-
2
-
-
0037841763
-
Transcription start regions in the human genome are favored targets for MLV integration
-
X Wu Y Li B Crise SM Burgess 2003 Transcription start regions in the human genome are favored targets for MLV integration Science 300 1749 1751
-
(2003)
Science
, vol.300
, pp. 1749-1751
-
-
Wu, X.1
Li, Y.2
Crise, B.3
Burgess, S.M.4
-
4
-
-
19344375031
-
Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences
-
RS Mitchell BF Beitzel AR Schroder P Shinn H Chen CC Berry JR Ecker FD Bushman 2004 Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences PLoS Biol 2 E234
-
(2004)
PLoS Biol
, vol.2
, pp. 234
-
-
Mitchell, R.S.1
Beitzel, B.F.2
Schroder, A.R.3
Shinn, P.4
Chen, H.5
Berry, C.C.6
Ecker, J.R.7
Bushman, F.D.8
-
5
-
-
10744233606
-
Chance or necessity? Insertional mutagenesis in gene therapy and its consequences
-
C Baum C von Kalle FJ Staal Z Li B Fehse M Schmidt F Weerkamp S Karlsson G Wagemaker DA Williams 2004 Chance or necessity? Insertional mutagenesis in gene therapy and its consequences Mol Ther 9 5 13
-
(2004)
Mol Ther
, vol.9
, pp. 5-13
-
-
Baum, C.1
Von Kalle, C.2
Staal, F.J.3
Li, Z.4
Fehse, B.5
Schmidt, M.6
Weerkamp, F.7
Karlsson, S.8
Wagemaker, G.9
Williams, D.A.10
-
6
-
-
0037129435
-
Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy
-
S Hacein-Bey-Abina F Le Deist F Carlier C Bouneaud C Hue JP De Villartay AJ Thrasher N Wulffraat R Sorensen S Dupuis-Girod 2002 Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy N Engl J Med 346 1185 1193
-
(2002)
N Engl J Med
, vol.346
, pp. 1185-1193
-
-
Hacein-Bey-Abina, S.1
Le Deist, F.2
Carlier, F.3
Bouneaud, C.4
Hue, C.5
De Villartay, J.P.6
Thrasher, A.J.7
Wulffraat, N.8
Sorensen, R.9
Dupuis-Girod, S.10
-
7
-
-
0142084745
-
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
-
S Hacein-Bey-Abina C Von Kalle M Schmidt MP McCormack N Wulffraat P Leboulch A Lim CS Osborne R Pawliuk E Morillon 2003 LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1 Science 302 415 419
-
(2003)
Science
, vol.302
, pp. 415-419
-
-
Hacein-Bey-Abina, S.1
Von Kalle, C.2
Schmidt, M.3
McCormack, M.P.4
Wulffraat, N.5
Leboulch, P.6
Lim, A.7
Osborne, C.S.8
Pawliuk, R.9
Morillon, E.10
-
8
-
-
34547118806
-
What are the consequences of the fourth case?
-
C Baum 2007 What are the consequences of the fourth case? Mol Ther 15 1401 1402
-
(2007)
Mol Ther
, vol.15
, pp. 1401-1402
-
-
Baum, C.1
-
10
-
-
0037189401
-
Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning
-
A Aiuti S Slavin M Aker F Ficara S Deola A Mortellaro S Morecki G Andolfi A Tabucchi F Carlucci 2002 Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning Science 296 2410 2413
-
(2002)
Science
, vol.296
, pp. 2410-2413
-
-
Aiuti, A.1
Slavin, S.2
Aker, M.3
Ficara, F.4
Deola, S.5
Mortellaro, A.6
Morecki, S.7
Andolfi, G.8
Tabucchi, A.9
Carlucci, F.10
-
11
-
-
4644258829
-
Adenoviral vectors for gene transfer and therapy
-
Suppl 1
-
C Volpers S Kochanek 2004 Adenoviral vectors for gene transfer and therapy J Gene Med 6 Suppl 1 S164 S171
-
(2004)
J Gene Med
, vol.6
-
-
Volpers, C.1
Kochanek, S.2
-
12
-
-
0142089747
-
Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer
-
SE Raper N Chirmule FS Lee NA Wivel A Bagg GP Gao JM Wilson ML Batshaw 2003 Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer Mol Genet Metab 80 148 158
-
(2003)
Mol Genet Metab
, vol.80
, pp. 148-158
-
-
Raper, S.E.1
Chirmule, N.2
Lee, F.S.3
Wivel, N.A.4
Bagg, A.5
Gao, G.P.6
Wilson, J.M.7
Batshaw, M.L.8
-
13
-
-
0030756821
-
Gene therapy with recombinant adenovirus vectors: Evaluation of the host immune response
-
M Christ M Lusky F Stoeckel D Dreyer A Dieterle AI Michou A Pavirani M Mehtali 1997 Gene therapy with recombinant adenovirus vectors: evaluation of the host immune response Immunol Lett 57 19 25
-
(1997)
Immunol Lett
, vol.57
, pp. 19-25
-
-
Christ, M.1
Lusky, M.2
Stoeckel, F.3
Dreyer, D.4
Dieterle, A.5
Michou, A.I.6
Pavirani, A.7
Mehtali, M.8
-
14
-
-
0028934815
-
Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: Tolerization of factor IX and vector antigens allows for long-term expression
-
Y Dai EM Schwarz D Gu WW Zhang N Sarvetnick IM Verma 1995 Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression Proc Natl Acad Sci USA 92 1401 1405
