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Volumn 249, Issue 1, 1998, Pages 108-118

Biochemical and kinetic analyses of NS5B RNA-dependent RNA polymerase of the hepatitis C virus

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYTIDINE TRIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HYBRID PROTEIN; MAGNESIUM; MANGANESE; NUCLEOSIDE TRIPHOSPHATE; POTASSIUM CHLORIDE; RIBONUCLEOSIDE DERIVATIVE; RNA DIRECTED RNA POLYMERASE; SODIUM CHLORIDE; URIDINE TRIPHOSPHATE; VIRUS ENZYME;

EID: 0032530621     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1998.9311     Document Type: Article
Times cited : (131)

References (34)
  • 2
    • 0030862814 scopus 로고    scopus 로고
    • Molecular targets in inhibition of hepatitis C virus replication
    • Bartenschlager R. Molecular targets in inhibition of hepatitis C virus replication. Antiviral Chem. Chemother. 8:1997;281-301.
    • (1997) Antiviral Chem. Chemother. , vol.8 , pp. 281-301
    • Bartenschlager, R.1
  • 3
    • 0028820118 scopus 로고
    • Complex formation between the NS3 serine-type proteinase of the hepatitis C virus and NS4A and its importance for polyprotein maturation
    • Bartenschlager R., Lohmann V., Wilkinson T., Koch J. O. Complex formation between the NS3 serine-type proteinase of the hepatitis C virus and NS4A and its importance for polyprotein maturation. J. Virol. 69:1995;7519-7528.
    • (1995) J. Virol. , vol.69 , pp. 7519-7528
    • Bartenschlager, R.1    Lohmann, V.2    Wilkinson, T.3    Koch, J.O.4
  • 4
    • 0030051777 scopus 로고    scopus 로고
    • Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus
    • Behrens S.-E., Tomei L., De Francesco R. Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus. EMBO J. 15:1996;12-22.
    • (1996) EMBO J. , vol.15 , pp. 12-22
    • Behrens, S.-E.1    Tomei, L.2    De Francesco, R.3
  • 6
    • 0024509701 scopus 로고
    • Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
    • Choo Q. L., Kuo G., Weiner A. J., Overby L. R., Bradley D. W., Houghton M. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science. 244:1989;359-362.
    • (1989) Science , vol.244 , pp. 359-362
    • Choo, Q.L.1    Kuo, G.2    Weiner, A.J.3    Overby, L.R.4    Bradley, D.W.5    Houghton, M.6
  • 7
    • 0030778811 scopus 로고    scopus 로고
    • Molecular virology of hepatitis C virus
    • Clarke B. Molecular virology of hepatitis C virus. J. Gen. Virol. 78:1997;2397-2410.
    • (1997) J. Gen. Virol. , vol.78 , pp. 2397-2410
    • Clarke, B.1
  • 9
    • 0025328822 scopus 로고
    • Phospholipid biosynthesis and poliovirus genome replication, two coupled phenomena
    • Guinea R., Carrasco L. Phospholipid biosynthesis and poliovirus genome replication, two coupled phenomena. EMBO J. 9:1990;2011-2016.
    • (1990) EMBO J. , vol.9 , pp. 2011-2016
    • Guinea, R.1    Carrasco, L.2
  • 10
    • 0031571638 scopus 로고    scopus 로고
    • Structure of the RNA-dependent RNA polymerase of poliovirus
    • Hansen J. L., Long A. M., Schultz S. C. Structure of the RNA-dependent RNA polymerase of poliovirus. Structure. 5:1997;1109-1122.
    • (1997) Structure , vol.5 , pp. 1109-1122
    • Hansen, J.L.1    Long, A.M.2    Schultz, S.C.3
  • 12
    • 0000361013 scopus 로고    scopus 로고
    • Hepatitis C viruses
    • et al, 1058, Lippincott-Raven, Philadelphia
    • Houghton, M. 1996, Hepatitis C viruses, In, Virology, et al, 1035, 1058, Lippincott-Raven, Philadelphia.
