-
1
-
-
33746310315
-
Alzheimer's disease
-
BLENNOW K., DE LEON M.J. -Alzheimer's disease. The Lancet, 2007, 368, 387-403.
-
(2007)
The Lancet
, vol.368
, pp. 387-403
-
-
Blennow, K.1
De Leon, M.J.2
-
2
-
-
33750582961
-
Therapeutic approaches to Alzheimer's disease
-
KLAFKI H.W., STAUFENBIEL M., KORNHUBER J., WiLTFANG J. -Therapeutic approaches to Alzheimer's disease. Brain, 2006, 129, 2840-55.
-
(2006)
Brain
, vol.129
, pp. 2840-2855
-
-
Klafki, H.W.1
Staufenbiel, M.2
Kornhuber, J.3
Wiltfang, J.4
-
3
-
-
66049154498
-
Perspectives of Alzheimer'disease treatments
-
Dementias, Eds C Duyckaerts et I Litvan, Elsevier BV, sous presse
-
DAVIS J.B., BOUNTRA C., RICHARDSON J. -Perspectives of Alzheimer'disease treatments. In : Dementias, Handbook of Clinical Neurology, Vol.89, Eds C Duyckaerts et I Litvan, Elsevier BV, sous presse.
-
Handbook of Clinical Neurology
, vol.89
-
-
Davis, J.B.1
Bountra, C.2
Richardson, J.3
-
4
-
-
33750339228
-
A network dysfunction perspective on neurodegenerative diseases
-
PALOP JJ., CHIN J., MUCKE L. -A network dysfunction perspective on neurodegenerative diseases. Nature. 2006, 443, 768-773
-
(2006)
Nature
, vol.443
, pp. 768-773
-
-
Palop, J.J.1
Chin, J.2
Mucke, L.3
-
5
-
-
33746924088
-
Neurogénèse adulte: Aspects fondamentaux et potentiels thérapeutiques
-
LLEDO P.M., GHEUSI G. -Neurogénèse adulte : aspects fondamentaux et potentiels thérapeutiques. Bull Acad Natl Med. 2006, 190, 385-400.
-
(2006)
Bull Acad Natl Med.
, vol.190
, pp. 385-400
-
-
Lledo, P.M.1
Gheusi, G.2
-
7
-
-
3242803587
-
Nonsteroidal anti-inflammatory drugs for the prevention of Alzheimer's disease: A systematic review
-
SZEKELY C.A., THORNE J.E., ZANDI P.P. -Nonsteroidal anti-inflammatory drugs for the prevention of Alzheimer's disease : a systematic review. Neuroepidemiology, 2004, 23, 159-169
-
(2004)
Neuroepidemiology
, vol.23
, pp. 159-169
-
-
Szekely, C.A.1
Thorne, J.E.2
Zandi, P.P.3
-
8
-
-
33745921486
-
Meta-analysis: Cardiovascular events associated with nonsteroidal anti-inflammatory drugs
-
SALPETER S.R, GREGOR P., ORMISTON T.M., WHITLOCK R., RAINA P., THABANE L., TOPOL EJ. - Meta-analysis : cardiovascular events associated with nonsteroidal anti-inflammatory drugs. Am J Med. 2006; 119: 552-559
-
(2006)
Am J Med.
, vol.119
, pp. 552-559
-
-
Salpeter, S.R.1
Gregor, P.2
Ormiston, T.M.3
Whitlock, R.4
Raina, P.5
Thabane, L.6
Topol, E.J.7
-
9
-
-
0037638809
-
Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: A randomized controlled trial
-
AISEN P.S., SCHÄFER K. A., GRUNDMAN M. et al. -Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression : a randomized controlled trial. JAMA, 2003,289,2819-26.
-
(2003)
JAMA
, vol.289
, pp. 2819-2826
-
-
Aisen, P.S.1
Schäfer, K.A.2
Grundman, M.3
-
10
-
-
0034638746
-
Statins and the risk of dementia
-
JICK H., ZORNBERG G.L., JICK S.S., SESHADRI S., DRACHMAN D.A. -Statins and the risk of dementia. Lancet, 2000, 356, 1627-1631
-
(2000)
Lancet
, vol.356
, pp. 1627-1631
-
-
Jick, H.1
Zornberg, G.L.2
Jick, S.S.3
Seshadri, S.4
Drachman, D.A.5
-
11
-
-
0347318065
-
Cholesterol and the biology of Alzheimer's disease
-
WOLOZIN B. -Cholesterol and the biology of Alzheimer's disease. Neuron, 2004, 41, 7-10.
-
(2004)
Neuron
, vol.41
, pp. 7-10
-
-
Wolozin, B.1
-
12
-
-
34548291482
-
Statin therapy is associated with reduced neuropathologic changes of Alzheimer disease
-
Li G., LARSON E.B., SONNEN J.A., SHOFER J.B., PÉTRIE B.C., SCHANTZ A. et al.-Statin therapy is associated with reduced neuropathologic changes of Alzheimer disease Neurology, 2007,69, 878-885.