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 1401-1405
-
-
Dai, Y.1
Schwarz, E.M.2
Gu, D.3
Zhang, W.W.4
Sarvetnick, N.5
Verma, I.M.6
-
15
-
-
2442638935
-
Helper-dependent adenovirus vectors elicit intact innate but attenuated adaptive host immune responses in vivo
-
DA Muruve MJ Cotter AK Zaiss LR White Q Liu T Chan SA Clark PJ Ross RA Meulenbroek GM Maelandsmo 2004 Helper-dependent adenovirus vectors elicit intact innate but attenuated adaptive host immune responses in vivo J Virol 78 5966 5972
-
(2004)
J Virol
, vol.78
, pp. 5966-5972
-
-
Muruve, D.A.1
Cotter, M.J.2
Zaiss, A.K.3
White, L.R.4
Liu, Q.5
Chan, T.6
Clark, S.A.7
Ross, P.J.8
Meulenbroek, R.A.9
Maelandsmo, G.M.10
-
16
-
-
0037790861
-
Episomal persistence of recombinant adenoviral vector genomes during the cell cycle in vivo
-
A Ehrhardt H Xu MA Kay 2003 Episomal persistence of recombinant adenoviral vector genomes during the cell cycle in vivo J Virol 77 7689 7695
-
(2003)
J Virol
, vol.77
, pp. 7689-7695
-
-
Ehrhardt, A.1
Xu, H.2
Kay, M.A.3
-
17
-
-
10944269753
-
Integration of adeno-associated virus (AAV) and recombinant AAV vectors
-
DM McCarty SM Young Jr RJ Samulski 2004 Integration of adeno-associated virus (AAV) and recombinant AAV vectors Annu Rev Genet 38 819 845
-
(2004)
Annu Rev Genet
, vol.38
, pp. 819-845
-
-
McCarty, D.M.1
Young Jr., S.M.2
Samulski, R.J.3
-
19
-
-
0035401236
-
Nonviral gene therapy
-
S Li Z Ma 2001 Nonviral gene therapy Curr Gene Ther 1 201 126
-
(2001)
Curr Gene Ther
, vol.1
, pp. 201-126
-
-
Li, S.1
Ma, Z.2
-
21
-
-
0031897270
-
Human gene targeting by viral vectors
-
DW Russell RK Hirata 1998 Human gene targeting by viral vectors Nat Genet 18 325 330
-
(1998)
Nat Genet
, vol.18
, pp. 325-330
-
-
Russell, D.W.1
Hirata, R.K.2
-
22
-
-
0034252499
-
The DNA segregation mechanism of Epstein-Barr virus nuclear antigen 1
-
H Wu DF Ceccarelli L Frappier 2000 The DNA segregation mechanism of Epstein-Barr virus nuclear antigen 1 EMBO Rep 1 140 144
-
(2000)
EMBO Rep
, vol.1
, pp. 140-144
-
-
Wu, H.1
Ceccarelli, D.F.2
Frappier, L.3
-
23
-
-
0033555686
-
A vector based on the SV40 origin of replication and chromosomal S/MARs replicates episomally in CHO cells
-
C Piechaczek C Fetzer A Baiker J Bode HJ Lipps 1999 A vector based on the SV40 origin of replication and chromosomal S/MARs replicates episomally in CHO cells Nucleic Acids Res 27 426 428
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 426-428
-
-
Piechaczek, C.1
Fetzer, C.2
Baiker, A.3
Bode, J.4
Lipps, H.J.5
-
24
-
-
34648834046
-
Epstein-Barr virus latent nuclear antigens can induce metastasis in a nude mouse model
-
R Kaul M Murakami T Choudhuri ES Robertson 2007 Epstein-Barr virus latent nuclear antigens can induce metastasis in a nude mouse model J Virol 81 10352 10361
-
(2007)
J Virol
, vol.81
, pp. 10352-10361
-
-
Kaul, R.1
Murakami, M.2
Choudhuri, T.3
Robertson, E.S.4
-
25
-
-
3042712903
-
Epstein-Barr virus sustains Burkitt's lymphomas and Hodgkin's disease
-
W Hammerschmidt B Sugden 2004 Epstein-Barr virus sustains Burkitt's lymphomas and Hodgkin's disease Trends Mol Med 10 331 336
-
(2004)
Trends Mol Med
, vol.10
, pp. 331-336
-
-
Hammerschmidt, W.1
Sugden, B.2
-
26
-
-
0035027365
-
Satellite DNA-based artificial chromosomes for use in gene therapy
-
G Hadlaczky 2001 Satellite DNA-based artificial chromosomes for use in gene therapy Curr Opin Mol Ther 3 125 132
-
(2001)
Curr Opin Mol Ther
, vol.3
, pp. 125-132
-
-
Hadlaczky, G.1
-
27
-
-
0030662074
-
Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells
-
Z Ivics PB Hackett RH Plasterk Z Izsvak 1997 Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells Cell 91 501 510
-
(1997)
Cell
, vol.91
, pp. 501-510
-
-
Ivics, Z.1
Hackett, P.B.2
Plasterk, R.H.3
Izsvak, Z.4
-
28
-
-
0344668818
-
The Frog Prince: A reconstructed transposon from Rana pipiens with high transpositional activity in vertebrate cells
-
C Miskey Z Izsvak RH Plasterk Z Ivics 2003 The Frog Prince: a reconstructed transposon from Rana pipiens with high transpositional activity in vertebrate cells Nucleic Acids Res 31 6873 6881
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 6873-6881
-
-
Miskey, C.1
Izsvak, Z.2
Plasterk, R.H.3
Ivics, Z.4
-
29
-
-
33749536744
-
Transposons for gene therapy!
