메뉴 건너뛰기




Volumn 15, Issue 1, 1996, Pages 12-22

Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus

Author keywords

HCV; NS5B; RNA replication; RNA dependent RNA polymerase; Terminal nucleotidyl transferase

Indexed keywords

PRIMER DNA; PRIMER RNA; RNA DIRECTED RNA POLYMERASE; VIRUS ENZYME; VIRUS RNA;

EID: 0030051777     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00329.x     Document Type: Article
Times cited : (656)

References (53)
  • 1
    • 0027287798 scopus 로고
    • Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions
    • Bartenschlager, R., Ahlborn-Laake, L., Mous, J. and Jacobsen, H. (1993) Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions. J. Virol., 67, 3835-3844.
    • (1993) J. Virol. , vol.67 , pp. 3835-3844
    • Bartenschlager, R.1    Ahlborn-Laake, L.2    Mous, J.3    Jacobsen, H.4
  • 2
    • 0021099156 scopus 로고
    • Terminal adenylation in the synthesis of RNA by Qβ replicase
    • Bausch, J.N., Russell, F., Miele, E.A., Dobkin, C. and Mill, D. (1983) Terminal adenylation in the synthesis of RNA by Qβ replicase. J. Biol. Chem., 258, 1978-1984.
    • (1983) J. Biol. Chem. , vol.258 , pp. 1978-1984
    • Bausch, J.N.1    Russell, F.2    Miele, E.A.3    Dobkin, C.4    Mill, D.5
  • 3
    • 0027317542 scopus 로고
    • The 60 kDa protein of HeLa 17S U2 snRNPs is immunologically related to the yeast PRP9 protein and required for mRNA splicing in vitro
    • Behrens, S.E., Galisson, F., Legrain, P. and Lührmann, R. (1993) The 60 kDa protein of HeLa 17S U2 snRNPs is immunologically related to the yeast PRP9 protein and required for mRNA splicing in vitro. Proc. Natl Acad. Sci USA, 90, 8229-8233.
    • (1993) Proc. Natl Acad. Sci USA , vol.90 , pp. 8229-8233
    • Behrens, S.E.1    Galisson, F.2    Legrain, P.3    Lührmann, R.4
  • 4
    • 0018370008 scopus 로고
    • RNA replication: Function and structure of Qβ-replicase
    • Blumenthal, T. and Carmichael, G.G. (1979) RNA replication: function and structure of Qβ-replicase. Annu. Rev. Biochem., 48, 525-548.
    • (1979) Annu. Rev. Biochem. , vol.48 , pp. 525-548
    • Blumenthal, T.1    Carmichael, G.G.2
  • 5
    • 0028233381 scopus 로고
    • RNA template-directed RNA synthesis by T7 RNA polymerase
    • Cazenave, C. and Uhlenbeck, O.C. (1994) RNA template-directed RNA synthesis by T7 RNA polymerase. Proc. Natl Acad. Sci. USA, 91, 6972-6976.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 6972-6976
    • Cazenave, C.1    Uhlenbeck, O.C.2
  • 7
    • 0024509701 scopus 로고
    • Isolation of a cDNA clone derived from a blood-borne non-A non-B viral hepatitis genome
    • Choo, Q.-L., Kuo, G , Weiner, A.J., Overby, L.R., Bradley, D.W. and Houghton, M. (1989) Isolation of a cDNA clone derived from a blood-borne non-A non-B viral hepatitis genome. Science, 244, 359-362.
    • (1989) Science , vol.244 , pp. 359-362
    • Choo, Q.-L.1    Kuo, G.2    Weiner, A.J.3    Overby, L.R.4    Bradley, D.W.5    Houghton, M.6
  • 8
    • 0025968921 scopus 로고
    • Genetic organization and diversity of the hepatitis C virus
    • Choo, Q.I. et al (1991) Genetic organization and diversity of the hepatitis C virus. Proc. Natl Acad. Sci. USA, 88, 2451-2455.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 2451-2455
    • Choo, Q.I.1
  • 10
  • 11
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam, J.D., Lebovitz, R M. and Roeder, R.G. (1983) Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res., 11, 1475-1489.