    • (1996) In, Virology , pp. 1035
    • Houghton, M.1
  • 13
    • 0031579246 scopus 로고    scopus 로고
    • Hepatitis C virus NS5B protein is a membrane-associated phosphoprotein with a predominantly perinuclear localization
    • Hwang S. B., Park K.-J., Kim Y.-S., Sung Y. C., Lai M. M. C. Hepatitis C virus NS5B protein is a membrane-associated phosphoprotein with a predominantly perinuclear localization. Virology. 227:1997;439-446.
    • (1997) Virology , vol.227 , pp. 439-446
    • Hwang, S.B.1    Park, K.-J.2    Kim, Y.-S.3    Sung, Y.C.4    Lai, M.M.C.5
  • 14
    • 0028893538 scopus 로고
    • Mutation of the aspartic acid residues of the GDD sequence motif of poliovirus RNA-dependent RNA polymerase results in enzymes with altered metal ion requirements for activity
    • Jablonski S. A., Morrow C. D. Mutation of the aspartic acid residues of the GDD sequence motif of poliovirus RNA-dependent RNA polymerase results in enzymes with altered metal ion requirements for activity. J. Virol. 69:1995;1532-1539.
    • (1995) J. Virol. , vol.69 , pp. 1532-1539
    • Jablonski, S.A.1    Morrow, C.D.2
  • 15
    • 0028881713 scopus 로고
    • Polymerase structures and function: Variations on a theme
    • Joyce C. M., Steitz T. A. Polymerase structures and function: variations on a theme. J. Bacteriol. 177:1995;6321-6329.
    • (1995) J. Bacteriol. , vol.177 , pp. 6321-6329
    • Joyce, C.M.1    Steitz, T.A.2
  • 16
    • 0029938477 scopus 로고    scopus 로고
    • Identification of a highly conserved sequence element at the 3′ terminus of hepatitis C virus genome RNA
    • Kolykhalov A. A., Feinstone S. M., Rice C. M. Identification of a highly conserved sequence element at the 3′ terminus of hepatitis C virus genome RNA. J. Virol. 70:1996;3363-3371.
    • (1996) J. Virol. , vol.70 , pp. 3363-3371
    • Kolykhalov, A.A.1    Feinstone, S.M.2    Rice, C.M.3
  • 18
    • 1842289764 scopus 로고    scopus 로고
    • Biochemical properties of hepatitis C virus NS5B RNA-dependent RNA polymerase and identification of amino acid sequence motifs essential for enzymatic activity
    • Lohmann V., Körner F., Herian U., Bartenschlager R. Biochemical properties of hepatitis C virus NS5B RNA-dependent RNA polymerase and identification of amino acid sequence motifs essential for enzymatic activity. J. Virol. 71:1997;8416-8428.
    • (1997) J. Virol. , vol.71 , pp. 8416-8428
    • Lohmann, V.1    Körner, F.2    Herian, U.3    Bartenschlager, R.4
  • 19
    • 0021970469 scopus 로고
    • Purification of a soluble template-dependent rhinovirus RNA polymerase and its dependence on a host cell protein for viral RNA synthesis
    • Morrow C. D., Lubinski J., Hocko J., Gibbons G. F., Dasgupta A. Purification of a soluble template-dependent rhinovirus RNA polymerase and its dependence on a host cell protein for viral RNA synthesis. J. Virol. 53:1985;266-272.
    • (1985) J. Virol. , vol.53 , pp. 266-272
    • Morrow, C.D.1    Lubinski, J.2    Hocko, J.3    Gibbons, G.F.4    Dasgupta, A.5
  • 21
    • 0026325741 scopus 로고
    • Purification, characterization, and comparison of poliovirus RNA polymerase from native and recombinant sources
    • Neufeld K. L., Richards O. C., Ehrenfeld E. Purification, characterization, and comparison of poliovirus RNA polymerase from native and recombinant sources. J. Biol. Chem. 266:1991;24212-24219.
    • (1991) J. Biol. Chem. , vol.266 , pp. 24212-24219