-
Z Ivics Z Izsvak 2006 Transposons for gene therapy! Curr Gene Ther 6 593 607
-
(2006)
Curr Gene Ther
, vol.6
, pp. 593-607
-
-
Ivics, Z.1
Izsvak, Z.2
-
31
-
-
32944457236
-
Neuronal precursor-restricted transduction via in utero CNS gene delivery of a novel bipartite HSV amplicon/transposase hybrid vector
-
WJ Bowers MA Mastrangelo DF Howard HA Southerland KA Maguire-Zeiss HJ Federoff 2006 Neuronal precursor-restricted transduction via in utero CNS gene delivery of a novel bipartite HSV amplicon/transposase hybrid vector Mol Ther 13 580 588
-
(2006)
Mol Ther
, vol.13
, pp. 580-588
-
-
Bowers, W.J.1
Mastrangelo, M.A.2
Howard, D.F.3
Southerland, H.A.4
Maguire-Zeiss, K.A.5
Federoff, H.J.6
-
32
-
-
38449121886
-
Technology transfer from worms and flies to vertebrates: Transposition-based genome manipulations and their future perspectives
-
Suppl 1
-
L Mates Z Izsvak Z Ivics 2007 Technology transfer from worms and flies to vertebrates: transposition-based genome manipulations and their future perspectives Genome Biol 8 Suppl 1 S1
-
(2007)
Genome Biol
, vol.8
, pp. 1
-
-
Mates, L.1
Izsvak, Z.2
Ivics, Z.3
-
33
-
-
0036404918
-
Common physical properties of DNA affecting target site selection of Sleeping Beauty and other Tc1/mariner transposable elements
-
TJ Vigdal CD Kaufman Z Izsvák DF Voytas Z Ivics 2002 Common physical properties of DNA affecting target site selection of Sleeping Beauty and other Tc1/mariner transposable elements J Mol Biol 323 441 452
-
(2002)
J Mol Biol
, vol.323
, pp. 441-452
-
-
Vigdal, T.J.1
Kaufman, C.D.2
Izsvák, Z.3
Voytas, D.F.4
Ivics, Z.5
-
34
-
-
19944431736
-
Target-site preferences of Sleeping Beauty transposons
-
G Liu AM Geurts K Yae AR Srinivasan SC Fahrenkrug DA Largaespada J Takeda K Horie WK Olson PB Hackett 2005 Target-site preferences of Sleeping Beauty transposons J Mol Biol 346 161 173
-
(2005)
J Mol Biol
, vol.346
, pp. 161-173
-
-
Liu, G.1
Geurts, A.M.2
Yae, K.3
Srinivasan, A.R.4
Fahrenkrug, S.C.5
Largaespada, D.A.6
Takeda, J.7
Horie, K.8
Olson, W.K.9
Hackett, P.B.10
-
36
-
-
38649084453
-
Transcriptional activities of the Sleeping Beauty transposon and shielding its genetic cargo with insulators
-
O Walisko A Schorn F Rolfs A Devaraj C Miskey Z Izsvak Z Ivics 2008 Transcriptional activities of the Sleeping Beauty transposon and shielding its genetic cargo with insulators Mol Ther 16 359 369
-
(2008)
Mol Ther
, vol.16
, pp. 359-369
-
-
Walisko, O.1
Schorn, A.2
Rolfs, F.3
Devaraj, A.4
Miskey, C.5
Izsvak, Z.6
Ivics, Z.7
-
37
-
-
33746389397
-
Sleeping beauty: A novel cancer gene discovery tool
-
Spec No 1
-
AJ Dupuy NA Jenkins NG Copeland 2006 Sleeping beauty: a novel cancer gene discovery tool Hum Mol Genet 15 Spec No 1 R75 R79
-
(2006)
Hum Mol Genet
, vol.15
-
-
Dupuy, A.J.1
Jenkins, N.A.2
Copeland, N.G.3
-
38
-
-
28044461707
-
Somatic integration of an oncogene-harboring Sleeping Beauty transposon models liver tumor development in the mouse
-
CM Carlson JL Frandsen N Kirchhof RS McIvor DA Largaespada 2005 Somatic integration of an oncogene-harboring Sleeping Beauty transposon models liver tumor development in the mouse Proc Natl Acad Sci USA 102 17059 17064
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 17059-17064
-
-
Carlson, C.M.1
Frandsen, J.L.2
Kirchhof, N.3
McIvor, R.S.4
Largaespada, D.A.5
-
39
-
-
33845981514
-
PiggyBac transposon-mediated gene transfer in human cells
-
MH Wilson CJ Coates AL George Jr 2007 PiggyBac transposon-mediated gene transfer in human cells Mol Ther 15 139 145
-
(2007)
Mol Ther
, vol.15
, pp. 139-145
-
-
Wilson, M.H.1
Coates, C.J.2
George Jr., A.L.3
-
40
-
-
23744479962
-
Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice
-
S Ding X Wu G Li M Han Y Zhuang T Xu 2005 Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice Cell 122 473 483
-
(2005)
Cell
, vol.122
, pp. 473-483
-
-
Ding, S.1
Wu, X.2
Li, G.3
Han, M.4
Zhuang, Y.5
Xu, T.6
-
42
-
-
38449110499
-
Tol2: A versatile gene transfer vector in vertebrates
-
Suppl 1
-
K Kawakami 2007 Tol2: a versatile gene transfer vector in vertebrates Genome Biol 8 Suppl 1 S7
-
(2007)
