메뉴 건너뛰기




Volumn 8, Issue 12, 2008, Pages 1897-1920

FOXP3+ regulatory T cells as biomarkers in human malignancies

Author keywords

Biomarker; Cancer; Forkhead box P3; FOXP3; Tumour immunity; Tumour infiltrating lymphocytes

Indexed keywords

MESSENGER RNA; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; TRANSCRIPTION FACTOR FOXP3; TUMOR MARKER;

EID: 57649152965     PISSN: 14712598     EISSN: None     Source Type: Journal    
DOI: 10.1517/14712590802494022     Document Type: Review
Times cited : (23)

References (143)
  • 1
    • 33751231701 scopus 로고    scopus 로고
    • + regulatory T cells: Current controversies and future perspectives
    • + regulatory T cells: Current controversies and future perspectives. Eur J Immunol 2006; 36:2832-6
    • (2006) Eur J Immunol , vol.36 , pp. 2832-2836
    • Banham, A.H.1    Powrie, F.M.2    Suri-Payer, E.3
  • 2
    • 40849086381 scopus 로고    scopus 로고
    • Immunoregulatory T cells: Role and potential as a target in malignancy
    • Beyer M, Schultze JL. Immunoregulatory T cells: role and potential as a target in malignancy. Curr Oncol Rep 2008;10:130-6
    • (2008) Curr Oncol Rep , vol.10 , pp. 130-136
    • Beyer, M.1    Schultze, J.L.2
  • 3
    • 44749092510 scopus 로고    scopus 로고
    • Curiel TJ. Regulatory T cells and treatment of cancer. Curr Opin Immunol 2008;20:241-6
    • Curiel TJ. Regulatory T cells and treatment of cancer. Curr Opin Immunol 2008;20:241-6
  • 4
    • 37849026029 scopus 로고    scopus 로고
    • Regulatory T cells and tumour immunity - observations in mice and men
    • Gallimore AM, Godkin AJ. Regulatory T cells and tumour immunity - observations in mice and men. Immunology 2008;123:157-63
    • (2008) Immunology , vol.123 , pp. 157-163
    • Gallimore, A.M.1    Godkin, A.J.2
  • 5
    • 44849100619 scopus 로고    scopus 로고
    • Is FOXP3 a bona fide marker for human regulatory T cells?
    • Roncarolo MG, Gregori S. Is FOXP3 a bona fide marker for human regulatory T cells? Eur J Immunol 2008;38:925-7
    • (2008) Eur J Immunol , vol.38 , pp. 925-927
    • Roncarolo, M.G.1    Gregori, S.2
  • 7
    • 39049171753 scopus 로고    scopus 로고
    • Comprehensive analysis of FOXP3 mRNA expression in leukemia and transformed cell lines
    • Yamamoto M, Tsuji-Takayama K, Suzuki M, et al. Comprehensive analysis of FOXP3 mRNA expression in leukemia and transformed cell lines. Leuk Res 2008;32:651-8
    • (2008) Leuk Res , vol.32 , pp. 651-658
    • Yamamoto, M.1    Tsuji-Takayama, K.2    Suzuki, M.3
  • 8
    • 33746351318 scopus 로고    scopus 로고
    • Making regulatory T cells with defined antigen specificity: Role in autoimmunity and cancer
    • Kretschmer K, Apostolou I, Jaeckel E, et al. Making regulatory T cells with defined antigen specificity: role in autoimmunity and cancer. Immunol Rev 2006;212:163-9
    • (2006) Immunol Rev , vol.212 , pp. 163-169
    • Kretschmer, K.1    Apostolou, I.2    Jaeckel, E.3
  • 12
    • 33846980131 scopus 로고    scopus 로고
    • Epigenetic control of the foxp3 locus in regulatory T cells
    • 30 January doi:10.1371/journal.pbio.0050038
    • Floess S, Freyer J, Siewert C, et al. Epigenetic control of the foxp3 locus in regulatory T cells. PLoS Biol 2007;5:e38 published online 30 January 2007 doi:10.1371/journal.pbio.0050038
    • (2007) PLoS Biol 2007;5:e38 published online
    • Floess, S.1    Freyer, J.2    Siewert, C.3
  • 13
    • 0034716925 scopus 로고    scopus 로고
    • T cells: Key controllers of immunologic self-tolerance
    • Sakaguchi S. Regulatory T cells: key controllers of immunologic self-tolerance. Cell 2000;101:455-8
    • (2000) Cell , vol.101 , pp. 455-458
    • Regulatory, S.S.1
  • 15
    • 0042591396 scopus 로고    scopus 로고
    • Multiple domains define the expression and regulatory properties of Foxp1 forkhead transcriptional repressors
    • Wang B, Lin D, Li C, et al. Multiple domains define the expression and regulatory properties of Foxp1 forkhead transcriptional repressors. J Biol Chem 2003;278:24259-68
    • (2003) J Biol Chem , vol.278 , pp. 24259-24268
    • Wang, B.1    Lin, D.2    Li, C.3
  • 16
    • 0034526617 scopus 로고    scopus 로고
    • JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome
    • Chatila TA, Blaeser F, Ho N, et al. JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J Clin Invest 2000;106:R75-81
    • (2000) J Clin Invest , vol.106
    • Chatila, T.A.1    Blaeser, F.2    Ho, N.3
  • 17
    • 0035167967 scopus 로고    scopus 로고
    • Bennett CL, Christie J, Ramsdell F, et al. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat Genet 2001;27:20-1
    • Bennett CL, Christie J, Ramsdell F, et al. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat Genet 2001;27:20-1
  • 18
    • 0035162560 scopus 로고    scopus 로고
    • Disruption of a new forkhead/ winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
    • Brunkow ME, Jeffery EW, Hjerrild KA, et al. Disruption of a new forkhead/ winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat Genet 2001;27:68-73
    • (2001) Nat Genet , vol.27 , pp. 68-73
    • Brunkow, M.E.1    Jeffery, E.W.2    Hjerrild, K.A.3
  • 19
    • 0035163909 scopus 로고    scopus 로고
    • X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
    • Wildin RS, Ramsdell F, Peake J, et al. X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat Genet 2001;27:18-20
    • (2001) Nat Genet , vol.27 , pp. 18-20
    • Wildin, R.S.1    Ramsdell, F.2    Peake, J.3
  • 22
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003;299:1057-61
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 24
    • 15244354286 scopus 로고    scopus 로고
