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Volumn 69, Issue 11, 2008, Pages 811-814

CD8+ regulatory T cells, their suppressive mechanisms, and regulation in cancer

Author keywords

Immune suppression; Regulatory T cells; Tumor immunity; Tumor microenvironment

Indexed keywords

INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 2 RECEPTOR BETA; INTERLEUKIN 7 RECEPTOR; T LYMPHOCYTE RECEPTOR; TOLL LIKE RECEPTOR 8; TRANSCRIPTION FACTOR FOXP3;

EID: 57649101649     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2008.08.276     Document Type: Article
Times cited : (74)

References (62)
  • 1
    • 0035902080 scopus 로고    scopus 로고
    • Progress in human tumour immunology and immunotherapy
    • Rosenberg S.A. Progress in human tumour immunology and immunotherapy. Nature 411 (2001) 380-384
    • (2001) Nature , vol.411 , pp. 380-384
    • Rosenberg, S.A.1
  • 2
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • Dunn G.P., Old L.J., and Schreiber R.D. The immunobiology of cancer immunosurveillance and immunoediting. Immunity 21 (2004) 137-148
    • (2004) Immunity , vol.21 , pp. 137-148
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 3
    • 0036812676 scopus 로고    scopus 로고
    • Enhancing antitumor immune responses: intracellular peptide delivery and identification of MHC class II-restricted tumor antigens
    • Wang R.F. Enhancing antitumor immune responses: intracellular peptide delivery and identification of MHC class II-restricted tumor antigens. Immunol Rev 188 (2002) 65-80
    • (2002) Immunol Rev , vol.188 , pp. 65-80
    • Wang, R.F.1
  • 5
    • 33847647528 scopus 로고    scopus 로고
    • Regulatory T cells and cancer
    • Wang H.Y., and Wang R.F. Regulatory T cells and cancer. Curr Opin Immunol 19 (2007) 217-223
    • (2007) Curr Opin Immunol , vol.19 , pp. 217-223
    • Wang, H.Y.1    Wang, R.F.2
  • 6
    • 2442484053 scopus 로고    scopus 로고
    • + regulatory T cells for immunologic self-tolerance and negative control of immune responses
    • + regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 22 (2004) 531-562
    • (2004) Annu Rev Immunol , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 7
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor foxp3
    • Hori S., Nomura T., and Sakaguchi S. Control of regulatory T cell development by the transcription factor foxp3. Science 299 (2003) 1057-1061
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 8
    • 0037385314 scopus 로고    scopus 로고
    • An essential role for Scurfin in CD4(+)CD25(+) T regulatory cells
    • Khattri R., Cox T., Yasayko S.A., and Ramsdell F. An essential role for Scurfin in CD4(+)CD25(+) T regulatory cells. Nat Immunol 4 (2003) 337-342
    • (2003) Nat Immunol , vol.4 , pp. 337-342
    • Khattri, R.1    Cox, T.2    Yasayko, S.A.3    Ramsdell, F.4
  • 9
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4(+)CD25(+) regulatory T cells
    • Fontenot J.D., Gavin M.A., and Rudensky A.Y. Foxp3 programs the development and function of CD4(+)CD25(+) regulatory T cells. Nat Immunol 4 (2003) 330-336
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 13
    • 33745813929 scopus 로고    scopus 로고
    • Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
    • Seddiki N., Santner-Nanan B., Martinson J., Zaunders J., Sasson S., Landay A., et al. Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J Exp Med 203 (2006) 1693-1700
    • (2006) J Exp Med , vol.203 , pp. 1693-1700