Genome Biol
, vol.8
, pp. 7
-
-
Kawakami, K.1
-
43
-
-
33751352744
-
Harnessing a high cargo-capacity transposon for genetic applications in vertebrates
-
D Balciunas KJ Wangensteen A Wilber J Bell A Geurts S Sivasubbu X Wang PB Hackett DA Largaespada RS McIvor 2006 Harnessing a high cargo-capacity transposon for genetic applications in vertebrates PLoS Genet 2 e169
-
(2006)
PLoS Genet
, vol.2
, pp. 169
-
-
Balciunas, D.1
Wangensteen, K.J.2
Wilber, A.3
Bell, J.4
Geurts, A.5
Sivasubbu, S.6
Wang, X.7
Hackett, P.B.8
Largaespada, D.A.9
McIvor, R.S.10
-
44
-
-
33745684269
-
Retroviral DNA integration: Viral and cellular determinants of target-site selection
-
MK Lewinski M Yamashita M Emerman A Ciuffi H Marshall G Crawford F Collins P Shinn J Leipzig S Hannenhalli 2006 Retroviral DNA integration: viral and cellular determinants of target-site selection PLoS Pathog 2 e60
-
(2006)
PLoS Pathog
, vol.2
, pp. 60
-
-
Lewinski, M.K.1
Yamashita, M.2
Emerman, M.3
Ciuffi, A.4
Marshall, H.5
Crawford, G.6
Collins, F.7
Shinn, P.8
Leipzig, J.9
Hannenhalli, S.10
-
45
-
-
28644443483
-
A role for LEDGF/p75 in targeting HIV DNA integration
-
A Ciuffi M Llano E Poeschla C Hoffmann J Leipzig P Shinn JR Ecker F Bushman 2005 A role for LEDGF/p75 in targeting HIV DNA integration Nat Med 11 1287 1289
-
(2005)
Nat Med
, vol.11
, pp. 1287-1289
-
-
Ciuffi, A.1
Llano, M.2
Poeschla, E.3
Hoffmann, C.4
Leipzig, J.5
Shinn, P.6
Ecker, J.R.7
Bushman, F.8
-
46
-
-
0032538795
-
Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation
-
H Ge Y Si RG Roeder 1998 Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation EMBO J 17 6723 6729
-
(1998)
EMBO J
, vol.17
, pp. 6723-6729
-
-
Ge, H.1
Si, Y.2
Roeder, R.G.3
-
47
-
-
4143092604
-
LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes
-
M Llano M Vanegas O Fregoso D Saenz S Chung M Peretz EM Poeschla 2004 LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes J Virol 78 9524 9537
-
(2004)
J Virol
, vol.78
, pp. 9524-9537
-
-
Llano, M.1
Vanegas, M.2
Fregoso, O.3
Saenz, D.4
Chung, S.5
Peretz, M.6
Poeschla, E.M.7
-
48
-
-
24644489049
-
Integration targeting by avian sarcoma-leukosis virus and human immunodeficiency virus in the chicken genome
-
SD Barr J Leipzig P Shinn JR Ecker FD Bushman 2005 Integration targeting by avian sarcoma-leukosis virus and human immunodeficiency virus in the chicken genome J Virol 79 12035 12044
-
(2005)
J Virol
, vol.79
, pp. 12035-12044
-
-
Barr, S.D.1
Leipzig, J.2
Shinn, P.3
Ecker, J.R.4
Bushman, F.D.5
-
49
-
-
0029836836
-
The recombination signals for adeno-associated virus site-specific integration
-
RM Linden E Winocour KI Berns 1996 The recombination signals for adeno-associated virus site-specific integration Proc Natl Acad Sci USA 93 7966 7972
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 7966-7972
-
-
Linden, R.M.1
Winocour, E.2
Berns, K.I.3
-
50
-
-
0028307303
-
Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA
-
MD Weitzman SR Kyostio RM Kotin RA Owens 1994 Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA Proc Natl Acad Sci USA 91 5808 5812
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 5808-5812
-
-
Weitzman, M.D.1
Kyostio, S.R.2
Kotin, R.M.3
Owens, R.A.4
-
51
-
-
0028916052
-
Asymmetric replication in vitro from a human sequence element is dependent on adeno-associated virus Rep protein
-
E Urcelay P Ward SM Wiener B Safer RM Kotin 1995 Asymmetric replication in vitro from a human sequence element is dependent on adeno-associated virus Rep protein J Virol 69 2038 2046
-
(1995)
J Virol
, vol.69
, pp. 2038-2046
-
-
Urcelay, E.1
Ward, P.2
Wiener, S.M.3
Safer, B.4
Kotin, R.M.5
-
53
-
-
4644285407
-
Site-specific integration of functional transgenes into the human genome by adeno/AAV hybrid vectors
-
A Recchia L Perani D Sartori C Olgiati F Mavilio 2004 Site-specific integration of functional transgenes into the human genome by adeno/AAV hybrid vectors Mol Ther 10 660 670
-
(2004)
Mol Ther
, vol.10
, pp. 660-670
-
-
Recchia, A.1
Perani, L.2
Sartori, D.3
Olgiati, C.4
Mavilio, F.5
-
54
-
-
0035923601
-