    • Regulatory T cell lineage specification by the forkhead transcription factor foxp3
    • Fontenot JD, Rasmussen JP, Williams LM, et al. Regulatory T cell lineage specification by the forkhead transcription factor foxp3. Immunity 2005;22:329-41
    • (2005) Immunity , vol.22 , pp. 329-341
    • Fontenot, J.D.1    Rasmussen, J.P.2    Williams, L.M.3
  • 26
    • 34047174849 scopus 로고    scopus 로고
    • Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production
    • Allan SE, Crome SQ, Crellin NK, et al. Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production. Int Immunol 2007;19:345-54
    • (2007) Int Immunol , vol.19 , pp. 345-354
    • Allan, S.E.1    Crome, S.Q.2    Crellin, N.K.3
  • 28
    • 35448930435 scopus 로고    scopus 로고
    • - T cells by T cell receptor stimulation is TGF-β-dependent but does not confer a regulatory phenotype
    • - T cells by T cell receptor stimulation is TGF-β-dependent but does not confer a regulatory phenotype. Blood 2007;110:2983-90
    • (2007) Blood , vol.110 , pp. 2983-2990
    • Tran, D.Q.1    Ramsey, H.2    Shevach, E.M.3
  • 33
    • 33745813929 scopus 로고    scopus 로고
    • Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
    • Seddiki N, Santner-Nanan B, Martinson J, et al. Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J Exp Med 2006;203:1693-700
    • (2006) J Exp Med , vol.203 , pp. 1693-1700
    • Seddiki, N.1    Santner-Nanan, B.2    Martinson, J.3
  • 34
    • 0036721629 scopus 로고    scopus 로고
    • Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
    • Liyanage UK, Moore TT, Joo HG, et al. Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J Immunol 2002;169:2756-61
    • (2002) J Immunol , vol.169 , pp. 2756-2761
    • Liyanage, U.K.1    Moore, T.T.2    Joo, H.G.3
  • 35
    • 0141891466 scopus 로고    scopus 로고
    • Increased populations of regulatory T cells in peripheral blood and tumor-infiltrating lymphocytes in patients with gastric and esophageal cancers
    • Ichihara F, Kono K, Takahashi A, et al. Increased populations of regulatory T cells in peripheral blood and tumor-infiltrating lymphocytes in patients with gastric and esophageal cancers. Clin Cancer Res 2003;9:4404-8
    • (2003) Clin Cancer Res , vol.9 , pp. 4404-4408
    • Ichihara, F.1    Kono, K.2    Takahashi, A.3
  • 36
    • 33645286546 scopus 로고    scopus 로고
    • T cells, tumour immunity and immunotherapy
    • Zou W. Regulatory T cells, tumour immunity and immunotherapy. Nat Rev Immunol 2006;6:295-307
    • (2006) Nat Rev Immunol , vol.6 , pp. 295-307
    • Regulatory, Z.W.1
  • 38
    • 34250863911 scopus 로고    scopus 로고
    • FOXP3 Is an X-linked breast cancer suppressor gene and an important repressor of the HER-2/ErbB2 oncogene
    • Zuo T, Wang L, Morrison C, et al. FOXP3 Is an X-linked breast cancer suppressor gene and an important repressor of the HER-2/ErbB2 oncogene. Cell 2007;129:1275-86
    • (2007) Cell , vol.129 , pp. 1275-1286
    • Zuo, T.1    Wang, L.2    Morrison, C.3
  • 39
    • 42349092708 scopus 로고    scopus 로고
    • The regulatory T cell-associated transcription factor FoxP3 is expressed by tumor cells
    • Ebert LM, Tan BS, Browning J, et al. The regulatory T cell-associated transcription factor FoxP3 is expressed by tumor cells. Cancer Res 2008;68:3001-9
    • (2008) Cancer Res , vol.68 , pp. 3001-3009
    • Ebert, L.M.1    Tan, B.S.2    Browning, J.3
  • 40
    • 34548590227 scopus 로고    scopus 로고
    • Foxp3 expression in pancreatic carcinoma cells as a novel mechanism of immune evasion in cancer
    • Hinz S, Pagerols-Raluy L, Oberg HH, et al. Foxp3 expression in pancreatic carcinoma cells as a novel mechanism of immune evasion in cancer. Cancer Res 2007;67:8344-50
    • (2007) Cancer Res , vol.67 , pp. 8344-8350
    • Hinz, S.1    Pagerols-Raluy, L.2    Oberg, H.H.3
  • 46
    • 37249000377 scopus 로고    scopus 로고
    • Is FOXP3 expressed in cutaneous T-cell lymphomas?
    • Banham AH, Brown PJ, Lyne L, et al. Is FOXP3 expressed in cutaneous T-cell lymphomas? Eur J Haematol 2008;80:90-1
    • (2008) Eur J Haematol , vol.80 , pp. 90-91
    • Banham, A.H.1    Brown, P.J.2    Lyne, L.3
  • 47
    • 30944449468 scopus 로고    scopus 로고
    • + regulatory T cells at the single-cell level. Eur J Immunol 2006;36:245-6; author reply 6
    • + regulatory T cells at the single-cell level. Eur J Immunol 2006;36:245-6; author reply 6
  • 48
    • 44449131480 scopus 로고    scopus 로고
    • Isoform-specific inhibition of RORα-mediated transcriptional activation by human FOXP3
    • Du J, Huang C, Zhou B, et al. Isoform-specific inhibition of RORα-mediated transcriptional activation by human FOXP3. J Immunol 2008;180:4785-92
    • (2008) J Immunol , vol.180 , pp. 4785-4792
    • Du, J.1    Huang, C.2    Zhou, B.3
  • 49
    • 43549114840 scopus 로고    scopus 로고
    • Defense of the clone: Antibody 259D effectively labels human FOXP3 in a variety of applications
    • Fox BC, Bignone PA, Brown PJ, et al. Defense of the clone: antibody 259D effectively labels human FOXP3 in a variety of applications. Blood 2008;111:3897-9
    • (2008) Blood , vol.111 , pp. 3897-3899
    • Fox, B.C.1    Bignone, P.A.2    Brown, P.J.3
  • 50
    • 38049160744 scopus 로고    scopus 로고
    • Response: Anti human FOXP3 mAb PCH101 stains activated human naive T cells nonspecifically
    • Tran DQ, Shevach EM. Response: Anti human FOXP3 mAb PCH101 stains activated human naive T cells nonspecifically. Blood 2008;111:464-6
    • (2008) Blood , vol.111 , pp. 464-466
    • Tran, D.Q.1    Shevach, E.M.2
  • 51
    • 38049110724 scopus 로고    scopus 로고
    • Attack on the clones? Human FOXP3 detection by PCH101, 236A/E7, 206D, and 259D reveals 259D as the outlier with lower sensitivity
