. Mol. Cell. Biol. (1996) 16:3169-3178.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 3169-3178
-
-
Hildebrand, J.D.1
Taylor, J.M.2
Parsons, J.T.3
-
15
-
-
0027938974
-
Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase
-
CHEN H, GUAN J: Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase. Proc. Natl. Acad. Sci. USA (1994) 91:10148-10152.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 10148-10152
-
-
Chen, H.1
Guan, J.2
-
16
-
-
0028609382
-
Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
-
SCHLAEPFER DD, HANKS SK, HUNTER T, VAN DER GEER P: Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature (1994) 372:786-791.
-
(1994)
Nature
, vol.372
, pp. 786-791
-
-
Schlaepfer, D.D.1
Hanks, S.K.2
Hunter, T.3
Van Der Geer, P.4
-
17
-
-
0029150292
-
Focal adhesion kinase and paxillin bind to peptides mimicking β integrin cytoplasmic domains
-
SCHALLER MD, OTEY CA, HILDEBRAND JD, PARSONS JT: Focal adhesion kinase and paxillin bind to peptides mimicking β integrin cytoplasmic domains.J. Cell Biol. (1995) 130:1181-1187.
-
(1995)
J. Cell Biol.
, vol.130
, pp. 1181-1187
-
-
Schaller, M.D.1
Otey, C.A.2
Hildebrand, J.D.3
Parsons, J.T.4
-
19
-
-
0031683065
-
The FERM domain: A unique module involved in the linkage of cytoplasmic proteins to the membrane
-
CHISHTI A, KIM A, MARFATIA S et al.: The FERM domain: a unique module involved in the linkage of cytoplasmic proteins to the membrane. Trends Biochem. Sci. (1998) 23:281-282.
-
(1998)
Trends Biochem. Sci.
, vol.23
, pp. 281-282
-
-
Chishti, A.1
Kim, A.2
Marfatia, S.3
-
21
-
-
0033962672
-
Focal adhesions - The cytoskeletal connection
-
CRITCHLEY DR: Focal adhesions - the cytoskeletal connection. Curr. Opin. Cell Biol. (2000) 12:133-139.
-
(2000)
Curr. Opin. Cell Biol.
, vol.12
, pp. 133-139
-
-
Critchley, D.R.1
-
22
-
-
0032940071
-
ERM proteins in cell adhesion and membrane dynamics
-
MANGEAT P, ROY C, MARTIN M: ERM proteins in cell adhesion and membrane dynamics. Trends Cell Biol. (1999) 9:187-192.
-
(1999)
Trends Cell Biol.
, vol.9
, pp. 187-192
-
-
Mangeat, P.1
Roy, C.2
Martin, M.3
-
24
-
-
0027428367
-
Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions
-
HILDEBRAND JD, SCHALLER MD, PARSONS JT: Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions. J. Cell Biol. (1993) 123:993-1005.
-
(1993)
J. Cell Biol.
, vol.123
, pp. 993-1005
-
-
Hildebrand, J.D.1
Schaller, M.D.2
Parsons, J.T.3
-
25
-
-
0035176458
-
Serine phosphorylation of focal adhesion kinase in interphase and mitosis: A possible role in modulating binding to p130(Cas)
-
MA A, RICHARDSON A, SCHAEFER EM, PARSONS JT: Serine phosphorylation of focal adhesion kinase in interphase and mitosis: a possible role in modulating binding to p130(Cas). Mol. Biol. Cell (2001) 12:1-12.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 1-12
-
-
Ma, A.1
Richardson, A.2
Schaefer, E.M.3
Parsons, J.T.4
-
26
-
-
0033601745
-
Dissociation of FAK/p130(CAS)/c-Src complex during mitosis: Role of mitosis-specific serine phosphorylation of FAK
-
YAMAKITA Y, TOTSUKAWA G, YAMASHIRO S et al.: Dissociation of FAK/p130(CAS)/c-Src complex during mitosis: role of mitosis-specific serine phosphorylation of FAK. J. Cell Biol. (1999) 144:315-324.