Adeno-associated virus (AAV) site-specific recombination does not require a Rep-dependent origin of replication within the AAV terminal repeat
-
SM Young Jr RJ Samulski 2001 Adeno-associated virus (AAV) site-specific recombination does not require a Rep-dependent origin of replication within the AAV terminal repeat Proc Natl Acad Sci USA 98 13525 13530
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 13525-13530
-
-
Young Jr., S.M.1
Samulski, R.J.2
-
55
-
-
0035490099
-
Engineering chromosomal rearrangements in mice
-
Y Yu A Bradley 2001 Engineering chromosomal rearrangements in mice Nat Rev Genet 2 780 790
-
(2001)
Nat Rev Genet
, vol.2
, pp. 780-790
-
-
Yu, Y.1
Bradley, A.2
-
56
-
-
0025360095
-
Targeted insertion of exogenous DNA into the eukaryotic genome by the Cre recombinase
-
B Sauer N Henderson 1990 Targeted insertion of exogenous DNA into the eukaryotic genome by the Cre recombinase New Biol 2 441 449
-
(1990)
New Biol
, vol.2
, pp. 441-449
-
-
Sauer, B.1
Henderson, N.2
-
58
-
-
34347398120
-
HIV-1 proviral DNA excision using an evolved recombinase
-
I Sarkar I Hauber J Hauber F Buchholz 2007 HIV-1 proviral DNA excision using an evolved recombinase Science 316 1912 1915
-
(2007)
Science
, vol.316
, pp. 1912-1915
-
-
Sarkar, I.1
Hauber, I.2
Hauber, J.3
Buchholz, F.4
-
59
-
-
0031874849
-
Improved properties of FLP recombinase evolved by cycling mutagenesis
-
F Buchholz PO Angrand AF Stewart 1998 Improved properties of FLP recombinase evolved by cycling mutagenesis Nat Biotechnol 16 657 662
-
(1998)
Nat Biotechnol
, vol.16
, pp. 657-662
-
-
Buchholz, F.1
Angrand, P.O.2
Stewart, A.F.3
-
60
-
-
0035979247
-
Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells
-
A Loonstra M Vooijs HB Beverloo BA Allak E van Drunen R Kanaar A Berns J Jonkers 2001 Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells Proc Natl Acad Sci USA 98 9209 9214
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9209-9214
-
-
Loonstra, A.1
Vooijs, M.2
Beverloo, H.B.3
Allak, B.A.4
Van Drunen, E.5
Kanaar, R.6
Berns, A.7
Jonkers, J.8
-
61
-
-
0032510752
-
In vitro site-specific integration of bacteriophage DNA catalyzed by a recombinase of the resolvase/invertase family
-
HM Thorpe MC Smith 1998 In vitro site-specific integration of bacteriophage DNA catalyzed by a recombinase of the resolvase/invertase family Proc Natl Acad Sci USA 95 5505 5510
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 5505-5510
-
-
Thorpe, H.M.1
Smith, M.C.2
-
62
-
-
33644767178
-
Integration specificity of phage phiC31 integrase in the human genome
-
TW Chalberg JL Portlock EC Olivares B Thyagarajan PJ Kirby RT Hillman J Hoelters MP Calos 2006 Integration specificity of phage phiC31 integrase in the human genome J Mol Biol 357 28 48
-
(2006)
J Mol Biol
, vol.357
, pp. 28-48
-
-
Chalberg, T.W.1
Portlock, J.L.2
Olivares, E.C.3
Thyagarajan, B.4
Kirby, P.J.5
Hillman, R.T.6
Hoelters, J.7
Calos, M.P.8
-
64
-
-
25144432005
-
Site-specific integration with phiC31 integrase for prolonged expression of therapeutic genes
-
DS Ginsburg MP Calos 2005 Site-specific integration with phiC31 integrase for prolonged expression of therapeutic genes Adv Genet 54 179 187
-
(2005)
Adv Genet
, vol.54
, pp. 179-187
-
-
Ginsburg, D.S.1
Calos, M.P.2
-
65
-
-
15944400651
-
Towards safe, non-viral therapeutic gene expression in humans
-
DJ Glover HJ Lipps DA Jans 2005 Towards safe, non-viral therapeutic gene expression in humans Nat Rev Genet 6 299 310
-
(2005)
Nat Rev Genet
, vol.6
, pp. 299-310
-
-
Glover, D.J.1
Lipps, H.J.2
Jans, D.A.3
-
66
-
-
33746124221
-
Phi c31 integrase induces chromosomal aberrations in primary human fibroblasts
-
J Liu I Jeppesen K Nielsen TG Jensen 2006 Phi c31 integrase induces chromosomal aberrations in primary human fibroblasts Gene Ther 13 1188 1190
-
(2006)
Gene Ther
, vol.13
, pp. 1188-1190
-
-
Liu, J.1
Jeppesen, I.2
Nielsen, K.3
Jensen, T.G.4
-
67
-
-
33750997895
-
Molecular analysis of chromosomal rearrangements in mammalian cells after phiC31-mediated integration
-
A Ehrhardt JA Engler H Xu AM Cherry MA Kay 2006 Molecular analysis of chromosomal rearrangements in mammalian cells after phiC31-mediated integration Hum Gene Ther 17 1077 1094