    • Seddiki, N.1    Santner-Nanan, B.2    Martinson, J.3    Zaunders, J.4    Sasson, S.5    Landay, A.6
  • 16
    • 0035186416 scopus 로고    scopus 로고
    • Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells
    • Weiner H.L. Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells. Immunol Rev 182 (2001) 207-214
    • (2001) Immunol Rev , vol.182 , pp. 207-214
    • Weiner, H.L.1
  • 18
    • 85047690488 scopus 로고    scopus 로고
    • An integrated view of suppressor T cell subsets in immunoregulation
    • Jiang H., and Chess L. An integrated view of suppressor T cell subsets in immunoregulation. J Clin Invest 114 (2004) 1198-1208
    • (2004) J Clin Invest , vol.114 , pp. 1198-1208
    • Jiang, H.1    Chess, L.2
  • 19
    • 0034747056 scopus 로고    scopus 로고
    • - T suppressor cells and the induction of antigen-specific, antigen-presenting cell-mediated suppression of Th reactivity
    • - T suppressor cells and the induction of antigen-specific, antigen-presenting cell-mediated suppression of Th reactivity. Immunol Rev 182 (2001) 201-206
    • (2001) Immunol Rev , vol.182 , pp. 201-206
    • Cortesini, R.1    LeMaoult, J.2    Ciubotariu, R.3    Cortesini, N.S.4
  • 20
    • 0038612760 scopus 로고    scopus 로고
    • + T suppressor cells are back to the game: are they players in autoimmunity?
    • + T suppressor cells are back to the game: are they players in autoimmunity?. Autoimmun Rev 1 (2002) 279-283
    • (2002) Autoimmun Rev , vol.1 , pp. 279-283
    • Filaci, G.1    Suciu-Foca, N.2
  • 22
    • 36048951446 scopus 로고    scopus 로고
    • Central role of ILT3 in the T suppressor cell cascade
    • Suciu-Foca N., and Cortesini R. Central role of ILT3 in the T suppressor cell cascade. Cell Immunol 248 (2007) 59-67
    • (2007) Cell Immunol , vol.248 , pp. 59-67
    • Suciu-Foca, N.1    Cortesini, R.2
  • 29
    • 34548024379 scopus 로고    scopus 로고
    • Tumor-infiltrating gamma-delta T cells suppress T and dendritic cell function via mechanisms controlled by a unique Toll-like receptor signaling pathway
    • Peng G., Wang H.Y., Peng W., Kiniwa Y., Seo K., and Wang R.-F. Tumor-infiltrating gamma-delta T cells suppress T and dendritic cell function via mechanisms controlled by a unique Toll-like receptor signaling pathway. Immunity 27 (2007) 334-348
    • (2007) Immunity , vol.27 , pp. 334-348
    • Peng, G.1    Wang, H.Y.2    Peng, W.3    Kiniwa, Y.4    Seo, K.5    Wang, R.-F.6
  • 31
    • 0041422186 scopus 로고    scopus 로고
    • Alpha-galactosylceramide (KRN7000) suppression of chemical- and oncogene-dependent carcinogenesis
    • Hayakawa Y., Rovero S., Forni G., and Smyth M.J. Alpha-galactosylceramide (KRN7000) suppression of chemical- and oncogene-dependent carcinogenesis. Proc Natl Acad Sci USA 100 (2003) 9464-9469
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 9464-9469
    • Hayakawa, Y.1    Rovero, S.2    Forni, G.3    Smyth, M.J.4
  • 32
    • 0037787982 scopus 로고    scopus 로고
    • Activation of natural killer T cells by alpha-galactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein
    • Fujii S., Shimizu K., Smith C., Bonifaz L., and Steinman R.M. Activation of natural killer T cells by alpha-galactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein. J Exp Med 198 (2003) 267-279
    • (2003) J Exp Med , vol.198 , pp. 267-279
    • Fujii, S.1    Shimizu, K.2    Smith, C.3    Bonifaz, L.4    Steinman, R.M.5
  • 33
    • 28544431840 scopus 로고    scopus 로고
