Hepatitis C virus NS5B polymerase exhibits distinct nucleotide requirements for initiation and elongation

Journal of Biological Chemistry

Volumn 283, Issue 49, 2008, Pages 33893-33901

  Ferrari, Eric ^a   He, Zhiqing ^a   Palermo, Robert E ^a,b   Huang, H C ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTRIC FIELD EFFECTS; ELONGATION; ENZYMES; HYPERSONIC AERODYNAMICS; NUCLEOTIDES; POLYMERS; RNA;

DE NOVO SYNTHESIS; HEPATITIS C VIRUS NS5B POLYMERASES; HIGH CONCENTRATIONS; IN VITRO; NUCLEOSIDE TRIPHOSPHATES; PRIMER EXTENSIONS; RNA GENOMES; RNA POLYMERASES; RNA SYNTHESIS; TEMPLATE SIZES; TRINUCLEOTIDES;

NUCLEIC ACIDS;

NUCLEOSIDE TRIPHOSPHATE; RNA DIRECTED RNA POLYMERASE; ZALCITABINE;

ARTICLE; CATALYSIS; ENZYME ACTIVITY; HEPATITIS C; HEPATITIS C VIRUS; NONHUMAN; PRIORITY JOURNAL; RNA SYNTHESIS; TRANSCRIPTION INITIATION; VIRUS GENOME; VIRUS REPLICATION;

ADENOSINE TRIPHOSPHATE; BASE SEQUENCE; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, VIRAL; HEPACIVIRUS; HEPARIN; KINETICS; MOLECULAR SEQUENCE DATA; NUCLEOTIDES; RECOMBINANT PROTEINS; RIBONUCLEASE T1; RNA; RNA REPLICASE; VIRAL NONSTRUCTURAL PROTEINS; ZALCITABINE;

HEPATITIS C VIRUS;

EID: 57749092998     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M803094200     Document Type: Article

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