-
(2006)
Hum Gene Ther
, vol.17
, pp. 1077-1094
-
-
Ehrhardt, A.1
Engler, J.A.2
Xu, H.3
Cherry, A.M.4
Kay, M.A.5
-
68
-
-
0031832807
-
Transposable elements and genome organization: A comprehensive survey of retrotransposons revealed by the complete Saccharomyces cerevisiae genome sequence
-
JM Kim S Vanguri JD Boeke A Gabriel DF Voytas 1998 Transposable elements and genome organization: a comprehensive survey of retrotransposons revealed by the complete Saccharomyces cerevisiae genome sequence Genome Res 8 464 478
-
(1998)
Genome Res
, vol.8
, pp. 464-478
-
-
Kim, J.M.1
Vanguri, S.2
Boeke, J.D.3
Gabriel, A.4
Voytas, D.F.5
-
70
-
-
17444372794
-
TFIIIB subunit Bdp1p is required for periodic integration of the Ty1 retrotransposon and targeting of Isw2p to S. cerevisiae tDNAs
-
N Bachman ME Gelbart T Tsukiyama JD Boeke 2005 TFIIIB subunit Bdp1p is required for periodic integration of the Ty1 retrotransposon and targeting of Isw2p to S. cerevisiae tDNAs Genes Dev 19 955 964
-
(2005)
Genes Dev
, vol.19
, pp. 955-964
-
-
Bachman, N.1
Gelbart, M.E.2
Tsukiyama, T.3
Boeke, J.D.4
-
71
-
-
0028936732
-
Requirement of RNA polymerase III transcription factors for in vitro position-specific integration of a retroviruslike element
-
J Kirchner CM Connolly SB Sandmeyer 1995 Requirement of RNA polymerase III transcription factors for in vitro position-specific integration of a retroviruslike element Science 267 1488 1491
-
(1995)
Science
, vol.267
, pp. 1488-1491
-
-
Kirchner, J.1
Connolly, C.M.2
Sandmeyer, S.B.3
-
72
-
-
0037135522
-
Mutational analysis of the transcription factor IIIB-DNA target of Ty3 retroelement integration
-
L Yieh H Hatzis G Kassavetis SB Sandmeyer 2002 Mutational analysis of the transcription factor IIIB-DNA target of Ty3 retroelement integration J Biol Chem 277 25920 25928
-
(2002)
J Biol Chem
, vol.277
, pp. 25920-25928
-
-
Yieh, L.1
Hatzis, H.2
Kassavetis, G.3
Sandmeyer, S.B.4
-
73
-
-
0034775753
-
A truncation mutant of the 95-kilodalton subunit of transcription factor IIIC reveals asymmetry in Ty3 integration
-
M Aye SL Dildine JA Claypool S Jourdain SB Sandmeyer 2001 A truncation mutant of the 95-kilodalton subunit of transcription factor IIIC reveals asymmetry in Ty3 integration Mol Cell Biol 21 7839 7851
-
(2001)
Mol Cell Biol
, vol.21
, pp. 7839-7851
-
-
Aye, M.1
Dildine, S.L.2
Claypool, J.A.3
Jourdain, S.4
Sandmeyer, S.B.5
-
74
-
-
0034816496
-
Targeting of the yeast Ty5 retrotransposon to silent chromatin is mediated by interactions between integrase and Sir4p
-
W Xie X Gai Y Zhu DC Zappulla R Sternglanz DF Voytas 2001 Targeting of the yeast Ty5 retrotransposon to silent chromatin is mediated by interactions between integrase and Sir4p Mol Cell Biol 21 6606 6614
-
(2001)
Mol Cell Biol
, vol.21
, pp. 6606-6614
-
-
Xie, W.1
Gai, X.2
Zhu, Y.3
Zappulla, D.C.4
Sternglanz, R.5
Voytas, D.F.6
-
75
-
-
0029985540
-
The Saccharomyces retrotransposon Ty5 integrates preferentially into regions of silent chromatin at the telomeres and mating loci
-
S Zou N Ke JM Kim DF Voytas 1996 The Saccharomyces retrotransposon Ty5 integrates preferentially into regions of silent chromatin at the telomeres and mating loci Genes Dev 10 634 645
-
(1996)
Genes Dev
, vol.10
, pp. 634-645
-
-
Zou, S.1
Ke, N.2
Kim, J.M.3
Voytas, D.F.4
-
79
-
-
0036970123
-
Dictyostelium mobile elements: Strategies to amplify in a compact genome
-
T Winckler T Dingermann G Glockner 2002 Dictyostelium mobile elements: strategies to amplify in a compact genome Cell Mol Life Sci 59 2097 2111
-
(2002)
Cell Mol Life Sci
, vol.59
, pp. 2097-2111
-
-
Winckler, T.1
Dingermann, T.2
Glockner, G.3
-
80
-
-
23844530544
-
Transfer RNA gene-targeted integration: An adaptation of retrotransposable elements to survive in the compact Dictyostelium discoideum genome
-
T Winckler K Szafranski G Glockner 2005 Transfer RNA gene-targeted integration: an adaptation of retrotransposable elements to survive in the compact Dictyostelium discoideum genome Cytogenet Genome Res 110 288 298