    • Pillai V, Karandikar NJ. Attack on the clones? Human FOXP3 detection by PCH101, 236A/E7, 206D, and 259D reveals 259D as the outlier with lower sensitivity. Blood 2008;111:463-4
    • (2008) Blood , vol.111 , pp. 463-464
    • Pillai, V.1    Karandikar, N.J.2
  • 52
    • 26844476814 scopus 로고    scopus 로고
    • The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis
    • Chang X, Gao JX, Jiang Q, et al. The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis. J Exp Med 2005;202:1141-51
    • (2005) J Exp Med , vol.202 , pp. 1141-1151
    • Chang, X.1    Gao, J.X.2    Jiang, Q.3
  • 53
    • 36849053106 scopus 로고    scopus 로고
    • FOXP3 is a novel transcriptional repressor for the breast cancer oncogene SKP2
    • Zuo T, Liu RCD, Zhang H, et al. FOXP3 is a novel transcriptional repressor for the breast cancer oncogene SKP2. J Clin Invest 2007;117:3765-73
    • (2007) J Clin Invest , vol.117 , pp. 3765-3773
    • Zuo, T.1    Liu, R.C.D.2    Zhang, H.3
  • 54
    • 45949099261 scopus 로고    scopus 로고
    • Cutting Edge: Broad expression of the FoxP3 locus in epithelial cells: a caution against early interpretation of fatal inflammatory diseases following in vivo depletion of FoxP3- expressing cells
    • Chen G, Chen C, Wang L, et al. Cutting Edge: Broad expression of the FoxP3 locus in epithelial cells: a caution against early interpretation of fatal inflammatory diseases following in vivo depletion of FoxP3- expressing cells. J Immunol 2008;180:5163-6
    • (2008) J Immunol , vol.180 , pp. 5163-5166
    • Chen, G.1    Chen, C.2    Wang, L.3
  • 55
    • 33947427514 scopus 로고    scopus 로고
    • Lack of Foxp3 function and expression in the thymic epithelium
    • Liston A, Farr AG, Chen Z, et al. Lack of Foxp3 function and expression in the thymic epithelium. J Exp Med 2007;204:475-80
    • (2007) J Exp Med , vol.204 , pp. 475-480
    • Liston, A.1    Farr, A.G.2    Chen, Z.3
  • 56
    • 34247261531 scopus 로고    scopus 로고
    • Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse
    • Bates GJ, Fox SB, Han C, et al. Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse. J Clin Oncol 2006;24:5373-80
    • (2006) J Clin Oncol , vol.24 , pp. 5373-5380
    • Bates, G.J.1    Fox, S.B.2    Han, C.3
  • 57
    • 3042838753 scopus 로고    scopus 로고
    • + regulatory T cells, in adult T-cell leukaemia/ lymphoma cells
    • + regulatory T cells, in adult T-cell leukaemia/ lymphoma cells. Br J Haematol 2004;126:81-4
    • (2004) Br J Haematol , vol.126 , pp. 81-84
    • Karube, K.1    Ohshima, K.2    Tsuchiya, T.3
  • 58
    • 28544443601 scopus 로고    scopus 로고
    • FOXP3, a selective marker for a subset of adult T-cell leukaemia/lymphoma
    • Roncador G, Garcia JF, Maestre L, et al. FOXP3, a selective marker for a subset of adult T-cell leukaemia/lymphoma. Leukemia 2005;19:2247-53
    • (2005) Leukemia , vol.19 , pp. 2247-2253
    • Roncador, G.1    Garcia, J.F.2    Maestre, L.3
  • 59
    • 33646593910 scopus 로고    scopus 로고
    • Paucity of FOXP3+ cells in skin and peripheral blood distinguishes Sézary syndrome from other cutaneous T-cell lymphomas
    • Klemke CD, Fritzsching B, Franz B, et al. Paucity of FOXP3+ cells in skin and peripheral blood distinguishes Sézary syndrome from other cutaneous T-cell lymphomas. Leukemia 2006;20:1123-9
    • (2006) Leukemia , vol.20 , pp. 1123-1129
    • Klemke, C.D.1    Fritzsching, B.2    Franz, B.3
  • 60
    • 33846982577 scopus 로고    scopus 로고
    • Regulatory T-cell phenotype in association with large cell transformation of mycosis fungoides
    • Hallermann C, Niermann C, Schulze HJ. Regulatory T-cell phenotype in association with large cell transformation of mycosis fungoides. Eur J Haematol 2007;78:260-3
    • (2007) Eur J Haematol , vol.78 , pp. 260-263
    • Hallermann, C.1    Niermann, C.2    Schulze, H.J.3
  • 61
    • 33745587303 scopus 로고    scopus 로고
    • Nucleophosmin/anaplastic lymphoma kinase (NPM/ALK) oncoprotein induces the T regulatory cell phenotype by activating STAT3
    • Kasprzycka M, Marzec M, Liu X, et al. Nucleophosmin/anaplastic lymphoma kinase (NPM/ALK) oncoprotein induces the T regulatory cell phenotype by activating STAT3. Proc Natl Acad Sci USA 2006;103:9964-9
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 9964-9969
    • Kasprzycka, M.1    Marzec, M.2    Liu, X.3
  • 62
    • 33644859773 scopus 로고    scopus 로고
    • Assigning the phenotype of a natural regulatory T-cell to the human T-cell line, KARPAS-299
    • Wolke C, Tadje J, Bukowska A, et al. Assigning the phenotype of a natural regulatory T-cell to the human T-cell line, KARPAS-299. Int J Mol Med 2006;17:275-8
    • (2006) Int J Mol Med , vol.17 , pp. 275-278
    • Wolke, C.1    Tadje, J.2    Bukowska, A.3
  • 63
    • 43549097133 scopus 로고    scopus 로고
    • FOXP3 positive regulatory T-cells in cutaneous and systemic CD30 positive T-cell lymphoproliferations
    • Gjerdrum LM, Woetmann A, Odum N, et al. FOXP3 positive regulatory T-cells in cutaneous and systemic CD30 positive T-cell lymphoproliferations. Eur J Haematol 2008;80:483-9
    • (2008) Eur J Haematol , vol.80 , pp. 483-489
    • Gjerdrum, L.M.1    Woetmann, A.2    Odum, N.3
  • 64
    • 36348953150 scopus 로고    scopus 로고
    • + regulatory T cells in cutaneous T-cell lymphomas: Association with disease stage and survival
    • + regulatory T cells in cutaneous T-cell lymphomas: association with disease stage and survival. Leukemia 2007;21:2512-8
    • (2007) Leukemia , vol.21 , pp. 2512-2518
    • Gjerdrum, L.M.1    Woetmann, A.2    Odum, N.3
  • 65
    • 42549122539 scopus 로고    scopus 로고
