Contribution of a single-turn α-helix to the conformational stability and activity of the alkaline proteinase inhibitor of Pseudomonas aeruginosa

Biochemistry

Volumn 44, Issue 7, 2005, Pages 2469-2477

  Gray, Robert D ^a,b   Trent, John O ^a  

^a University of Louisville School of Medicine   (United States)

^b UNIVERSITY OF LOUISVILLE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BACTERIA; CONFORMATIONS; DIFFERENTIAL SCANNING CALORIMETRY; DISSOCIATION; HYDROGEN BONDS; MUTAGENS; REACTION KINETICS; REDUCTION; SOLVENTS;

BACTERIAL METALLOPROTEINASES; CHEMICAL DENATURATION; PSEUDOMONAS AERUGINOSA (APRIN); SERRALYSIN;

PROTEINS;

ALKALINE PROTEINASE INHIBITOR; BACTERIAL ENZYME; BACTERIAL PROTEIN; ENZYME INHIBITOR; GUANIDINE; METALLOPROTEINASE; SERRALYSIN; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; BINDING AFFINITY; CHEMICAL BOND; CIRCULAR DICHROISM; DIFFERENTIAL SCANNING CALORIMETRY; DISSOCIATION; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME STABILITY; HYDROGEN BOND; MELTING POINT; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN FAMILY; PROTEIN FOLDING; PSEUDOMONAS AERUGINOSA; SOLVATION; TEMPERATURE DEPENDENCE; THERMAL ANALYSIS; WILD TYPE;

AMINO ACID SEQUENCE; CALORIMETRY, DIFFERENTIAL SCANNING; CIRCULAR DICHROISM; COMPUTER SIMULATION; DISULFIDES; GUANIDINE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OXIDATION-REDUCTION; PEPTIDES; PROTEASE INHIBITORS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PSEUDOMONAS AERUGINOSA; THERMODYNAMICS;

EID: 14044278208     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi048287q     Document Type: Article

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