-
(1999)
J. Cell Biol.
, vol.144
, pp. 315-324
-
-
Yamakita, Y.1
Totsukawa, G.2
Yamashiro, S.3
-
27
-
-
0033575287
-
PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway
-
TAMURA M, GU J, DANEN EH, TAKINO T, MIYAMOTO S, YAMADA KM: PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway. J. Biol. Chem. (1999) 274:20693-20703.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 20693-20703
-
-
Tamura, M.1
Gu, J.2
Danen, E.H.3
Takino, T.4
Miyamoto, S.5
Yamada, K.M.6
-
28
-
-
0032486198
-
Inhibition of cell migration, spreading and focal adhesions by tumour suppressor PTEN
-
TAMURA M, GU J, MATSUMOTO K, AOTA S, PARSONS R, YAMADA KM: Inhibition of cell migration, spreading and focal adhesions by tumour suppressor PTEN. Science (1998) 280:1614-1617.
-
(1998)
Science
, vol.280
, pp. 1614-1617
-
-
Tamura, M.1
Gu, J.2
Matsumoto, K.3
Aota, S.4
Parsons, R.5
Yamada, K.M.6
-
29
-
-
0027439594
-
Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAK
-
SCHALLER MD, BORGMAN CA, PARSONS JT: Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAK. Mol. Cell. Biol. (1993) 13:785-791.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 785-791
-
-
Schaller, M.D.1
Borgman, C.A.2
Parsons, J.T.3
-
30
-
-
0032784060
-
Regulated expression of focal adhesion kinase-related nonkinase, the autonomously expressed C-terminal domain of focal adhesion kinase
-
NOLAN K, LACOSTE J, PARSONS JT: Regulated expression of focal adhesion kinase-related nonkinase, the autonomously expressed C-terminal domain of focal adhesion kinase. Mol. Cell. Biol. (1999) 19:6120-6129.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 6120-6129
-
-
Nolan, K.1
Lacoste, J.2
Parsons, J.T.3
-
31
-
-
0035137373
-
Selective expression of an endogenous inhibitor of FAK regulates proliferation and migration of vascular smooth muscle cells
-
TAYLOR JM, MACK CP, NOLAN K, REGAN CP, OWENS GK, PARSONS JT: Selective expression of an endogenous inhibitor of FAK regulates proliferation and migration of vascular smooth muscle cells. Mol. Cell. Biol. (2001) 21:1565-1572.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 1565-1572
-
-
Taylor, J.M.1
Mack, C.P.2
Nolan, K.3
Regan, C.P.4
Owens, G.K.5
Parsons, J.T.6
-
32
-
-
0029120440
-
Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice
-
ILIC D, FURUTA Y, KANAZAWA S, TAKEDA N, SOBUE K, NAKATSUJI N et al.: Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature (1995) 377:539-544.
-
(1995)
Nature
, vol.377
, pp. 539-544
-
-
Ilic, D.1
Furuta, Y.2
Kanazawa, S.3
Takeda, N.4
Sobue, K.5
Nakatsuji, N.6
-
33
-
-
0029971297
-
A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAK
-
RICHARDSON A, PARSONS T: A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAK. Nature (1996) 380:538-540.
-
(1996)
Nature
, vol.380
, pp. 538-540
-
-
Richardson, A.1
Parsons, T.2
-
34
-
-
0032472411
-
The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility
-
FINCHAM VJ, FRAME MC: The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility. EMBO J. (1998) 17:81-92.
-
(1998)
EMBO J.