-
(2007)
Neurology
, vol.69
, pp. 878-885
-
-
Li, G.1
Larson, E.B.2
Sonnen, J.A.3
Shofer, J.B.4
Pétrie, B.C.5
Schantz, A.6
-
13
-
-
0033833354
-
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model
-
REFOLO L., MALESTER B., LAFRANCOIS J., BRYANT-THOMAS T., WANG R. et coll. -Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model. Neurobiol. Dis., 2000, 7, 321-331.
-
(2000)
Neurobiol. Dis.
, vol.7
, pp. 321-331
-
-
Refolo, L.1
Malester, B.2
Lafrancois, J.3
Bryant-Thomas, T.4
Wang, R.5
-
14
-
-
0037164314
-
Pravastatin in elderly individuals at risk of vascular disease (PROSPER): A randomised controlled trial
-
SHEPERD J., BLAUW G.J., MURPHY M.B. et al. -Pravastatin in elderly individuals at risk of vascular disease (PROSPER) : a randomised controlled trial. Lancet, 2000, 360, 1623-1630
-
(2000)
Lancet
, vol.360
, pp. 1623-1630
-
-
Sheperd, J.1
Blauw, G.J.2
Murphy, M.B.3
-
15
-
-
0037031061
-
MRC/BHF. Heart protection Study of cholesterol lowering with simvastatin in 20536 high risk individuals: A randomised placebocontrolled trial
-
Heart Protection Study Collaborative Group (2002)
-
Heart Protection Study Collaborative Group (2002) MRC/BHF. Heart protection Study of cholesterol lowering with simvastatin in 20536 high risk individuals : a randomised placebocontrolled trial. Lancet, 2002, 360, 7-22.
-
(2002)
Lancet
, vol.360
, pp. 7-22
-
-
-
16
-
-
8644239495
-
Statin therapy and risk of dementia in the elderly: A community-based prospective cohort study
-
Li G., HIGDON R., KUKULL W.A. et al. -Statin therapy and risk of dementia in the elderly : a community-based prospective cohort study. Neurology, 2004, 63, 1624-1628
-
(2004)
Neurology
, vol.63
, pp. 1624-1628
-
-
Li, G.1
Higdon, R.2
Kukull, W.A.3
-
17
-
-
33745759330
-
Re-assessing the relationship between cholesterol, statins and Alzheimer's disease
-
WOLOZIN B., MANGER J., BRYANT R., CORDY J., GREEN R.C., MCKEE A. -Re-assessing the relationship between cholesterol, statins and Alzheimer's disease. Acta. Neurol. Scand. Suppl. 2006, 185, 63-70.
-
(2006)
Acta. Neurol. Scand. Suppl.
, vol.185
, pp. 63-70
-
-
Wolozin, B.1
Manger, J.2
Bryant, R.3
Cordy, J.4
Green, R.C.5
Mckee, A.6
-
18
-
-
0035925762
-
Hormone Replacement therapy and cognition. Systematic review and meta-analysis
-
LEBLANC E.S., JANOWSKY J., CHAN B.K., NELSON H.D. -Hormone Replacement therapy and cognition. Systematic review and meta-analysis. JAMA, 2001, 285,1489-1499
-
(2001)
JAMA
, vol.285
, pp. 1489-1499
-
-
Leblanc, E.S.1
Janowsky, J.2
Chan, B.K.3
Nelson, H.D.4
-
19
-
-
70249121973
-
Hormone replacement therapy to maintain cognitive function in women with dementia. Cochrane database
-
HOGERVORST E., YAFFE K., RICHARDS M., HUPPERT F. -Hormone replacement therapy to maintain cognitive function in women with dementia. Cochrane database Syst. Rev. 2002, 3, CD003799.
-
(2002)
Syst. Rev.
, vol.3
-
-
Hogervorst, E.1
Yaffe, K.2
Richards, M.3
Huppert, F.4
-
20
-
-
34948829010
-
Increased risk of cognitive impairment or dementia in women who underwent oophorectomy before menopause
-
ROCCA W.A., BOWER J.H., MARAGANORE D.M., AHLSKOG J.E., GROSSARDT B.R., DE ANDRADE M., MELTON L.H. -Increased risk of cognitive impairment or dementia in women who underwent oophorectomy before menopause. Neurology, 2007, 69, 1074-1083.