    • Innate NKT lymphocytes confer superior adaptive immunity via tumor-capturing dendritic cells
    • Liu K., Idoyaga J., Charalambous A., Fujii S., Bonito A., Mordoh J., et al. Innate NKT lymphocytes confer superior adaptive immunity via tumor-capturing dendritic cells. J Exp Med 202 (2005) 1507-1516
    • (2005) J Exp Med , vol.202 , pp. 1507-1516
    • Liu, K.1    Idoyaga, J.2    Charalambous, A.3    Fujii, S.4    Bonito, A.5    Mordoh, J.6
  • 34
    • 0034569025 scopus 로고    scopus 로고
    • NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway
    • Terabe M., Matsui S., Noben-Trauth N., Chen H., Watson C., Donaldson D.D., et al. NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway. Nat Immunol 1 (2000) 515-520
    • (2000) Nat Immunol , vol.1 , pp. 515-520
    • Terabe, M.1    Matsui, S.2    Noben-Trauth, N.3    Chen, H.4    Watson, C.5    Donaldson, D.D.6
  • 35
    • 0034569294 scopus 로고    scopus 로고
    • Immune suppression and skin cancer development: regulation by NKT cells
    • Moodycliffe A.M., Nghiem D., Clydesdale G., and Ullrich S.E. Immune suppression and skin cancer development: regulation by NKT cells. Nat Immunol 1 (2000) 521-525
    • (2000) Nat Immunol , vol.1 , pp. 521-525
    • Moodycliffe, A.M.1    Nghiem, D.2    Clydesdale, G.3    Ullrich, S.E.4
  • 36
    • 10744220561 scopus 로고    scopus 로고
    • Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence
    • Terabe M., Matsui S., Park J.M., Mamura M., Noben-Trauth N., et al. Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence. J Exp Med 198 (2003) 1741-1752
    • (2003) J Exp Med , vol.198 , pp. 1741-1752
    • Terabe, M.1    Matsui, S.2    Park, J.M.3    Mamura, M.4    Noben-Trauth, N.5
  • 37
    • 29144484782 scopus 로고    scopus 로고
    • A nonclassical non-Valpha14Jalpha18 CD1d-restricted (type II) NKT cell is sufficient for down-regulation of tumor immunosurveillance
    • Terabe M., Swann J., Ambrosino E., Sinha P., Takaku S., Hayakawa Y., et al. A nonclassical non-Valpha14Jalpha18 CD1d-restricted (type II) NKT cell is sufficient for down-regulation of tumor immunosurveillance. J Exp Med 202 (2005) 1627-1633
    • (2005) J Exp Med , vol.202 , pp. 1627-1633
    • Terabe, M.1    Swann, J.2    Ambrosino, E.3    Sinha, P.4    Takaku, S.5    Hayakawa, Y.6
  • 38
    • 33746599842 scopus 로고    scopus 로고
    • Regulatory T cells in cancer
    • Beyer M., and Schultze J.L. Regulatory T cells in cancer. Blood 108 (2006) 804-811
    • (2006) Blood , vol.108 , pp. 804-811
    • Beyer, M.1    Schultze, J.L.2
  • 39
    • 43449101175 scopus 로고    scopus 로고
    • Tumor-specific regulatory T cells in cancer patients
    • Piersma S.J., Welters M.J., and van der Burg S.H. Tumor-specific regulatory T cells in cancer patients. Hum Immunol 69 (2008) 241-249
    • (2008) Hum Immunol , vol.69 , pp. 241-249
    • Piersma, S.J.1    Welters, M.J.2    van der Burg, S.H.3
  • 44
    • 0037128654 scopus 로고    scopus 로고
    • Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells
    • Gilliet M., and Liu Y.J. Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells. J Exp Med 195 (2002) 695
    • (2002) J Exp Med , vol.195 , pp. 695
    • Gilliet, M.1    Liu, Y.J.2
  • 47
    • 41549159660 scopus 로고    scopus 로고
    • Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces
    • Rubtsov Y.P., Rasmussen J.P., Chi E.Y., Fontenot J., Castelli L., Ye X., et al. Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces. Immunity 28 (2008) 546-558
    • (2008) Immunity , vol.28 , pp. 546-558