    • The relationship of FOXP3 expression and clinicopathological characteristics in adult T-cell leukemia/ lymphoma
    • Karube K, Aoki R, Sugita Y, et al. The relationship of FOXP3 expression and clinicopathological characteristics in adult T-cell leukemia/ lymphoma. Mod Pathol 2008;21:617-25
    • (2008) Mod Pathol , vol.21 , pp. 617-625
    • Karube, K.1    Aoki, R.2    Sugita, Y.3
  • 66
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • Curiel TJ, Coukos G, Zou L, et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med 2004;10:942-9
    • (2004) Nat Med , vol.10 , pp. 942-949
    • Curiel, T.J.1    Coukos, G.2    Zou, L.3
  • 67
    • 35348825514 scopus 로고    scopus 로고
    • Wolf AM, Rumpold H, Wolf D, et al. Role of forkhead box protein 3 expression in invasive breast cancer. J Clin Oncol 2007;25:4499-500; author reply 500-1
    • Wolf AM, Rumpold H, Wolf D, et al. Role of forkhead box protein 3 expression in invasive breast cancer. J Clin Oncol 2007;25:4499-500; author reply 500-1
  • 68
    • 34547210257 scopus 로고    scopus 로고
    • Intratumoral FOXP3 expression in infiltrating breast carcinoma: Its association with clinicopathologic parameters and angiogenesis
    • Gupta S, Joshi K, Wig JD, et al. Intratumoral FOXP3 expression in infiltrating breast carcinoma: Its association with clinicopathologic parameters and angiogenesis. Acta oncologica 2007;46:792-7
    • (2007) Acta oncologica , vol.46 , pp. 792-797
    • Gupta, S.1    Joshi, K.2    Wig, J.D.3
  • 69
    • 42049111164 scopus 로고    scopus 로고
    • Ghebeh H, Barhoush E, Tulbah A, et al. FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy. BMC Cancer 2008;8:57. published online 23 February 2008, doi:10.1186/1471-2407-8-57
    • Ghebeh H, Barhoush E, Tulbah A, et al. FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy. BMC Cancer 2008;8:57. published online 23 February 2008, doi:10.1186/1471-2407-8-57
  • 71
    • 20044367117 scopus 로고    scopus 로고
    • Outcome in Hodgkin's lymphoma can be predicted from the presence of accompanying cytotoxic and regulatory T cells
    • Alvaro T, Lejeune M, Salvadó MT, et al. Outcome in Hodgkin's lymphoma can be predicted from the presence of accompanying cytotoxic and regulatory T cells. Clin Cancer Res 2005;11:1467-73
    • (2005) Clin Cancer Res , vol.11 , pp. 1467-1473
    • Alvaro, T.1    Lejeune, M.2    Salvadó, M.T.3
  • 72
    • 33751194652 scopus 로고    scopus 로고
    • High numbers of tumor-infiltrating FOXP3-positive regulatory T cells are associated with improved overall survival in follicular lymphoma
    • Carreras J, Lopez-Guillermo A, Fox BC, et al. High numbers of tumor-infiltrating FOXP3-positive regulatory T cells are associated with improved overall survival in follicular lymphoma. Blood 2006;108:2957-64
    • (2006) Blood , vol.108 , pp. 2957-2964
    • Carreras, J.1    Lopez-Guillermo, A.2    Fox, B.C.3
  • 73
    • 33750964740 scopus 로고    scopus 로고
    • + cells and location of forkhead box protein P3-positive cells in diagnostic follicular lymphoma tissue microarrays correlates with outcome
    • + cells and location of forkhead box protein P3-positive cells in diagnostic follicular lymphoma tissue microarrays correlates with outcome. J Clin Oncol 2006;24:5052-9
    • (2006) J Clin Oncol , vol.24 , pp. 5052-5059
    • Lee, A.M.1    Clear, A.J.2    Calaminici, M.3
  • 75
    • 40849126992 scopus 로고    scopus 로고
    • + regulatory T cells with improved survival in germinal center-like diffuse large B-cell lymphoma, follicular lymphoma and classical Hodgkin's lymphoma
    • + regulatory T cells with improved survival in germinal center-like diffuse large B-cell lymphoma, follicular lymphoma and classical Hodgkin's lymphoma. Haematologica 2008;93:193-200
    • (2008) Haematologica , vol.93 , pp. 193-200
    • Tzankov, A.1    Meier, C.2    Hirschmann, P.3
  • 78
    • 37149013899 scopus 로고    scopus 로고
    • Biologic predictors in follicular lymphoma: Importance of markers of immune response
    • Kelley T, Beck R, Absi A, et al. Biologic predictors in follicular lymphoma: importance of markers of immune response. Leuk Lymphoma 2007;48:2403-11
    • (2007) Leuk Lymphoma , vol.48 , pp. 2403-2411
    • Kelley, T.1    Beck, R.2    Absi, A.3
  • 79
    • 45249085670 scopus 로고    scopus 로고
    • Rituximab-induced B cell depletion in autoimmune diseases: Potential effects on T cells
    • Liossis SN, Sfikakis PP. Rituximab-induced B cell depletion in autoimmune diseases: potential effects on T cells. Clin Immunol 2008;127:280-5
    • (2008) Clin Immunol , vol.127 , pp. 280-285
    • Liossis, S.N.1    Sfikakis, P.P.2
  • 80
    • 35948980739 scopus 로고    scopus 로고
    • Deacetylase inhibition promotes the generation and function of regulatory T cells
    • Tao R, de Zoeten EF, Ozkaynak E, et al. Deacetylase inhibition promotes the generation and function of regulatory T cells. Nat Med 2007;13:1299-307
    • (2007) Nat Med , vol.13 , pp. 1299-1307
    • Tao, R.1    de Zoeten, E.F.2    Ozkaynak, E.3
  • 81
    • 50549098084 scopus 로고    scopus 로고
    • Wang R, Wan Q, Kozhaya L, et al. Identification of a regulatory T cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 expression. PLoS One 2008;3:e2705. published online 16 July 2008, doi:10.1371/journal.pone.0002705
    • Wang R, Wan Q, Kozhaya L, et al. Identification of a regulatory T cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 expression. PLoS One 2008;3:e2705. published online 16 July 2008, doi:10.1371/journal.pone.0002705
  • 82
    • 0027984836 scopus 로고
    • The GARP gene encodes a new member of the family of leucine-rich repeat-containing proteins