, vol.17
, pp. 81-92
-
-
Fincham, V.J.1
Frame, M.C.2
-
35
-
-
0028988989
-
v-Src-induced degradation of focal adhesion kinase during morphological transformation of chicken embryo fibroblasts
-
FINCHAM VJ, WYKE JA, FRAME MC: v-Src-induced degradation of focal adhesion kinase during morphological transformation of chicken embryo fibroblasts. Oncogene (1995) 10:2247-2252.
-
(1995)
Oncogene
, vol.10
, pp. 2247-2252
-
-
Fincham, V.J.1
Wyke, J.A.2
Frame, M.C.3
-
36
-
-
0034725624
-
v-Src induces tyrosine phosphorylation of focal adhesion kinase independently of tyrosine 397 and formation of a complex with Src
-
MCLEAN GW, FINCHAM VJ, FRAME MC: v-Src induces tyrosine phosphorylation of focal adhesion kinase independently of tyrosine 397 and formation of a complex with Src. J. Biol. Chem. (2000) 275:23333-23339.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23333-23339
-
-
Mclean, G.W.1
Fincham, V.J.2
Frame, M.C.3
-
37
-
-
0029948080
-
Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn
-
CARY LA, CHANG JF, GUAN JL: Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn. J. Cell Sci. (1996) 109:1787-1794.
-
(1996)
J. Cell Sci.
, vol.109
, pp. 1787-1794
-
-
Cary, L.A.1
Chang, J.F.2
Guan, J.L.3
-
38
-
-
0029092674
-
Focal adhesion kinase (p125FAK) expression correlates with motility of human melanoma cell lines
-
AKASAKA T, VAN LEEUWEN RL, YOSHINAGA IG, MIHM MC Jr, BYERS HR: Focal adhesion kinase (p125FAK) expression correlates with motility of human melanoma cell lines. J. Invest. Dermatol. (1995) 105:104-108.
-
(1995)
J. Invest. Dermatol.
, vol.105
, pp. 104-108
-
-
Akasaka, T.1
Vanleeuwen, R.L.2
Yoshinaga, I.G.3
Mihm M.C., Jr.4
Byers, H.R.5
-
39
-
-
0034693854
-
Focal adhesion kinase: A regulator of focal adhesion dynamics and cell movement
-
PARSONS JT, MARTIN KH, SLACK JK, TAYLOR JM, WEED SA: Focal adhesion kinase: a regulator of focal adhesion dynamics and cell movement. Oncogene (2000) 19:5606-5613.
-
(2000)
Oncogene
, vol.19
, pp. 5606-5613
-
-
Parsons, J.T.1
Martin, K.H.2
Slack, J.K.3
Taylor, J.M.4
Weed, S.A.5
-
40
-
-
0034532347
-
p125 focal adhesion kinase promotes malignant astrocytoma cell proliferation in vivo
-
WANG D, GRAMMER JR, COBBS CS, STEWART JE Jr, LIU Z, RHODEN R, HECKER TP, DING Q, GLADSON CL: p125 focal adhesion kinase promotes malignant astrocytoma cell proliferation in vivo. J. Cell Sci. (2000) 113:4221-4230.
-
(2000)
J. Cell Sci.
, vol.113
, pp. 4221-4230
-
-
Wang, D.1
Grammer, J.R.2
Cobbs, C.S.3
Stewart J.E., Jr.4
Liu, Z.5
Rhoden, R.6
Hecker, T.P.7
Ding, Q.8
Gladson, C.L.9
-
41
-
-
0036048217
-
Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling
-
AVIZIENYTE E, WYKE AW, JONES RJ, MCLEAN GW, WESTHOFF MA, BRUNTON VG, FRAME MC: Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling. Nat. Cell Biol. (2002) 4:632-638.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 632-638
-
-
Avizienyte, E.1
Wyke, A.W.2
Jones, R.J.3
Mclean, G.W.4
Westhoff, M.A.5
Brunton, V.G.6
Frame, M.C.7
-
42
-
-
0028018234
-
Potential role for focal adhesion kinase in migrating and proliferating keratinocytes near epidermal wounds and in culture
-
GATES RE, KING LE Jr, HANKS SK, NANNEY LB: Potential role for focal adhesion kinase in migrating and proliferating keratinocytes near epidermal wounds and in culture. Cell Growth Differ. (1994) 5:891-899.