    • (1983) Nucleic Acids Res. , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 13
    • 0027414062 scopus 로고
    • Characterization of the hepatitis C virus-encoded serine proteinase: Determination of proteinase-dependent polyprotein cleavage sites
    • Grakoui, A., McCourt, D.W., Wychowski, C., Feinstone, S.M. and Rice, C.M (1993a) Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites. J. Virol., 67, 2832-2843.
    • (1993) J. Virol. , vol.67 , pp. 2832-2843
    • Grakoui, A.1    McCourt, D.W.2    Wychowski, C.3    Feinstone, S.M.4    Rice, C.M.5
  • 15
    • 0027476809 scopus 로고
    • Expression and identification of hepatitis C virus polyprotein cleavage products
    • Grakoui, A., Wychowski, C., Lin, C., Feinstone, S.M. and Rice, C.M. (1993c) Expression and identification of hepatitis C virus polyprotein cleavage products. J. Virol., 67, 1385-1395.
    • (1993) J. Virol. , vol.67 , pp. 1385-1395
    • Grakoui, A.1    Wychowski, C.2    Lin, C.3    Feinstone, S.M.4    Rice, C.M.5
  • 16
    • 0023031091 scopus 로고
    • Characterization of West Nile virus RNA dependent RNA polymerase and cellular terminal adenylyl and uridylyl transferases in cell-free extracts
    • Grun, B.G. and Brinton, A.B. (1986) Characterization of West Nile virus RNA dependent RNA polymerase and cellular terminal adenylyl and uridylyl transferases in cell-free extracts. J. Virol., 60, 1113-1124.
    • (1986) J. Virol. , vol.60 , pp. 1113-1124
    • Grun, B.G.1    Brinton, A.B.2
  • 17
    • 0002273955 scopus 로고
    • Analysis of replication complexes of positive strand RNA plant viruses
    • Davison, A.J. and Elliott, R.M. (eds). IRL Press, Oxford. UK
    • Hayes, R.J. and Buck, K.W. (1993) Analysis of replication complexes of positive strand RNA plant viruses. In Davison, A.J. and Elliott, R.M. (eds). Molecular Virology: A Practical Approach. IRL Press, Oxford. UK, pp. 1-34.
    • (1993) Molecular Virology: A Practical Approach , pp. 1-34
    • Hayes, R.J.1    Buck, K.W.2
  • 18
    • 0022458866 scopus 로고
    • Synthesis of plus- and minus-strand RNA from poliovirion RNA template in vitro
    • Hey, T.D., Richards, O C and Ehrenfeld, E. (1986) Synthesis of plus- and minus-strand RNA from poliovirion RNA template in vitro. J. Virol., 58, 790-796.
    • (1986) J. Virol. , vol.58 , pp. 790-796
    • Hey, T.D.1    Richards, O.C.2    Ehrenfeld, E.3
  • 19
    • 0023138141 scopus 로고
    • Host factor-induced template modification during synthesis of poliovirus RNA in vitro
    • Hey, T.D., Richards, O.C. and Ehrenfeld, E. (1987) Host factor-induced template modification during synthesis of poliovirus RNA in vitro. J. Virol. 61, 802-811.
    • (1987) J. Virol. , vol.61 , pp. 802-811
    • Hey, T.D.1    Richards, O.C.2    Ehrenfeld, E.3
  • 20
    • 0027163740 scopus 로고
    • Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus
    • Hijikata, M., Mizushima, H., Akagi, T., Mori, S., Kakiuchi, N , Kato, N., Tanaka, T., Kimura, K. and Shimotohno, K. (1993) Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus. J. Virol , 67, 4665-1675.
    • (1993) J. Virol , vol.67 , pp. 4665-11675
    • Hijikata, M.1    Mizushima, H.2    Akagi, T.3    Mori, S.4    Kakiuchi, N.5    Kato, N.6    Tanaka, T.7    Kimura, K.8    Shimotohno, K.9
  • 22
    • 0024564099 scopus 로고
    • Replication of RNA by the DNA-dependent RNA polymerase of phage T7
    • Konarska, M. and Sharp, P.A. (1989) Replication of RNA by the DNA-dependent RNA polymerase of phage T7. Cell. 57, 423-431.
