Biochemical and pre-steady-state kinetic characterization of the hepatitis C virus RNA polymerase (NS5BΔ21, HC-J4)

Biochemistry

Volumn 45, Issue 11, 2006, Pages 3610-3619

  Cramer, Janina ^a   Jaeger, Joachim ^b   Restle, Tobias ^c  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^b WADSWORTH CENTER   (United States)

^c UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GENES; LIGHT SCATTERING; MONOMERS; NUCLEIC ACIDS; OLIGOMERS; RNA; VIRUSES;

BINDING MECHANISM; ENZYMATIC ACTIVITIES; MONOVALENT SALT; RNA TEMPLATES;

ENZYMES;

ADENOSINE TRIPHOSPHATE; NUCLEOTIDE; PROTEIN NS5B; RNA DIRECTED RNA POLYMERASE; RNA POLYMERASE; UNCLASSIFIED DRUG; VIRUS RNA;

ARTICLE; COMPLEX FORMATION; DIFFUSION; DISSOCIATION CONSTANT; ENZYME ACTIVITY; ENZYME BINDING; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SUBSTRATE; FLUORESCENCE; HEPATITIS C VIRUS; NONHUMAN; NUCLEOTIDE SEQUENCE; OLIGOMERIZATION; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RNA BINDING; RNA SYNTHESIS; STEADY STATE; TITRIMETRY;

BINDING SITES; CONSENSUS SEQUENCE; HEPACIVIRUS; KINETICS; MODELS, BIOLOGICAL; NUCLEOTIDES; PROTEIN BINDING; RNA; RNA REPLICASE; TIME FACTORS;

HEPATITIS C VIRUS; RNA VIRUSES;

EID: 33645238735     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051483s     Document Type: Article

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