-
(2007)
Neurology
, vol.69
, pp. 1074-1083
-
-
Rocca, W.A.1
Bower, J.H.2
Maraganore, D.M.3
Ahlskog, J.E.4
Grossardt, B.R.5
De Andrade, M.6
Melton, L.H.7
-
21
-
-
0034704547
-
Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: A randomized controlled trial. Alzheimer's Disease Cooperative Study
-
MULNARD R.A., COTMAN C.W., KULLER I. et al. -Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease : a randomized controlled trial. Alzheimer's Disease Cooperative Study. JAMA, 2000, 283, 1007-1015
-
(2000)
JAMA
, vol.283
, pp. 1007-1015
-
-
Mulnard, R.A.1
Cotman, C.W.2
Kuller, I.3
-
22
-
-
2942755831
-
Conjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women: Women Health Initiative Memory Study
-
SHUMAKER S.A., LEGAULT C., KULLER L. et al.-Conjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women : Women Health Initiative Memory Study. JAMA, 2004, 291, 2947-2958
-
(2004)
JAMA
, vol.291
, pp. 2947-2958
-
-
Shumaker, S.A.1
Legault, C.2
Kuller, L.3
-
23
-
-
0037178573
-
Dietary intake of antioxydants and risk of Alzheimer disease
-
ENGELHART MJ., GEERLINGS M.I., RUITENBERG A. et al.-Dietary intake of antioxydants and risk of Alzheimer disease. JAMA, 2004, 287, 3223-3229
-
(2004)
JAMA
, vol.287
, pp. 3223-3229
-
-
Engelhart, M.J.1
Geerlings, M.I.2
Ruitenberg, A.3
-
24
-
-
0037178579
-
Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study
-
MORRIS M.C., EVANS D.A., BIENIAS J.L. et al.-Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study. JAMA, 2002, 287, 3230-3237
-
(2002)
JAMA
, vol.287
, pp. 3230-3237
-
-
Morris, M.C.1
Evans, D.A.2
Bienias, J.L.3
-
25
-
-
0030967165
-
A controlled trial of selegiline, alpha-tocopherol or both as a treatment for Alzheimer's disease
-
SANO M., ERNESTO C., THOMAS R.G. et al. -A controlled trial of selegiline, alpha-tocopherol or both as a treatment for Alzheimer's disease. N. Eng. J. Med., 1997, 336, 1216-1222
-
(1997)
N. Eng. J. Med.
, vol.336
, pp. 1216-1222
-
-
Sano, M.1
Ernesto, C.2
Thomas, R.G.3
-
26
-
-
20344381835
-
Vitamin E and donezepil for the treatment of mild cognitive impairment
-
PETERSEN R.G, THOMAS R.G., GRUNDMAN M. et al. -Vitamin E and donezepil for the treatment of mild cognitive impairment. N Eng. J. Med., 2005, 352, 2379-2388
-
(2005)
N Eng. J. Med.
, vol.352
, pp. 2379-2388
-
-
Petersen, R.G.1
Thomas, R.G.2
Grundman, M.3
-
27
-
-
0030003819
-
15-Year longitudinal study of blood pressure and dementia
-
SKOOG I., LERNFELT B., LANDAHL S. et al. -15-year longitudinal study of blood pressure and dementia. Lancet, 1996, 347, 1141-1145
-
(1996)
Lancet
, vol.347
, pp. 1141-1145
-
-
Skoog, I.1
Lernfelt, B.2
Landahl, S.3
-
28
-
-
1542780835
-
Hypertension and dementia
-
HANON O., SEUX M.L, LENOIR H., RIGAUD A.S., FORETTE F. -Hypertension and dementia. Curr. Cardiol. Rep., 2003, 6, 435-440
-
(2003)
Curr. Cardiol. Rep.
, vol.6
, pp. 435-440
-
-
Hanon, O.1
Seux, M.L.2
Lenoir, H.3
Rigaud, A.S.4
Forette, F.5
-
29
-
-
0032564132
-
Prevention of dementia in randomised double-blind placebo-controlled Systolic Hypertension in Europe (Syst-eur) trial
-
FORETTE F., SEUX M.L., STAESSEN J.A. et al. -Prevention of dementia in randomised double-blind placebo-controlled Systolic Hypertension in Europe (Syst-Eur) trial. Lancet, 1998, 552, 1347-1351
-
(1998)
Lancet
, vol.552
, pp. 1347-1351
-
-
Forette, F.1
Seux, M.L.2
Staessen, J.A.3
-
30
-
-
0037078312
-
The prevention of dementia with antihypertensive treatment: New evidence from the Systolic Hypertension in Europe (Syst-eur) study
-
FORETTE F., SEUX M.L., STAESSEN J. et al.-The prevention of dementia with antihypertensive treatment : new evidence from the Systolic Hypertension in Europe (Syst-eur) study. Arch. Int. Med., 2002, 162, 2046-2052
-
(2002)
Arch. Int. Med.
, vol.162
, pp. 2046-2052
-
-
Forette, F.1
Seux, M.L.2
Staessen, J.3
-
31
-
-
0038669268
-
Effects of blood pressure lowering with Perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease
-
PROGRESS Collaborative Group
-
TZOURIO C., ANDERSON C., CHAPMAN N. et al. -PROGRESS Collaborative Group. Effects of blood pressure lowering with Perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease. Arch. Intern. Med., 2003, 163, 1069-1075
-
(2003)
Arch. Intern. Med.
, vol.163
, pp. 1069-1075
-
-
Tzourio, C.1
Anderson, C.2
Chapman, N.3
-
32
-
-
0035931293
-
Blood pressure, cognitive functions, and prevention of dementia in older patients with hypertension
-
BIRKENHEGER W.H., FORETTE F., SEUX M.L. et al. -Blood pressure, cognitive functions, and prevention of dementia in older patients with hypertension. Arch. Int. Med. 2002, 161, 152.
-
(2002)
Arch. Int. Med.
, vol.161
, pp. 152
-
-
Birkenheger, W.H.1
Forette, F.2
Seux, M.L.3
-
33
-
-
33748543254
-
Relationship between antihypertensive drug therapy and cognitive function in elderly hypertensive patients with memory complaints
-
HANON O., PÉQUIGNOT R., SEUX M.L. et al. -Relationship between antihypertensive drug therapy and cognitive function in elderly hypertensive patients with memory complaints. J. Hypertens., 2006, 1, 2101-2107
-
(2006)
J. Hypertens.
, vol.1
, pp. 2101-2107
-
-
Hanon, O.1
Péquignot, R.2
Seux, M.L.3
-
34
-
-
0038115068
-
Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease
-
MORRIS M.C., EVANS D.A., BIENIAS J.L. et al. -Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease. Arch. Neurol., 2003, 60, 940-946
-
(2003)
Arch. Neurol.