    • (1989) Cell , vol.57 , pp. 423-431
    • Konarska, M.1    Sharp, P.A.2
  • 23
    • 0027504136 scopus 로고
    • Evolution and taxonomy of positive-strand RNA viruses: Implications of comparative analysis of amino acid sequences
    • Koonin, E.V. and Dolja, V.V. (1993) Evolution and taxonomy of positive-strand RNA viruses: implications of comparative analysis of amino acid sequences. Crit. Rev. Biochem. Mol. Biol., 28, 375-430.
    • (1993) Crit. Rev. Biochem. Mol. Biol. , vol.28 , pp. 375-430
    • Koonin, E.V.1    Dolja, V.V.2
  • 24
    • 0024511734 scopus 로고
    • An assay for circulating antibodies to a major etiologic virus of human non-A non-B hepatitis
    • Kuo, G. et al. (1989) An assay for circulating antibodies to a major etiologic virus of human non-A non-B hepatitis. Science, 244, 362-364.
    • (1989) Science , vol.244 , pp. 362-364
    • Kuo, G.1
  • 26
    • 0022517957 scopus 로고
    • Mechanism of in vitro synthesis of covalently linked dimeric RNA molecules by the poliovirus replicase
    • Lubinski, J.M., Kaplan, G., Racaniello, V.R. and Dasgupta, A. (1986) Mechanism of in vitro synthesis of covalently linked dimeric RNA molecules by the poliovirus replicase. J. Virol., 58, 459-467.
    • (1986) J. Virol. , vol.58 , pp. 459-467
    • Lubinski, J.M.1    Kaplan, G.2    Racaniello, V.R.3    Dasgupta, A.4
  • 27
    • 0000407708 scopus 로고
    • The molecular biology of hepatitis C virus
    • Matsuura, Y. and Myamura, T. (1993) The molecular biology of hepatitis C virus. Semin. Virol., 4, 297-304.
    • (1993) Semin. Virol. , vol.4 , pp. 297-304
    • Matsuura, Y.1    Myamura, T.2
  • 28
    • 0026337299 scopus 로고
    • Characterization of a cofactor that regulates dimerization of a mammalian homeodomam protein
    • Mendel, D.B., Khavari, P.A., Conley, P.B., Graves, M.K., Hansen, L.P., Admon, A. and Crabtree, G.R. (1991) Characterization of a cofactor that regulates dimerization of a mammalian homeodomam protein. Science, 254, 1762-1767.
    • (1991) Science , vol.254 , pp. 1762-1767
    • Mendel, D.B.1    Khavari, P.A.2    Conley, P.B.3    Graves, M.K.4    Hansen, L.P.5    Admon, A.6    Crabtree, G.R.7
  • 29
    • 0025249362 scopus 로고
    • Hepatitis C virus shares amino acid sequence similarity with pestivirus and flavivirus as well as members of two plant virus supergroups
    • Miller, R.H. and Purcell, R.H. (1990) Hepatitis C virus shares amino acid sequence similarity with pestivirus and flavivirus as well as members of two plant virus supergroups. Proc. Natl Acad Sci. USA, 87, 2057-2061.
    • (1990) Proc. Natl Acad Sci. USA , vol.87 , pp. 2057-2061
    • Miller, R.H.1    Purcell, R.H.2
  • 30
    • 0028225961 scopus 로고
    • Significance of the immune response to a major, conformational B-eell epitope on the hepatitis C virus NS3 region defined by a human monoclonal antibody
    • Mondelli, M.U., Cerino, A., Boender, P, Oudshoorn, P., Middeldorp, J , Fipaldini, C., La Monica, N. and Habets, W. (1994) Significance of the immune response to a major, conformational B-eell epitope on the hepatitis C virus NS3 region defined by a human monoclonal antibody. J Virol., 68, 4829-4836.