-
(1994)
Cell Growth Differ.
, vol.5
, pp. 891-899
-
-
Gates, R.E.1
King L.E., Jr.2
Hanks, S.K.3
Nanney, L.B.4
-
43
-
-
0029739950
-
Control of adhesion-dependent cell survival by focal adhesion kinase
-
FRISCH SM, VUORI K, RUOSLAHTI E, CHAN-HUI PY: Control of adhesion-dependent cell survival by focal adhesion kinase. J. Cell Biol. (1996) 134:793-799.
-
(1996)
J. Cell Biol.
, vol.134
, pp. 793-799
-
-
Frisch, S.M.1
Vuori, K.2
Ruoslahti, E.3
Chan-Hui, P.Y.4
-
44
-
-
0033578641
-
Suppression of ultraviolet irradiation-induced apoptosis by overexpression of focal adhesion kinase in Madin-Darby canine kidney cells
-
CHAN PC, LAI JF, CHENG CH, TANG MJ, CHIU CC, CHEN HC: Suppression of ultraviolet irradiation-induced apoptosis by overexpression of focal adhesion kinase in Madin-Darby canine kidney cells. J. Biol. Chem. (1999) 274:26901-26906.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 26901-26906
-
-
Chan, P.C.1
Lai, J.F.2
Cheng, C.H.3
Tang, M.J.4
Chiu, C.C.5
Chen, H.C.6
-
45
-
-
0037064030
-
Dual inhibition of focal adhesion kinase (FAK) and epidermal growth factor receptor (EGFR) pathways cooperatively induces death receptor- mediated apoptosis in human breast cancer cells
-
GOLUBOVSKAYA V, BEVIGLIA L, XU LH, EARP HS, CRAVEN R, CANCE W: Dual inhibition of focal adhesion kinase (FAK) and epidermal growth factor receptor (EGFR) pathways cooperatively induces death receptor- mediated apoptosis in human breast cancer cells. J. Biol. Chem. (2002) 277:38978-38987.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 38978-38987
-
-
Golubovskaya, V.1
Beviglia, L.2
Xu, L.H.3
Earp, H.S.4
Craven, R.5
Cance, W.6
-
46
-
-
0032932248
-
Activating SRC mutation in a subset of advanced human colon cancers
-
IRBY RB, MAO W, COPPOLA D et al.: Activating SRC mutation in a subset of advanced human colon cancers. Nat. Genet. (1999) 21:187-190.
-
(1999)
Nat. Genet.
, vol.21
, pp. 187-190
-
-
Irby, R.B.1
Mao, W.2
Coppola, D.3
-
47
-
-
0034213931
-
RTK mutations and human syndromes: When good receptors turn bad
-
ROBERTSON SC, TYNAN J, DONOGHUE DJ: RTK mutations and human syndromes: when good receptors turn bad. Trends Genet. (2000) 16:368-369.
-
(2000)
Trends Genet.
, vol.16
, pp. 368-369
-
-
Robertson, S.C.1
Tynan, J.2
Donoghue, D.J.3
-
48
-
-
0033533746
-
Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells
-
AGOCHIYA M, BRUNTON VG, OWENS DW et al.: Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells. Oncogene (1999) 18:5646-5653.
-
(1999)
Oncogene
, vol.18
, pp. 5646-5653
-
-
Agochiya, M.1
Brunton, V.G.2
Owens, D.W.3
-
49
-
-
0031025529
-
A role for epidermal growth factor receptor, c-Src and focal adhesion kinase in an in vitro model for the progression of colon cancer
-
BRUNTON VG, OZANNE BW, PARASKEVA C, FRAME MC: A role for epidermal growth factor receptor, c-Src and focal adhesion kinase in an in vitro model for the progression of colon cancer. Oncogene (1997) 14:283-293.