, vol.60
, pp. 940-946
-
-
Morris, M.C.1
Evans, D.A.2
Bienias, J.L.3
-
35
-
-
34548656056
-
Alpérovitch A dietary pattern and risk of dementia. The Three-City cohort study
-
BABERGER-GATEAU P., RAFFAITIN C., LETENNEUR L., BERR C., TZOURIO C., DARTIGUES J.F. - Alpérovitch A Dietary pattern and risk of dementia. The Three-City cohort study. Neurology, 2007, 69, 1921-1930.
-
(2007)
Neurology
, vol.69
, pp. 1921-1930
-
-
Baberger-Gateau, P.1
Raffaitin, C.2
Letenneur, L.3
Berr, C.4
Tzourio, C.5
Dartigues, J.F.6
-
36
-
-
0037392130
-
Fitness and cognition: Encouraging findings and methodological considerations for future work
-
SIMONSICK E.M. -Fitness and cognition : encouraging findings and methodological considerations for future work. J. Am. Geriatr. Soc., 2003, 51, 570-571
-
(2003)
J. Am. Geriatr. Soc.
, vol.51
, pp. 570-571
-
-
Simonsick, E.M.1
-
37
-
-
0038130715
-
Leisure activities and the risk of dementia in the elderly
-
VERGHESE J., LIPTON R.B., KATZ M.J. et al. -Leisure activities and the risk of dementia in the elderly. N. Engl. J. Med, 348, 2508-2516
-
N. Engl. J. Med
, vol.348
, pp. 2508-2516
-
-
Verghese, J.1
Lipton, R.B.2
Katz, M.J.3
-
38
-
-
0038130760
-
Use it or lose it - Do effortful mental activities protect against dementia?
-
COYLE J.T -Use it or lose it -Do effortful mental activities protect against dementia ? Ai Engl. J. Med., 2003, 348, 2489-2490
-
(2003)
Ai Engl. J. Med.
, vol.348
, pp. 2489-2490
-
-
Coyle, J.T.1
-
39
-
-
0035116273
-
Mice deficient in BACE1, the Alzheimer beta-secretase, have normal phénotype and abolished beta-amylo'id generation
-
Luo Y., BOLON B., KAHN S. et al. -Mice deficient in BACE1, The Alzheimer beta-secretase, have normal phénotype and abolished beta-amylo'id generation. Nat. Neurosci., 2001, 4, 231-232
-
(2001)
Nat. Neurosci.
, vol.4
, pp. 231-232
-
-
Luo, Y.1
Bolon, B.2
Kahn, S.3
-
40
-
-
33846261909
-
Oral administration of a potent and selective non peptidic BACE1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid beta production in vivo
-
HUSSAIN I., HAWKINS J., HARRISON D. et al. -Oral administration of a potent and selective non peptidic BACE1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid beta production in vivo. J. neurochem., 2007, 100, 802-809
-
(2007)
J. Neurochem.
, vol.100
, pp. 802-809
-
-
Hussain, I.1
Hawkins, J.2
Harrison, D.3
-
42
-
-
33847711478
-
Disease-modifying therapies in Alzheimer's disease: How far have we come?
-
HULL M., BERGER M., HENEKA M. -Disease-modifying therapies in Alzheimer's disease : how far have we come ? Drugs, 2006, 66, 2075-2093
-
(2006)
Drugs
, vol.66
, pp. 2075-2093
-
-
Hull, M.1
Berger, M.2
Heneka, M.3
-
43
-
-
33646787103
-
Inhibition of gamma-secretase as a therapeutic intervention for Alzheimer's disease: Propescts, limitations and strategies
-
EVIN G., SERNEE M.F., MASTERS C.L. -Inhibition of gamma-secretase as a therapeutic intervention for Alzheimer's disease : propescts, limitations and strategies. CNS Drugs, 2006, 20, 351-372
-
(2006)
CNS Drugs
, vol.20
, pp. 351-372
-
-
Evin, G.1
Sernee, M.F.2
Masters, C.L.3
-
44
-
-
0035005101
-
New protease inhibitors prevent gamma-secretase production of Abeta 40/42 without affecting Notch cleavage
-
PETIT A., BIHEL F., ALVES DA COSTA C., POURQUIE O., CHECLER F., KRAUS JL.-New protease inhibitors prevent gamma-secretase production of Abeta 40/42 without affecting Notch cleavage. Nat. Cell. Biol., 3, 507-511
-
Nat. Cell. Biol.
, vol.3
, pp. 507-511
-
-
Petit, A.1
Bihel, F.2
Alves Da Costa, C.3
Pourquie, O.4
Checler, F.5
Kraus, J.L.6
-
45
-
-
21544458621
-
Safety, tolerability, and changes in amyloid beta concentration after administration of a gamma-secretase inhibitor in volunteers
-
SIEMERS E., SKINNER M., DEAN R.A. et al. -Safety, tolerability, and changes in amyloid beta concentration after administration of a gamma-secretase inhibitor in volunteers. Clin. Neuropharmacol., 2005, 28, 126-132
-
(2005)
Clin. Neuropharmacol.