    • (1994) J Virol. , vol.68 , pp. 4829-4836
    • Mondelli, M.U.1    Cerino, A.2    Boender, P.3    Oudshoorn, P.4    Middeldorp, J.5    Fipaldini, C.6    La Monica, N.7    Habets, W.8
  • 31
    • 0026506654 scopus 로고
    • Detection of intrahepatic replication of hepatitis C virus RNA by in situ hybridization and comparison with histopathology
    • Negro, F., Pacchioni, D., Shimizu, Y., Miller, R.H., Bussolati, G., Purcell, R.H. and Bonino, F. (1992) Detection of intrahepatic replication of hepatitis C virus RNA by in situ hybridization and comparison with histopathology. Proc. Natl Acad. Sci. USA, 89, 2247-2251.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 2247-2251
    • Negro, F.1    Pacchioni, D.2    Shimizu, Y.3    Miller, R.H.4    Bussolati, G.5    Purcell, R.H.6    Bonino, F.7
  • 32
    • 0026325741 scopus 로고
    • Purification, characterization, and comparison of poliovirus RNA polymerase from native and recombinant sources
    • Neufeld, K.L., Richards, O.C. and Ehrenfeld, E. (1991) Purification, characterization, and comparison of poliovirus RNA polymerase from native and recombinant sources. J. Biol. Chem., 266, 24212-24219.
    • (1991) J. Biol. Chem. , vol.266 , pp. 24212-24219
    • Neufeld, K.L.1    Richards, O.C.2    Ehrenfeld, E.3
  • 35
    • 0024495371 scopus 로고
    • Purification and properties of poliovirus RNA polymerase expressed in Escherichia coli
    • Plotch, S.J., Palant, O and Gluzman, Y. (1989) Purification and properties of poliovirus RNA polymerase expressed in Escherichia coli. J. Virol , 63, 216-225.
    • (1989) J. Virol , vol.63 , pp. 216-225
    • Plotch, S.J.1    Palant, O.2    Gluzman, Y.3
  • 36
    • 0024784519 scopus 로고
    • Identification of four conserved motifs among the RNA dependent polymerase encoding elements
    • Poch, O., Sauvaget, I., Delarue, M. and Tordo, N. (1989) Identification of four conserved motifs among the RNA dependent polymerase encoding elements. EMBO J., 8, 3867-3874.
    • (1989) EMBO J. , vol.8 , pp. 3867-3874
    • Poch, O.1    Sauvaget, I.2    Delarue, M.3    Tordo, N.4
  • 37
    • 0027422866 scopus 로고
    • Picornavirus nonstructural proteins emerging roles in virus replication and inhibition of host cell functions
    • Porter, A.G. (1993) Picornavirus nonstructural proteins emerging roles in virus replication and inhibition of host cell functions. J. Virol. 67, 6917-6921.
    • (1993) J. Virol. , vol.67 , pp. 6917-6921
    • Porter, A.G.1
  • 38
    • 0025166005 scopus 로고
    • Hepatitis C virus infection is associated with the development of hepatocellular carcinoma
    • Saito, I. et al (1990) Hepatitis C virus infection is associated with the development of hepatocellular carcinoma. Proc. Natl Acad. Sci. USA, 87, 6547-6549.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 6547-6549
    • Saito, I.1
  • 41
    • 0019335619 scopus 로고
    • Palindrome-like dimers of double-stranded RNA of encephalomyocardttis virus
    • Senkevich, T.G., Cumakov, I.M., Lipskajya, G.Y. and Agol, V.I. (1980) Palindrome-like dimers of double-stranded RNA of encephalomyocardttis virus. Virology, 102, 339-348.
    • (1980) Virology , vol.102 , pp. 339-348
    • Senkevich, T.G.1    Cumakov, I.M.2    Lipskajya, G.Y.3    Agol, V.I.4
  • 43
    • 0000357058 scopus 로고
    • Hepatocellular carcinoma in Japan and its linkage to infection with hepatitis C virus
    • Shimotohno, K. (1993) Hepatocellular carcinoma in Japan and its linkage to infection with hepatitis C virus. Semin. Virol., 4, 305-312.
    • (1993) Semin. Virol. , vol.4 , pp. 305-312
    • Shimotohno, K.1
  • 45
    • 0001935242 scopus 로고
    • Structure and replication of the alphavirus genome
    • Schlesinger, S S. and Schlesinger, M.J. (eds), Plenum Press, New York
    • Strauss, E G. and Strauss, J.H. (1986) Structure and replication of the alphavirus genome. In Schlesinger, S S. and Schlesinger, M.J. (eds), The Togaviridae and Flaviviridae. Plenum Press, New York, pp. 35-90.