    • Rubtsov, Y.P.1    Rasmussen, J.P.2    Chi, E.Y.3    Fontenot, J.4    Castelli, L.5    Ye, X.6
  • 48
    • 34248592104 scopus 로고    scopus 로고
    • T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation
    • Li M.O., Wan Y.Y., and Flavell R.A. T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation. Immunity 26 (2007) 579-591
    • (2007) Immunity , vol.26 , pp. 579-591
    • Li, M.O.1    Wan, Y.Y.2    Flavell, R.A.3
  • 49
    • 36549030784 scopus 로고    scopus 로고
    • The inhibitory cytokine IL-35 contributes to regulatory T-cell function
    • Collison L.W., Workman C.J., Kuo T.T., Boyd K., Wang Y., Vignali K.M., et al. The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature 450 (2007) 566-569
    • (2007) Nature , vol.450 , pp. 566-569
    • Collison, L.W.1    Workman, C.J.2    Kuo, T.T.3    Boyd, K.4    Wang, Y.5    Vignali, K.M.6
  • 51
    • 5644302161 scopus 로고    scopus 로고
    • Human T regulatory cells can use the perforin pathway to cause autologous target cell death
    • Grossman W.J., Verbsky J.W., Barchet W., Colonna M., Atkinson J.P., and Ley T.J. Human T regulatory cells can use the perforin pathway to cause autologous target cell death. Immunity 21 (2004) 589-601
    • (2004) Immunity , vol.21 , pp. 589-601
    • Grossman, W.J.1    Verbsky, J.W.2    Barchet, W.3    Colonna, M.4    Atkinson, J.P.5    Ley, T.J.6
  • 53
    • 36248976097 scopus 로고    scopus 로고
    • CD4(+)CD25(+)Foxp3(+) regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4(+) T cells
    • Pandiyan P., Zheng L., Ishihara S., Reed J., and Lenardo M.J. CD4(+)CD25(+)Foxp3(+) regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4(+) T cells. Nat Immunol 8 (2007) 1353-1362
    • (2007) Nat Immunol , vol.8 , pp. 1353-1362
    • Pandiyan, P.1    Zheng, L.2    Ishihara, S.3    Reed, J.4    Lenardo, M.J.5
  • 55
    • 34250351459 scopus 로고    scopus 로고
    • Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
    • Deaglio S., Dwyer K.M., Gao W., Friedman D., Usheva A., and Erat A. Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J Exp Med 204 (2007) 1257-1265
    • (2007) J Exp Med , vol.204 , pp. 1257-1265
    • Deaglio, S.1    Dwyer, K.M.2    Gao, W.3    Friedman, D.4    Usheva, A.5    Erat, A.6
  • 56
    • 27444435581 scopus 로고    scopus 로고
    • Inability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma
    • Attia P., Maker A.V., Haworth L.R., Rogers-Freezer L., and Rosenberg S.A. Inability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma. J Immunother 28 (2005) 582-592
    • (2005) J Immunother , vol.28 , pp. 582-592
    • Attia, P.1    Maker, A.V.2    Haworth, L.R.3    Rogers-Freezer, L.4    Rosenberg, S.A.5
  • 57
    • 30144444279 scopus 로고    scopus 로고
    • Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells
    • Dannull J., Su Z., Rizzieri D., Yang B.K., Coleman D., Yancey D., et al. Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells. J Clin Invest 115 (2005) 3623-3633
    • (2005) J Clin Invest , vol.115 , pp. 3623-3633
    • Dannull, J.1    Su, Z.2    Rizzieri, D.3    Yang, B.K.4    Coleman, D.5    Yancey, D.6
  • 58
    • 0037436119 scopus 로고    scopus 로고
    • Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells
    • Pasare C., and Medzhitov R. Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science 299 (2003) 1033-1036
    • (2003) Science , vol.299 , pp. 1033-1036
    • Pasare, C.1    Medzhitov, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.