CD8+ T suppressor cells are back to the game: Are they players in autoimmunity?

Autoimmunity Reviews

Volumn 1, Issue 5, 2002, Pages 279-283

  Filaci, Gilberto ^a,b   Suciu Foca, Nicole ^c  

^a UNIVERSITY OF GENOA   (Italy)

^b Center of Excellence for Biomedical Research   (Italy)

^c Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

CD8+ T suppressor cells; Immune regulation; Immune tolerance

Indexed keywords

ANTIGEN; CD8 ANTIGEN; CYTOKINE;

ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; AUTOIMMUNITY; CELL INTERACTION; CYTOKINE RELEASE; DENDRITIC CELL; HUMAN; IMMUNE MEDIATED INJURY; LYMPHOCYTE PROLIFERATION; REVIEW; SUPPRESSOR CELL; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; TH2 CELL; ANIMAL; BIOLOGICAL MODEL; CLASSIFICATION; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MOUSE; PHENOTYPE; REGULATORY T LYMPHOCYTE;

ANIMALS; AUTOIMMUNITY; DENDRITIC CELLS; HUMANS; IMMUNE TOLERANCE; LYMPHOCYTE ACTIVATION; MICE; MODELS, IMMUNOLOGICAL; PHENOTYPE; T-LYMPHOCYTES, REGULATORY;

EID: 0038612760     PISSN: 15689972     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1568-9972(02)00065-4     Document Type: Review

References (19)

1. Dieckmann D., Plottner H., Berchtold S., Berger T., Schuler G. Ex vivo isolation and characterization of cd4(+)cd25(+) t cells with regulatory properties from human blood. J Exp Med. 193:2001;1303-1310.
2. Jonuleit H., Schmitt E., Stassen M., Tuettenberg A., Knop J., Enk A.K. Identification and functional characterization of human cd4(+)cd25(+) t cells with regulatory properties isolated from peripheral blood. J Exp Med. 193:2001;1285-1294.
3. Banchereau J., Steinman R.M. Dendritic cells and the control of immunity. Nature. 392:1998;245-252.
4. Pulendran B., Maraskovsky E., Banchereau J., Maliszewski C. Trends Immunol. 22:2001;41-47.
5. Gershon R.K., Kondo K. Infectious immunological tolerance. Immunology. 21:1971;903-913.
6. Damle N.K., Engleman E.G. Antigen-specific suppressor T lymphocytes in man. Clin Immunol Immunopathol. 53:1989;S17-S24.
7. Sercarz E., Krzych U. The distinctive specificity of antigen-specific suppressor T cells. Immunol Today. 12:1991;111-118.
8. + cells in myasthenia gravis patients and in healthy controls. J Immunol. 154:1995;1508-1520.
9. Sun D., Qin Y., Chluba J., Epplen J.T., Wekerle H. Suppression of experimentally induced autoimmune encephalomyelitis by cytolytic T-T cell interactions. Nature. 332:1988;843-845.
10. - T cells. Int Immunol. 10:1998;775-783.
11. + T suppressor cell function in patients with active systemic lupus erythematosus. J Immunol. 166:2001;6452-6457.
12. - regulatory T cells. J Immunol. 161:1998;5193-5202.
13. Jiang S., Tugulea S., Pennesi G., et al. Induction of MHC-class I restricted human suppressor T cells by peptide priming in vitro. Hum Immunol. 59:1998;690-699.
14. - T cells. Transplantation. 69:2000;1304-1310.
15. Liu Z., Tugulea S., Cortesini R., Lederman S., Suciu-Foca N. Inhibition of CD40 signaling pathway in antigen presenting cells by T suppressor cells. Hum Immunol. 60:1999;568-574.
16. Chang C.C., Ciubotariu R., Manavalan J.S., et al. Tolerization of dendritic cells by Ts cells: the crucial role of inhibitory receptors ILT3 and ILT4. Nat Immunol. 3:2002;237-243.
17. Ciubotariu R., Vasilescu R., Ho E., et al. Detection of T suppressor cells in patients with organ allografts. Hum Immunol. 62:2001;15-20.
18. + T cells is mediated by interferon-γ and is defective in chronic progressive multiple sclerosis. J Clin Invest. 95:1995;2711-2719.
19. Gilliet M., Liu Y.-J. Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells. J Exp Med. 195:2002;695-704.