, vol.28
, pp. 126-132
-
-
Siemers, E.1
Skinner, M.2
Dean, R.A.3
-
46
-
-
12444313989
-
Treatment with the selective muscarinic ml agonist talsaclidine decreases cerebrospinal fluid levels of A beta 42 in patients with Alzheimer's disease
-
HOCK C., MADDALENA A., RASCHIG A., MÜLLER-SPAHN F., ESCHWEILER G. et coll. -Treatment with the selective muscarinic ml agonist talsaclidine decreases cerebrospinal fluid levels of A beta 42 in patients with Alzheimer's disease. Amyloid, 2003, 10, 1-6.
-
(2003)
Amyloid
, vol.10
, pp. 1-6
-
-
Hock, C.1
Maddalena, A.2
Raschig, A.3
Müller-Spahn, F.4
Eschweiler, G.5
-
47
-
-
3342934646
-
Therapeutic effects of PKC activators in Alzheimer's disease transgenic mice
-
ETCHEBERRIGARAY R., TAN M., DEWATCHTER I. et al. -Therapeutic effects of PKC activators in Alzheimer's disease transgenic mice. Proc. Natl. Acad. Sci. USA, 2004, 101, 1141-1146
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1141-1146
-
-
Etcheberrigaray, R.1
Tan, M.2
Dewatchter, I.3
-
48
-
-
0033536163
-
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
-
SCHENK D., BARBOUR R., DUNN W. et al. -Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse, Nature, 1999, 400, 173-177.
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
-
49
-
-
0034700471
-
A peptide immunisation reduces behavioural impairment and plaques in a model of Alzheimer's disease
-
JANUS C., PEARSIN J., MCLAURIN J. et al. -A peptide immunisation reduces behavioural impairment and plaques in a model of Alzheimer's disease. Nature, 2000, 408, 979-982
-
(2000)
Nature
, vol.408
, pp. 979-982
-
-
Janus, C.1
Pearsin, J.2
Mclaurin, J.3
-
50
-
-
84984755327
-
Ab peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
-
MORGAN D., DIAMOND D.M., GOTTSCHALL P.E. et al. -Ab peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature, 2000, 408, 982-985
-
(2000)
Nature
, vol.408
, pp. 982-985
-
-
Morgan, D.1
Diamond, D.M.2
Gottschall, P.E.3
-
51
-
-
10744230547
-
Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization
-
ORGOGOZO J.M., GILMAN S., DARTIGUES J.F. et al. -Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization, Neurology, 2003, 61, 46-54.
-
(2003)
Neurology
, vol.61
, pp. 46-54
-
-
Orgogozo, J.M.1
Gilman, S.2
Dartigues, J.F.3
-
52
-
-
20944448555
-
Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial
-
GILMAN S., KOLLER M., BLACK R.S. -Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial. Neurology, 2005, 64, 1553-1562
-
(2005)
Neurology
, vol.64
, pp. 1553-1562
-
-
Gilman, S.1
Koller, M.2
Black, R.S.3
-
53
-
-
18144415471
-
Effects of beta immunization (AN 1792) on MRI measures of cerebral volume in Alzheimer disease
-
Fox N.C, BLACK R.S., GILMAN S. et al. -Effects of beta immunization (AN 1792) on MRI measures of cerebral volume in Alzheimer disease. Neurology, 2005, 64, 1563-1572
-
(2005)
Neurology
, vol.64
, pp. 1563-1572
-
-
Fox, N.C.1
Black, R.S.2
Gilman, S.3
-
54
-
-
0037393454
-
Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: A case report
-
NiCOLL J.A., WILKINSON D., HOLMES C., MARKHAM H., WELLER CO. -Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide : a case report. Nat. Med., 2003, 9, 448-452
-
(2003)
Nat. Med.
, vol.9
, pp. 448-452
-
-
Nicoll, J.A.1
Wilkinson, D.2
Holmes, C.3
Markham, H.4
Weller, C.O.5
-
55
-
-
19944429065
-
Abeta vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer disease
-
MASLIAH E., HANSEN L., ADAM A. et al. -Abeta vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer disease. Neurology, 2005, 64, 129-131
-
(2005)
Neurology
, vol.64
, pp. 129-131
-
-
Masliah, E.1
Hansen, L.2
Adam, A.3
-
56
-
-
0038100154
-
Antobodies against beta-amyloid slow cognitive decline in Alzheimer's disease
-
HOCK C., KONIETZKO U., STREFFER J.R. -Antobodies against beta-amyloid slow cognitive decline in Alzheimer's disease. Neron, 2003, 38, 547-554
-
(2003)
Neron
, vol.38
, pp. 547-554
-
-
Hock, C.1
Konietzko, U.2
Streffer, J.R.3
-
57
-
-
12444268257
-
Prototype Alzheimer's disease vaccine using the immunodominant B cell epitope from beat amyloid and promiscuous T cell epitope pan HLA DR-binding peptide
-
AGADJANYAN M.G., GHOCHIKIAN A., PETRUSHINA I. et al. -Prototype Alzheimer's disease vaccine using the immunodominant B cell epitope from beat amyloid and promiscuous T cell epitope pan HLA DR-binding peptide. J. Immunol., 2005, 174, 1580-1586
-
(2005)
J. Immunol.
, vol.174
, pp. 1580-1586
-
-
Agadjanyan, M.G.1
Ghochikian, A.2
Petrushina, I.3
-
58
-
-
8844256204
-
Intravenous immunoglobulins for Alzheimer's disease
-
FILLIT H. -Intravenous immunoglobulins for Alzheimer's disease. The Lancet Neurology, 2004, 3, 704.