    • Ollendorff V, Noguchi T, deLapeyriere O, et al. The GARP gene encodes a new member of the family of leucine-rich repeat-containing proteins. Cell Growth Differ 1994;5:213-9
    • (1994) Cell Growth Differ , vol.5 , pp. 213-219
    • Ollendorff, V.1    Noguchi, T.2    deLapeyriere, O.3
  • 83
    • 11144358198 scopus 로고    scopus 로고
    • A gene atlas of the mouse and human protein-encoding transcriptomes
    • Su AI, Wiltshire T, Batalov S, et al. A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci USA 2004;101:6062-7. http://symatlas.gnf.org/SymAtlas/
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 6062-6067
    • Su, A.I.1    Wiltshire, T.2    Batalov, S.3
  • 84
    • 0032568655 scopus 로고    scopus 로고
    • SMART, a simple modular architecture research tool: Identification of signaling domains
    • Schultz J, Milpetz F, Bork P, et al. SMART, a simple modular architecture research tool: identification of signaling domains. Proc Natl Acad Sci USA 1998;95:5857-64. http://smart.embl-heidelberg.de/
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 5857-5864
    • Schultz, J.1    Milpetz, F.2    Bork, P.3
  • 85
    • 33846039019 scopus 로고    scopus 로고
    • Ensembl 2007. Nucleic Acids Res 2007;35:D610-7
    • Ensembl release 50, Jul
    • Hubbard TJ, Aken BL, Beal K, et al. Ensembl 2007. Nucleic Acids Res 2007;35:D610-7. http://www.ensembl.org/[Ensembl release 50 - Jul 2008]
    • (2008)
    • Hubbard, T.J.1    Aken, B.L.2    Beal, K.3
  • 86
    • 0142250482 scopus 로고    scopus 로고
    • Bach JF. Regulatory T cells under scrutiny. Nat Rev Immunol 2003;3:189-98
    • Bach JF. Regulatory T cells under scrutiny. Nat Rev Immunol 2003;3:189-98
  • 87
    • 8644249136 scopus 로고    scopus 로고
    • + regulatory T cells in the maintenance of T cell homeostasis
    • + regulatory T cells in the maintenance of T cell homeostasis. J Exp Med 2004;200:1123-34
    • (2004) J Exp Med , vol.200 , pp. 1123-1134
    • Rifa'i, M.1    Kawamoto, Y.2    Nakashima, I.3
  • 88
    • 27644585757 scopus 로고    scopus 로고
    • Akdis M, Blaser K, Akdis CA. T regulatory cells in allergy: novel concepts in the pathogenesis, prevention, and treatment of allergic diseases. J Allergy Clin Immunol 2005;116:961-8; quiz 9
    • Akdis M, Blaser K, Akdis CA. T regulatory cells in allergy: novel concepts in the pathogenesis, prevention, and treatment of allergic diseases. J Allergy Clin Immunol 2005;116:961-8; quiz 9
  • 89
    • 0037093217 scopus 로고    scopus 로고
    • + immune regulatory cells inhibits graft-versus-host disease lethality
    • + immune regulatory cells inhibits graft-versus-host disease lethality. Blood 2002;99:3493-9
    • (2002) Blood , vol.99 , pp. 3493-3499
    • Taylor, P.A.1    Lees, C.J.2    Blazar, B.R.3
  • 90
    • 21244433093 scopus 로고    scopus 로고
    • + T lymphocytes from MHC class II-deficient mice exhibit regulatory activity
    • + T lymphocytes from MHC class II-deficient mice exhibit regulatory activity. J Immunol 2005;175:246-53
    • (2005) J Immunol , vol.175 , pp. 246-253
    • Bienvenu, B.1    Martin, B.2    Auffray, C.3
  • 92
    • 20444485236 scopus 로고    scopus 로고
    • + regulatory T cells in human ovarian carcinoma
    • + regulatory T cells in human ovarian carcinoma. Cancer Res 2005;65:5020-6
    • (2005) Cancer Res , vol.65 , pp. 5020-5026
    • Wei, S.1    Kryczek, I.2    Zou, L.3
  • 93
    • 33749317518 scopus 로고    scopus 로고
    • + regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions
    • + regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions. Clin Cancer Res 2006;12:5423-34
    • (2006) Clin Cancer Res , vol.12 , pp. 5423-5434
    • Hiraoka, N.1    Onozato, K.2    Kosuge, T.3
  • 96
    • 16244409219 scopus 로고    scopus 로고
    • + regulatory T cells in the peripheral circulation of patients with head and neck cancer
    • + regulatory T cells in the peripheral circulation of patients with head and neck cancer. Br J Cancer 2005; 92:913-20
    • (2005) Br J Cancer , vol.92 , pp. 913-920
    • Schaefer, C.1    Kim, G.G.2    Albers, A.E.3
  • 97
    • 25844435263 scopus 로고    scopus 로고
    • Immune responses to p53 in patients with cancer: Enrichment in tetramer+ p53 peptide-specific T cells and regulatory T cells at tumor sites
    • Albers AE, Ferris RL, Kim GG, et al. Immune responses to p53 in patients with cancer: enrichment in tetramer+ p53 peptide-specific T cells and regulatory T cells at tumor sites. Cancer Immunol Immunother 2005;54:1072-81
    • (2005) Cancer Immunol Immunother , vol.54 , pp. 1072-1081
    • Albers, A.E.1    Ferris, R.L.2    Kim, G.G.3
  • 98
    • 46849090082 scopus 로고    scopus 로고
    • Bose A, Chakraborty T, Chakraborty K, et al. Dysregulation in immune functions is reflected in tumor cell cytotoxicity by peripheral blood mononuclear cells from head and neck squamous cell carcinoma patients. Cancer Immun 2008;8:10. Published online 12 June 2008 http://www.cancerimmunity.org/v8p10/080511.htm [Last accessed 27 September 2008]
    • Bose A, Chakraborty T, Chakraborty K, et al. Dysregulation in immune functions is reflected in tumor cell cytotoxicity by peripheral blood mononuclear cells from head and neck squamous cell carcinoma patients. Cancer Immun 2008;8:10. Published online 12 June 2008 http://www.cancerimmunity.org/v8p10/080511.htm [Last accessed 27 September 2008]
  • 99
    • 34250005419 scopus 로고    scopus 로고
    • Increased regulatory T cells correlate with CD8 T-cell impairment and poor survival in hepatocellular carcinoma patients
    • Fu J, Xu D, Liu Z, et al. Increased regulatory T cells correlate with CD8 T-cell impairment and poor survival in hepatocellular carcinoma patients. Gastroenterology 2007;132:2328-39