-
(1997)
Oncogene
, vol.14
, pp. 283-293
-
-
Brunton, V.G.1
Ozanne, B.W.2
Paraskeva, C.3
Frame, M.C.4
-
50
-
-
0030767420
-
Activation of the focal adhesion kinase signal transduction pathway in cervical carcinoma cell lines and human genital epithelial cells immortalized with human papillomavirus Type 18
-
MCCORMACK SJ, BRAZINSKI SE, MOORE JL Jr, WERNESS BA, GOLDSTEIN DJ: Activation of the focal adhesion kinase signal transduction pathway in cervical carcinoma cell lines and human genital epithelial cells immortalized with human papillomavirus Type 18. Oncogene (1997) 15:265-274.
-
(1997)
Oncogene
, vol.15
, pp. 265-274
-
-
Mccormack, S.J.1
Brazinski, S.E.2
Moore J.L., Jr.3
Werness, B.A.4
Goldstein, D.J.5
-
51
-
-
0029795243
-
Focal adhesion kinase (pp125FAK) expression, activation and association with paxillin and p50CSK in human metastatic prostate carcinoma
-
TREMBLAY L, HAUCK W, APRIKIAN AG, BEGIN LR, CHAPDELAINE A, CHEVALIER S: Focal adhesion kinase (pp125FAK) expression, activation and association with paxillin and p50CSK in human metastatic prostate carcinoma. Int. J. Cancer (1996) 68:164-171.
-
(1996)
Int. J. Cancer
, vol.68
, pp. 164-171
-
-
Tremblay, L.1
Hauck, W.2
Aprikian, A.G.3
Begin, L.R.4
Chapdelaine, A.5
Chevalier, S.6
-
52
-
-
0029039421
-
Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumours
-
OWENS LV, XU L, CRAVEN RJ, DENT GA et al.: Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumours. Cancer Res. (1995) 55:2752-2755.
-
(1995)
Cancer Res.
, vol.55
, pp. 2752-2755
-
-
Owens, L.V.1
Xu, L.2
Craven, R.J.3
Dent, G.A.4
-
53
-
-
0031750715
-
Focal adhesion kinase expression in oral cancers
-
KORNBERG LJ: Focal adhesion kinase expression in oral cancers. Head Neck (1998) 20:634-639.
-
(1998)
Head Neck
, vol.20
, pp. 634-639
-
-
Kornberg, L.J.1
-
54
-
-
0029690892
-
Focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer
-
OWENS LV, XU L, DENT GA, YANG X et al.: Focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer. Ann. Surg. Oncol. (1996) 3:100-105.
-
(1996)
Ann. Surg. Oncol.
, vol.3
, pp. 100-105
-
-
Owens, L.V.1
Xu, L.2
Dent, G.A.3
Yang, X.4
-
55
-
-
0033570076
-
Overexpression of focal adhesion kinase, a protein tyrosine kinase, in ovarian carcinoma
-
JUDSON PL, HE X, CANCE WG, VAN LE L: Overexpression of focal adhesion kinase, a protein tyrosine kinase, in ovarian carcinoma. Cancer (1999) 86:1551-1556.
-
(1999)
Cancer
, vol.86
, pp. 1551-1556
-
-
Judson, P.L.1
He, X.2
Cance, W.G.3
Van Le, L.4
-
56
-
-
0031657454
-
Focal adhesion kinase and its potential involvement in tumour invasion and metastasis
-
KORNBERG LJ: Focal adhesion kinase and its potential involvement in tumour invasion and metastasis. Head Neck (1998) 20:745-752.