-
(2004)
The Lancet Neurology
, vol.3
, pp. 704
-
-
Fillit, H.1
-
59
-
-
4644275963
-
Intravenous immunoglobulin containing antibodies against beta-amyloid for the treatment of Alzheimer's disease
-
DODEL R.C., Du Y., DEPBOYLU C et al. -Intravenous immunoglobulin containing antibodies against beta-amyloid for the treatment of Alzheimer's disease. J. Neurol. Neurosurg. Psychiatry, 2004, 75, 1472-1514
-
(2004)
J. Neurol. Neurosurg. Psychiatry
, vol.75
, pp. 1472-1514
-
-
Dodel, R.C.1
Du, Y.2
Depboylu, C.3
-
60
-
-
33847662852
-
Soluble protein oligomers in neurodegeneration: Lessons from the Alzheimer's amyloid beta-peptide
-
HAASS C., SELKOE D.J. -Soluble protein oligomers in neurodegeneration : lessons from the Alzheimer's amyloid beta-peptide. Nat. Rev. Mol. Cell Biol., 2007, 8, 101-112
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 101-112
-
-
Haass, C.1
Selkoe, D.J.2
-
61
-
-
0038376613
-
Heparan sulphate proteoglycans in Alzheimer's disease and amyloid-related disorders
-
VAN HORSSEN J., WESSELING P., VAN DEN HEUVEL L.P. et al.- Heparan sulphate proteoglycans in Alzheimer's disease and amyloid-related disorders. Lancet Neurol. 2003, 2, 482-492
-
(2003)
Lancet Neurol.
, vol.2
, pp. 482-492
-
-
Van Horssen, J.1
Wesseling, P.2
Van Den Heuvel, L.P.3
-
62
-
-
10744224267
-
Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: A pilot phase 2 clinical trial
-
RiTCfflE C.W., BUSH A.I., MACKINNON A. ET al. -Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease : a pilot phase 2 clinical trial, Arch. Neurol., 2003, 60, 1685-1691.
-
(2003)
Arch. Neurol.
, vol.60
, pp. 1685-1691
-
-
Ritcffle, C.W.1
Bush, A.I.2
Mackinnon, A.3
-
63
-
-
67651136134
-
Tauopathie et maladie ď Alzhemer, un processus dégénératif à part entière
-
BUÉE L., DELACOURTE A.-Tauopathie et maladie ď Alzhemer, un processus dégénératif à part entière. Psychol. Neuropsychiatr. Vieil., 2006, 4, 1-12.
-
(2006)
Arch. Neurol.
, vol.4
, pp. 1-12
-
-
Buée, L.1
Delacourte, A.2
-
64
-
-
28944431913
-
Animal models of Alzheimer's disease: A road full of pitfalls
-
DELACOURTE A., BUÉE L. -Animal models of Alzheimer's disease : A road full of pitfalls. Psychol. Neuropsychiatr. Vieil., 2005, 3, 261-270.
-
(2005)
Psychol. Neuropsychiatr. Vieil.
, vol.3
, pp. 261-270
-
-
Delacourte, A.1
Buée, L.2
-
65
-
-
0033850407
-
Tau proteins isoforms, phosphorylation and role in neurodegenerative disorders
-
BUÉE L., BUSSIÈRE T., BUÉE-SCHERRER V., DELACOURTE A., HOF P.R. -Tau proteins isoforms, phosphorylation and role in neurodegenerative disorders. Brain Res. Rev., 2000, 33, 95-130.
-
(2000)
Brain Res. Rev.
, vol.33
, pp. 95-130
-
-
Buée, L.1
Bussière, T.2
Buée-Scherrer, V.3
Delacourte, A.4
Hof, P.R.5
-
66
-
-
34548478820
-
Lithium: A novel treatment for Alzheimer's disease?
-
ZHONG J., LEE WH. -Lithium : a novel treatment for Alzheimer's disease ? Expert Opin. Drug Saf., 2007, 6, 375-383
-
(2007)
Expert Opin. Drug Saf.
, vol.6
, pp. 375-383
-
-
Zhong, J.1
Lee, W.H.2
-
67
-
-
33745370049
-
Involvement of I2PP2A in the abnormal hyperphosphorylation of tau and its reversal by Memantine
-
CHOHAN M.O., KHATOON S., IQBAL I.G., IQBAL K. -Involvement of I2PP2A in the abnormal hyperphosphorylation of tau and its reversal by Memantine. FEBS Lett. 2006, 580, 3973-3979
-
(2006)
FEBS Lett.