    • Neufeld, K.L.1    Richards, O.C.2    Ehrenfeld, E.3
  • 22
    • 0029330222 scopus 로고
    • Functional oligomerization of poliovirus RNA-dependent RNA polymerase
    • Pata J. D., Schultz S. C., Kirkegaard K. Functional oligomerization of poliovirus RNA-dependent RNA polymerase. RNA. 1:1995;466-477.
    • (1995) RNA , vol.1 , pp. 466-477
    • Pata, J.D.1    Schultz, S.C.2    Kirkegaard, K.3
  • 24
    • 0017613512 scopus 로고
    • A simplification of the protein assay method of Lowry et al. which is more generally applicable
    • Peterson G. L. A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal. Biochem. 83:1977;346-356.
    • (1977) Anal. Biochem. , vol.83 , pp. 346-356
    • Peterson, G.L.1
  • 25
    • 0024495371 scopus 로고
    • Purification and properties of poliovirus RNA polymerase expressed inEscherichia coli
    • Plotch S. J., Palant O., Gluzman Y. Purification and properties of poliovirus RNA polymerase expressed inEscherichia coli. J. Virol. 63:1989;216-225.
    • (1989) J. Virol. , vol.63 , pp. 216-225
    • Plotch, S.J.1    Palant, O.2    Gluzman, Y.3
  • 26
    • 0001424128 scopus 로고    scopus 로고
    • Flaviviridae: The viruses and their replication
    • B. N.Knipe, P. M.Howley, P. M. et al., Lippincott-Raven, Philadelphia
    • Rice, C. M. 1996, Flaviviridae: The viruses and their replication, In, Virology, Fields, B. N.Knipe, P. M.Howley, P. M. et al., 931, 959, Lippincott-Raven, Philadelphia.
    • (1996) In, Virology, Fields , vol.931 , pp. 959
    • Rice, C.M.1
  • 27
    • 0026783262 scopus 로고
    • Expression, purification, and properties of recombinant encephalomyocarditis virus RNA-dependent RNA polymerase
    • Sankar S., Porter A. G. Expression, purification, and properties of recombinant encephalomyocarditis virus RNA-dependent RNA polymerase. J. Biol. Chem. 267:1992;10168-10176.
    • (1992) J. Biol. Chem. , vol.267 , pp. 10168-10176
    • Sankar, S.1    Porter, A.G.2
  • 31
    • 0028831056 scopus 로고
    • Hepatitis C virus-encoded nonstructural protein NS4A has versatile functions in viral protein processing
    • Tanji Y., Hijikata M., Satoh S., Kaneko T., Shimotohno K. Hepatitis C virus-encoded nonstructural protein NS4A has versatile functions in viral protein processing. J. Virol. 69:1995;1575-1581.
    • (1995) J. Virol. , vol.69 , pp. 1575-1581
    • Tanji, Y.1    Hijikata, M.2    Satoh, S.3    Kaneko, T.4    Shimotohno, K.5
  • 32
    • 0019964841 scopus 로고
    • Poliovirus RNA-dependent RNA polymerase synthesizes full-length copies of poliovirion RNA, cellular mRNA, and several plant virus RNAs in vitro
    • Tuschall D. M., Hiebert E., Flanegan J. B. Poliovirus RNA-dependent RNA polymerase synthesizes full-length copies of poliovirion RNA, cellular mRNA, and several plant virus RNAs in vitro. J. Virol. 44:1982;209-216.
    • (1982) J. Virol. , vol.44 , pp. 209-216
    • Tuschall, D.M.1    Hiebert, E.2    Flanegan, J.B.3
  • 33
    • 0019951369 scopus 로고
    • Genome-length copies of poliovirion RNA are synthesized in vitro by the poliovirus RNA-dependent RNA polymerase
    • Van Dyke T. A., Rickles R. J., Flanegan J. B. Genome-length copies of poliovirion RNA are synthesized in vitro by the poliovirus RNA-dependent RNA polymerase. J. Biol. Chem. 257:1982;4610-4617.
    • (1982) J. Biol. Chem. , vol.257 , pp. 4610-4617
    • Van Dyke, T.A.1    Rickles, R.J.2    Flanegan, J.B.3


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