    • (2007) Gastroenterology , vol.132 , pp. 2328-2339
    • Fu, J.1    Xu, D.2    Liu, Z.3
  • 100
    • 33847384529 scopus 로고    scopus 로고
    • + regulatory T cells affect the development and progression of hepatocarcinogenesis
    • + regulatory T cells affect the development and progression of hepatocarcinogenesis. Clin Cancer Res 2007;13:902-11
    • (2007) Clin Cancer Res , vol.13 , pp. 902-911
    • Kobayashi, N.1    Hiraoka, N.2    Yamagami, W.3
  • 101
    • 34447277894 scopus 로고    scopus 로고
    • Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection
    • Gao Q, Qiu SJ, Fan J, et al. Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection. J Clin Oncol 2007;25:2586-93
    • (2007) J Clin Oncol , vol.25 , pp. 2586-2593
    • Gao, Q.1    Qiu, S.J.2    Fan, J.3
  • 102
    • 38149047571 scopus 로고    scopus 로고
    • + regulatory T cells in patients with hepatocellular carcinoma
    • + regulatory T cells in patients with hepatocellular carcinoma. Eur J Surg Oncol 2008;34:173-9
    • (2008) Eur J Surg Oncol , vol.34 , pp. 173-179
    • Sasaki, A.1    Tanaka, F.2    Mimori, K.3
  • 103
    • 33750630223 scopus 로고    scopus 로고
    • + T cells in peripheral blood from advanced pancreatic cancer patients
    • + T cells in peripheral blood from advanced pancreatic cancer patients. Pancreas 2006;33:386-90
    • (2006) Pancreas , vol.33 , pp. 386-390
    • Ikemoto, T.1    Yamaguchi, T.2    Morine, Y.3
  • 104
    • 57649223213 scopus 로고    scopus 로고
    • + regulatory T cells in human colorectal cancer. J Transl Med 2006;4:52. published online 13 December 2006, doi:10.1186/ 1479-5876-4-52
    • + regulatory T cells in human colorectal cancer. J Transl Med 2006;4:52. published online 13 December 2006, doi:10.1186/ 1479-5876-4-52
  • 105
    • 34047141055 scopus 로고    scopus 로고
    • Increased frequency of regulatory T cells in peripheral blood and tumour infiltrating lymphocytes in colorectal cancer patients
    • published online 28 March 2007. Available from:, Last accessed 27 September 2008
    • Ling KL, Pratap SE, Bates GJ, et al. Increased frequency of regulatory T cells in peripheral blood and tumour infiltrating lymphocytes in colorectal cancer patients. Cancer Immun 2007;7:7, published online 28 March 2007. Available from: http://www.cancerimmunity.org/v7p7/ 070206.htm [Last accessed 27 September 2008]
    • (2007) Cancer Immun , vol.7 , pp. 7
    • Ling, K.L.1    Pratap, S.E.2    Bates, G.J.3
  • 106
    • 54949139152 scopus 로고    scopus 로고
    • + regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer. PLoS One 2006;1:e129 published online 27 December 2006, doi:10.1371/ journal. pone.0000129
    • + regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer. PLoS One 2006;1:e129 published online 27 December 2006, doi:10.1371/ journal. pone.0000129
  • 107
    • 33745215983 scopus 로고    scopus 로고
    • Tumor-infiltrating cytotoxic T cells but not regulatory T cells predict outcome in anal squamous cell carcinoma
    • Grabenbauer GG, Lahmer G, Distel L, et al. Tumor-infiltrating cytotoxic T cells but not regulatory T cells predict outcome in anal squamous cell carcinoma. Clin Cancer Res 2006;12:3355-60
    • (2006) Clin Cancer Res , vol.12 , pp. 3355-3360
    • Grabenbauer, G.G.1    Lahmer, G.2    Distel, L.3
  • 108
    • 35748930538 scopus 로고    scopus 로고
    • Leukocyte infiltration and tumor cell plasticity are parameters of aggressiveness in primary cutaneous melanoma
    • Hillen F, Baeten CI, van de Winkel A, et al. Leukocyte infiltration and tumor cell plasticity are parameters of aggressiveness in primary cutaneous melanoma. Cancer Immunol Immunother 2008;57:97-106
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 97-106
    • Hillen, F.1    Baeten, C.I.2    van de Winkel, A.3
  • 109
    • 39149136504 scopus 로고    scopus 로고
    • Phase- and stage-related proportions of T cells bearing the transcription factor FOXP3 infiltrate primary melanoma
    • De Panfilis G, Campanini N, Santini M, et al. Phase- and stage-related proportions of T cells bearing the transcription factor FOXP3 infiltrate primary melanoma. J Invest Dermatol 2008;128:676-84
    • (2008) J Invest Dermatol , vol.128 , pp. 676-684
    • De Panfilis, G.1    Campanini, N.2    Santini, M.3
  • 110
    • 52549083059 scopus 로고    scopus 로고
    • + T cells in metastatic tumor lesions from melanoma patients compared to peripheral blood
    • + T cells in metastatic tumor lesions from melanoma patients compared to peripheral blood. Cancer Immunol Immunother 2008;57(12):1795-805
    • (2008) Cancer Immunol Immunother , vol.57 , Issue.12 , pp. 1795-1805
    • Jandus, C.1    Bioley, G.2    Speiser, D.3
  • 111
    • 33748532939 scopus 로고    scopus 로고
    • The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses
    • Hussain SF, Yang D, Suki D, et al. The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses. Neurooncol 2006;8:261-79
    • (2006) Neurooncol , vol.8 , pp. 261-279
    • Hussain, S.F.1    Yang, D.2    Suki, D.3
  • 112
    • 34249054990 scopus 로고    scopus 로고
    • + T-cell infiltration and heme oxygenase-1 expression correlate with tumor grade in human gliomas
    • + T-cell infiltration and heme oxygenase-1 expression correlate with tumor grade in human gliomas. J Neurooncol 2007;83:145-52
    • (2007) J Neurooncol , vol.83 , pp. 145-152
    • El Andaloussi, A.1    Lesniak, M.S.2
  • 113
    • 33750807427 scopus 로고    scopus 로고
    • high T cells are enriched in the tumor and peripheral blood of prostate cancer patients