, vol.580
, pp. 3973-3979
-
-
Chohan, M.O.1
Khatoon, S.2
Iqbal, I.G.3
Iqbal, K.4
-
68
-
-
13544251748
-
Antrhaquinones inhibit tau aggregation and dissolve Alzheimer's paired helical filaments in vitro and in cells
-
PICKHARDT M., GAZOVA Z., VON BERGEN M. et al. -Antrhaquinones inhibit tau aggregation and dissolve Alzheimer's paired helical filaments in vitro and in cells. J. Biol. Chem., 2005,280, 3628-3635
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 3628-3635
-
-
Pickhardt, M.1
Gazova, Z.2
Von Bergen, M.3
-
69
-
-
17044435830
-
Tau phosphorylation in Alzheimer's disease: Pathogen or protector?
-
LEE H.G., PERRY G., MOREIRA P.L. ET al. -Tau phosphorylation in Alzheimer's disease : pathogen or protector ? Trends Mol. Med., 2005, 11, 164-169
-
(2005)
Trends Mol. Med.
, vol.11
, pp. 164-169
-
-
Lee, H.G.1
Perry, G.2
Moreira, P.L.3
-
70
-
-
0028122463
-
Differences in the pattern of hippocampal neuronal loss in normal aging and Alzheimer disease
-
WEST M.J., COLEMAN P.D., FLOOD D.G., TRONCOSO J.C. -Differences in the pattern of hippocampal neuronal loss in normal aging and Alzheimer disease Lancet, 1994, 344, 769-772.
-
(1994)
Lancet
, vol.344
, pp. 769-772
-
-
West, M.J.1
Coleman, P.D.2
Flood, D.G.3
Troncoso, J.C.4
-
71
-
-
21044458854
-
A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease
-
TUSZYNSKI M.H., THAL L., PAY M., SALMON D.P., U.H.S., BAKAY R., PATEL P. et al. -A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease. Nat. Med., 2005,11, 551-555.
-
(2005)
Nat. Med.
, vol.11
, pp. 551-555
-
-
Tuszynski, M.H.1
Thal, L.2
Pay, M.3
Salmon, D.P.U.H.S.4
Bakay, R.5
Patel, P.6
-
72
-
-
34249941829
-
Nerve growth factor gene therapy in Alzheimer disease
-
TUSZYNSKI M.H. -Nerve growth factor gene therapy in Alzheimer disease. Alzheimer Dis. Assoc Disord., 2007, 27, 179-189.
-
(2007)
Alzheimer Dis. Assoc Disord.
, vol.27
, pp. 179-189
-
-
Tuszynski, M.H.1
-
73
-
-
32644432029
-
Clinical relevance of the neurotrophins and their receptors
-
ALLEN S.J., DAWBARN D. -Clinical relevance of the neurotrophins and their receptors. Clin. Sci. (Lond), 2006, 110, 175-191
-
(2006)
Clin. Sci. (Lond)
, vol.110
, pp. 175-191
-
-
Allen, S.J.1
Dawbarn, D.2
-
74
-
-
33747817727
-
Altered neurogenesis in Alzheimer's disease
-
ZIABREVA I., PERRY E., PERRY R., MINGER S.L., EKONOMOU A., PRZYBORSKI S., BALLARD C - Altered neurogenesis in Alzheimer's disease. J. Psychosom. Res., 2006, 61, 311-316
-
(2006)
J. Psychosom. Res.
, vol.61
, pp. 311-316
-
-
Ziabreva, I.1
Perry, E.2
Perry, R.3
Minger, S.L.4
Ekonomou, A.5
Przyborski, S.6
Ballard, C.7
-
75
-
-
33645857366
-
Preclinical analyses of the therapeutic potential of allopregnanolone to promote neurogenesis in vitro and in vivo in transgenic mouse model of Alzheimer's disease
-
BRINTON R.D., WANG J.M. -Preclinical analyses of the therapeutic potential of allopregnanolone to promote neurogenesis in vitro and in vivo in transgenic mouse model of Alzheimer's disease. Curr. Alzheimer Res., 2006, 3, 11-17
-
(2006)
Curr. Alzheimer Res.
, vol.3
, pp. 11-17
-
-
Brinton, R.D.1
Wang, J.M.2
-
76
-
-
34249336353
-
Trophic factors counteract elevated FGF-2-induced inhibition of adult neurogenesis
-
CHEN H., TUNG Y.C, LI B., IQBAL K., GRUNDKE-IQBAL I. -Trophic factors counteract elevated FGF-2-induced inhibition of adult neurogenesis. Neurobiol. Aging. 2007, 28, 1148-1162
-
(2007)
Neurobiol. Aging.
, vol.28
, pp. 1148-1162
-
-
Chen, H.1
Tung, Y.C.2
Li, B.3
Iqbal, K.4
Grundke-Iqbal, I.5
-
77
-
-
34447629569
-
Therapeutic approaches for prion and Alzheimer's diseases
-
WISNIEWSKI T., SIGURDSSON E.M. -Therapeutic approaches for prion and Alzheimer's diseases. FEBS J., 2007, 274, 3784-3798
-
(2007)
FEBS J.