-
(1998)
Head Neck
, vol.20
, pp. 745-752
-
-
Kornberg, L.J.1
-
57
-
-
0035476836
-
Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signalling promoting the migration of invasive human carcinoma cells
-
HAUCK CR, SIEG DJ, HSIA DA et al.: Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signalling promoting the migration of invasive human carcinoma cells. Cancer Res. (2001) 61:7079-7090.
-
(2001)
Cancer Res.
, vol.61
, pp. 7079-7090
-
-
Hauck, C.R.1
Sieg, D.J.2
Hsia, D.A.3
-
59
-
-
0037011055
-
FRNK blocks v-Src stimulated invasion and experimental metastases without effects on cell motility or growth
-
(In press)
-
HAUCK CR, HSIA DA, PUENTE XS et al.: FRNK blocks v-Src stimulated invasion and experimental metastases without effects on cell motility or growth. EMBO Journal:(In press).
-
EMBO Journal
-
-
Hauck, C.R.1
Hsia, D.A.2
Puente, X.S.3
-
60
-
-
0036001167
-
The focal adhesion kinase - A regulator of cell migration and invasion
-
HAUCK CR, HSIA DA, SCHLAEPFER DD: The focal adhesion kinase - a regulator of cell migration and invasion. IUBMB Life (2002) 53:115-119.
-
(2002)
IUBMB Life
, vol.53
, pp. 115-119
-
-
Hauck, C.R.1
Hsia, D.A.2
Schlaepfer, D.D.3
-
61
-
-
0032031062
-
Both focal adhesion kinase and c-Ras are required for the enhanced matrix metalloproteinase 9 secretion by fibronectin in ovarian cancer cells
-
SHIBATA K, KIKKAWA F, NAWA A et al.: Both focal adhesion kinase and c-Ras are required for the enhanced matrix metalloproteinase 9 secretion by fibronectin in ovarian cancer cells. Cancer Res. (1998) 58:900-903.
-
(1998)
Cancer Res.
, vol.58
, pp. 900-903
-
-
Shibata, K.1
Kikkawa, F.2
Nawa, A.3
-
62
-
-
0035577279
-
Decreased focal adhesion kinase suppresses papilloma formation during experimental mouse skin carcinogenesis
-
MCLEAN GW, BROWN K, ARBUCKLE MI et al.: Decreased focal adhesion kinase suppresses papilloma formation during experimental mouse skin carcinogenesis. Cancer Res. (2001) 61:8385-8389.
-
(2001)
Cancer Res.
, vol.61
, pp. 8385-8389
-
-
Mclean, G.W.1
Brown, K.2
Arbuckle, M.I.3
-
64
-
-
0036164882
-
Signal transduction driving technology driving signal transduction: Factors in the design of targeted therapies
-
GOLEMIS EA, OCHS MF, PUGACHEVA EN: Signal transduction driving technology driving signal transduction: factors in the design of targeted therapies. J. Cell. Biochem. Suppl. (2001) Suppl. 37:42-52.
-
(2001)
J. Cell. Biochem. Suppl.
, Issue.SUPPL. 37
, pp. 42-52
-
-
Golemis, E.A.1
Ochs, M.F.2
Pugacheva, E.N.3
-
65
-
-
0035912062
-
UCS15A, a non-kinase inhibitor of Src signal transduction
-
SHARMA SV, ONEYAMA C, YAMASHITA Y et al.: UCS15A, a non-kinase inhibitor of Src signal transduction. Oncogene (2001) 20:2068-2079.
-
(2001)
Oncogene
, vol.20
, pp. 2068-2079
-
-
Sharma, S.V.1
Oneyama, C.2
Yamashita, Y.3
-
66
-
-
0037150229
-
UCS15A, a novel small molecule, SH3 domain-mediated protein-protein interaction blocking drug
-
ONEYAMA C, NAKANO H, SHARMA SV: UCS15A, a novel small molecule, SH3 domain-mediated protein-protein interaction blocking drug. Oncogene (2002) 21:2037-2050.