-
(2005)
Cytogenet Genome Res
, vol.110
, pp. 288-298
-
-
Winckler, T.1
Szafranski, K.2
Glockner, G.3
-
81
-
-
37549005579
-
Protein interactions involved in tRNA gene-specific integration of Dictyostelium non-long terminal repeat retrotransposon TRE5-A
-
T Chung O Siol T Dingermann T Winckler 2007 Protein interactions involved in tRNA gene-specific integration of Dictyostelium non-long terminal repeat retrotransposon TRE5-A Mol Cell Biol 27 8492 8501
-
(2007)
Mol Cell Biol
, vol.27
, pp. 8492-8501
-
-
Chung, T.1
Siol, O.2
Dingermann, T.3
Winckler, T.4
-
82
-
-
4143149761
-
Engineering proteins that bind, move, make and break DNA
-
CH Collins Y Yokobayashi D Umeno FH Arnold 2003 Engineering proteins that bind, move, make and break DNA Curr Opin Biotechnol 14 665
-
(2003)
Curr Opin Biotechnol
, vol.14
, pp. 665
-
-
Collins, C.H.1
Yokobayashi, Y.2
Umeno, D.3
Arnold, F.H.4
-
83
-
-
0029862622
-
Targeting of retroviral integrase by fusion to a heterologous DNA binding domain: In vitro activities and incorporation of a fusion protein into viral particles
-
RA Katz G Merkel AM Skalka 1996 Targeting of retroviral integrase by fusion to a heterologous DNA binding domain: in vitro activities and incorporation of a fusion protein into viral particles Virology 217 178 190
-
(1996)
Virology
, vol.217
, pp. 178-190
-
-
Katz, R.A.1
Merkel, G.2
Skalka, A.M.3
-
84
-
-
0028074881
-
Tethering human immunodeficiency virus 1 integrase to a DNA site directs integration to nearby sequences
-
FD Bushman 1994 Tethering human immunodeficiency virus 1 integrase to a DNA site directs integration to nearby sequences Proc Natl Acad Sci USA 91 9233 9237
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9233-9237
-
-
Bushman, F.D.1
-
85
-
-
0029655849
-
Directed integration of viral DNA mediated by fusion proteins consisting of human immunodeficiency virus type 1 integrase and Escherichia coli LexA protein
-
H Goulaouic SA Chow 1996 Directed integration of viral DNA mediated by fusion proteins consisting of human immunodeficiency virus type 1 integrase and Escherichia coli LexA protein J Virol 70 37 46
-
(1996)
J Virol
, vol.70
, pp. 37-46
-
-
Goulaouic, H.1
Chow, S.A.2
-
87
-
-
33845577011
-
Chimeric Mos1 and piggyBac transposases result in site-directed integration
-
KJ Maragathavally JM Kaminski CJ Coates 2006 Chimeric Mos1 and piggyBac transposases result in site-directed integration FASEB J 20 1880 1882
-
(2006)
FASEB J
, vol.20
, pp. 1880-1882
-
-
Maragathavally, K.J.1
Kaminski, J.M.2
Coates, C.J.3
-
88
-
-
33750060436
-
PiggyBac is a flexible and highly active transposon as compared to sleeping beauty, Tol2, and Mos1 in mammalian cells
-
SC Wu YJ Meir CJ Coates AM Handler P Pelczar S Moisyadi JM Kaminski 2006 piggyBac is a flexible and highly active transposon as compared to sleeping beauty, Tol2, and Mos1 in mammalian cells Proc Natl Acad Sci USA 103 15008 15013
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 15008-15013
-
-
Wu, S.C.1
Meir, Y.J.2
Coates, C.J.3
Handler, A.M.4
Pelczar, P.5
Moisyadi, S.6
Kaminski, J.M.7
-
91
-
-
0031060377
-
Tethering human immunodeficiency virus type 1 preintegration complexes to target DNA promotes integration at nearby sites
-
FD Bushman MD Miller 1997 Tethering human immunodeficiency virus type 1 preintegration complexes to target DNA promotes integration at nearby sites J Virol 71 458 464
-
(1997)
J Virol
, vol.71
, pp. 458-464
-
-
Bushman, F.D.1
Miller, M.D.2
-
92
-
-
33747816812
-
Zinc Finger Tools: Custom DNA-binding domains for transcription factors and nucleases
-
JG Mandell CF Barbas 3rd 2006 Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases Nucleic Acids Res 34 W516 W523
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Mandell, J.G.1
Barbas III, C.F.2
-
94
-
-
35948946526
-
Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery
-
A Lombardo P Genovese CM Beausejour S Colleoni YL Lee KA Kim D Ando FD Urnov C Galli PD Gregory 2007 Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery Nat Biotechnol 25 1298 1306
-
(2007)
Nat Biotechnol
, vol.25
, pp. 1298-1306
-
-