, vol.274
, pp. 3784-3798
-
-
Wisniewski, T.1
Sigurdsson, E.M.2
-
78
-
-
33947151122
-
The cell cycle hypothesis of Alzheimer's disease: Suggestions for drug development
-
WOODS J., SNAPE M., SMITH M.A. -The cell cycle hypothesis of Alzheimer's disease : suggestions for drug development. Biochim. Biophys Acta., 2007, 1772, 503-508
-
(2007)
Biochim. Biophys Acta.
, vol.1772
, pp. 503-508
-
-
Woods, J.1
Snape, M.2
Smith, M.A.3
-
79
-
-
34249040510
-
Blood-brain barrier impairment in Alzheimer disease: Stability and functional significance
-
BOWMAN G.L., KAYE J.A., MOORE M., WAICHUNAS B.A., CARLSON N.E., QUINN JF. - Blood-brain barrier impairment in Alzheimer disease : stability and functional significance. Neurology, 2007, 68, 1809-1814.
-
(2007)
Neurology
, vol.68
, pp. 1809-1814
-
-
Bowman, G.L.1
Kaye, J.A.2
Moore, M.3
Waichunas, B.A.4
Carlson, N.E.5
Quinn, J.F.6
-
80
-
-
34250623663
-
Blood-brain barrier pathology in Alzheimer's and Parkinson's disease: Implications for drug therapy
-
DESAI B.S., MONAHAN AJ., CARVEY P.M., HENDEY B. -Blood-brain barrier pathology in Alzheimer's and Parkinson's disease : implications for drug therapy. Cell Transplant., 2007,16, 285-299
-
(2007)
Cell Transplant.
, vol.16
, pp. 285-299
-
-
Desai, B.S.1
Monahan, A.J.2
Carvey, P.M.3
Hendey, B.4
-
81
-
-
0031971692
-
Fallacies in the pathological confirmation of the diagnosis of Alzheimer's disease
-
BOWLER J.V., MUNOZ D.G., MERSKEY H., HACHTNSKI V. -Fallacies in the pathological confirmation of the diagnosis of Alzheimer's disease. J. Neurol. Neurosurg. Psychiatry, 1988,64, 18-24.
-
(1988)
J. Neurol. Neurosurg. Psychiatry
, vol.64
, pp. 18-24
-
-
Bowler, J.V.1
Munoz, D.G.2
Merskey, H.3
Hachtnski, V.4
-
82
-
-
67651133432
-
Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales
-
Neuropathology Group study of the Medical Research Council Cognitive Function and Aged study (MRC CFAS)
-
Neuropathology Group study of the Medical Research Council Cognitive Function and Aged study (MRC CFAS) Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales. The Lancet, 2001, 357, 168-175.
-
(2001)
The Lancet
, vol.357
, pp. 168-175
-
-
-
83
-
-
0036459947
-
Alzheimer's disease and brain infarcts in the elderly. Agreement with neuropathology
-
ZEKRY D., DUYCKAERTS C., BELMIN J., GEOFFRE C., MOULIAS R., HAUW JJ. -Alzheimer's disease and brain infarcts in the elderly. Agreement with neuropathology. J. Neurol, 2002, 249, 1529-1534.
-
(2002)
J. Neurol
, vol.249
, pp. 1529-1534
-
-
Zekry, D.1
Duyckaerts, C.2
Belmin, J.3
Geoffre, C.4
Moulias, R.5
Hauw, J.J.6
-
84
-
-
0030634117
-
Prevention protocols for Alzheimer disease: Position paper from the International Working Group on Harmonization of Dementia Drug Guidelines
-
THAL L.J., CARTA A., DOODY R., LEBER P., MOHS R., SCHNEIDER L., SHIMOHAMA S., SILBER C - Prevention protocols for Alzheimer disease : position paper from the International Working Group on Harmonization of Dementia Drug Guidelines. Alzheimer Dis. Assoc. Disord, 1997, 11(suppl 3), 46-49.
-
(1997)
Alzheimer Dis. Assoc. Disord
, vol.11
, Issue.SUPPL. 3
, pp. 46-49
-
-
Thal, L.J.1
Carta, A.2
Doody, R.3
Leber, P.4
Mohs, R.5
Schneider, L.6
Shimohama, S.7
Silber, C.8
-
85
-
-
0031695197
-
Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset
-
BROOKMEYER R. et al. -Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset. Am. J. Public Health., 1998, 88, 1337-1342.
-
(1998)
Am. J. Public Health.
, vol.88
, pp. 1337-1342
-
-
Brookmeyer, R.1
-
86
-
-
35848962080
-
Disease-modifying therapies for Alzheimer disease. Challenge to early intervention
-
CUMMINGS J.L., DOODY R., CLARK C. -Disease-modifying therapies for Alzheimer disease. Challenge to early intervention. Neurology, 2007, 69, 1622-1634.
-
(2007)
Neurology
, vol.69
, pp. 1622-1634
-
-
Cummings, J.L.1
Doody, R.2
Clark, C.3
-
87
-
-
34248593249
-
Primary prevention and delay of onset of AD/dementia
-
FELDMAN H.H., JACOVA C. -Primary prevention and delay of onset of AD/dementia. Can. J. Neurol. Sci., 2007, 34 S, 84-89.
-
(2007)
Can. J. Neurol. Sci.
, vol.34
, pp. 84-89
-
-
Feldman, H.H.1
Jacova, C.2
|