Designed folding of pseudopeptides: The transformation of a configurationally driven preorganization into a stereoselective multicomponent macrocyclization reaction

Chemistry - A European Journal

Volumn 14, Issue 29, 2008, Pages 8879-8891

  Alfonso, Ignacio ^a   Bolte, Michael ^b   Bru, Miriam ^c   Isabel Burguete, M ^c   Luis, Santiago V ^c  

^a DEPARTMENT OF ENVIRONMENTAL CHEMISTRY   (Spain)

^b GOETHE UNIVERSITY   (Germany)

^c UAMOA   (Spain)

Author keywords

Conformation analysis; Foldamers; Macrocycles; Peptide like structures; Preorganization

Indexed keywords

AMINES; DICHROISM; NITROGEN COMPOUNDS; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OPTICAL DEVICES; OPTICAL PROPERTIES; WATER ANALYSIS;

AMIDOAMINE; CHIRAL CENTERS; CHLORIDE ANIONS; CIRCULAR DICHROISMS; CONFIGURATIONALLY; CONFORMATION ANALYSIS; CYCLIC DIAMINES; DIAMINE MOIETIES; EFFICIENT SYNTHESES; FOLDAMERS; INTERSTITIAL CHANNELS; MACROCYCLES; MACROCYCLIC; MACROCYCLIC RINGS; MACROCYCLIZATION REACTIONS; MODEL COMPOUNDS; MODELING; NMR SPECTROSCOPIES; PREORGANIZATION; RAY ANALYSES; REDUCTIVE AMINATION; STEREOSELECTIVE; STRUCTURAL INFORMATIONS; STRUCTURAL STUDIES; SYNERGISTIC EFFECTS;

CIRCULAR DICHROISM SPECTROSCOPY;

PEPTIDE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CIRCULAR DICHROISM; CONFORMATION; CRYSTALLIZATION; CYCLIZATION; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN FOLDING; STEREOISOMERISM;

CIRCULAR DICHROISM; CRYSTALLIZATION; CYCLIZATION; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PEPTIDES; PROTEIN FOLDING; STEREOISOMERISM;

EID: 55049142427     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.200800726     Document Type: Article

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