    • high T cells are enriched in the tumor and peripheral blood of prostate cancer patients. J Immunol 2006;177:7398-405
    • (2006) J Immunol , vol.177 , pp. 7398-7405
    • Miller, A.M.1    Lundberg, K.2    Ozenci, V.3
  • 114
    • 34247618152 scopus 로고    scopus 로고
    • The number of regulatory T cells in prostate cancer is associated with the androgen receptor and hypoxia-inducible factor (HIF)-2α but not HIF-1α
    • Fox SB, Bates GJ, Han C, et al. The number of regulatory T cells in prostate cancer is associated with the androgen receptor and hypoxia-inducible factor (HIF)-2α but not HIF-1α. Prostate 2007;67:623-9
    • (2007) Prostate , vol.67 , pp. 623-629
    • Fox, S.B.1    Bates, G.J.2    Han, C.3
  • 115
    • 39749142196 scopus 로고    scopus 로고
    • + regulatory T cells in the peripheral blood of patients with prostate cancer
    • + regulatory T cells in the peripheral blood of patients with prostate cancer. Clin Cancer Res 2008;14:1032-40
    • (2008) Clin Cancer Res , vol.14 , pp. 1032-1040
    • Yokokawa, J.1    Cereda, V.2    Remondo, C.3
  • 116
    • 33845311502 scopus 로고    scopus 로고
    • Human bladder carcinoma is dominated by T-regulatory cells and Th1 inhibitory cytokines
    • Loskog AS, Ninalga C, Paul-Wetterberg G, et al. Human bladder carcinoma is dominated by T-regulatory cells and Th1 inhibitory cytokines. J Urol 2007;177:353-8
    • (2007) J Urol , vol.177 , pp. 353-358
    • Loskog, A.S.1    Ninalga, C.2    Paul-Wetterberg, G.3
  • 117
    • 29444442811 scopus 로고    scopus 로고
    • +/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer
    • +/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer. Proc Natl Acad Sci USA 2005;102:18538-43
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 18538-18543
    • Sato, E.1    Olson, S.H.2    Ahn, J.3
  • 118
    • 42749092358 scopus 로고    scopus 로고
    • Intratumoral T cells, tumor-associated macrophages, and regulatory T cells: Association with p53 mutations, circulating tumor DNA and survival in women with ovarian cancer
    • Shah CA, Allison KH, Garcia RL, et al. Intratumoral T cells, tumor-associated macrophages, and regulatory T cells: Association with p53 mutations, circulating tumor DNA and survival in women with ovarian cancer. Gynecol Oncol 2008;109:215-9
    • (2008) Gynecol Oncol , vol.109 , pp. 215-219
    • Shah, C.A.1    Allison, K.H.2    Garcia, R.L.3
  • 119
    • 47249112494 scopus 로고    scopus 로고
    • + lymphocytes correlates with intratumoral angiogenesis in endometrial cancer
    • + lymphocytes correlates with intratumoral angiogenesis in endometrial cancer. Gynecol Oncol 2008; 110:216-21
    • (2008) Gynecol Oncol , vol.110 , pp. 216-221
    • Giatromanolaki, A.1    Bates, G.2    Koukourakis, M.3
  • 120
    • 42249094710 scopus 로고    scopus 로고
    • +/regulatory T-cell ratio: Which variable determines survival of cervical cancer patients?
    • +/regulatory T-cell ratio: Which variable determines survival of cervical cancer patients? Clin Cancer Res 2008;14:2028-35
    • (2008) Clin Cancer Res , vol.14 , pp. 2028-2035
    • Jordanova, E.S.1    Gorter, A.2    Ayachi, O.3
  • 121
    • 34548162594 scopus 로고    scopus 로고
    • Frequency of regulatory T cells in renal cell carcinoma patients and investigation of correlation with survival
    • Griffiths RW, Elkord E, Gilham DE, et al. Frequency of regulatory T cells in renal cell carcinoma patients and investigation of correlation with survival. Cancer Immunol Immunother 2007;56:1743-53
    • (2007) Cancer Immunol Immunother , vol.56 , pp. 1743-1753
    • Griffiths, R.W.1    Elkord, E.2    Gilham, D.E.3
  • 122
    • 33847183114 scopus 로고    scopus 로고
    • high regulatory T cells in nasopharyngeal carcinoma patients
    • high regulatory T cells in nasopharyngeal carcinoma patients. Br J Cancer 2007;96:617-22
    • (2007) Br J Cancer , vol.96 , pp. 617-622
    • Lau, K.M.1    Cheng, S.H.2    Lo, K.W.3
  • 123
    • 33646371011 scopus 로고    scopus 로고
    • - T regulatory cells in the peripheral blood of patients with lung cancer and pleural mesothelioma
    • - T regulatory cells in the peripheral blood of patients with lung cancer and pleural mesothelioma. Hum Immunol 2006;67:1-12
    • (2006) Hum Immunol , vol.67 , pp. 1-12
    • Meloni, F.1    Morosini, M.2    Solari, N.3
  • 124
    • 33845590308 scopus 로고    scopus 로고
    • + regulatory T-cells are associated with recurrence in pathologic stage I NSCLC patients
    • + regulatory T-cells are associated with recurrence in pathologic stage I NSCLC patients. Cancer 2006;107:2866-72
    • (2006) Cancer , vol.107 , pp. 2866-2872
    • Petersen, R.P.1    Campa, M.J.2    Sperlazza, J.3
  • 125
    • 40949119354 scopus 로고    scopus 로고
    • Impact of tumor-infiltrating T cells on survival in patients with malignant pleural mesothelioma
    • Anraku M, Cunningham KS, Yun Z, et al. Impact of tumor-infiltrating T cells on survival in patients with malignant pleural mesothelioma. J Thorac Cardiovasc Surg 2008;135:823-9
    • (2008) J Thorac Cardiovasc Surg , vol.135 , pp. 823-829
    • Anraku, M.1    Cunningham, K.S.2    Yun, Z.3
  • 127
    • 38049064586 scopus 로고    scopus 로고
    • + regulatory T cells is associated with clinical behaviour in gastric cancer
    • + regulatory T cells is associated with clinical behaviour in gastric cancer. Br J Cancer 2008;98:148-53
    • (2008) Br J Cancer , vol.98 , pp. 148-153
    • Mizukami, Y.1    Kono, K.2    Kawaguchi, Y.3
  • 128
    • 49749084339 scopus 로고    scopus 로고
    • Intratumoural FOXP3-positive regulatory T cells are associated with adverse prognosis in radically resected gastric cancer