    • (1986) The Togaviridae and Flaviviridae , pp. 35-90
    • Strauss, E.G.1    Strauss, J.H.2
  • 46
    • 0023042283 scopus 로고
    • Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes
    • Studier, F.W. and Moffatt, B.A. (1986) Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes. J. Mol. Biol., 189, 113-130.
    • (1986) J. Mol. Biol. , vol.189 , pp. 113-130
    • Studier, F.W.1    Moffatt, B.A.2
  • 47
    • 0026084948 scopus 로고
    • Structure and organization of the hepatitis C virus genome isolated from human carriers
    • Takamizawa, A. et al. (1991) Structure and organization of the hepatitis C virus genome isolated from human carriers. J. Virol., 65, 1105-1113.
    • (1991) J. Virol. , vol.65 , pp. 1105-1113
    • Takamizawa, A.1
  • 48
    • 0027176287 scopus 로고
    • NS3 is a serine protease required for processing of hepatitis C virus polyprotein
    • Tomei, L., Failla, C., Santolini, E., De Francesco, R. and La Monica, N. (1993) NS3 is a serine protease required for processing of hepatitis C virus polyprotein. J. Virol., 67, 4017-4026.
    • (1993) J. Virol. , vol.67 , pp. 4017-4026
    • Tomei, L.1    Failla, C.2    Santolini, E.3    De Francesco, R.4    La Monica, N.5
  • 49
    • 0019964841 scopus 로고
    • Poliovirus RNA-dependent RNA polymerase synthesizes full-length copies of poltovirus RNA, cellular mRNA, and several plant virus RNAs in vitro
    • Tuschall, D.M., Hiebert, E. and Flanegan, J.B. (1982) Poliovirus RNA-dependent RNA polymerase synthesizes full-length copies of poltovirus RNA, cellular mRNA, and several plant virus RNAs in vitro. J Virol., 44, 209-216.
    • (1982) J Virol. , vol.44 , pp. 209-216
    • Tuschall, D.M.1    Hiebert, E.2    Flanegan, J.B.3
  • 51
    • 0028961384 scopus 로고
    • Transfection of a differentiated human hepatoma cell line (Huh7) with in vitro transcribed hepatitis C virus (HCV) RNA and establishment of a long-term culture persistently infected with HCV
    • Yoo, B.J. et al. (1995) Transfection of a differentiated human hepatoma cell line (Huh7) with in vitro transcribed hepatitis C virus (HCV) RNA and establishment of a long-term culture persistently infected with HCV. J. Virol., 69, 32-38.
    • (1995) J. Virol. , vol.69 , pp. 32-38
    • Yoo, B.J.1
  • 52
    • 0021798221 scopus 로고
    • Poliovirus RNA-dependent RNA polymerase and host cell protein synthesize product RNA twice the size of poliovirion RNA in vitro
    • Young, D.C., Tuschall, D.M. and Flanegan, J.B. (1985) Poliovirus RNA-dependent RNA polymerase and host cell protein synthesize product RNA twice the size of poliovirion RNA in vitro. J. Virol., 54, 256-264
    • (1985) J. Virol. , vol.54 , pp. 256-264
    • Young, D.C.1    Tuschall, D.M.2    Flanegan, J.B.3
  • 53
    • 0019878050 scopus 로고
    • Terminal uridylyl transferase of Vigna unguiculata: Purification and characterization of an enzyme catalyzing the addition of a single UMP residue to the 3′-end of an RNA primer
    • Zabel, P.L., Dossers, K.W. and van Kammen, A. (1981) Terminal uridylyl transferase of Vigna unguiculata: purification and characterization of an enzyme catalyzing the addition of a single UMP residue to the 3′-end of an RNA primer. Nucleic Acids Res., 9, 2433-2453.
    • (1981) Nucleic Acids Res. , vol.9 , pp. 2433-2453
    • Zabel, P.L.1    Dossers, K.W.2    Van Kammen, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.