-
(2002)
Oncogene
, vol.21
, pp. 2037-2050
-
-
Oneyama, C.1
Nakano, H.2
Sharma, S.V.3
-
67
-
-
0032820782
-
Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration
-
SIEG DJ, HAUCK CR, SCHLAEPFER DD: Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration J. Cell Sci. (1999) 112:2677-2691.
-
(1999)
J. Cell Sci.
, vol.112
, pp. 2677-2691
-
-
Sieg, D.J.1
Hauck, C.R.2
Schlaepfer, D.D.3
-
68
-
-
0035018353
-
Epidermal growth factor-induced tumour cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase
-
LU Z, JIANG G, BLUME-JENSENP, HUNTER T: Epidermal growth factor-induced tumour cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase. Mol. Cell. Biol. (2001) 21:4016-4031.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 4016-4031
-
-
Lu, Z.1
Jiang, G.2
Blume-Jensenp, A.3
Hunter, T.4
-
69
-
-
0037030464
-
The focal adhesion kinase (P125FAK) is constitutively active in human malignant melanoma
-
KAHANA O, MICKSCHE M, WITZ IP, YRON I: The focal adhesion kinase (P125FAK) is constitutively active in human malignant melanoma. Oncogene (2002) 21:3969-3977.
-
(2002)
Oncogene
, vol.21
, pp. 3969-3977
-
-
Kahana, O.1
Micksche, M.2
Witz, I.P.3
Yron, I.4
-
70
-
-
0032964123
-
Alterations in focal adhesion kinase activity and associated proteins during malignant conversion of mouse keratinocytes
-
NEWELL SW, PERCHELLET JP, PERCHELLET EM, ULUG ET: Alterations in focal adhesion kinase activity and associated proteins during malignant conversion of mouse keratinocytes. Mol. Carcinog. (1999) 25:73-83.
-
(1999)
Mol. Carcinog.
, vol.25
, pp. 73-83
-
-
Newell, S.W.1
Perchellet, J.P.2
Perchellet, E.M.3
Ulug, E.T.4
-
71
-
-
0033061032
-
Protein tyrosine kinase inhibitors as novel therapeutic agents
-
LEVITZKI A: Protein tyrosine kinase inhibitors as novel therapeutic agents. Pharmacol. Ther. (1999) 82:231-239.
-
(1999)
Pharmacol. Ther.
, vol.82
, pp. 231-239
-
-
Levitzki, A.1
-
72
-
-
0034043977
-
Site-directed irreversible inhibitors of the erbB family of receptor tyrosine kinases as novel chemotherapeutic agents for cancer
-
FRY DW: Site-directed irreversible inhibitors of the erbB family of receptor tyrosine kinases as novel chemotherapeutic agents for cancer. Anti-Cancer Drug Des. (2000) 15:3-16.
-
(2000)
Anti-Cancer Drug Des.
, vol.15
, pp. 3-16
-
-
Fry, D.W.1
-
73
-
-
0034722893
-
From oncogene to drug: Development of small molecule tyrosine kinase inhibitors as antitumour and antiangiogenic agents
-
MORIN MJ: From oncogene to drug: development of small molecule tyrosine kinase inhibitors as antitumour and antiangiogenic agents. Oncogene (2000) 19:6574-6583.
-
(2000)
Oncogene
, vol.19
, pp. 6574-6583
-
-
Morin, M.J.1
-
74
-
-
0035095455
-
Chronic myeloid leukaemia. STI 571 magnifies the therapeutic dilemma
-
MUGHAL TI, GOLDMAN JM: Chronic myeloid leukaemia. STI 571 magnifies the therapeutic dilemma. Eur. J. Cancer (2001) 37:561-568.
-
(2001)
Eur. J. Cancer
, vol.37
, pp. 561-568
-
-
Mughal, T.I.1
Goldman, J.M.2
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