    • Perrone G, Ruffini PA, Catalano V, et al. Intratumoural FOXP3-positive regulatory T cells are associated with adverse prognosis in radically resected gastric cancer. Eur J Cancer 2008;44(13):1875-82
    • (2008) Eur J Cancer , vol.44 , Issue.13 , pp. 1875-1882
    • Perrone, G.1    Ruffini, P.A.2    Catalano, V.3
  • 129
    • 41649100482 scopus 로고    scopus 로고
    • Infiltrating regulatory T cell numbers is not a factor to predict patient's survival in oesophageal squamous cell carcinoma
    • Yoshioka T, Miyamoto M, Cho Y, et al. Infiltrating regulatory T cell numbers is not a factor to predict patient's survival in oesophageal squamous cell carcinoma. Br J Cancer 2008;98:1258-63
    • (2008) Br J Cancer , vol.98 , pp. 1258-1263
    • Yoshioka, T.1    Miyamoto, M.2    Cho, Y.3
  • 130
    • 49249098896 scopus 로고    scopus 로고
    • + regulatory T cells in oral squamous cell carcinomas detected by chromogenic immunohistochemical double staining
    • + regulatory T cells in oral squamous cell carcinomas detected by chromogenic immunohistochemical double staining. J Oral Pathol Med 2008;37(8):485-9
    • (2008) J Oral Pathol Med , vol.37 , Issue.8 , pp. 485-489
    • Schwarz, S.1    Butz, M.2    Morsczeck, C.3
  • 131
    • 33646575622 scopus 로고    scopus 로고
    • + regulatory T cells in patients with multiple myeloma
    • + regulatory T cells in patients with multiple myeloma. Blood 2006;107:3940-9
    • (2006) Blood , vol.107 , pp. 3940-3949
    • Beyer, M.1    Kochanek, M.2    Giese, T.3
  • 132
    • 25844507839 scopus 로고    scopus 로고
    • Possible origin of adult T-cell leukemia/lymphoma cells from human T lymphotropic virus type-1-infected regulatory T cells
    • Kohno T, Yamada Y, Akamatsu N, et al. Possible origin of adult T-cell leukemia/lymphoma cells from human T lymphotropic virus type-1-infected regulatory T cells. Cancer Sci 2005;96:527-33
    • (2005) Cancer Sci , vol.96 , pp. 527-533
    • Kohno, T.1    Yamada, Y.2    Akamatsu, N.3
  • 133
    • 33947283839 scopus 로고    scopus 로고
    • Regulatory T-cell function of adult T-cell leukemia/lymphoma cells
    • Yano H, Ishida T, Inagaki A, et al. Regulatory T-cell function of adult T-cell leukemia/lymphoma cells. Int J Cancer 2007;120:2052-7
    • (2007) Int J Cancer , vol.120 , pp. 2052-2057
    • Yano, H.1    Ishida, T.2    Inagaki, A.3
  • 135
    • 46749101778 scopus 로고    scopus 로고
    • Expression of T-plastin, FoxP3 and other tumor-associated markers by leukemic T-cells of cutaneous T-cell lymphoma
    • Capriotti E, Vonderheid EC, Thoburn CJ, et al. Expression of T-plastin, FoxP3 and other tumor-associated markers by leukemic T-cells of cutaneous T-cell lymphoma. Leuk Lymphoma 2008;49:1190-201
    • (2008) Leuk Lymphoma , vol.49 , pp. 1190-1201
    • Capriotti, E.1    Vonderheid, E.C.2    Thoburn, C.J.3
  • 136
    • 38049022492 scopus 로고    scopus 로고
    • + cytotoxic T/NK cells predicts prognosis in classical Hodgkin lymphoma and is independent of bcl-2 and MAL expression
    • + cytotoxic T/NK cells predicts prognosis in classical Hodgkin lymphoma and is independent of bcl-2 and MAL expression. Am J Clin Pathol 2007;128:958-65
    • (2007) Am J Clin Pathol , vol.128 , pp. 958-965
    • Kelley, T.W.1    Pohlman, B.2    Elson, P.3
  • 137
    • 38849133434 scopus 로고    scopus 로고
    • Prognostic impact of tumor infiltrating FOXP3 positive regulatory T cells in diffuse large B-cell lymphoma at diagnosis
    • Lee NR, Song EK, Jang KY, et al. Prognostic impact of tumor infiltrating FOXP3 positive regulatory T cells in diffuse large B-cell lymphoma at diagnosis. Leak Lymphoma 2008;49:247-56
    • (2008) Leak Lymphoma , vol.49 , pp. 247-256
    • Lee, N.R.1    Song, E.K.2    Jang, K.Y.3
  • 138
    • 34247190110 scopus 로고    scopus 로고
    • Immunohistochemical patterns of reactive microenvironment are associated with clinicobiologic behavior in follicular lymphoma patients
    • Alvaro T, Lejeune M, Salvadó MT, et al. Immunohistochemical patterns of reactive microenvironment are associated with clinicobiologic behavior in follicular lymphoma patients. J Clin Oncol 2006;24:5350-7
    • (2006) J Clin Oncol , vol.24 , pp. 5350-5357
    • Alvaro, T.1    Lejeune, M.2    Salvadó, M.T.3
  • 139
    • 33846974737 scopus 로고    scopus 로고
    • Gene-expression and immunohistochemical study of specific T-cell subsets and accessory cell types in the transformation and prognosis of follicular lymphoma
    • Glas AM, Knoops L, Delahaye L, et al. Gene-expression and immunohistochemical study of specific T-cell subsets and accessory cell types in the transformation and prognosis of follicular lymphoma. J Clin Oncol 2007;25:390-8
    • (2007) J Clin Oncol , vol.25 , pp. 390-398
    • Glas, A.M.1    Knoops, L.2    Delahaye, L.3
  • 140
    • 34547957665 scopus 로고    scopus 로고
    • + regulatory T cells in myelodysplastic syndrome (MDS)
    • + regulatory T cells in myelodysplastic syndrome (MDS). Blood 2007;110:847-50
    • (2007) Blood , vol.110 , pp. 847-850
    • Kordasti, S.Y.1    Ingram, W.2    Hayden, J.3
  • 142
    • 33750535641 scopus 로고    scopus 로고
    • + regulatory T cells in B-cell non-Hodgkin's lymphoma
    • + regulatory T cells in B-cell non-Hodgkin's lymphoma. Cancer Res 2006;66:10145-52
    • (2006) Cancer Res , vol.66 , pp. 10145-10152
    • Yang, Z.Z.1    Novak, A.J.2    Ziesmer, S.C.3
  • 143
    • 44749086828 scopus 로고    scopus 로고
    • + regulatory T cell population by non-Hodgkin's lymphoma
    • + regulatory T cell population by non-Hodgkin's lymphoma. Blood 2008;111:5359-70
    • (2008) Blood , vol.111 , pp. 5359-5370
    • Mittal, S.1    Marshall, N.A.2    Duncan, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.