Lombardo, A.1
Genovese, P.2
Beausejour, C.M.3
Colleoni, S.4
Lee, Y.L.5
Kim, K.A.6
Ando, D.7
Urnov, F.D.8
Galli, C.9
Gregory, P.D.10
-
95
-
-
0032437591
-
Toward controlling gene expression at will: Specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks
-
RR Beerli DJ Segal B Dreier CF Barbas 3rd 1998 Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks Proc Natl Acad Sci USA 95 14628 14633
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 14628-14633
-
-
Beerli, R.R.1
Segal, D.J.2
Dreier, B.3
Barbas III, C.F.4
-
96
-
-
0347634423
-
Fusion proteins consisting of human immunodeficiency virus type 1 integrase and the designed polydactyl zinc finger protein E2C direct integration of viral DNA into specific sites
-
W Tan K Zhu DJ Segal CF Barbas 3rd SA Chow 2004 Fusion proteins consisting of human immunodeficiency virus type 1 integrase and the designed polydactyl zinc finger protein E2C direct integration of viral DNA into specific sites J Virol 78 1301 1313
-
(2004)
J Virol
, vol.78
, pp. 1301-1313
-
-
Tan, W.1
Zhu, K.2
Segal, D.J.3
Barbas III, C.F.4
Chow, S.A.5
-
97
-
-
32444434997
-
Human immunodeficiency virus type 1 incorporated with fusion proteins consisting of integrase and the designed polydactyl zinc finger protein E2C can bias integration of viral DNA into a predetermined chromosomal region in human cells
-
W Tan Z Dong TA Wilkinson CF Barbas 3rd SA Chow 2006 Human immunodeficiency virus type 1 incorporated with fusion proteins consisting of integrase and the designed polydactyl zinc finger protein E2C can bias integration of viral DNA into a predetermined chromosomal region in human cells J Virol 80 1939 1948
-
(2006)
J Virol
, vol.80
, pp. 1939-1948
-
-
Tan, W.1
Dong, Z.2
Wilkinson, T.A.3
Barbas III, C.F.4
Chow, S.A.5
-
98
-
-
27544441215
-
Functional zinc finger/sleeping beauty transposase chimeras exhibit attenuated overproduction inhibition
-
MH Wilson JM Kaminski AL George Jr 2005 Functional zinc finger/sleeping beauty transposase chimeras exhibit attenuated overproduction inhibition FEBS Lett 579 6205 6209
-
(2005)
FEBS Lett
, vol.579
, pp. 6205-6209
-
-
Wilson, M.H.1
Kaminski, J.M.2
George Jr., A.L.3
-
99
-
-
0034089616
-
The artificial zinc finger coding gene 'Jazz' binds the utrophin promoter and activates transcription
-
N Corbi V Libri M Fanciulli JM Tinsley KE Davies C Passananti 2000 The artificial zinc finger coding gene 'Jazz' binds the utrophin promoter and activates transcription Gene Ther 7 1076 1083
-
(2000)
Gene Ther
, vol.7
, pp. 1076-1083
-
-
Corbi, N.1
Libri, V.2
Fanciulli, M.3
Tinsley, J.M.4
Davies, K.E.5
Passananti, C.6
-
101
-
-
33750626259
-
Modulating target site selection during human immunodeficiency Virus DNA integration in vitro with an engineered tethering factor
-
A Ciuffi TL Diamond Y Hwang HM Marshall FD Bushman 2006 Modulating target site selection during human immunodeficiency Virus DNA integration in vitro with an engineered tethering factor Hum Gene Ther 17 960 967
-
(2006)
Hum Gene Ther
, vol.17
, pp. 960-967
-
-
Ciuffi, A.1
Diamond, T.L.2
Hwang, Y.3
Marshall, H.M.4
Bushman, F.D.5
-
103
-
-
0033801353
-
SAF-Box, a conserved protein domain that specifically recognizes scaffold attachment region DNA
-
M Kipp F Gohring T Ostendorp CM van Drunen R van Driel M Przybylski FO Fackelmayer 2000 SAF-Box, a conserved protein domain that specifically recognizes scaffold attachment region DNA Mol Cell Biol 20 7480 7489
-
(2000)
Mol Cell Biol
, vol.20
, pp. 7480-7489
-
-
Kipp, M.1
Gohring, F.2
Ostendorp, T.3
Van Drunen, C.M.4
Van Driel, R.5
Przybylski, M.6
Fackelmayer, F.O.7
-
104
-
-
0037072818
-
Involvement of a bifunctional, paired-like DNA-binding domain and a transpositional enhancer in Sleeping Beauty transposition
-
Z Izsvák D Khare J Behlke U Heinemann RH Plasterk Z Ivics 2002 Involvement of a bifunctional, paired-like DNA-binding domain and a transpositional enhancer in Sleeping Beauty transposition J Biol Chem 277 34581 34588
-
(2002)
J Biol Chem
, vol.277
, pp. 34581-34588
-
-
Izsvák, Z.1
Khare, D.2
Behlke, J.3
Heinemann, U.4
Plasterk, R.H.5
Ivics, Z.6
|